Presentation
We present a menopausal female with the acquired hypertrichosis lanuginosa (AHL) as an initial clinical presentation of rectal adenocarcinoma, unusually associated with paraneoplastic cerebellar degeneration (PCD) and disseminated intravascular coagulation [ncbi.nlm.nih.gov]
Bilaterally symmetrical vitiliginous macules were present on the ear and preauricular region. [ijdvl.com]
Readers are guided through the maze that too often lies between the presenting skin complaint and its final diagnosis and treatment. [books.google.com]
Two cases of hypertrichosis lanuginosa with malignancy (lymphoma and uterine cancer) are presented and added to the 9 in the literature. Lymphoma and uterine cancer are previously unreported as associated with hypertrichosis lanuginosa. [experts.umich.edu]
Entire Body System
- Short Stature
Patients affected by this syndrome often show prenatal and postnatal growth retardation, short stature with short hands and feet and psychomotor delay. [ijponline.biomedcentral.com]
Some cases show that short stature and developmental abnormalities are associated with it [ 3 ]. [emedicalhub.com]
stature 1.2 Palms and soles 1.3 Auricle --> men 1.4 Eyebrows 1.5 Eyelashes 1.6 Nasal tip men 1.7 Anterior cervical neuropathies, mr 1.8 Posterior cervical kyphoscoliosis 1.9 Mammary line (polythelia) urinary tract abn 2) Congenital melanocytic nevi 3 [quizlet.com]
Skin
- Hirsutism
Synonyms Acquired hypertrichosis lanuginosa Androgen dependent hirsutism Androgen-dependent hirsutism Familial hirsutism Hirsutism (excess body hair) Hirsutism in female, androgen dependent Hirsutism, familial Hirsutism, idiopathic Hypertrichosis Hypertrichosis [icd9data.com]
(approximate) ICD-10-CM Siblings (same level / similar specificity) of L68.1: L68.0 - Hirsutism L68.2 - Localized hypertrichosis L68.3 - Polytrichia L68.8 - Other hypertrichosis L68.9 - Hypertrichosis, unspecified [emedcodes.com]
Similar Codes ICD-10 Code ICD-10 Description L68 Hypertrichosis L68.0 Hirsutism L68.2 Localized hypertrichosis L68.3 Polytrichia L68.8 Other hypertrichosis L68.9 Hypertrichosis, unspecified This page was last updated on: 10/1/2018 [healthprovidersdata.com]
Hirsutism is quantified by the Ferriman–Gallwey scale, with scores of 6–8 considered mildly hirsute, 8–15 serious, and >15 overt hirsutism. Other signs of hyperandrogenism are acne, oligo- or amenorrhea, and androgenetic alopecia. [en.tzermias.gr]
2) Adrenal: DHEAS - Central (pubic triangle to central upper abdomen, presternal to neck) hirsutism - Pituitary: ACTH, prolactin 3) Drug-induced hirsutism: - Lateral face and back Classification & clinical features 1)Constitutional or dermatologic hirsutism [quizlet.com]
Workup
WORKUP Diagnosis of hypertrichosis is dependent on physical examination with characterization of the hair type involved, pattern of hair growth, and age of initial presentation. [plasticsurgerykey.com]
Dexamethasone suppression test Cushing's syndrome Treatment - Depends on cause that has been identified by hormonal workup 1) Adrenal (see below) 2) Ovarian (see below) Topical therapies 1) Top spironolactone 1-3% 2) Eflornithine 15% cr Cosmetic therapies [quizlet.com]
Treatment
Readers are guided through the maze that too often lies between the presenting skin complaint and its final diagnosis and treatment. [books.google.com]
There is no specific treatment for hypertrichosis lanuginosa acquisita. [checkorphan.org]
What is the treatment for acquired hypertrichosis lanuginosa? The main goal of treatment is to treat the underlying cancer. [dermnetnz.org]
An average of 20% hair is lost with each treatment. Hence, multiple treatments are required to achieve satisfactory results. [e-ijd.org]
Prognosis
Prognosis - Hypertrichosis lanuginosa- acquired Not supplied. Treatment - Hypertrichosis lanuginosa- acquired The main goal of treatment is to treat the underlying cancer. [checkorphan.org]
Treatment: Usually indicative of a poor prognosis, there is no practical therapy of the hypertrichosis per se, other than shaving or cream depilatories. Back to Dermatology Glossary - H Index | Back to Dermatology Glossary Index [skincareguide.ca]
Because acquired hypertrichosis lanuginosa typically occurs late in the course of the malignancy, the overall prognosis is poor. However, regression of hair growth is known to occur if the tumour is treated or removed. [dermnetnz.org]
Prognosis There is no change in lifespan in patients with congenital Ambras syndrome. [babymed.com]
The prognosis is related to the pathological events associated with the hair disorder, in particular to the epilepsy and cardiac or renal anomalies. [ijponline.biomedcentral.com]
Etiology
We considered that CEA might be an important etiological factor of this disease. [ncbi.nlm.nih.gov]
Despite an attempt to find etiologic factors in our patients and in the literature, none could be elicited. AB - Hypertrichosis lanuginosa is a pathologic state characterized by an excessive, new growth of fine, fetal hair. [experts.umich.edu]
Export Citation: APA/MLA Format Download EndNote Download BibTex MeSH Terms Descriptor/Qualifier: Aged Breast Neoplasms / complications* Carcinoma, Ductal, Breast / complications* Eyebrows Eyelashes Female Humans Hypertrichosis / etiology* Paraneoplastic [biomedsearch.com]
Br J Dermatol 165(Suppl 3):19–23 CrossRef PubMed Google Scholar Paul LJ, Cohen PR, Kurzrock R (2012) Eyelash trichomegaly: review of congenital, acquired, and drug-associated etiologies for elongation of the eyelashes. [link.springer.com]
We considered that CEA might be an important etiological factor of this disease. © 1978 S. [karger.com]
Epidemiology
One medicinal option suppresses testosterone by increasing the sex hormone-binding globulin. [ 28 ] Another controls the overproduction of hair through the regulation of a luteinizing hormone. [ 28 ] Epidemiology Congenital forms of hypertrichosis are [dictionnaire.sensagent.leparisien.fr]
MANAGMENT, EPIDEMIOLOGY, SOCIAL and CULTURE There is no cure for any congenital forms of hypertrichosis. The treatment for acquired hypertrichosis is based on attempting to address the underlying cause. [littlespyeye.wordpress.com]
Epidemiology The incidence of CGH is unknown, but held to be essentially rare. The incidence is notably higher when the hypertrichosis is one of several signs involved in a complex syndrome. [ijponline.biomedcentral.com]
Pathophysiology
[…] trigger acquired localized hypertrichosis. [ 24 ] Medication induced hair changes are often reversible. [ 25 ] Other Unknown causes The exact genetic mutation which causes congenital circumscribed, localized, and nevoid hypertrichosis is unknown. [ 1 ] Pathophysiology [dictionnaire.sensagent.leparisien.fr]
PATHOPHYSIOLOGY and DIAGNOSIS A number of mechanisms can lead to hypertrichosis. One cause involves areas of the skin that are transforming from the small vellus type to the larger terminal type. [littlespyeye.wordpress.com]
Prevention
0% Emergent - ED Care Needed - Preventable/Avoidable - 0% Emergent - ED Care Needed - Not Preventable/Avoidable - 0% Primary diagnosis of injury 0% Primary diagnosis of mental health problems 0% Primary diagnosis of substance abuse 0% Primary diagnosis [medicbind.com]
Prevention - Hypertrichosis lanuginosa- acquired Not supplied. Diagnosis - Hypertrichosis lanuginosa- acquired Not supplied. Prognosis - Hypertrichosis lanuginosa- acquired Not supplied. [checkorphan.org]
Rapidly find the answers you need with separate sections on diseases and disorders, differential diagnosis, clinical algorithms, laboratory results, and clinical preventive services, plus an at-a-glance format that uses cross-references, outlines, bullets [books.google.com]
Hypertrichosis has no cure, and you can’t do anything to prevent the congenital form of the disease. The risk of certain forms of acquired hypertrichosis may be lowered by avoiding certain medications, such as minoxidil. [healthline.com]