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Acquired Ichthyosis


  • We present an update on AI to provide clinicians with direction regarding the assessment and treatment of patients presenting with AI. An algorithm for the evaluation of patients presenting with AI is provided.[ncbi.nlm.nih.gov]
Plantar Hyperkeratosis
  • Fig. 1 a Facial skin xerosis. b Large rhomboidal scales covering most of the body. c Dry skin with rhomboidal scales on the lower extremities. d Plantar hyperkeratosis.[karger.com]
  • OBJECTIVES: Elucidation of the pattern of acquired ichthyosis in HTLV-I-associated myelopathy.[ncbi.nlm.nih.gov]
  • Granulomatous mycosis fungoides presenting as an acquired ichthyosis. ( 12653708 ) Eisman S...Whittaker SJ 2003 35 Histopathological and immunohistochemical assessment of acquired ichthyosis in patients with human T-cell lymphotropic virus type I-associated myelopathy[malacards.org]
Spastic Quadriplegia
  • Quadriplegia, and Mental Retardation Ichthyosis, Split Hairs, and Amino Aciduria Ichthyosis-Mental Retardation Syndrome with Large Keratohyalin Granules in the Skin Jagell Holmgren Hofer Syndrome Keratosis Follicularis Spinulosa Decalvans, X-Linked Koone[rgd.mcw.edu]
  • Syndrome Ichthyosis Hystrix Gravior Ichthyosis Hystrix, Curth Macklin Type Ichthyosis Prematurity Syndrome Ichthyosis Tapered Fingers Midline Groove Up ichthyosis vulgaris Ichthyosis, Mental Retardation, Dwarfism, and Renal Impairment Ichthyosis, Spastic Quadriplegia[rgd.mcw.edu]


  • Because AI has been linked to a variety of conditions, the workup of a patient presenting with this finding can be complex.[ncbi.nlm.nih.gov]


  • The prognosis and treatment of generalized Kaposi's sarcoma is discussed.[ncbi.nlm.nih.gov]


  • The prognosis and treatment of generalized Kaposi's sarcoma is discussed.[ncbi.nlm.nih.gov]
  • If acquired ichthyosis appears before a systemic disease is diagnosed, the individual will be examined further for the presence of an underlying disorder Prognosis - Acquired ichthyosis Not supplied.[checkorphan.org]
  • Mycosis fungoides: disease evolution and prognosis of 309 Dutch patients. Arch Dermatol 136: 504510. ‏ الصفحة 22 - M, et al. Transformation of mycosis fungoides: clinicopathological and prognostic features of 45 cases.[books.google.com]
  • Prognosis The prognosis for hereditary ichthyosis vulgaris is excellent. Many patients experience improvement of symptoms with age. The prognosis for acquired ichthyosis vulgaris depends on the severity of the underlying systemic disease.[emedicine.medscape.com]


  • [from NCI ] Etiology Semin Oncol 2016 Jun;43(3):331-4. Epub 2016 Feb 23 doi: 10.1053/j.seminoncol.2016.02.030. PMID: 27178684 Okajima R, Oliveira AC, Smid J, Casseb J, Sanches JA Jr PLoS Negl Trop Dis 2013 Nov;7(11):e2546.[ncbi.nlm.nih.gov]
  • Ichthyoses comprise a large group of skin scaling disorders with diverse etiologies. The stereotypic pathophysiology is epidermal hyperplasia and abnormal desquamation, leading to visible accumulation of squames (scales) on the skin’s surface.[ansa.it]
  • A 2018 study identified 607 atopic dermatitis genes and 193 ichthyosis vulgaris ones as differentially expressed when these atopic or ichthyosis vulgaris patients were compared with healthy donors. [20] Etiology Hereditary ichthyosis vulgaris is an autosomal[emedicine.medscape.com]
  • (Etiology) Ichthyosis Vulgaris is caused by an abnormality in the development of the part of the skin called epidermis.[dovemed.com]
  • PubMed View Article Google Scholar Di Giovanna JJ, Robinson-Bostom L: Ichthyosis: etiology, diagnosis, and management. Am J Clin Dermatol. 2003, 4: 81-95. 10.2165/00128071-200304020-00002.[ojrd.biomedcentral.com]


  • Acquired ichthyosis may represent a paraneoplastic syndrome with an underlying cancer, such as undiagnosed multiple myeloma [21] or reflect a serious underlying disorder such as systemic lupus erythematosus. [22] Epidemiology Frequency United States Hereditary[emedicine.medscape.com]
  • […] disease (although a rare non-heritable version called acquired ichthyosis exists): for these reasons it is also known as "Autosomal dominant ichthyosis", "Ichthyosis simplex" and "Common ichthyosis". ( Hereditary and Acquired Ichthyosis Vulgaris, 2013 ) EPIDEMIOLOGY[flipper.diff.org]
  • PubMed View Article Google Scholar Meyer N, Paul C, Feneron D: Psoriasis: an epidemiological evaluation of disease burden in 590 patients. J Eur Acad Dermatol Venereol. 2010, 24: 1075-1082.[ojrd.biomedcentral.com]
Sex distribution
Age distribution


  • Disruption of epidermal growth pathways through inhibition of various receptor tyrosine kinases by ponatinib may offer insights into the pathophysiologic mechanisms behind acquired ichthyosis.[ncbi.nlm.nih.gov]
  • Other Medscape Drugs & Diseases articles on ichthyosis include the following: Pathophysiology Ichthyosis vulgaris is classified as a retention hyperkeratosis.[emedicine.medscape.com]
  • The pathophysiological mechanisms responsible for paraneoplastic ichthyosis remain unclear. Ichthyosis occurs when there is a disruption in the process of cornification, which is complex and involves multiple enzymes.[karger.com]
  • The stereotypic pathophysiology is epidermal hyperplasia and abnormal desquamation, leading to visible accumulation of squames (scales) on the skin’s surface.[ansa.it]


  • Ichthyosis, acquired, Ichthyosis acquisita, Fish scale disease, acquired Symptoms - Acquired ichthyosis Causes - Acquired ichthyosis Prevention - Acquired ichthyosis Not supplied.[checkorphan.org]
  • "Hot Tub Rash" and "Swimmer's Ear" (Pseudomonas) (Centers for Disease Control and Prevention) Contact dermatitis (Medical Encyclopedia) Diaper rash (Medical Encyclopedia) Hot tub folliculitis (Medical Encyclopedia) Pityriasis rosea (Medical Encyclopedia[icdlist.com]
  • This helps prevent dryness, scaling, cracking and build-up of skin. The skin affected by ichthyosis is treated by hydration with alpha-hydroxy acid lotions such as ammonium lactate. People with acquired ichthyosis have normal lifespan.[streetdirectory.com]
  • The main goal of the treatment is to hydrate the skin and to prevent complications such as infection. Use of soap-free cleansers and regular moisturisers are essential.[dermcoll.edu.au]
  • There are no guidelines for preventing the development of ichthyosis.[uvahealth.com]

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