A subset analysis of 21 eyes that presented with light perception/no light perception vision where vitrectomy was not possible demonstrated that intravitreal antibiotic injection improved vision and achieved similar visual gain as in eyes that presented [ncbi.nlm.nih.gov]

[…] approx 7% Injuries including IOFB have higher rates Risk factors Other risk factors: dirty wound, lens capsule rupture, age 50, delayed presentation of more than 24 hours after injury Bacillus and Staphylococcus are common in penetrating trauma with IOFB Workup [eyewiki.aao.org]

There was no additional effect for treatment by primary vitrectomy or intravitreal prednisolone. CONCLUSIONS: Treatment outcome after endophthalmitis is highly dependent on the causative organism. [ncbi.nlm.nih.gov]

There is often a guarded visual prognosis. Figure 1. Inferior hypopyon (pus in the anterior chamber). The cornea is hazy from inflammation. [racgp.org.au]

Gram-negative infections with Pseudomonas also has poor prognosis. Coagulase-negative staphylococci has a very good prognosis. Interventions that delayed more than 24 hours after onset will have worse visual outcomes. [infectiousdiseaseadvisor.com]

Vision prognosis is often poor, even with early and appropriate treatment. Patients whose vision at presentation is count-fingers or worse should be considered for vitrectomy and use of intraocular corticosteroids. [merckmanuals.com]

Clinical course and prognosis: The prognosis for acute microbial endophthalmitis depends on the virulence of the pathogen and how quickly effective antimicrobial therapy can be initiated. [alpfmedical.info]

Posttraumatic cases are commonly infected with streptococcal and gram-negative organisms that are associated with poor visual prognosis. [pubs.sciepub.com]

BACTERIOLOGIC IDENTIFICATION TECHNIQUES Culture Methods The isolation of microorganisms in culture is the reference method for determining the etiology of endophthalmitis. [retinatoday.com]

Any future trials should examine whether adjunctive steroids may be useful in certain clinical settings such as type of causative organism or etiology. [ncbi.nlm.nih.gov]

Etiology of Endophthalmitis, Usual Pathogens and Suggested Initial Therapy Table I. [infectiousdiseaseadvisor.com]

Infectious endophthalmitis can have either an exogenous (following ocular surgery/ penetrating trauma ) or endogenous (hematogenous spread) etiology. [amboss.com]

However, before culture results are available, empiric treatments based on the epidemiological findings in the community may be used. [nature.com]

Outcomes of more than 480 000 cataract surgeries, epidemiologic features, and risk factors. Ophthalmology. 2016;123:295–301. CrossRef PubMed 6. Taban M, Behrens A, Newcomb RL, et al. [springermedizin.at]

Discussion of Epidemiology and Treatment: The incidence of post cataract surgery endophthalmitis has varied over the past century. [eyerounds.org]

Epidemiology Endogenous endophthalmitis can occur at any age and has no sexual predilection. [aafp.org]

Epidemiologic surveillance of postoperative endophthalmitis in a specialized ophthalmologic center in São Paulo, Brazil. Am J Infect Control. 2012;40(1):e1–3. 18. World Medical Association. [sboportal.org.br]

Pathophysiology Normally, the blood-ocular barrier prevents invasion from infective organisms but if this is breached (directly through trauma or indirectly due to a change in its permeability secondary to inflammation), infection can occur. [patient.info]

Pathophysiology Under normal circumstances, the blood-ocular barrier provides a natural resistance against invading organisms. [emedicine.medscape.com]

Multiple preventive measures are used to try to prevent infection after surgery. [cochranelibrary.com]

Preoperative prophylactic antibiotic usage may be considered as a preventive measure in sutureless vitrectomy. [ncbi.nlm.nih.gov]

ABSTRACT Acute endophthalmitis is a serious complication of cataract surgery that, given its infectious etiology, can be prevented using antiseptics and antibiotics. [200.98.68.239]