Presentation
We present the clinical course and ultrasonographic and radiologic findings of an acute case of isolated bilateral lacrimal gland pseudotumor in a patient with Crohn\{textquoteleft}s disease. [experts.umich.edu]
Case Report A 7 year-old male presented to our OPD with complaints of pain, swelling and irritation, in both eyes for two days. [djo.org.in]
We report a case of the disease that presented with acute dacryoadenitis followed by acute parotitis. [semanticscholar.org]
Eight months later, she presented again with signs of acute left-sided dacryoadenitis, not responding at all to oral antibiotics after 3 days. She was subsequently started on oral steroids, and her symptoms resolved within 48 h. [ncbi.nlm.nih.gov]
Average time to presentation was 2.8 days, and predisposing conditions were found in 45% of cases. Common presenting symptoms were eyelid swelling, pain, redness and diplopia, and common signs were ptosis, discharge and restriction of eye movements. [digital.library.adelaide.edu.au]
Entire Body System
- Swelling
Case Report A 7 year-old male presented to our OPD with complaints of pain, swelling and irritation, in both eyes for two days. [djo.org.in]
Orbital magnetic resonance images revealed mild right eyelid swelling and lacrimal gland enlargement, indicating orbital inflammation. [jstage.jst.go.jp]
Case Report A 24-year-old male developed redness and pain in the right eye and slight swelling of the right upper lid. He reported to some general practitioner who suggested it to be minor insect bite or insect allergy. [ncbi.nlm.nih.gov]
This case is unique since the patient presented to the clinic with an acute onset of bilateral swelling in the upper and lower eyelids. [aaopt.org]
- Pseudotumor
Concurrent orbital pseudotumor and Crohn's disease, although rare, have been described. To the best of our knowledge, pseudotumor isolated to the lacrimal gland (dacryoadenitis) with concurrent Crohn's disease has never been reported. [experts.umich.edu]
Abstract Concurrent orbital pseudotumor and Crohn's disease, although rare, have been described. To the best of our knowledge, pseudotumor isolated to the lacrimal gland (dacryoadenitis) with concurrent Crohn's disease has never been reported. [ncbi.nlm.nih.gov]
To the best of our knowledge, pseudotumor isolated to the lacrimal gland ( dacryoadenitis ) with concurrent Crohn's disease has never been reported. [journals.lww.com]
To the best of our knowledge, pseudotumor isolated to the lacrimal gland (dacryoadenitis) with concurrent Crohn's disease has never been reported. [semanticscholar.org]
- Fever
Infection of the Salivary and Lacrimal Glands 65 10 Deep Neck Infections 73 PART III 77 11 Conjunctivitis 79 12 Keratitis 87 Keratitis Isolates 19932006 88 13 Iritis 97 14 Retinitis 103 15 Endophthalmitis 109 16 Periocular Infections 117 PART IV 121 17 Fever [books.google.com]
Nor did the patient have a fever or any other systemic symptoms. FIGURE 1 Edema of the upper and lower eyelid The swelling was not accompanied by inflammation or fever, but it did impair the patient’s vision. [mdedge.com]
- Severe Pain
[…] even in the absence of severe painful eyelid swelling and redness. [jstage.jst.go.jp]
1 Sarcoidosis presenting with acute dacryoadenitis. ( 29257721 ) 2017 2 [Ophthalmoplegia without severe painful eyelid swelling in acute dacryoadenitis: a case report]. ( 26616487 ) Nakajima N....Ueda M. 2016 3 Sequential right then left acute dacryoadenitis [malacards.org]
In case of an acute one, there is unilateral and severe pain, redness and pressure in the supratemporal region of the orbit and rapid onset is always present. [ic.steadyhealth.com]
- Infectious Mononucleosis
mononucleosis may be different. [italjmed.org]
Most common organisms are Staphylococcus aureus, mumps, infectious mononucleosis, and influenza virus. References Promoted articles (advertising) [radiopaedia.org]
A frequent cause is an associated systemic infection such as mumps, infectious mononucleosis, influenza, or it can be due to a local condition such as trachoma, herpes zoster or staphylococcal infection. [medical-dictionary.thefreedictionary.com]
Acute dacryoadenitis may result from systemic infections such as mumps, measles, influenza, infectious mononucleosis, herpes zoster and gonorrhoea and it can also occur consequent to staphylococcal conjunctivitis [ 1, 3, 4 ]. [ncbi.nlm.nih.gov]
[…] viruses involved in dacryoadenitis are herpes simplex virus, infectious mononucleosis virus, cytomegalovirus, human immune deficiency virus and herpes zoster virus. [1],[2],[3],[4] We assume that our patient was suffering from pharyngoconjunctival fever [nigerianjournalofophthalmology.com]
Gastrointestinal
- Abdominal Pain
The patient had a 3-weeks history of fever, abdominal pain, diarrhoea, aphthous oral lesions, and arthritis. [nature.com]
pain), hematocrit/hemoglobin (gastrointestinal bleeding), ESR, x-ray with barium, abdominal CT Suspected tuberculosis: Purified protein derivative with anergy panel Suspected syphilis: Rapid plasma reagin or Venereal Disease Research Laboratory and fluorescent [entokey.com]
Skin
- Erythema
Swelling and erythema of lids increased with development of limitation of extra ocular movements in all directions. Blood counts revealed leucocytosis. [djo.org.in]
Contact dermatitis with irritation, erythema, and edema. Copyright © VisualDx.com Figure 4. Contact dermatitis with irritation, erythema, and edema. Copyright © VisualDx.com Enlarge Print Figure 5. [aafp.org]
Signs Chemosis, conjunctival injection, mucopurulent discharge, erythema of eyelids, proptosis, ocular motility restriction and swelling of the lateral third of the upper lid are some of the most common signs. [ic.steadyhealth.com]
Among the classic signs of preseptal cellulitis are eyelid edema/erythema/warmth and fever. There are clinical keys that help us distinguish between preseptal and orbital cellulitis. [eyewiki.aao.org]
Eyes
- Lacrimation
[…] gland H04.002 …… left lacrimal gland H04.003 …… bilateral lacrimal glands H04.009 …… unspecified lacrimal gland H04.01 Acute dacryoadenitis H04.011 …… right lacrimal gland H04.012 …… left lacrimal gland H04.013 …… bilateral lacrimal glands H04.019 …… [icd10data.com]
Yet, infectious dacryoadenitis is thought to be caused by ascension of an inciting agent from the conjunctiva through the lacrimal ductules into the lacrimal gland. [emedicine.medscape.com]
To the best of our knowledge, pseudotumor isolated to the lacrimal gland (dacryoadenitis) with concurrent Crohn's disease has never been reported. [experts.umich.edu]
H04.132 Lacrimal cyst, left lacrimal gland H04.133 Lacrimal cyst, bilateral lacrimal glands H04.139 Lacrimal cyst, unspecified lacrimal gland H04.14 Primary lacrimal gland atrophy H04.141 Primary lacrimal gland atrophy, right lacrimal gland H04.142 Primary [icd10coded.com]
Unspecified dacryoadenitis (disorder), Dacryoadenitis NOS (disorder), Dacryadenitis, Dacryoadenitis (disorder), infection; lacrimal gland, inflammation; lacrimal gland, lacrimal gland; infection, lacrimal gland; inflammation, Dacryoadenitis, NOS, Dacryoadenitis [fpnotebook.com]
- Excessive Tearing
Symptoms Swelling of the outer portion of the upper lid, with possible redness and tenderness Pain in the area of swelling Excess tearing or discharge Swelling of lymph nodes in front of the ear Signs and tests Dacryoadenitis can be diagnosed by examination [coordinatedhealth.com]
tearing or discharge Swelling of lymph nodes in front of the ear Complications[edit] Swelling may be severe enough to put pressure on the eye and distort vision. [en.wikipedia.org]
Symptoms Symptoms may include: Swelling of the outer portion of the upper lid, with possible redness and tenderness Pain in the area of swelling Excess tearing or discharge Swelling of lymph nodes in front of the ear Treatment If the cause of dacryoadenitis [account.allinahealth.org]
Symptoms Symptoms may include: Swelling of the outer portion of the upper lid, with possible redness and tenderness Pain in the area of swelling Excess tearing or discharge Swelling of lymph nodes in front of the ear Exams and Tests Dacryoadenitis can [mountsinai.org]
- Chemosis
Patient was empirically started on oral amoxicillin-clavulanic acid, however, the condition worsened with increased conjunctival congestion and chemosis. [djo.org.in]
There was a left-sided periorbital swelling, with chemosis involving the bulbar conjunctiva on the temporal aspect. Ocular motility showed limitation of left-sided abduction with mild limitation of laevoelevation and laevodepression. [casereports.bmj.com]
Signs Chemosis, conjunctival injection, mucopurulent discharge, erythema of eyelids, proptosis, ocular motility restriction and swelling of the lateral third of the upper lid are some of the most common signs. [ic.steadyhealth.com]
Color photo of affected right eye showing lid swelling, purulent discharge, conjunctival injection and chemosis. Axial cuts of orbital CT with contrast showing enlarged, loculated lacrimal gland right orbit. [healio.com]
- Lacrimal Gland Enlargement
CT of orbits revealed right-sided lacrimal gland enlargement, with signs of abscess formation within it. [ncbi.nlm.nih.gov]
Orbital magnetic resonance images revealed mild right eyelid swelling and lacrimal gland enlargement, indicating orbital inflammation. [jstage.jst.go.jp]
Abstract The lacrimal gland is a common site of sarcoidosis in and around the orbit. Dacryoadenitis or lacrimal gland enlargement caused by sarcoidosis most often develops as a silent, chronic inflammatory reaction. [aaopt.org]
Clinical examination and imaging studies demonstrated a left lacrimal gland enlargement. Bilateral anterior uveitis and erythematous nontender cutaneous lesions were also found. [ingentaconnect.com]
- Diplopia
Common presenting symptoms were eyelid swelling, pain, redness and diplopia, and common signs were ptosis, discharge and restriction of eye movements. The most common causative bacteria were Staphylococcus aureus and skin flora. [digital.library.adelaide.edu.au]
Abstract A 48-year-old lorry driver presented with 3 weeks of blurred vision, pain and diplopia. There was a right upper lid ptosis with some restriction of eye movements. [karger.com]
[…] features Age: benign tumors present between 20–40 years of age; malignant tumors present > 40 years of age Unilateral swelling of the lateral orbit Unilateral proptosis : painless in benign tumors ; painful in malignant tumors Restricted eye movement and diplopia [amboss.com]
Workup
Explain which cases of dacryoadenitis warrant additional workup. Describe the management options for dacryoadenitis. [ncbi.nlm.nih.gov]
Clinical Evaluation When a diagnosis of acute dacryoadenitis is suspected, a focused workup of the condition should be initiated. A thorough history and physical is the essential first step. [reviewofophthalmology.com]
Sections Dacryoadenitis Overview Background Pathophysiology Epidemiology Prognosis Show All Presentation History Physical Causes Show All DDx Workup Laboratory Studies Imaging Studies Histologic Findings Show All Treatment Medical Care Consultations Long-Term [emedicine.medscape.com]
Inflammatory causes should prompt a systemic workup. [healio.com]
Microbiology
- Staphylococcus Aureus
Both these samples grew staphylococcus aureus which was resistant to chloramphenicol, but sensitive to ampicillin, gentamicin and ciprofloxacin. [ncbi.nlm.nih.gov]
Kubal, A Garibaldi, DC Dacryoadenitis caused by methicillin-resistant Staphylococcus aureus. Ophthal Plast Reconstr Surg 2008 24 50 – 1 Google Scholar | Medline | ISI [journals.sagepub.com]
Acute onset is most commonly associated with lacrimal gland infection by Staphylococcus aureus. This case is unique since the patient presented to the clinic with an acute onset of bilateral swelling in the upper and lower eyelids. [aaopt.org]
Most common organisms are Staphylococcus aureus, mumps, infectious mononucleosis, and influenza virus. References Promoted articles (advertising) [radiopaedia.org]
The most common causative bacteria were Staphylococcus aureus and skin flora. Lacrimal gland swelling was universally seen on CT, with globe indentation of displacement in 27% of cases. [digital.library.adelaide.edu.au]
- Chlamydia
Other than that, bacteria such as Neisseria gonorrhoeae, staphylococcus, syphilis, chlamydia, or tubercular (TB) bacteria usually can cause the infection. [medigoo.com]
[…] common infectious cause Mumps rubulavirus Cytomegalovirus (CMV) Herpes simplex virus (HSV) Varicella zoster Coxsackie virus Echovirus Bacteria that may be involved include: Gram-positive and gram-negative bacteria Staphylococcus Streptococcus Gonococcus Chlamydia [dovemed.com]
Causes Causes can be infectious like mumps, herpes zoster and echoviruses, bacterial like neisseria gonorrhoeae, Chlamydia trachomatis and borrelia burgdorferi and fungal like parasite, protozoa and histoplasmosis. [ic.steadyhealth.com]
- Chlamydia Trachomatis
trachomatis In rare cases, bacterial infections such as brucellosis, syphilis, Lyme disease, and tuberculosis Fungi that may be involved include: Histoplasma Blastomyces Rarely, parasitic infections through the following organisms: Acanthamoeba (rare [dovemed.com]
Causes Causes can be infectious like mumps, herpes zoster and echoviruses, bacterial like neisseria gonorrhoeae, Chlamydia trachomatis and borrelia burgdorferi and fungal like parasite, protozoa and histoplasmosis. [ic.steadyhealth.com]
trachomatis Mycobacterium leprae Mycobacterium tuberculosis Borrelia burgdorferi [2] Causes of fungal dacryoadenitis (rare) include the following: Histoplasmosis Blastomycosis Parasite (rare) Schistosoma haematobium Protozoa (rare) Acanthamoeba keratitis [emedicine.medscape.com]
- Neisseria Gonorrhoeae
Other than that, bacteria such as Neisseria gonorrhoeae, staphylococcus, syphilis, chlamydia, or tubercular (TB) bacteria usually can cause the infection. [medigoo.com]
Causes Causes can be infectious like mumps, herpes zoster and echoviruses, bacterial like neisseria gonorrhoeae, Chlamydia trachomatis and borrelia burgdorferi and fungal like parasite, protozoa and histoplasmosis. [ic.steadyhealth.com]
gonorrhoeae Treponema pallidum Chlamydia trachomatis Mycobacterium leprae Mycobacterium tuberculosis Borrelia burgdorferi [2] Causes of fungal dacryoadenitis (rare) include the following: Histoplasmosis Blastomycosis Parasite (rare) Schistosoma haematobium [emedicine.medscape.com]
- Borrelia Burgdorferi
Causes Causes can be infectious like mumps, herpes zoster and echoviruses, bacterial like neisseria gonorrhoeae, Chlamydia trachomatis and borrelia burgdorferi and fungal like parasite, protozoa and histoplasmosis. [ic.steadyhealth.com]
burgdorferi [2] Causes of fungal dacryoadenitis (rare) include the following: Histoplasmosis Blastomycosis Parasite (rare) Schistosoma haematobium Protozoa (rare) Acanthamoeba keratitis associated Inflammatory dacryoadenitis Causes of inflammatory dacryoadenitis [emedicine.medscape.com]
[…] disease (PID), and ectopic pregnancy Mycobacterium leprae, also known as Hansen’s coccus spirally and is common in tropical countries, is the bacteria that cause leprosy Mycobacterium tuberculosis is the most common causative factor of tuberculosis Borrelia [symptomscausestreatment.com]
Treatment
The treatment and review of the literature are discussed. [experts.umich.edu]
Two days after treatment with systemic antibiotics he developed iridocyclitis and skin lesions confined to the first division of the trigeminal nerve; therefore, herpes zoster ophthalmicus was diagnosed. [ncbi.nlm.nih.gov]
When a proper diagnosis is established using clinical signs, imaging studies, and laboratory results, treatment of the condition can be initiated. Treatment of the acute form is with oral corticosteroids. [insights.ovid.com]
The mainstay of IgG4-related disease treatment remains tapering doses of glucocorticoids; orbit-involving disease has been treated with corticosteroids; however, a meta-analysis suggests an unsustained response with relapse after treatment cessation [ [karger.com]
Prognosis
Prognosis Acute dacryoadenitis: Prognosis is good. Acute dacryoadenitis is a self-limiting condition in most instances. Chronic dacryoadenitis: Prognosis is dependent on the management of the associated chronic systemic condition. [emedicine.medscape.com]
Clinical course and prognosis: Acute inflammation of the lacrimal gland is characterized by a rapid clinical course and spontaneous healing within eight to ten days. The prognosis is good, and complications are not usually to be expected. [alpfmedical.info]
Etiology
Some of the etiologic factors named by him [jamanetwork.com]
Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. [icd10coded.com]
Dacryoadenitis may be separated into acute and chronic syndromes with infectious or systemic etiology. Pathophysiology The pathophysiology is not understood completely. [emedicine.medscape.com]
Epidemiology
Epidemiology Frequency United States Dacryoadenitis is uncommon; therefore, data about its prevalence are sparse. One in 10,000 ophthalmic patients has dacryoadenitis according to one report. [emedicine.medscape.com]
Beginning with basic science, examination techniques and epidemiology, the following chapters discuss the diagnosis and the medical and surgical treatment of numerous different conditions and diseases that may affect the cornea. [books.google.ro]
References[edit] ^ "Dacryoadenitis: Background, Pathophysiology, Epidemiology". 2017-10-09. External links[edit] Source (NIH/Medline) eMedicine Diseases Database (DDB): 3430 [en.wikipedia.org]
Pathophysiology
Pathophysiology The pathophysiology is not understood completely. Yet, infectious dacryoadenitis is thought to be caused by ascension of an inciting agent from the conjunctiva through the lacrimal ductules into the lacrimal gland. [emedicine.medscape.com]
Pathophysiology Patthophysiology of dacryoadenitis is still not fully understood, according to the experts. [ic.steadyhealth.com]
References[edit] ^ "Dacryoadenitis: Background, Pathophysiology, Epidemiology". 2017-10-09. External links[edit] Source (NIH/Medline) eMedicine Diseases Database (DDB): 3430 [en.wikipedia.org]
Prevention
/Avoidable - 0% Emergent - ED Care Needed - Not Preventable/Avoidable - 0% Primary diagnosis of injury 0% Primary diagnosis of mental health problems 0% Primary diagnosis of substance abuse 0% Primary diagnosis of Alcohol 0% Unclassified 100% You may [medicbind.com]
Mumps can be prevented by vaccination. Gonococcal bacteria can be prevented by using condoms. Other causes cannot be prevented, for example acute dacryoadenitis (dacryoadenitis acuta) – acute inflammation of lachrymal glands. [optometry-today.com]
Prevention Mumps can be prevented by immunization. Infection with gonococcus, the bacteria causing gonorrhea, can be avoided by the use of safe sex practices. Most other causes cannot be prevented. [coordinatedhealth.com]
Prevention[edit] Mumps can be prevented by immunization. Gonococcus, bacteria can be avoided by the use of condoms. Most other causes cannot be prevented. [en.wikipedia.org]