Presentation
If the result is positive, and it has been more than six months since the diagnosis, hepatitis B is still present and considered a chronic infection. [study.com]
In the 3 patients described here, HBV infection presented first and quickly resolved, with anti-HBs seroconversion. [academic.oup.com]
An open wound had been present approximately 4–6 weeks before her presentation. No other risk factor for an acute hepatitis virus infection was identified. [gastroenterologyandhepatology.net]
We present a case of acute hepatitis B fulfilling generally accepted criteria for dermatomyositis (DM). This simulation calls attention to another exclusion to be considered before diagnosing DM, and illustrates masking of liver disease by myopathy. [jamanetwork.com]
Thus, they started to present a serologic profile with anti-HBc antibody alone. [scielo.br]
Entire Body System
-
Rigor
After a rigorous screening of 653 HBsAg positive patients only 40 (6.12%) were found to have acute HBV infection. This is quite low in comparison to a report from China, where 182 of 507 (35.9%) were found to have acute HBV infection [ 20 ]. [journals.plos.org]
-
Hodgkin Lymphoma
Effectiveness of entecavir in the management of acute hepatitis B developing in a patient with Hodgkin's lymphoma: A case report. Scand J Infect Dis 2011;43:750-2. 33. De Socio GV, Mercuri A, Di Candilo F, Baldelli F. [ijmm.org]
Gastrointestinal
-
Nausea
She has flu-like symptoms such as nausea, fever, and weakness. She notices that her urine is darker than usual even though she has been trying to drink a lot of fluids. Cathy decides to see a doctor and gets her blood tested. [study.com]
The virus can provoke an acute illness characterised by nausea, malaise, abdominal pain, and jaundice but can also produce a chronic infection that is associated with an increased risk for chronic liver disease and hepatocellular carcinoma. [gov.uk]
Patients with severe nausea and/or vomiting may need to be hospitalized for treatment and intravenous fluids. Acute HBV is not treated with antiviral drugs. [medicinenet.com]
Some people may experience more severe symptoms such as nausea, vomiting, jaundice (yellowing of the eyes and skin), or a bloated stomach that may cause them to see a health care provider. [hepb.org]
Skin
-
Pruritus
Other symptoms in this stage include nausea, vomiting, and pruritus. From this point on, the clinical course may be highly variable. [medscape.com]
-
Photosensitivity
She denied fever, Raynaud's phenomenon, myalgia, morning stiffness, photosensitivity, and symptoms of polyserositis. She took no medication. Temperature and other vital signs were normal. [jamanetwork.com]
Neurologic
-
Personality Change
Encephalopathy due to a build-up of toxins in the brain, which causes confusion, drowsiness and personality changes, and eventually loss of consciousness or coma. [dermnetnz.org]
Treatment
The optimal pharmacological treatment of acute HBV infection remains controversial. [cochrane.org]
Most adults can rid the body of the virus without treatment. Infants, children, and adults with symptoms require treatment. Treatment is simple and usually does not require any medications. [study.com]
Treatment to Ameliorate Course of Acute Hepatitis B Treatment of Acute Asymptomatic Hepatitis B As with influenza virus infection, treatment could be used to ameliorate the course of disease rather to prevent chronic infection. [karger.com]
We report the P values for comparisons of treatment groups versus control. [ijmm.org]
What is the treatment for viral hepatitis? Treatment of acute viral hepatitis and chronic viral hepatitis are different. Treatment of acute viral hepatitis involves resting, relieving symptoms and maintaining adequate intake of fluids. [medicinenet.com]
Prognosis
What is the prognosis of viral hepatitis? The prognosis of viral hepatitis for most patients is good; however, this prognosis varies somewhat depending on the infecting virus. [medicinenet.com]
Prognosis deteriorates dramatically once hepatic encephalopathy sets in. [karger.com]
Thus, e antigen markers are more helpful in prognosis than in diagnosis. Chronic liver disease develops more often among patients with HBeAg and less often among patients with anti-HBe. [msdmanuals.com]
[…] cell proliferation Bridging necrosis Chronic viral hepatitis Formation of lymphoid follicles and mononuclear infiltrates Piecemeal necrosis : periportal liver cell necrosis with lymphocytic infiltration ; ; indicates chronic active hepatitis and poor prognosis [amboss.com]
Hepatitis may be sub-fulminant or fulminant, characterized by liver failure with a poor short-term vital prognosis, requiring urgent liver transplantation. [vhc-henrimondor.com]
Etiology
Definition, etiology, and review of 1,100 cases. Arch Intern Med. 1966;118:139-144. 2. Ropper AH, Wijdicks EFM, Truax BT. Guillain-Barré Syndrome. Philadelphia, Pa: FA Davis Company; 1991:57. 3. Plough IC, Ayerle RS. [gastroenterologyandhepatology.net]
The etiologic diagnosis of acute HBV infection was made on the basis of a high serum anti-HBc IgM titer. [academic.oup.com]
Etiologic considerations of fulminant non-A, non-B viral hepatitis in Japan: Analyses by nucleic acid amplification method. J Infect Dis 1998;178:325-33. [ PUBMED ] 10. [hepatitisbannual.org]
Hepatitis B virus: the major etiology of hepatocellular carcinoma. Cancer 1988; 61:1942-56. [ Links ] 3. Hoofnagle JH, Di Bisceglie A. Serologic diagnosis of acute and chronic hepatitis. Semin Liver Dis 1991; 2:3-83. [ Links ] 4. Andre F. [scielo.br]
Etiology Virus Transmission The frequency and patterns of transmission vary worldwide. [amboss.com]
Epidemiology
This molecular evidence indicates that heterosexual activity was the most likely transmission route of HBV B2 although this risk factor was not revealed by the field epidemiological study. [gut.bmj.com]
We used HAV as the reference to compare to the other hepatitis types and p Comparing epidemiology of AVH trends over time To describe the trends in the epidemiology of AVH over time, we compared the patient demographics, common risk factors, and proportions [bmcinfectdis.biomedcentral.com]
Hepatitis delta virus: epidemiology, natural course and treatment. J Infect Dis Ther. 2016 Mar 3. 4(271): [Full Text]. Khuroo MS, Kamili S, Khuroo MS. [medscape.com]
Epidemiological surveillance and reporting forms Surveillance of acute hepatitis B is essential to target prevention and control activities such as the selective immunisation programme. [gov.uk]
Pathophysiology
The hallmark of MGN’s pathophysiology is the collection of immune complexes within the basement membrane, which triggers a complement response. [gastroenterologyandhepatology.net]
Clinical Information Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test Hepatitis A: Hepatitis A virus (HAV) is an RNA virus that accounts for 20% to 25% of the viral hepatitis in United States adults [mayocliniclabs.com]
References: [5] [6] [7] [8] Pathophysiology Acute infection Hepatocytes infected by the hepatitis B virus express viral peptides on their surfaces lymphocytes recognize HBV -derived peptides and become activated ( CD8 cytotoxic T cells ) lymphocytes attack [amboss.com]
Prevention
But hepatitis B is completely preventable. All pregnant women in the U.S. are screened for hepatitis B, and if infected, appropriate steps can be taken to prevent mother-to-child transmission. [hhs.gov]
Advisory Committee on Immunization Practices (ACIP), Centers for Disease Control and Prevention (CDC). Update: Prevention of hepatitis A after exposure to hepatitis A virus and in international travelers. [medscape.com]
Immediate post-exposure vaccination is used to prevent infection, especially in babies born to infected mothers or following needle-stick injuries. 2. [gov.uk]
Conclusions Prevention and control strategies were effective in reducing the acute hepatitis B notification rate. However, stronger prevention and control measures are needed in adult risk groups, particularly MSM. Article metrics loading... [eurosurveillance.org]
These patients should be evaluated for liver transplantation and receive prophylaxis to prevent HBV reinfection as that would also prevent HDV reinfection. [karger.com]