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Actinobacillus Infection
Actinobacillus Infect

Presentation

CLINICAL PRESENTATION: A 34-year-old man presented with a 3-month history of acute onset of left-sided retro-orbital pain that progressed to a complete left Cranial Nerve VI palsy and Cranial Nerve V1 and V2 hypesthesia. [ncbi.nlm.nih.gov]

Author Affiliations CHICAGO, ILLINOIS, AND ATLANTA, GEORGIA †Formerly, assistant professor of medicine, University of Chicago School of Medicine (present address, Mary Imogene Bassett Hospital. Cooperstown, New York). [nejm.org]

Evidence of the existence of antigenically different strains of A. seminis is presented. © Publisher Full text loading... Article metrics loading... [journals.co.za]

Entire Body System

  • Fever

    […] experimental infection model mimicking acute Actinobacillus pleuropneumoniae (Ap) infection in swine (Sus scrofa) by aerosol inoculation, the development of a number of typical clinical signs was accompanied by a prototypic acute phase reaction encompassing fever [orbit.dtu.dk]

    […] infection caused fever and respiratory symptoms. [xlink.rsc.org]

    Note: a similar tarsal joint lesion developed following intravenous inoculation of the organism. ( J42 .72.w2) In a rabbit with septicaemia: Anorexia and depression for three days. ( J212 .17.w2) Stomach doughy and filled with ingesta. ( J212 .17.w2) Fever [wildpro.twycrosszoo.org]

    Infective endocarditis: diagnosis, antimicrobial therapy, and management of complications: a statement for healthcare professionals from the Committee on Rheumatic Fever, Endocarditis, and Kawasaki Disease, Council on Cardiovascular Disease in the Young [emedicine.medscape.com]

  • Pain

    CONCLUSION: We present a rare bacterial abscess of the cavernous sinus causing painful ophthalmoplegia. [ncbi.nlm.nih.gov]

    Case Reports Rare Actinobacillus Infection of the Cavernous Sinus Causing Painful Ophthalmoplegia: Case Report Department of Neurosurgery, The Cleveland Clinic Foundation, Cleveland, Ohio Department of Neurosurgery, The Cleveland Clinic Foundation, Cleveland [journals.lww.com]

    Symptoms Inability to eat or drink Drooling/ saliva Rapid loss of condition Painful and swollen tongue Ulcers on tongue Animals may occasionally die from starvation and thirst in the acute stages of the disease. [thecattlesite.com]

    Rare Actinobacillus infection of the cavernous sinus causing painful ophthalmoplegia: case report. Neurosurgery 2002;51:807-810. [PubMed] 6 5. Thjotta TL, Sydnes S. Actinobacillus actinomycetam comitans as the sole infecting agent in a human being. [antimicrobe.org]

  • Dentist

    Sometimes, dentists introduce antibiotics underneath the gumline in affected areas (21). Cardiovascular diseases Chronic dental infections, such as periodontitis, increase the risk for cardiovascular disease. [microbewiki.kenyon.edu]

Respiratoric

  • Pneumonia

    They are in combination a rare cause of a variety of infections such as odontological infections, pneumonia, endocarditis, severe eye infection, and have been reported in traumatic skin ulcers (1–4). [medicaljournals.se]

    Aggregatibacter actinomycetemcomitans pneumonia mimicking lung cancer in a previously healthy 12-year-old child from Saudi Arabia: a case report. Al-Nafeesah A. Al-Nafeesah A. [pubmed.ncbi.nlm.nih.gov]

    RESULTS: During the study period, there were 11 patients with invasive A. actinomycetemcomitans infections, including eight patients with infective endocarditis, one with osteonecrosis and two with pneumonia and chest wall lesions. [ncbi.nlm.nih.gov]

    […] resistance neumonia immunoglobuline anticuerpos mortalidad immunite inmunidad infection bacteriosis leucocyte bacterioses taux de respiration resistance aux maladies histopathology immunity histopathologie sintomas maladie des animaux erythrocytes pathogens pneumonia [agris.fao.org]

    But sometimes the germs spread into the lungs or the bloodstream, and then Hib can cause serious problems such as meningitis and pneumonia. There is a vaccine to prevent Hib disease. [fpnotebook.com]

Gastrointestinal

  • Vomiting

    […] piglets vomissement inmunoglobulina muestreo porcelet respiration rate symptome actinobacillus pleuropneumoniae temperature corporelle serotipos cough infeccion haemoglobin abces abscesos antigenos body temperature antibodies serotype conteo de celulas vomiting [agris.fao.org]

Jaw & Teeth

  • Periodontitis

    Source of suspected periodontal pathogens re-emerging after periodontal treatment. J Clin Periodontol 1996: 23: 601-607. [ Links ] [scielo.isciii.es]

    Page and King 1 recently reviewed the experience of the Communicable Disease Center with A actinomycetemcomitans infections and found 32 patients who all had either bacterial… 43 Citations Actinobacillus actinomycetemcomitans in human periodontal disease [semanticscholar.org]

    Pathology Periodontitis Actinobacillus actinomycetemcomitans is the major cause of periodontitis. [microbewiki.kenyon.edu]

    Lesions in the oral cavity were the probable portals of entry of the microorganism, and included carious teeth, periodontitis or radiotherapy of the ear-nose-throat field, and were noted in nine patients. [ncbi.nlm.nih.gov]

Eyes

  • Painful Ophthalmoplegia

    CONCLUSION: We present a rare bacterial abscess of the cavernous sinus causing painful ophthalmoplegia. [ncbi.nlm.nih.gov]

    Case Reports Rare Actinobacillus Infection of the Cavernous Sinus Causing Painful Ophthalmoplegia: Case Report Department of Neurosurgery, The Cleveland Clinic Foundation, Cleveland, Ohio Department of Neurosurgery, The Cleveland Clinic Foundation, Cleveland [journals.lww.com]

    Rare Actinobacillus infection of the cavernous sinus causing painful ophthalmoplegia: case report. Neurosurgery 2002;51:807-810. [PubMed] 6 5. Thjotta TL, Sydnes S. Actinobacillus actinomycetam comitans as the sole infecting agent in a human being. [antimicrobe.org]

Neurologic

  • Meningism

    Actinobacillus actinomycetemcomitans is a gram-negative coccobacillus that is known to cause a wide array of clinical infections in debilitated patients, including periodontal disease, soft tissue abscess, pleural empyema, endocarditis, cerebral abscess, and meningitis [ncbi.nlm.nih.gov]

    But sometimes the germs spread into the lungs or the bloodstream, and then Hib can cause serious problems such as meningitis and pneumonia. There is a vaccine to prevent Hib disease. [fpnotebook.com]

    Actinobacillus ( Pasteurella ) ureae and A. hominis occur in the respiratory tracts of healthy humans and may be involved in the pathogenesis of sinusitis, bronchopneumonia, and meningitis. [en.wikipedia.org]

    […] infectious disease 2016 2017 2018 2019 Billable/Specific Code Actinobacillus (actinomycetem-comitans) A28.8 ICD-10-CM Codes Adjacent To A28.8 A27 Leptospirosis A27.0 Leptospirosis icterohemorrhagica A27.8 Other forms of leptospirosis A27.81 Aseptic meningitis [icd10data.com]

Workup

Microbiology

  • Actinomyces Israelii

    Schlüsselwörter: Myzetom – Actinobacillus actinomycetemcomitans – Actinomyces israelii Key words: Mycetoma –Actinobacillus actinomycetemcomitans–Actinomyces israelii This is a preview of subscription content, log in to check access. [link.springer.com]

    Necrotizing pneumonia caused by mixed infection with Actinobacillus actinomycetemcomitans and Actinomyces israelii: case report and review. Morris JF, Sewell DL. Morris JF, et al. Clin Infect Dis. 1994 Mar;18(3):450-2. doi: 10.1093/clinids/18.3.450. [pubmed.ncbi.nlm.nih.gov]

    The distinctive name A. actinomycetemcomitans originates from it having been first isolated in association with Actinomyces israelii from patients with cervico-facial actinomycosis ( 31 ). [antimicrobe.org]

  • Aggregatibacter Aphrophilus

    "Reclassification of Actinobacillus actinomycetemcomitans, Haemophilus aphrophilus, Haemophilus paraphrophilus and Haemophilus segnis as Aggregatibacter actinomycetemcomitans gen. nov., comb. nov., Aggregatibacter aphrophilus comb. nov. and Aggregatibacter [en.wikipedia.org]

    Reclassification of Actinobacillus actinomycetemcomitans, Haemophilus aphrophilus, Haemophilus paraphrophilus and Haemophilus segnis as Aggregatibacter actinomyctemcomitans gen. nov., comb. nov., Aggregatibacter aphrophilus comb. nov. and Aggregatibacter [antimicrobe.org]

Treatment

Relevant data regarding clinical presentation, antimicrobial treatment and outcome of these patients were analyzed. [ncbi.nlm.nih.gov]

The treatment with ciprofloxacin was stopped, and the patient has been free of lesion since, 18 months after the last treatment. [medicaljournals.se]

Treatment It is important to begin treatment early, as advanced cases may fail to respond. The most common treatments are iodine therapy or tetracyclines. [thecattlesite.com]

A wide variety of treatments have been used, generally successfully. [antimicrobe.org]

Source of suspected periodontal pathogens re-emerging after periodontal treatment. J Clin Periodontol 1996: 23: 601-607. [ Links ] [scielo.isciii.es]

Prognosis

In a series of 57 cases of A actinomycetemcomitans endocarditis, poor dentition (46%) and abnormal cardiac valves (60%) were found to be predisposing factors. [12] Prognosis The prognosis is quite variable, depending on many factors, such as delay in [emedicine.medscape.com]

Favorable prognosis of patients with prosthetic valve endocarditis caused by gram-negative bacilli of the HACEK group. Am J Med 1988;85:104-107. [PubMed] 3 8. Mitchell RG, Gillespie WA. Bacterial endocarditis due to an Actinobacillus. [antimicrobe.org]

Etiology

Zambon Biology, Medicine Journal of clinical periodontology 1985 A large body of evidence implicates A. actinomycetemcomitans as an important micro-organism in the etiology of localized juvenile periodontitis including an increased prevalence of the organism [semanticscholar.org]

Clinical features, epidemiology, etiology, and pathogenesis. Gen Dent. 1998 Sep-Oct. 46(5):491-7. [Medline]. Lampe AS, Schroijen MA, Smith SJ. [emedicine.medscape.com]

Microbial etiological agents of destructive periodontal diseases. Periodontol 2000. 1994;5:78-111. [3] Haraszthy, V. I., Lally E. T., Haraszthy, G. G. & Zambon, J. J (2002). [microbewiki.kenyon.edu]

Microbial etiological agents of destructive periodontal diseases. Periodontol 2000 1994:5: 78-111. [ Links ] 3. Slots J, Ting M. [scielo.isciii.es]

Epidemiology

Fifteen cases and a review of the English-language literature are presented to define the epidemiology and clinical features of infection due to A. actinomycetemcomitans. [pubmed.ncbi.nlm.nih.gov]

Clinical features, epidemiology, etiology, and pathogenesis. Gen Dent. 1998 Sep-Oct. 46(5):491-7. [Medline]. Lampe AS, Schroijen MA, Smith SJ. [emedicine.medscape.com]

Pathophysiology

Pathophysiology When introduced into healthy tissue, the HACEK group organisms have the potential for abscess formation and invasive disease. [emedicine.medscape.com]

Prevention

There is a vaccine to prevent Hib disease. All children younger than 5 years of age should be vaccinated with the Hib vaccine. Centers for Disease Control and Prevention Definition (MSH) Infections with bacteria of the genus HAEMOPHILUS. [fpnotebook.com]

None of the types of protection prevented from developing the disease and characteristic changes in the lungs. [agris.fao.org]

Prevention There are no vaccines available to treat this disease. Control is best achieved by early recognition and prompt treatment or cases, isolation or disposal of infected animals is recommended. [thecattlesite.com]

Good oral hygiene is required to prevent periodontitis. [microbewiki.kenyon.edu]

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