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Acquired Osteosclerosis


Presentation

  • A rationalisation of the 1350 boxes used throughout the book gives a simpler and clearer presentation of the various categories.[books.google.com]
  • Relevant laboratorydata are presented in the Table.[documents.tips]
  • Herein we report the clinical presentation and imaging results of the 19th case of HCAO. Clinicians, particularly those caring for a population at risk for HCV infection, should be aware of this uncommon condition.[ncbi.nlm.nih.gov]
  • The skull base in our present patient has been analyzed via 3DCT scan. Case presentations The present patient was referred to the orthopaedic department because of arthrogryposis multiplex.[casesjournal.biomedcentral.com]
Intravenous Drugs
  • A 37-year-old man with a history of intravenous drug use and known to be hepatitis C antibody positive presented with bone pain.[ncbi.nlm.nih.gov]
  • Painful diffuse osteosclerosisafter intravenous drug abuse. Am J Med. 1992;93:371381.3. Whyte MP, Teitelbaum SL, Reinus WR. Doubling skeletal mass during adultlife: The syndrome of diffuse osteosclerosis after intravenous drug abuse.[documents.tips]
  • Painful diffuse osteosclerosis after intravenous drug abuse. Am J Med. 1992; 93: 371-381.[meducator3.net]
  • She had no history of intravenous drug abuse or hepatitis C, never fractured or taken antiresorptive therapy, and her family had low bone mass.[asbmr.org]
  • Internal Medicine 54 777 – 783 . ( doi:10.2169/internalmedicine.54.3448 ) Crossref Search Google Scholar Export Citation 2 Villareal DT Murphy WA Teitelbaum SL Arens MQ Whyte MP 1992 Painful diffuse osteosclerosis after intravenous drug abuse .[edmcasereports.com]
Pseudotumor
  • […] of the gastrointestinal tract in infancy and childhood 508 Benign pneumatosis 509 Reduced intestinal gas 510 Increased distance between the intestinal loops 511 Intraabdominal cysts in children 512 Migratory peritoneal calcifications 514 Peritoneal pseudotumors[books.google.com]
Aspiration
  • […] lungs in the pediatric age 315 Pneumonia pattern in children 316 Acute alveolar disease 317 Lobar pneumonia in children 318 Homogeneous lobar or segmental opacification 319 Round pneumonia 320 Pulmonary round lesions in a pediatric leukemic patient 321 Aspiration[books.google.com]
  • Serum creatinine, prostatic spe-cific antigen, thyroid function studies, fluoride, andvitamin A levels, along with serum and urine immu-noelectrophoresis, bone marrow aspirate and bi-opsy, and urinary heavy metal screening were allnormal.[documents.tips]
  • Bone marrow aspiration is usually dry. A bone marrow biopsy is required to show fibrosis. Fibrosis may not be uniformly distributed and so the biopsy may need to be repeated at a different site.[patient.info]
  • When late in the disease progression an attempt is made to take a sample of bone marrow by aspiration , it may result in a dry tap, meaning that where the needle can normally suck out a sample of semi-liquid bone marrow, it produces no sample because[en.wikipedia.org]
Stridor
  • […] density along the inner wall of the upper chest in the newborn 290 The respiratory system of the older infant chilld and youngster 28 Upper airways narrowing or obstruction in infancy and children 291 Retropharyngeal softtissue thickening in children 292 Stridor[books.google.com]
Hysteria
  • […] oral iron and no evidence of gastroin-testinal bleeding.DISCUSSIONPica is the Latin term for magpie, a collector ofodd materials, and according to Websters1 indicatesa craving for un-natural food, earth, or ashes oc-curring especially in pregnancy or hysteria[documents.tips]

Workup

  • Pain and tenderness may be associated with an irregularly mineralized and expanded ischiopubic synchondrosis, but without positive laboratory findings, further workup is unnecessary.  A biopsy of this synchondrosis should not be obtained because false-positive[slideshare.net]
Bowel Distention
  • distention 484 Malabsorption patterns of the small bowel 486 Fixed stiff small bowel loops 487 Destruction of the small bowel mucosa 488 Deformation of the terminal ileum 489 Lesions mimikig regional enteritis 490 Abnormalities of the ileocecal valve[books.google.com]
Hyperlucent Lungs
  • lung 313 Bilateral underaeration of the lungs in the pediatric age 315 Pneumonia pattern in children 316 Acute alveolar disease 317 Lobar pneumonia in children 318 Homogeneous lobar or segmental opacification 319 Round pneumonia 320 Pulmonary round lesions[books.google.com]
Colonic Stricture
  • stricture or narrowing 496 Segmental colonic narrowing in children 497 Toxic megacolon 498 Distention of the small andor large bowelnonobstructive paralytic ileus 499 Distended large bowel 500 Large bowel obstruction 502 Large retrorectal space 503 Large[books.google.com]

Treatment

  • Make the best clinical decisions with an enhanced emphasis on evidence-based practice and expert opinions on treatment strategies. Zero in on the most relevant and useful references with the aid of a more focused, concise bibliography.[books.google.com]
  • The etio-pathogenesis of HCAO remains obscure but may bear important lessons in bone biology that could lead to new treatment options for osteoporosis.[ncbi.nlm.nih.gov]

Prognosis

  • § Fracture prevalence increases with duration of hemodialysis remains unchanged after renal transplantation · Sites of fractures o Vertebral body (3-25%) o Pubic ramus, rib (5-25%) o Milkman fracture / Looser zones (in 1%) o Metaphyseal fractures o Prognosis[learningradiology.com]
  • See 'Prognosis' section below for details of IPSS.[patient.info]
  • Multisystem organ involvement and aggressive vasculitis can confer a dismal prognosis to these subset of patients.[hepatitis.imedpub.com]
  • It is usually discovered incidentally on radiographic examination, is a mild form of familial osteosclerosis and must be distinguished from osteopetrosis which carries a worse prognosis. A marked increase uptake may be found on bone scintigraphy.[gamma.wustl.edu]
  • However, prognosis is poor with HLA-mismatched grafts. Prednisone , calcitriol , and interferon gamma are effective in some cases. This type of osteopetrosis is autosomal recessive.[msdmanuals.com]

Etiology

  • […] interstitial and granulonodulo alveolar pattern 324 Interstitialreticular pulmonary pattern 326 Disseminated interstitial pneumonitis 327 The miliary pattern of pneumonia 328 Short linear andor wedgeshaped densities 329 Pulmonary edema in infancy and childhood Etiology[books.google.com]
  • Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology.[icd10coded.com]
  • The etiology of Paget’s disease of bone remains unknown, but evidence supports both genetic and viral etiologies.[accessmedicine.mhmedical.com]
  • Etiology The causative lesion is a dural arteriovenous shunt of the medullary emissary vein. The arteriovenous shunt is acquired. It is fed by branches of the spinal meninges.[orpha.net]
  • In addition, it is considered to be a process similar to the formation of tori or enostosis. [6] No research has been done to explore the etiology of this entity at a cellular level. Criteria for identification is available in the literature.[jiaomr.in]

Epidemiology

  • Summary Epidemiology The prevalence is unknown. The syndrome most commonly affects men over the age of 50.[orpha.net]
  • Orwoll ES and Klein RF (2001) Osteoporosis in men: epidemiology, pathophysiology, and clinical characterization. In: Marcus R, Feldman D and Kelsey J (eds) Osteoporosis, 2nd edn, vol. 2, pp. 103–150. San Diego, CA: Academic Press.[els.net]
  • Sicca syndrome Both experimental and epidemiological studies have depicted frequent relation between sicca syndrome and HCV infection.[hepatitis.imedpub.com]
  • Aims and Objectives: To determine the prevalence and epidemiological characteristics of idiopathic osteosclerosis.[jiaomr.in]
  • Epidemiology This is an uncommon disease, with an annual incidence of approximately 0.4 cases per 100,000 [ 3 ]. The prevalence is estimated to be 4-6 per 100,000 population [ 4 ].[patient.info]
Sex distribution
Age distribution

Pathophysiology

  • In a format designed for quick reference, it provides complete information on the symptoms, pathophysiology, diagnosis, and treatment of all common and rare bone and mineral disorders.[books.google.it]
  • Orwoll ES and Klein RF (2001) Osteoporosis in men: epidemiology, pathophysiology, and clinical characterization. In: Marcus R, Feldman D and Kelsey J (eds) Osteoporosis, 2nd edn, vol. 2, pp. 103–150. San Diego, CA: Academic Press.[els.net]
  • Conclusion The skull base malformation complex in patients with dysosteosclerosis/osteosclerosis requires careful evaluation. 3DCT scanning of the skull base and the vertebrae could be useful tools for early recognition of the pathophysiological mechanism[casesjournal.biomedcentral.com]
  • […] antineutrophilic cytoplasmic antibodies (ANCA) are only occasionally detected in HBV-related PAN, unlike the typical PAN. (2) Fye et al reported that the disease activity is proportional to the circulating IC levels, strongly attributing circulating ICs in the pathophysiology[hepatitis.imedpub.com]
  • Bone marrow fibrosis: pathophysiology and clinical significance of increased bone marrow stromal fibres. Br J Haematol. 2007;139:351–62. CrossRef PubMed Google Scholar 56. Thiele J, Laubert A, Vykoupil KF, Georgii A.[link.springer.com]

Prevention

  • In another word, prevention of osteosclerosis not uncommon in the post-menopause population.[teaguardian.com]
  • Prevention of bone disease The best treatment is prevention. And that it was fruitful, you need to know everything about osteosclerosis, what it is and what is called. The main rules of prevention: Exercising.[acikgunluk.net]
  • In some cases, your doctor may prescribe medicines to prevent osteoporosis.[icdlist.com]
  • National Osteoporosis Foundation (2003) Physician's Guide to Prevention and Treatment of Osteoporosis. Belle Mead, NJ: Excerpta Medica.[els.net]
  • That is why medical experts prefer to focus on reducing or alleviating the symptoms, as well as preventing further complications.[hoool.com]

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