Edit concept Question Editor Create issue ticket

Acrocyanosis


Presentation

  • We present a case of an adult woman who presented with unilateral upper limb acrocyanosis and hypertension which was secondary to EAP and resolved completely after surgical removal of the tumour.[ncbi.nlm.nih.gov]
Enuresis
  • An 11 year old girl who was being treated for enuresis with imipramine developed acrocyanosis of the hands and feet. All biochemical and haematological investigations gave normal results.[ncbi.nlm.nih.gov]
Lymphadenopathy
  • A 75-year-old female patient presented with fever, weight loss, general malaise and multiple lymphadenopathy for 2 months. During admission, supportive treatment was given and several episodes of acrocyanosis were relieved by oxygen inhalation.[ncbi.nlm.nih.gov]
Fishing
  • B vitamins; Vitamin C; Fish oil in capsules; Calcium pills. Vasodilators. No-Spa; Papaverine; External treatment.[vascular.vsebolezni.com]
Localized Pain
  • In addition, there is usually no associated trophic skin changes, localized pain, or ulcerations.[en.wikipedia.org]
Hepatomegaly
  • Examination revealed low body mass index (19.6 kg/m 2 ), acrocyanosis [Figure 1], and tender hepatomegaly. Rest of the systemic examination was essentially normal.[idoj.in]
Cyanosis
  • Pernio (Chilblains) Cyanosis Peripheral artery occlusive disease Raynaud's phenomenon[en.wikipedia.org]
  • [acro- G. kyanos, blue, -osis, condition] acrocyanosis /ac·ro·cy·a·no·sis/ ( -si″ah-no sis ) cyanosis of the limbs with discoloration of the skin of digits, wrists, and ankles, and profuse sweating and coldness of digits. acrocyanosis symmetrical cyanosis[medical-dictionary.thefreedictionary.com]
  • CONSUMERS: Click here for the Consumer Version Topic Resources Acrocyanosis is persistent, painless, symmetric cyanosis of the hands, feet, or face caused by vasospasm of the small vessels of the skin in response to cold.[merckmanuals.com]
  • We performed an extensive literature review to summarize existing knowledge about the demographics, pathology, diagnosis, and treatment of this condition. acrocyanosis arterial occlusive disease arteries blood flow velocity capillaries chilblains cyanosis[mayoclinic.pure.elsevier.com]
  • All rights reserved. noun cyanosis of the extremities; can occur when a spasm of the blood vessels is caused by exposure to cold or by strong emotion Etymologies from Wiktionary, Creative Commons Attribution/Share-Alike License From acro- ‎ cyanosis[wordnik.com]
Hyperhidrosis
  • Acrocyanosis is symmetric, painless, discoloration of different shades of blue in the distal parts of the body that is marked by symmetry, relative persistence of the skin color changes with aggravation by cold exposure, and frequent association with local hyperhidrosis[mayoclinic.pure.elsevier.com]
  • The colour change has relative persistence with aggravation by cold exposure, and the condition is frequently associated with localised hyperhidrosis.[pcds.org.uk]
  • Anyways, basically, acrocyanosis is the relatively harmless discoloration of the extremities accompanied by hyperhidrosis due to the fact that the capillaries leading to these extremities close up.[dailystrength.org]
  • Arterial pulses are normal, and there is no proximal pallor, ulceration or gangrene . 1,2,4 Clinical features of acrocyanosis may also include: Hyperhidrosis of hands and feet Cold hands and feet Swelling of digits Secondary acrocyanosis The presentation[dermnetnz.org]
Increased Sweating
  • While the color improves in the summer, she experiences increased sweating of hands and feet. She has no significant medical history and takes no medications. Extensive medical workup has been unrevealing.[mhmedical.com]

Workup

  • Extensive medical workup has been unrevealing. The blue color resolves almost entirely when her hands or feet are elevated in a supine position for a few minutes.[mhmedical.com]
  • Since our patient's clinical presentation (age, sex, clinical features) and blood workup was consistent with primary RP, he was not evaluated for capillary nailfold abnormalities.[link.springer.com]
Hyperviscosity
  • Sometimes the reason is clot formation because of the blood is too thick (“hyperviscosity”). Some other reasons include dysregulation of vascular tone and accumulation of toxins such as methemoglobin.[angiologist.com]
Liver Biopsy
  • Liver biopsy revealed tumor cells arranged in a trabecular nest of uniform cells separated by delicate vascular stroma and stained positive with chromogranin and synaptophysin.[idoj.in]

Treatment

  • Long-term interferon treatment has been related to autoimmune side effects. Raynaud's phenomenon has been observed in patients undergoing interferon treatment associated with elevated ANA titers, to cryoglobulinemia or to arterial occlusion.[ncbi.nlm.nih.gov]
  • Regardless of its cause, the benign form typically does not require medical treatment.[en.wikipedia.org]

Prognosis

  • Abstract Raynauds syndrome, acrocyanosis and erythromelalgia are functional vascular diseases that differ with respect to prevalence, clinical picture, therapy, prognosis, and impairment of quality of life.[ncbi.nlm.nih.gov]
  • Prognosis Even though acrocyanosis cannot be cured, the prognosis remains positive. The prognosis is not as good, in the situation that there is an underlying condition causing the acrocyanosis, such as cancer (associated risk of death).[mddk.com]
  • Readers will find full information on the anatomy of the disease, the clinical picture, prevalence, diagnosis, prognosis, pathology, pathophysiology, and the author's personal treatment preferences, which are backed by 30 years of professional experience[books.google.com]
  • Treatment and prognosis of secondary acrocyanosis depends on the underlying condition. 1 Limited information is available on many of the epidemiological aspects of primary acrocyanosis, including its precise incidence and prevalence.[thoracickey.com]
  • Prognosis Acrocyanosis is a benign and persistent disease. The main concern of patients is cosmetic. Left untreated, the disease does not worsen. Resources BOOKS Alexander, R. W., R. C. Schlant, and V. Fuster, editors. The Heart. 9th ed.[encyclopedia.com]

Etiology

  • The etiology is uncertain and, given the fact that acrocyanosis is a clinical diagnosis, it is not known whether it is a unique phenomenon or different processes with similar clinical features. 3 There is a possible correlation with estrogen levels in[mhmedical.com]
  • Make sure secondary etiology is ruled out. Faraz Ghoddusi, MD Stacey A. Ghoddusi, MPH Gabriel T. Harris, MD, FAAFP Bibliography Das S, Maiti A. Acrocyanosis: an overview. Indian J Dermatol. 2013;58(6):417–420.[unboundmedicine.com]
  • Acrocyanosis Pathophysiology The exact etiology of acrocyanosis is unknown, but a benign neurohormonal condition may cause the disease.[ehealthwall.com]
  • Thus, the management will vary according to the etiology.[2] References DAS SUDIP, MAITI ARUNASIS. Acrocyanosis: An overview. Indian J Dermatol [online] 2013 December [viewed 30 May 2014] Available from: doi:10.4103/0019-5154.119946 KURKLINSKY A.[explainmedicine.com]
  • Based on his benign clinical course and failure to demonstrate other etiologies contributing to his acrocyanosis, he was diagnosed to have primary RP.[link.springer.com]

Epidemiology

  • Incidence, Prevalence, and Epidemiology Although there is no definitive reporting on its incidence, acrocyanosis shows prevalence in children and young adults than in patients thirty years of age or older.[findmeacure.com]
  • Epidemiologic assessment may be confounded by prevalent factors underlying secondary cases.[mhmedical.com]
  • Epidemiological data suggests that cold climate, outdoor occupation, and low body mass index are significant risk factors for developing acrocyanosis. As expected, acrocyanosis would be more prevalent in women than in men due to differences in BMI.[en.wikipedia.org]
  • Jump to: navigation, search Acrocyanosis Microchapters Home Patient Information Overview Historical Perspective Classification Pathophysiology Causes Differentiating Acrocyanosis from other Diseases Epidemiology and Demographics Risk Factors Screening[wikidoc.org]
  • Treatment and prognosis of secondary acrocyanosis depends on the underlying condition. 1 Limited information is available on many of the epidemiological aspects of primary acrocyanosis, including its precise incidence and prevalence.[thoracickey.com]
Sex distribution
Age distribution

Pathophysiology

  • Trials.gov US National Guidelines Clearinghouse NICE Guidance FDA on Acrocyanosis pathophysiology CDC on Acrocyanosis pathophysiology Acrocyanosis pathophysiology in the news Blogs on Acrocyanosis pathophysiology Directions to Hospitals Treating Acrocyanosis[wikidoc.org]
  • Readers will find full information on the anatomy of the disease, the clinical picture, prevalence, diagnosis, prognosis, pathology, pathophysiology, and the author's personal treatment preferences, which are backed by 30 years of professional experience[books.google.com]
  • Acrocyanosis Pathophysiology The exact etiology of acrocyanosis is unknown, but a benign neurohormonal condition may cause the disease.[ehealthwall.com]
  • Such factors may be environmental or not easily identifiable, making it difficult to discern primary and secondary cases. 1, 5 In secondary acrocyanosis, prevalence and incidence vary depending on the underlying condition. 1, 6, 7 ETIOLOGY AND PATHOPHYSIOLOGY[mhmedical.com]
  • For this purpose, a standardised method, as the cooling-rewarming challenge, could verify the several pathophysiological hypotheses proposed for vascular acrosyndromes.[ncbi.nlm.nih.gov]

Prevention

  • Acrocyanosis Prevention Although acrocyanosis has not been found to directly be caused by certain factors, prevention can still be implemented.[ehealthwall.com]
  • Secondary Prevention Cost-Effectiveness of Therapy Future or Investigational Therapies Case Studies Case #1 Acrocyanosis pathophysiology On the Web Most recent articles Most cited articles Review articles CME Programs Powerpoint slides Images American[wikidoc.org]
  • Treatment Insulated boots to prevent Acrocyanosis Liner Socks to help with Arcocyanosis Generally, the treatment is a common sense approach to preventing cold exposure and keeping the feet dry.[almawiclinic.com]
  • Prevention It is easier to prevent acrocyanosis, which is called hypothermia. You just need to take care of warm clothes and be out in the cold too long. To prevent problems caused by vascular spasm, fit, active and healthy lifestyle.[vascular.vsebolezni.com]
  • Treatment Generally the treatment is a common sense approach to preventing cold exposure and keeping the feet dry.[ahni.com]

Ask Question

5000 Characters left Format the text using: # Heading, **bold**, _italic_. HTML code is not allowed.
By publishing this question you agree to the TOS and Privacy policy.
• Use a precise title for your question.
• Ask a specific question and provide age, sex, symptoms, type and duration of treatment.
• Respect your own and other people's privacy, never post full names or contact information.
• Inappropriate questions will be deleted.
• In urgent cases contact a physician, visit a hospital or call an emergency service!