Presents comprehensive coverage of valvular heart disease to provide you with a complete reference and one-stop shop for this specialty in cardiac medicine. [books.google.com]

We present a case of a 65-year-old woman, with a known history of breast carcinoma, status after wide excision (T1N0Mx) in 2010, who presented with a 0.6 × 0.5-cm, nontender pink nodule in the right inferior axilla of 1 week duration on the same side [ncbi.nlm.nih.gov]

We present a case of a 65-year-old woman, with a known history of breast carcinoma, status after wide excision (T1N0Mx) in 2010, who presented with a 0.6×0.5-cm, nontender pink nodule in the right inferior axilla of 1 week duration on the same side as [mdanderson.influuent.utsystem.edu]

[…] searches within MalaCards or GeneCards Suite gene sharing: MalaCards organs/tissues related to Acquired Pseudoxanthoma Elasticum: 42 Skin, Liver Articles related to Acquired Pseudoxanthoma Elasticum: # Title Authors Year 1 Acquired pseudoxanthoma elasticum presenting [malacards.org]

• Fatigue

  Patients may complain of fatigue from chronic blood loss or claudication from blood vessel involvement. Slowly, as the disease progresses, patients note more severe skin lesions and there may be cardiovascular disease like angina and hypertension. [patient.info]

  Intermittent claudication of the arms can also occur and may present as aching, weakness or fatigue on upper extremity exertion. Occlusion of vessels has been demonstrated in arteriograms of the arms [53]. [plasticsurgerykey.com]

• Surgical Procedure

  procedures and methods, including oculoplastic, corneal, and glaucoma surgery. [books.google.com]

• Lymphedema

  Applicable To Callus Clavus palmaris et plantaris (congenital) (inherited) Q82.8 ICD-10-CM Codes Adjacent To Q82.8 Q81.8 Other epidermolysis bullosa Q81.9 Epidermolysis bullosa, unspecified Q82 Other congenital malformations of skin Q82.0 Hereditary lymphedema [icd10data.com]

• Thrombosis

  Am J Dermatopathol 1996 Aug;18(4):396-9 Abstract quote Calciphylaxis is a rare condition of widespread calcification of tissues and blood vessels with accompanying vascular thrombosis and ischemic necrosis. [thedoctorsdoctor.com]

• Fracture

  They are fine fractures in Bruch’s membrane along which small new blood vessels form (neovascularization). [dermatologyadvisor.com]

• Skin Disease

  The two patients had submucosal yellowish nodular lesions similar to the xanthoma-like skin lesions seen in the disease. [thedoctorsdoctor.com]

  NIH: National Institute of Arthritis and Musculoskeletal and Skin Diseases Acrodermatitis (Medical Encyclopedia) Cryotherapy (Medical Encyclopedia) Cutaneous skin tags (Medical Encyclopedia) Dry skin -- self-care (Medical Encyclopedia) Erythema multiforme [icdlist.com]

  On advancement of the disease, the skin may become loose, lax and redundant and it hangs down in folds producing the typical plucked chicken appearance [10]. [ijcasereportsandimages.com]

  Uitto J, Shamban A (1987) Heritable skin diseases with molecular defects in collagen or elastin. DermatolClin 5:63-84. [omicsonline.org]

• Hyperkeratosis

  Familial benign pemphigus Familial focal facial dermal dysplasia Familial multiple fibrofolliculoma Fibrofolliculoma Fibrotic disorder of skin Finding of palmar crease Flexural Darier's disease Flynn-Aird syndrome Focal dermal hypoplasia Follicular hyperkeratosis [icdlist.com]

  […] nigricans Hereditary benign acanthosis nigricans with insulin resistance Hereditary diffuse palmoplantar keratoderma Hereditary erythrokeratolysis Hereditary follicular keratoses Hereditary palmoplantar keratoderma Howel Evans syndrome Howel-Evans' syndrome Hyperkeratosis [icd9data.com]

  Q82.4 Ectodermal dysplasia (anhidrotic) 2016 2017 2018 2019 Billable/Specific Code POA Exempt Type 1 Excludes Ellis-van Creveld syndrome ( Q77.6 ) hydrotic Q82.8 Elastic skin Q82.8 Elastoma (juvenile) Q82.8 Gyrate scalp Q82.8 Hailey-Hailey disease Q82.8 Hyperkeratosis [icd10data.com]

• Sparse Hair

  It is characterized by poikilodermatous skin changes, sparse hair, cataracts, small stature, skeletal abnormalities, and an increased predisposition to cancer, particularly osteosarcoma. [icd10data.com]

• Suggestibility

  We encountered 3 patients who developed clinical and histopathological evidence of PXE after liver transplantation, suggesting that PXE could have been acquired from the transplanted organ. [ncbi.nlm.nih.gov]

  These results suggested that R1141X and ABCC6del23-29 might have been derived regionally from founder alleles. [thedoctorsdoctor.com]

• Irritability

  […] striadilkomplex-haltigen Creme Localized acquired pseudoxanthoma elasticum after treatment with cream containing Striadril complex (NACH CARE-LEITLINIE) Keywords | Summary | Correspondence | Literature Keywords anti-wrinkle ointment, cosmetic, local irritation [kosmetischemedizin-online.de]

  […] of Dermatology and Venereology, Medical Faculty, Medical University – Sofia, Bulgaria 3 M.D., PhD, Professor in Dermatology and Venereology, Tokuda Hospital – Sofia, Bulgaria KEY WORDS: pseudoxanthoma elasticum, cosmetic, anti-wrinkle ointment, local irritation [gmc-medien.de]

  Maria Balabanova Localized acquired pseudoxanthoma elasticum after treatment with cream containing Striadril complex (NACH CARE-LEITLINIE) Keywords | Summary | Correspondence | References Keywords anti-wrinkle ointment, cosmetic, local irritation, pseudoxanthoma [cosmeticmedicine-online.com]

  Allergies, irritants, your genetic makeup, and certain diseases and immune system problems can cause rashes, hives, and other skin conditions. Many skin problems, such as acne, also affect your appearance. [icdlist.com]

  This theory is supported by reports of pseudoxanthoma elasticum-like syndrome lesions developing in patients with severe ascites, recent abdominal surgery, and in areas of traumatic injury such as elbow flexures. 1, 4, 8 It has been proposed that focal irritation [ispub.com]

As a result, haemoglobin electrophoresis should be considered in the standard workup of every patient presenting with clinical and/or histological features resembling PXE (Figure 21). [cmgg.be]

Herein a clinical case of a localized acquired cutaneous pseudoxanthoma elasticum after treatment with Striadril complex-containing anti-wrinkle cream is described. [kosmetischemedizin-online.de]

diagnosis and treatment. [globenewswire.com]

Prognosis Life expectancy is usually normal, although sudden, unexpected death can occur involving accelerated atherosclerosis with acute myocardial ischaemia, hypertension, mitral valve prolapse, restrictive cardiomyopathy, GI haemorrhage and cerebral [patient.info]

Oxidative stress has also been reported to play an important role in the mechanism of the calcifications and hence in the pathogenesis of PXE. [10] The prognosis in PXE largely depends on the extent of extracutaneous organ involvement, and life expectancy [e-ijd.org]

TREATMENT AND PROGNOSIS CHARACTERIZATION PROGNOSIS PREGNANCY Pseudoxanthoma elasticum and pregnancy. Xiromeritis P, Valembois B. [thedoctorsdoctor.com]

[…] and Martinez-Hernandez proposed the term “localized acquired cutaneous pseudoxanthoma elasticum,” as they believed that the process was “acquired” and was lacking “systemic involvement.” [18] Differentiating the above conditions is important as the prognosis [idoj.in]

This leads to arterial stenosis and heart failure within the first months of life and is associated with a poor prognosis (Figure 20). Although survival to adulthood has been reported, GACI has been often lethal in the first six months of life. [cmgg.be]

These 2 cases represent pseudoxanthoma elasticum-like papillary dermal elastolysis, a recently described entity, the etiology of which remains unclear. [scinapse.io]

Etiology This is an autosomal recessive disorder of connective tissue caused by mutations in the ABCC6 gene. Rarely, it is caused by mutations in GGCX or by a combination of deleterious ABCC6 and GGCX mutations.. [dermatologyadvisor.com]

T hese 2 cases represent pseudoxanthoma elasticum-like papillary dermal elastolysis, a recently described entity, the etiology of which remains unclear. [thedoctorsdoctor.com]

Germany Epidemiology 7.5.2. France Epidemiology 7.5.3. Italy Epidemiology 7.5.4. Spain Epidemiology 7.5.5. United Kingdom Epidemiology 7.5.6. Japan Epidemiology 8. Treatment Algorithm, Current Treatment, and Medical Practices 8.1. [globenewswire.com]

This report defines the prevalence of genital colonization in a large population of women, characterizes the women with S. aureus, and describes epidemiologic features of genital carriage. ‎ Página 50 - Lautenschlager S, Eichmann A. [books.google.es]

Epidemiology Pseudoxanthoma elasticum (PXE) is a recessive disorder with a prevalence of between 1 in 25,000 and 1 in 100,000. [ 1 ] It is caused by mutations in the ABCC6 gene on chromosome 16p13.1. [patient.info]

Pathophysiology 5.4. Risk Factors 5.5. Diagnosis 6. Patient Journey 7. Pseudoxanthoma Elasticum Epidemiology and Patient Population 7.1. Epidemiology Key Findings 7.2. Assumptions and Rationale: 7MM 7.3. Epidemiology Scenario: 7MM 7.4. [globenewswire.com]

Despite growing insights in the clinical diversity and pathophysiological mechanisms of this disease spectrum, a significant number of questions remain. [frontiersin.org]

Causes 2.5.Pathophysiology 2.6. Pseudoxanthoma Elasticum Diagnosis 2.6.1. Diagnostic Guidelines 3. Pseudoxanthoma Elasticum Current Treatment Patterns 3.1. Pseudoxanthoma Elasticum Treatment Guidelines 4. [delveinsight.com]

These pathophysiological mechanisms are however not mutually exclusive and display significant crosstalk. Figure 1: Schematic representation of the pathophysiological mechanisms leading to ectopic mineralization. [cmgg.be]

Pseudoxanthoma elasticum: a clinical, pathophysiological and genetic update including 11 novel ABCC6 mutations. J Med Genet. 2005 Dec;42(12):881-92. Epub 2005 May 13. Review. Dabisch-Ruthe M, Kuzaj P, Götting C, Knabbe C, Hendig D. [ghr.nlm.nih.gov]

The most important aspect of treatment is to ensure that complications from blood vessel involvement are prevented or dealt with speedily by the appropriate specialist. [dermnetnz.org]

Alternatively, a lack of functioning MRP6 may impair the transport of a substance that would normally prevent mineralization, leading to the abnormal accumulation of calcium and other minerals characteristic of PXE. [ghr.nlm.nih.gov]

Is chronic lung disease in low birth weight infants preventable? A survey of eight centers. ‎ Página 84 - Tanner JM, Whitehouse RH, Marubini E, Resele LF. The adolescent growth spurt of boys and girls of the Harpenden growth study. ‎ [books.google.es]

There is no means of prevention and there is no antenatal test for the condition. [patient.info]