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2.1
Acrocyanosis
Crocq's Disease

Presentation

We present a case of an adult woman who presented with unilateral upper limb acrocyanosis and hypertension which was secondary to EAP and resolved completely after surgical removal of the tumour. [ncbi.nlm.nih.gov]

Described over a century ago and despite seeming familiarity, it remains a poorly understood condition that shares much in clinical presentation with other conditions characterized by skin color changes in the distal parts of the body. [mayoclinic.pure.elsevier.com]

Cardiovascular

  • Cyanosis

    Pernio (Chilblains) Cyanosis Peripheral artery occlusive disease Raynaud's phenomenon [en.wikipedia.org]

    Raynaud sign - Synonym(s): acrocyanosis Raynaud syndrome - idiopathic paroxysmal bilateral cyanosis of the digits. [medical-dictionary.thefreedictionary.com]

    Topic Resources Acrocyanosis is persistent, painless, symmetric cyanosis of the hands, feet, or face caused by vasospasm of the small vessels of the skin in response to cold. [merckmanuals.com]

Workup

Extensive medical workup has been unrevealing. The blue color resolves almost entirely when her hands or feet are elevated in a supine position for a few minutes. [mhmedical.com]

Since our patient's clinical presentation (age, sex, clinical features) and blood workup was consistent with primary RP, he was not evaluated for capillary nailfold abnormalities. [link.springer.com]

Treatment

Long-term interferon treatment has been related to autoimmune side effects. Raynaud's phenomenon has been observed in patients undergoing interferon treatment associated with elevated ANA titers, to cryoglobulinemia or to arterial occlusion. [ncbi.nlm.nih.gov]

Regardless of its cause, the benign form typically does not require medical treatment. [en.wikipedia.org]

We performed an extensive literature review to summarize existing knowledge about the demographics, pathology, diagnosis, and treatment of this condition. [mayoclinic.pure.elsevier.com]

Treatment Generally the treatment is a common sense approach to preventing cold exposure and keeping the feet dry. [ahni.com]

Prognosis

Prognosis Even though acrocyanosis cannot be cured, the prognosis remains positive. The prognosis is not as good, in the situation that there is an underlying condition causing the acrocyanosis, such as cancer (associated risk of death). [mddk.com]

Treatment and prognosis of secondary acrocyanosis depends on the underlying condition. 1 Limited information is available on many of the epidemiological aspects of primary acrocyanosis, including its precise incidence and prevalence. [thoracickey.com]

Abstract Raynauds syndrome, acrocyanosis and erythromelalgia are functional vascular diseases that differ with respect to prevalence, clinical picture, therapy, prognosis, and impairment of quality of life. [ncbi.nlm.nih.gov]

Readers will find full information on the anatomy of the disease, the clinical picture, prevalence, diagnosis, prognosis, pathology, pathophysiology, and the author's personal treatment preferences, which are backed by 30 years of professional experience [books.google.com]

Prognosis Acrocyanosis is a benign and persistent disease. The main concern of patients is cosmetic. Left untreated, the disease does not worsen. Resources BOOKS Alexander, R. W., R. C. Schlant, and V. Fuster, editors. The Heart. 9th ed. [encyclopedia.com]

Etiology

The etiology is uncertain and, given the fact that acrocyanosis is a clinical diagnosis, it is not known whether it is a unique phenomenon or different processes with similar clinical features. 3 There is a possible correlation with estrogen levels in [mhmedical.com]

Make sure secondary etiology is ruled out. Faraz Ghoddusi, MD Stacey A. Ghoddusi, MPH Gabriel T. Harris, MD, FAAFP Bibliography Das S, Maiti A. Acrocyanosis: an overview. Indian J Dermatol. 2013;58(6):417–420. [unboundmedicine.com]

Acrocyanosis Pathophysiology The exact etiology of acrocyanosis is unknown, but a benign neurohormonal condition may cause the disease. [ehealthwall.com]

Based on his benign clinical course and failure to demonstrate other etiologies contributing to his acrocyanosis, he was diagnosed to have primary RP. [link.springer.com]

Thus, the management will vary according to the etiology.[2] References DAS SUDIP, MAITI ARUNASIS. Acrocyanosis: An overview. Indian J Dermatol [online] 2013 December [viewed 30 May 2014] Available from: doi:10.4103/0019-5154.119946 KURKLINSKY A. [explainmedicine.com]

Epidemiology

Incidence, Prevalence, and Epidemiology Although there is no definitive reporting on its incidence, acrocyanosis shows prevalence in children and young adults than in patients thirty years of age or older. [findmeacure.com]

Epidemiologic assessment may be confounded by prevalent factors underlying secondary cases. [mhmedical.com]

Jump to: navigation, search Acrocyanosis Microchapters Home Patient Information Overview Historical Perspective Classification Pathophysiology Causes Differentiating Acrocyanosis from other Diseases Epidemiology and Demographics Risk Factors Screening [wikidoc.org]

Epidemiological data suggests that cold climate, outdoor occupation, and low body mass index are significant risk factors for developing acrocyanosis. [fi.bab.la]

Epidemiological data suggests that cold climate, outdoor occupation, and low body mass index are significant risk factors for developing acrocyanosis. As expected, acrocyanosis would be more prevalent in women than in men due to differences in BMI. [en.wikipedia.org]

Pathophysiology

Trials.gov US National Guidelines Clearinghouse NICE Guidance FDA on Acrocyanosis pathophysiology CDC on Acrocyanosis pathophysiology Acrocyanosis pathophysiology in the news Blogs on Acrocyanosis pathophysiology Directions to Hospitals Treating Acrocyanosis [wikidoc.org]

Readers will find full information on the anatomy of the disease, the clinical picture, prevalence, diagnosis, prognosis, pathology, pathophysiology, and the author's personal treatment preferences, which are backed by 30 years of professional experience [books.google.com]

For this purpose, a standardised method, as the cooling-rewarming challenge, could verify the several pathophysiological hypotheses proposed for vascular acrosyndromes. [ncbi.nlm.nih.gov]

Acrocyanosis Pathophysiology The exact etiology of acrocyanosis is unknown, but a benign neurohormonal condition may cause the disease. [ehealthwall.com]

Such factors may be environmental or not easily identifiable, making it difficult to discern primary and secondary cases. 1, 5 In secondary acrocyanosis, prevalence and incidence vary depending on the underlying condition. 1, 6, 7 ETIOLOGY AND PATHOPHYSIOLOGY [mhmedical.com]

Prevention

Acrocyanosis Prevention Although acrocyanosis has not been found to directly be caused by certain factors, prevention can still be implemented. [ehealthwall.com]

Secondary Prevention Cost-Effectiveness of Therapy Future or Investigational Therapies Case Studies Case #1 Acrocyanosis pathophysiology On the Web Most recent articles Most cited articles Review articles CME Programs Powerpoint slides Images American [wikidoc.org]

Treatment Insulated boots to prevent Acrocyanosis Liner Socks to help with Arcocyanosis Generally, the treatment is a common sense approach to preventing cold exposure and keeping the feet dry. [almawiclinic.com]

Prevention It is easier to prevent acrocyanosis, which is called hypothermia. You just need to take care of warm clothes and be out in the cold too long. To prevent problems caused by vascular spasm, fit, active and healthy lifestyle. [vascular.vsebolezni.com]

Treatment Generally the treatment is a common sense approach to preventing cold exposure and keeping the feet dry. [ahni.com]

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