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Acute Infectious Lymphocytosis


Presentation

  • Organized by body system, each section begins with a general framework covering clinical presentation, laboratory and diagnostic evaluation, and empirical antibiotic therapy.[books.google.com]
  • Case reports are presented of 5 cases of acute infectious lymphocytosis in siblings, ages 2¼-10 years. Symptoms included diarrhea, abdominal pain, vomiting, fever and cough. There was an absolute lymphocytosis lasting about three weeks.[bloodjournal.org]
  • An enterovirus, presently untyped, but resembling the Coxsackie A subgroup in physical, chemical and host specificity, was isolated in 21% of the patients' stool specimens.[nejm.org]
Fever
  • Symptoms included diarrhea, abdominal pain, vomiting, fever and cough. There was an absolute lymphocytosis lasting about three weeks. All of the cases had elevated eosinophil counts during the course of the disease.[bloodjournal.org]
  • Descriptive Epidemiology 587 Mechanisms and Routes of Transmission 7 Pathogenesis and Immunity 590 Patterns of Host Response 591 Control and Prevention 592 References 593 Suggested Reading 595 Rocky Mountain Spotted Fever Theodore E Woodward and J Stephen[books.google.com]
  • The differential diagnosis with various inf is carried out. the diseases (measles, a rubella, chicken pox, scarlet fever) which are followed by leukemoid tests (see. Leukemoid tests ) lymphoid type.[bigmed.info]
Down Syndrome
  • Syndrome 2 to 18 Years of Age924 924 LABORATORY VALUES911 Table 20 1989 Recommended Daily Dietary Allowance931 931 Interpretation of EBV Serology 932 932 Classic Clinical Findings in Disorders Characterized Parapneumonic Pleural Effusions 941 941 Causes[books.google.com]
  • syndrome Post-splenectomy Stress lymphocytosis The differential diagnosis of lymphocytopenia includes: Infections, acute General acute infections Tuberculosis Immunodeficiency AIDS Congenital defects of cellular immunity Cancer Immune Systemic lupus[pediatriceducation.org]
  • “But you can also see blasts in other things like transient abnormal myelopoiesis associated with Down syndrome,” she continued.[captodayonline.com]
Streptococcal Infection
  • Infections Barry M Gray 1 Introduction 673 Methodology 676 Biological Characteristics of the Organisms 684 Descriptive Epidemiology 688 Mechanisms and Routes of Transmission 694 Pathogenesis and Immunity 695 Patterns of Host Response 697 Control and[books.google.com]
  • However, acute streptococcal infections can lead to atypical lymphocytosis as well as elicit false positive viral antibody results. Atypical lymphocytes are shown here.[bestonlinemd.com]
Splenomegaly
  • An ultrasound study of 19 patients found that in 16 splenomegaly resolved in four weeks but in three it took eight weeks.[patient.info]
  • .  Splenomegaly is found in 50% of cases and hepatomegaly in approximately 10% of patients.  Rash is present in 20% of cases.  Complications are pneumonitis, meningoencephalitis, pericarditis, myocarditis, hepatitis, and laryngeal edema, all of which[slideshare.net]
  • There is almost never splenomegaly or lymphadenopathy. HTLV-1 may produce a transient lymphocytosis (usually 20.0 x10 9 /L) with fever,rash, and little lymphadenopathy. Most patients recover; however, some develop adult T cell leukemia.[med-ed.virginia.edu]
  • […] as tuberculosis[3] or brucellosis[3] Chronic lymphocytic leukemia Acute lymphoblastic leukemia Causes of relative lymphocytosis include: age less than 2 years; acute viral infections; connective tissue diseases, thyrotoxicosis, Addison's disease, and splenomegaly[enotes.tripod.com]
  • […] chronic lymphocytic leukemia acute lymphoblastic leukemia lymphoma post-splenectomy state smoking Causes of relative lymphocytosis include: age less than 2 years; acute viral infections; connective tissue diseases, thyrotoxicosis, Addison’s disease, and splenomegaly[bestonlinemd.com]
Pleural Effusion
  • Effusions 941 941 Causes of FalsePositive Dipstick Reactions for Table 73 Normal Ranges for Gonadotropin and Sex Steroid 947 Glasgow Coma Scale GCS for Adults and Children Table 97 Common Poisons and Antidotes955 955 Agerelated Prevalence of Principal[books.google.com]
  • Protracted fever, jaundice, pleural effusion, anemia, or the Guillain-Barre syndrome were dominant clinical findings among these patients.[hopkinsguides.com]
Abdominal Pain
  • Symptoms included diarrhea, abdominal pain, vomiting, fever and cough. There was an absolute lymphocytosis lasting about three weeks. All of the cases had elevated eosinophil counts during the course of the disease.[bloodjournal.org]
  • pains or the phenomena of a coloenteritis.[bigmed.info]
  • In pediatric ages up to 14 years old, acute infectious lymphocytosis is a clinical disorder, suspected to be of enterovirus-Coxsackie A subgroup that may have upper respiratory symptoms, fever, diarrhea and abdominal pain or a totally asymptomatic clinical[questdiagnostics.com]
  • . • Clinical Features:  Asymptomatic – patients with infectious lymphocytosis  Symptoms accompany the disease are fever, upper respiratory infection, diarrhea, and abdominal pain. 20.[slideshare.net]
  • Counsel patients to avoid traumatic activities, and seek evaluation for any significant abdominal pain, LUQ pain or L shoulder pain (referred from spleen, Kehr’s sign) that might represent splenic injury.[hopkinsguides.com]
Abdominal Pain
  • Symptoms included diarrhea, abdominal pain, vomiting, fever and cough. There was an absolute lymphocytosis lasting about three weeks. All of the cases had elevated eosinophil counts during the course of the disease.[bloodjournal.org]
  • pains or the phenomena of a coloenteritis.[bigmed.info]
  • In pediatric ages up to 14 years old, acute infectious lymphocytosis is a clinical disorder, suspected to be of enterovirus-Coxsackie A subgroup that may have upper respiratory symptoms, fever, diarrhea and abdominal pain or a totally asymptomatic clinical[questdiagnostics.com]
  • . • Clinical Features:  Asymptomatic – patients with infectious lymphocytosis  Symptoms accompany the disease are fever, upper respiratory infection, diarrhea, and abdominal pain. 20.[slideshare.net]
  • Counsel patients to avoid traumatic activities, and seek evaluation for any significant abdominal pain, LUQ pain or L shoulder pain (referred from spleen, Kehr’s sign) that might represent splenic injury.[hopkinsguides.com]
Nausea
  • Nausea and anorexia. Arthralgias and myalgias occur but are less common than in other viral infectious diseases and are rarely severe. Other symptoms include cough, chest pain and photophobia.[patient.info]
Vomiting
  • Symptoms included diarrhea, abdominal pain, vomiting, fever and cough. There was an absolute lymphocytosis lasting about three weeks. All of the cases had elevated eosinophil counts during the course of the disease.[bloodjournal.org]
Vomiting
  • Symptoms included diarrhea, abdominal pain, vomiting, fever and cough. There was an absolute lymphocytosis lasting about three weeks. All of the cases had elevated eosinophil counts during the course of the disease.[bloodjournal.org]
Thrombosis
  • Dormans 584585 585 Otitis MediaWilliam R Graessle 592593 592 Pulmonary Embolism Akinyemi 0 Ajayi 678679 678 Pyelonephritis Kevin F C Meyers684685 684 Rectal Prolapse Andrew E Mulberg 690691 690 Renal FailureAcute Seth L Schulman 696697 696 Renal Wenous Thrombosis[books.google.com]
  • An underlying systemic disease is much more common in reactive thrombocytosis, while ischemia, thrombosis, and bleeding complications are more characteristic of clonal thrombocytosis. “That’s why you have to identify these patients,” she said.[captodayonline.com]
Dermatitis
  • 702703 702 Retropharyngeal Abscess Richard M Rutstein 708709 708 Rhabdomyosarcoma Kara M Kelly714715 715 Rickettsial Disease Joel A Fein 722723 722 Salmonella Infections Kevin C Osterhoudt728729 728 Scarlet Fever Mark L Bagarazzi 734735 734 Seborrheic Dermatitis[books.google.com]
  • Eosinophilia ( 0.35 X 10 9 /L ) is associated with many forms of immunologic damage and can, interestingly, inactivate IgE mediated reactions (immediate hypersensitivity). allergic disorders -asthma, seasonal rhinitis, eczema, atopic dermatosis, pemphigus and dermatitis[med-ed.virginia.edu]
  • García-Silva J, Almagro M, Peña C, et al: CD4 T-lymphocytopenia, Kaposi’s sarcoma, HHV-8 infection, severe seborrheic dermatitis, and onychomycosis in a homosexual man without HIV infection [letter]. Int J Dermatol 38:231, 1999. 165.[medtextfree.wordpress.com]
Exanthema
  • Clinical findings, which include acute fever symptoms, enlarged lymph nodes, and sometimes exanthema, help to identify a lymphatic reactive state. Unlike the case in acute leukemias, erythrocyte and thrombocyte counts are not significantly reduced.[mussenhealth.us]
  • […] infectious mononucleosis secondary to Epstein-Barr virus Lymphadenopathy 95 88.9 57 95 89.5 Fever 30 79 45 92.3 79.7 General body pain NR NR 77 NR 69.3 Pharyngitis 100 95 73 83.5 55.2 Hepatomegaly 25 36.7 7 58.1 47.2 Splenomegaly 35 53.3 8 47.4 36.8 Exanthema[bmcresnotes.biomedcentral.com]
Fear
  • She provides a window into these women's lives, brilliantly portraying their hopes and fears and their struggle to live with dignity.[books.google.com]
  • C omplications of Leukopenia The most feared complication of leukopenia is suppression of the neutrophil cell line and subsequent neutropenia.[antimicrobe.org]
Epistaxis
  • Disease in Newborns Robert M Cohn536537 536 Milia Albert C Yan 542543 543 Muscular Dystrophies Olafur Thorarensen 550551 550 Near Drowning Kathy N Shaw556557 556 Neonatal Apnea Daniel H Conway 564565 564 Neuroblastoma Julie W Stern 570571 571 Nosebleeds Epistaxis[books.google.com]
Stroke
  • […] all the latest approaches in clinical laboratory medicine with new and updated coverage of: the chemical basis for analyte assays and common interferences; lipids and dyslipoproteinemia; markers in the blood for cardiac injury evaluation and related stroke[books.google.com]

Workup

  • “It’s important to exclude pseudothrombocytopenia and pseudoneutropenia before you undertake additional workups.[captodayonline.com]
Lymphocytes Increased
  • Lymphocytosis A condition in which the number of lymphocytes increases above normal levels. lym·pho·cy·to·sis ( lim'fō-sī-tō'sis ) A form of leukocytosis in which there is an actual or relative increase in the number of lymphocytes.[medical-dictionary.thefreedictionary.com]
  • Patients with acute or chronic leukemia may also have an occurrence of atypical lymphocyte increase.[bestonlinemd.com]
  • Lymphocytes increase in many viral infections and with tuberculosis. A common reason for significant lymphocytosis is lymphocytic leukemia. The majority of both acute and chronic forms of leukemia affect lymphocytes.[rnceus.com]
Pleural Effusion
  • Effusions 941 941 Causes of FalsePositive Dipstick Reactions for Table 73 Normal Ranges for Gonadotropin and Sex Steroid 947 Glasgow Coma Scale GCS for Adults and Children Table 97 Common Poisons and Antidotes955 955 Agerelated Prevalence of Principal[books.google.com]
  • Protracted fever, jaundice, pleural effusion, anemia, or the Guillain-Barre syndrome were dominant clinical findings among these patients.[hopkinsguides.com]

Treatment

  • More treatment-centered approach helps you focus on the therapeutic process—from diagnostic evaluation and testing to treatment selection.[books.google.com]
  • Treatment the Bed rest, symptomatic means desensibilizing drugs, vitamins; antibiotics are shown at emergence of signs of consecutive infection. Current and forecast favorable. A wedge, manifestations stick to 4 — 5 days, 10 — 14 is more rare.[bigmed.info]
  • Treatment is primarily supportive, with rest during the acute stage of illness and symptomatic care.[hawaii.edu]

Prognosis

  • Prognosis Usually asymptomatic or of short duration and self-limiting.[patient.info]
  • Pneumonia, pyelonephritis, cellulitis, soft tissue infection, bacteremia, sepsis, meningitis, or endocarditis is all associated with neutrophilia, and, indeed, patients who fail to mount a significant leukocyte response to pyogenic infection have a worse prognosis[antimicrobe.org]

Etiology

  • The search for an etiology of the disease included infectious and noninfectious agents. Examinations of stools for parasites, cultures of throat and stool for bacteria, and cultures of throat, stool and blood for viruses were done.[nejm.org]
  • The etiology and a pathogeny Consider that a disease-producing factor is the lymphotropic virus, to-ry through a mucous membrane of a nasal part of a throat or went. - kish. a path with current of a lymph gets to the next limf, nodes and it is localized[bigmed.info]
  • M iscellaneous Etiologies of Neutropenia Selected etiologies of neutropenia are noted in Table 4. The clinician should approach leukopenia by one of the mechanisms noted in the above section.[antimicrobe.org]
  • Myelodysplasia (mechanism uncertain) Immune mediated phenomenon (autoimmune haemolytic anaemia and immune thrombocytopenia) Rare causes: thrombotic thrombocytopenic purpura, bone marrow necrosis Haematological malignancies with viral etiology EBV is etiologically[fmshk.com.hk]
  • Moore Acute infectious lymphocytosis: an etiologic and epidemiologic study of an outbreak [8.] F.K. Nkrumah, P.A. Addy Acute infectious lymphocytosis Lancet, 1 (1973), pp. 1257-1258 [9.] B.K. Mandal, K.J.[analesdepediatria.org]

Epidemiology

  • Descriptive Epidemiology 587 Mechanisms and Routes of Transmission 7 Pathogenesis and Immunity 590 Patterns of Host Response 591 Control and Prevention 592 References 593 Suggested Reading 595 Rocky Mountain Spotted Fever Theodore E Woodward and J Stephen[books.google.com]
  • Epidemiology the Source of a contagium are sick children, and also children with the erased and asymptomatic forms of a disease. L. lake and. meets everywhere and it is characterized by the expressed contageousness.[bigmed.info]
  • Annals of epidemiology. 6 (4): 299–306. doi : 10.1016/s1047-2797(96)00024-5. PMID 8876840. For example, if the total WBC count is 30,000, and the %lymphocytes is 30, the absolute lymphocyte count is 9,000 per microliter. External links [ edit ][en.wikipedia.org]
  • Moore Acute infectious lymphocytosis: an etiologic and epidemiologic study of an outbreak [8.] F.K. Nkrumah, P.A. Addy Acute infectious lymphocytosis Lancet, 1 (1973), pp. 1257-1258 [9.] B.K. Mandal, K.J.[analesdepediatria.org]
Sex distribution
Age distribution

Pathophysiology

  • The reactive, or secondary, lymphocytoses are conditions that involve absolute increases in lymphocytes caused by physiologic or pathophysiologic responses to infection, inflammation, toxins, cytokines, or unknown agents.[doctorslounge.com]
  • Biological abnormality Pathophysiology Pancytopenia Phagocytosis of blood cells and precursors.[fmshk.com.hk]
  • Absolute Lymphocytosis with Variant Lymphocyte Morphology • Pathophysiology:  The virus is found in urine, oral and cervical secretions, and semen, as well as in leukocytes.  Transmission in adults is primarily venereal.  More than half of adults possess[slideshare.net]
  • […] ultimately will develop monoclonal B-cell lymphoma or B-cell leukemia.38,39 SECONDARY (REACTIVE) LYMPHOCYTOSIS Secondary lymphocytosis defines conditions associated with an increase in the absolute number of lymphocytes secondary to a physiologic or pathophysiologic[medtextfree.wordpress.com]

Prevention

  • Descriptive Epidemiology 587 Mechanisms and Routes of Transmission 7 Pathogenesis and Immunity 590 Patterns of Host Response 591 Control and Prevention 592 References 593 Suggested Reading 595 Rocky Mountain Spotted Fever Theodore E Woodward and J Stephen[books.google.com]
  • Author Affiliations * From the National Communicable Disease Center, Bureau of Disease Prevention and Environmental Control, Public Health Service, United States Department of Health, Education, and Welfare, Atlanta, Ga.[nejm.org]
  • Prevention: isolation of the patient, carrying out current disinfection (see); for the children who were in contact with the patient establish observation, at them investigate blood. Bibliography: Kassirsky I. A. and Alekseev G. A.[bigmed.info]
  • Health care services aimed at preventing health problems or maintaining health are provided. 9. Patient-focused care is provided by working with health care professionals, including those from other disciplines. Medical Knowledge 10.[pediatriceducation.org]

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