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Acquired Porencephaly


Presentation

  • Each diagnosis includes clinical presentation(s) of affected patients, the best sequences for imaging analysis, expected imaging sequences (in both common and uncommon presentations), and imaging examples of key features.[books.google.de]
  • Dyslexia and Development presents the latest findings of neurobiological research, which suggest a link between seemingly minor brain abnormalities and epilepsy, learning disorders, and autism.[books.google.com]
  • .  Presentation and outcome are variable Seizures Hemiparesis Developmental deficits  Usually, the severity of symptoms is related to the amount of brain affected by the abnormality 5.[slideshare.net]
  • Intracranial arachnoid cysts may present with headaches, seizures and hydrocephalus. Spinal arachnoid cysts may present with symptoms of radiculopathy.[icd10data.com]
Hodgkin Lymphoma
  • lymphoma in preexistent intraventricular cyst 542 Intramedullary haemangioblastoma with syrinx 544 Spinal syrinx after compression 546 GRADIENT ECHOES 547 Gradient echoes 549 ACKNOWLEDGEMENTS 552 REFERENCES 554 INDEX 569 حقوق النشر[books.google.com]
  • Lymphoma, Toxic Shock Syndrome, Arthritis, Leishmaniasis, Malignant Histiocytosis, Uveitis, Behcets Disease, Obstructive Lung Disease, Optic Neuritis, Duodenal Ulcer, Neuritis, Tonsillitis, Myasthenia Gravis, Cutaneous Leishmaniasis, Yellow Fever, Nephritis[genecards.weizmann.ac.il]
Multiple Congenital Anomalies
  • congenital anomalies-hypotonia-seizures syndrome / Multiple congenital anomalies-hypotonia-seizures syndrome type 2 / Multiple endocrine neoplasia type 1 / Multiple endocrine neoplasia type 2A / Multiple endocrine neoplasia type 2B / Multiple epiphyseal[gennome.com]
Vascular Disease
  • Primary angiitis of the CNS (PACNS) involves the brain only and is defined as a condition causing neurological and psychiatric deficits with evidence of angiitis by imaging or biopsy, in absence of systemic vasculitis, collagen-vascular disease, or infection[neuropathology-web.org]
Lacrimation
  • Castelijns 475 476 Hypopharyngeal tumour 478 Small supraglottic tumour with lymphatic spread 480 Small glottic tumour 482 ORBITAL AND OCULAR LESIONS 485 Retinoblastoma 487 Melanotic melanoma 488 Amelanotic melanoma 490 Optic glioma 492 Carcinoma of the lacrimal[books.google.com]
  • […] brachydactyly syndrome / Temtamy syndrome / Tendons, extensor, of fingers, anomalous insertion of / Testotoxicosis / Tethered cord syndrome / Tetra-amelia syndrome / Tetraamelia multiple malformations X-linked / Tetraamelia with ectodermal dysplasia and lacrimal[gennome.com]
Strabismus
  • […] tongue hamartoma and polysyndactyly / Heart-hand syndrome, Slovenian type / Heart-hand syndrome, Spanish type / HEC syndrome / Hemangioma thrombocytopenia syndrome / Hemangiomatosis, familial pulmonary capillary / Hemi 3 syndrome / Hemifacial hyperplasia strabismus[gennome.com]
Contusion
  • […] the eye 502 Outer ridge meningeoma 503 TEMPOROMANDIBULAR JOINT 505 504 Anterior luxation with reduction 508 Rotational dislocation 510 TRAUMA 513 512 Chronic subdural haematoma 516 Bilateral subdural haematomas tentorial herniation 518 Haemorrhagic contusions[books.google.com]
Joint Dislocation
  • dislocations, GPAPP type / Chondrodysplasia, Grebe type / Chordoma / Chorea-acanthocytosis / Choroidal dystrophy central areolar / Choroideremia / Christianson syndrome / Chromosome 10p deletion / Chromosome 10p duplication / Chromosome 10q deletion[gennome.com]
Dyslexia
  • The authors focus on the plasticity of the developing nervous system and the possible role of subtle early brain injury in the emergence of these disorders, particularly dyslexia.[books.google.com]

Workup

Gliosis
  • […] with calcification and retraction 526 Lowgrade astrocytoma no progression in two years 528 Periinsular gliosis 529 Refractory partial epilepsy gliosis of the temporal lobe 530 Partial complex epilepsy temporal lobe atrophy 532 POSTOPERATIVE CONDITIONS[books.google.com]
  • Gliosis will develop if the insult is late enough, usually thought to be after the start of the third trimester, although perhaps insults as early as 20 weeks of gestation may result in gliosis 11.[radiopaedia.org]
  • On the other hand, the acquired types are usually single and unilateral, with borders usually showing evidence of old necrotic foci, gliosis, connective scar tissue, and meningeal thickening.[mdedge.com]
  • More mature brains have a greater capacity to develop a glial scar (gliosis) around the cyst. 13 After approximately 30 weeks’ gestation, there is a greater chance of reactive glial scarring. 14 Hydranencephaly represents an extreme form of bilateral[radiologykey.com]

Treatment

  • Neurologists and neurobiologists, psychologists, psycholinguists, psychiatrists, and special educators will find here a guide to more enlightened understanding and more effective treatment of dyslexia.[books.google.com]
  • Phase 1, Phase 2 17 Thrombin Approved, Investigational Interventional clinical trials: # Name Status NCT ID Phase Drugs 1 Inositol to Reduce Retinopathy of Prematurity Terminated NCT01954082 Phase 3 myo-Inositol 5% Injection;Placebo 2 Dobutamine in the Treatment[malacards.org]
  • Treatment Treatment is addressed to alleviating symptoms, not to curing the underlying problem, as there is no treatment to induce the brain to grow missing sections of the cerebrum.[encyclopedia.com]
  • Treatment of hydranencephaly is supportive, with shunting if head growth is excessive. Schizencephaly, which some experts classify as a form of porencephaly, involves the presence of abnormal slits, or clefts, in the cerebral hemispheres.[msdmanuals.com]

Prognosis

  • It is important to separate out enlarged third ventricles from true arachnoid cysts, as the long-term prognosis of these patients will differ.[fetalsono.com]
  • What is the prognosis? The prognosis for individuals with porencephaly varies according to the location and extent of the lesions.[bridges4kids.org]
  • The prognosis in these patients is guarded. Significant mental and motor retardation occurred in nearly all cases. Received September 21, 1973. Accepted February 1, 1974.[pediatrics.aappublications.org]
  • Long-term prognosis depends on the size and location of the lesions, and whether there is a hereditary thrombophilia or vasculopathy. The neonate should be evaluated after birth by a pediatric neurologist. Follow-up brain imaging is recommended.[mhmedical.com]
  • Each individual's prognosis will depend on the location and severity of the lesions on their cerebrum. Resources BOOKS Graham, David I. and Peter L. Lantos. Greenfield's Neuropathology, 6th edition. Bath, UK: Arnold, 1997.[encyclopedia.com]

Etiology

  • Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology.[icd10coded.com]
  • Since Heschl's first description, the term "porencephaly" has been widely used to describe etiologically different brain cavities communicating with either the subarachnoid space or the lateral ventricles.[medlink.com]
  • The same risk factors that cause neonatal and pediatric stroke account also for fetal stroke but no specific etiology is found in 50% of cases. The end result of fetal stroke may be a fluid filled cavity (porencephaly).[neuropathology-web.org]
  • The etiological basis could not be determined in most cases.[docslide.net]
  • These cases lead us to believe that hypoxic ischemic damage of the brain is the etiology of porencephalic cyst when associated with cerebral hemiatrophy or when adjacent ulegyria is present.[link.springer.com]

Epidemiology

  • The distinguished contributors to this volume examine epidemiological and clinical issues that may make the developing brain more vulnerable to environmental and genetic influences, which can in turn lead to abnormal brain plasticity and behavior.[books.google.com]
  • Epidemiology: Arachnoid cysts correspond to about 1% of all intracranial lesions in the general population and about 3% in the pediatric population.[thamburaj.com]
Sex distribution
Age distribution

Pathophysiology

  • Additional information is included concerning the pathophysiology and pathology of the disorders being discussed as well as basic information concerning the causative genes (when appropriate).[books.google.de]
  • Alternate names include epithelial cyst, ependymal cyst, choroid cyst, choroidal-epithelial cyst, and glioependymal cyst. 1 Pathophysiology Initially, neuroepithelial cysts were thought to arise by evagination and sequestration of ependyma or choroidal[radiologykey.com]
  • In this article, the author reviews the clinical features and the pathogenetic aspects of porencephaly and provides an update on the pathophysiology of this disorder.[medlink.com]
  • ARTERIAL ISCHEMIC STROKE (AIS) The pathophysiology and evolution of AIS in children is no different from adults. Most cases present with hemiparesis, seizures, and lethargy.[neuropathology-web.org]
  • Anaemia of prematurity: pathophysiology and treatment. Blood Rev. 2010;24(6):221–225.[managedcaremag.com]

Prevention

  • Effective treatment and prevention strategies for childhood stroke and porencephaly can only be developed once the causes are understood.[clinicaltrials.gov]
  • These results can be used in future economic analyses that explore the economic impact of therapies to prevent preterm birth or for treatment of preterm infants. References Berard A, Le TM, De Vera MA.[managedcaremag.com]
  • Treatment includes physical therapy for rigidity, spasticity, or movement difficulties; medication to prevent seizures ; and, if necessary, the installation of a shunt or drain to remove excess cerebrospinal fluid from the inside of the skull.[encyclopedia.com]
  • Salmon JH (1967) Puncture porencephaly, pathogenesis and prevention. Am J Dis Child. 114: 72–79 Google Scholar 18. Dildy III GA, Smith LG, Moise KJ, Cano LE, Hesketh DE (1991) Porencephalic cyst: a complication of fetal intravascular transfusion.[link.springer.com]

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