Presentation
Here we report a case who presented with symptomatic pleural effusion due to opportunistic infection caused by Actinomyces viscosus. [tandfonline.com]
The aim of our present study was to assess the [...] Read more. [mdpi.com]
The lesion presented with an air-fluid level and multiple enhancing septa. [bmcinfectdis.biomedcentral.com]
All patients presented with a tuberculosis-like clinical syndrome and chest radiograph with cavitary disease and features consistent with pulmonary TB as the initial clinical impression. [elsevier.es]
Most people have Actinomyces bacteria in the lining of the mouth, throat, digestive tract, and urinary tract, and it is present in the female genital tract. [medicalnewstoday.com]
Entire Body System
- Swelling
There may be: a hard, painful swelling in the soft tissue of the mouth, known as a “woody” fibrosis an abscess This is the most common form of infection caused by Actinomyces. [medicalnewstoday.com]
Symptoms may include any of the following: Draining sores in the skin, especially on the chest wall from lung infection with Actinomyces Fever Mild or no pain Swelling or a hard, red to reddish-purple lump on the face or upper neck Weight loss The health [medlineplus.gov]
Methods: Here, we describe the case of a 52-years-old patient affected by an asymptomatic, tumor-like tongue swelling, then diagnosed as actinomycosis. [mdpi.com]
Cervicofacial actinomycosis is characterized in the initial stages by soft-tissue swelling of the perimandibular area. [emedicine.medscape.com]
- Fatigue
[…] tissue abscesses, or pus-filled lumps small holes or tunnels in tissue called fistulas that can leak a kind of lumpy pus The severity of symptoms mostly depends on where in the body the infection occurs There may be pain and fever, along with body aches, fatigue [medicalnewstoday.com]
Two weeks before this admission, he complained of fever and chills with dizziness, vomiting, and fatigue. On examination in the emergency room, his body weight was 40 kg, and his BMI was 14. [bmcinfectdis.biomedcentral.com]
- Anemia
CASE REPORT A 17-year-old female presented with generalized lymphadenopathy and anemia of 1 month duration, with fever and bleeding from nose and gums, and skin purpura for 20 days. [tandfonline.com]
Recurrent Nocardia sepsis in a patient with sickle cell anemia receiving continuous deferoxamine. J. Pediatr. Infect. Dis. Soc. 3, e35–e37 (2014). Article Google Scholar Lebeaux, D. et al. Nocardiosis in transplant recipients. Eur. J. Clin. [nature.com]
- Malaise
We defined cases according to their clinical presentation (fever, night sweats, productive cough for many weeks, malaise, weight loss, and hemoptysis) and chest radiograph or CT scan of the chest with findings compatible with pulmonary TB (cavitary lesions [elsevier.es]
Respiratoric
- Hemoptysis
We defined cases according to their clinical presentation (fever, night sweats, productive cough for many weeks, malaise, weight loss, and hemoptysis) and chest radiograph or CT scan of the chest with findings compatible with pulmonary TB (cavitary lesions [elsevier.es]
Gastrointestinal
- Gagging
In brief, PCR test was performed using primers 27F: 5′-AGA GTT TGA TCC TGG CTC AG-3′ and 1525R: 5′-AAG GAG GTG WTC CAR CC-3′13 targeting 16S rRNA gene as the primary target for identification. [nature.com]
Eyes
- Foreign Body Sensation
Six months later, the patient developed burning and foreign body sensation in the throat. Balloon dilatation was performed due to the detection of an esophageal stricture through esophagoscopy. [bmcinfectdis.biomedcentral.com]
Neurologic
- Headache
It can lead to a brain abscess, causing headaches and neurological symptoms. Another rare type affects the skin and bones, usually when the infection spreads from deeper tissues. Actinomycosis can take a variety of forms. [medicalnewstoday.com]
- Asthenia
However, aggressive treatment was not favored in our patient considering his asthenia condition and personal reasons. In summary, actinomycosis is still a disease that poses a considerable diagnostic challenge in clinical settings. [bmcinfectdis.biomedcentral.com]
Workup
We were particularly interested in identifying those cases where Tsukamurella spp. or Rhodococcus spp. were isolated during the clinical workup of cases of presumed pulmonary TB. [elsevier.es]
Actinomyces infections (actinomycoses) are considered to be rare, however, due to the slow-growing and fastidious nature of these microorganisms, many Institutions do not have the capabilities or interest for their full diagnostic workup, therefore their [mdpi.com]
Microbiology
- Gram-Positive Bacteria
Short description Actinomycetes are gram-positive bacteria, which are commonly found in nature. They produce interesting natural products, which are the basis of many of the antibiotics developed so far. [dzif.de]
Members of the Actinomyces genus are non-spore-forming, anaerobic, and aerotolerant Gram-positive bacteria that are abundantly found in the oropharynx. [mdpi.com]
Introduction Actinomycetales order mainly known as aerobic actinomycetes are Gram-positive bacteria with a high guanine-plus-cytosine (GC) content in their genomes1. [nature.com]
Treatment
Full recovery can be expected with treatment. In rare cases, meningitis can develop from actinomycosis. Meningitis is an infection if the membranes covering the brain and spinal cord. This membrane is called the meninges. [medlineplus.gov]
It is important to get early treatment if it occurs. [medicalnewstoday.com]
The only deaths reported during the 6-month treatment period were the patients co-infected with Mycobacterium tuberculosis and Rhodococcus.19 Discussion In the presence of effective treatment, treatment failure of pulmonary TB is considered with continued [elsevier.es]
We emphasize the importance of early diagnosis, and delays in treatment can lead to increased morbidity and mortality. [bmcinfectdis.biomedcentral.com]
Treatment of recalcitrant actinomycosis with ciprofloxacin. J Infect. 1993 Sep. 27(2):177-80. [QxMD MEDLINE Link]. Ferreira Dde F, Amado J, Neves S, Taveira N, Carvalho A, Nogueira R. Treatment of pulmonary actinomycosis with levofloxacin. [emedicine.medscape.com]
Prognosis
Prognosis When actinomycosis is diagnosed early and treated with appropriate antibiotic therapy, the prognosis is excellent. [emedicine.medscape.com]
Although the prognosis of Actinomyces infection is usually favorable under medical treatment, it can still lead to death in patients with extensive involvement or those without early detection. [bmcinfectdis.biomedcentral.com]
Etiology
Other etiologies identified included nontuberculous mycobacteria: two cases of infection due to Mycobacterium kansasii and one case caused by Mycobacterium abscessus. [elsevier.es]
Actinomycosis: etiology, clinical features, diagnosis, treatment, and management. Infect Drug Resist. 2014;7:183–97. PubMed PubMed Central Google Scholar Schaal KP, Lee HJ. Actinomycete infections in humans—a review. Gene. 1992;115(1–2):201–11. [bmcinfectdis.biomedcentral.com]
Epidemiology
Actinomycoses are considered to be rare; however, reliable epidemiological data on their prevalence is lacking. [mdpi.com]
Precise identification of actinomycetes isolates using molecular-based approaches is required for a better understanding of the epidemiology of infection. [nature.com]
Epidemiology Frequency United States Actinomycosis is rare. During the 1970s, the reported annual incidence of actinomycosis in the Cleveland area was 1 case per 300,000 persons. [emedicine.medscape.com]
Pathophysiology
Pathophysiology Actinomycetes are prominent among the normal flora of the oral cavity but less prominent in the lower gastrointestinal tract and female genital tract. [emedicine.medscape.com]
Prevention
The infection can also affect certain women who have had an intrauterine device (IUD) to prevent pregnancy. [medlineplus.gov]
Furthermore, the evaluation of the antibiotic resistance pattern of actinomycetes isolates should not be limited to a period of time and continuous monitoring is required for the prevention of infection and the improvement of therapeutic approaches. [nature.com]
Clin Infect Dis., 32 (2001), pp. 1062-103 [17] Centers for Disease Control and Prevention.. Reported Tuberculosis in the United States 2011. Atlanta, GA: U.. [18] Savini V, Fazii P, Favaro M, AstolfiD, Polilli E, Pompilio A, et al.. [elsevier.es]