Demographics Patients with AMC may present at in both genders and at any age, though the presentation of children differ. There may be an association with neuro-psychiatric conditions and medications used in this patient group. [bmcgastroenterol.biomedcentral.com]

A rationalisation of the 1350 boxes used throughout the book gives a simpler and clearer presentation of the various categories. [books.google.com]

[…] doi: 10.1007/BF02616842 Acquired megacolon in Chagas' disease: PDF Only Abstract Article Metrics Metrics Summary and Conclusions Summary and ConclusionsIn this excellent presentation, a report is made of the well-established role of T. cruzi in the etiology [journals.lww.com]

Superbly presented with line drawings, high quality radiographic images and colour photographs. Presented in similar form to its sister textbook Davidson’s Principles and Practice of Medicine. [books.google.de]

Diagnosis depends on subjective radiological, endoscopic or surgical findings in the context of a suggestive clinical presentation. This review sets out to investigate diagnostic criteria of AMC. [ncbi.nlm.nih.gov]

• Constipation

  CONCLUSIONS: Slow-transit constipation and acquired megacolon were associated with alteration of ICC and neuronal cells of ENS in the sigmoid colon. [ncbi.nlm.nih.gov]

  Neither is its relationship to other constipation predominant conditions. It may well be that patients with AMC are misdiagnosed as having Constipation Predominant IBS. [bmcgastroenterol.biomedcentral.com]

  Forty-eight patients treated for chronic incapacitating constipation by surgical resection were reviewed. [experts.umn.edu]

  Figure 1 Figure 2 Discussion Chronic constipation is very common and often more difficult to remedy than an acute onset of constipation. [npplweb.com]

• Abdominal Distension

  A 61-year-old male, with long-standing abdominal distension, presented with generalised abdominal pain, shortness of breath, and marked abdominal distension. [nzma.org.nz]

  […] pass either flatus or stool. [ 4 ] It may present insidiously with chronic abdominal distension, constipation, vague and usually colicky lower abdominal discomfort and vomiting. [patient.info]

  The abdominal distension soon after birth in cases of megacolon is a manifestation of a disease picture resembling ileus and does not prove the congenital dilatation of the colon b) The significance attributed to colonic redundancy is based on insufficient [onlinelibrary.wiley.com]

  Case Report A 76-year-old woman admitted to surgery division of our hospital with chronic abdominal pain, abdominal distension, and constipation lasting for 10 days. [ispub.com]

In: Treatment of acquired megacolon in the dog and cat. JAVMA 188, 1412-1416. [vetstream.com]

Simpson: Neonatal Hirschsprung’s disease: Treatment of complete anganglionosis of the colon by the Duhamel operation. Arch. Surg. 87 : 1019, 1963. PubMed Google Scholar 6. [link.springer.com]

Most cases respond to medical treatment. Advanced cases of megacolon and megarectum can be treated surgically by Duhamel technique. [jcol.elsevier.es]

Learn about this topic in these articles: causes, symptoms, and treatment In megacolon …megacolon, or Hirschsprung disease, and acquired megacolon. [britannica.com]

[…] of intestines, physical therapy, sanatorium treatment. [en.medicalmed.de]

Links: pathophysiology clinical features investigation management prognosis [gpnotebook.co.uk]

Prognosis : guarded depending on stage of disease and choice of treatment. Pathogenesis Etiology Often idiopathic - dysfunction of colonic smooth muscle, progressive post-receptor defect in excitation-contraction coupling. [vetstream.com]

Definitive pathophysiology, prognosis, treatment and management of both conditions remain largely unknown; hence, further research is necessary. This study will investigate these conditions during colonoscopy to identify disease specific features. [researchweb.org]

Prognosis The overall mortality in recent studies is less than 5%. [ 1 ] However, the reported mortality rates in some studies are as high as 20-25%, depending on the interval between diagnosis and treatment. [patient.info]

There are three etiological types of megacolon: acute, chronic, and toxic megacolon. [amboss.com]

[…] doi: 10.1007/BF02616842 Acquired megacolon in Chagas' disease: PDF Only Abstract Article Metrics Metrics Summary and Conclusions Summary and ConclusionsIn this excellent presentation, a report is made of the well-established role of T. cruzi in the etiology [journals.lww.com]

It can also be classified according to etiology. [4] Signs and symptoms External signs and symptoms are constipation of very long duration, abdominal bloating, abdominal tenderness and tympany, abdominal pain, palpation of hard fecal masses and, in toxic [ipfs.io]

It can also be classified according to etiology. [ 4 ] Signs and symptoms External signs and symptoms are constipation of very long duration, abdominal bloating, abdominal tenderness and tympany, abdominal pain, palpation of hard fecal masses and, in [dictionnaire.sensagent.leparisien.fr]

Pathogenesis Etiology Often idiopathic - dysfunction of colonic smooth muscle, progressive post-receptor defect in excitation-contraction coupling. Secondary to colonic obstruction: Extraluminal compression, eg pelvic fracture. [vetstream.com]

Epidemiology Frequency United StatesNo large-scale studies have been conducted to determine prevalence/incidence of acquired megacolon. InternationalThe most common cause of megacolon worldwide is infection with Trypanosoma cruzi (Chagas disease). [thehealthscience.com]

Chagas megacolon. [3] Of the 34% of asymptomatic patients who demonstrated similar patterns of autoantibodies, 84% of these individuals also had levels of beta1 autoantibody that are typical for Chags cardiomyopathy, which the authors stated mirrored the epidemiologic [emedicine.medscape.com]

Epidemiology Sigmoid volvulus is a leading cause of acute colonic obstruction in South America, Africa, Eastern Europe and Asia but is rare in developed countries such as the USA, UK, Japan and Australia. [ 1 ] Sigmoid volvulus is the third leading cause [patient.info]

Epidemiology of congenital innervation defects of the distal colon. [jcol.elsevier.es]

BACKGROUND: The pathophysiology of constipation is not clearly identified as yet, and the interstital cells of Cajal (ICC), known to generate the slow wave activity and to be involved in intestinal neurotransmission and the enteric nervous system (ENS [ncbi.nlm.nih.gov]

Links: pathophysiology clinical features investigation management prognosis [gpnotebook.co.uk]

Novel concepts in the diagnosis, pathophysiology and management of idiopathic megabowel. [bmcgastroenterol.biomedcentral.com]

Pathophysiology Failure of motor function or obstruction to passage of feces → loss of colonic motor activity → normal defecation prevented over prolonged period → colon distends → further muscle degeneration → colon flaccid and filled with dry, hard [vetstream.com]

[…] those who have undergone a major surgical procedure Idiopathic ; possible factors include: Electrolyte imbalance Trauma ; major surgery Hypothyroidism Drugs ; (e.g., anticholinergic drugs, opioid analgesics, antipsychotics, calcium channel blockers ) Pathophysiology [amboss.com]

Children will also receive fluids to prevent dehydration and shock. [livestrong.com]

Prevention of colon enlargement may be achieved by consumption of food rich in fibers and specific measures against constipation. And timely treatment of inflammatory bowel disease may be another form of prevention against colon enlargement. [ic.steadyhealth.com]

To prevent leakage of the rectal-stump suture, the section and suture must be 3 to 6 cm above the peritoneal reflection. [link.springer.com]

Pathophysiology Failure of motor function or obstruction to passage of feces → loss of colonic motor activity → normal defecation prevented over prolonged period → colon distends → further muscle degeneration → colon flaccid and filled with dry, hard [vetstream.com]

Surgery After conservative treatment, further episodes of volvulus often occur and elective surgery is then frequently required to prevent further recurrence. [patient.info]