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Acute Juvenile Hemorrhagic Cystitis


Presentation

  • Designed specifically with physicians, pharmacologists, and other members of the health care delivery team in mind, the CRC Desk Reference of Clinical Pharmacology features more than 2,000 entries appearing in three formats: Short reviews: these present[books.google.com]
  • […] monozygotic twins with distinct presentation pathology and outcome: Is it familial or in utero metastasis Abu-Arja R, Hashem H, El-Sheikh A, Abusin G., Pediatric Blood and Cancer, 12/2013 Neuroblastoma in Monozygotic Twins - Distinct Presentation, Pathology[doximity.com]
  • Because SLE can present with a number of signs and symptoms, the diagnosis often is considered in children who have prolonged unexplained complaints. Epidemiology Approximately 20% of all patients who have SLE are diagnosed in childhood.[pedsinreview.aappublications.org]
  • It is indicated, if the adverse prognostic factors of the acute myeloblastic leukemia (brain damage, a very high white blood cell count) are present.[bookinghealth.com]
  • HSV presents as a unilateral recurrent anterior uveitis or iridocyclitis in 85% of cases.[ophthalmologymanagement.com]
Physician
  • Designed specifically with physicians, pharmacologists, and other members of the health care delivery team in mind, the CRC Desk Reference of Clinical Pharmacology features more than 2,000 entries appearing in three formats: Short reviews: these present[books.google.com]
  • *Medscape Business of Medicine Academy Survey, September 2015 Learn from Experienced Professionals Courses were developed especially for physicians by business health experts and experienced physicians.[medscape.org]
  • Physicians, Nurse Practitioners and PAs, already on Doximity.[doximity.com]
  • A physician can differentiate most perinatal infections from infections due to sexual abuse. Some infections, such as those from chlamydia or warts, are more difficult to differentiate.[childabusemd.com]
  • LINDSAY, LT COL, USAF, MC, Saint Louis University Family Medicine Residency Program, Belleville, Illinois Am Fam Physician. 2009 Oct 1;80(7):697-704.[aafp.org]
Neglect
  • Cincinnati Children's Hospital Diagnosis and Treatment reference materials; 2003 and American Academy of Pediatrics Committee on Child Abuse and Neglect. Guidelines for the evaluation of sexual abuse of children (RE9202).[childabusemd.com]
Hematuria
  • "Hematuria." 5-Minute Clinical Consult, 27th ed., Wolters Kluwer, 2019. 5minute, www.unboundmedicine.com/5minute/view/5-Minute-Clinical-Consult/116258/all/Hematuria. Hematuria.[unboundmedicine.com]
  • In addition to hemorrhagic cystitis, temporary hematuria can also be seen in bladder infection or in children as a result of viral infection.[en.wikipedia.org]
  • Arteritis with Kidney Involvement Gestational Hypertension Gitelman Syndrome Glomerular Diseases Glomerular Tubular Reflux Glycosuria Goodpasture Syndrome Hair Dye Ingestion and Acute Kidney Injury Hantavirus Infection Podocytopathy Heat Stress Nephropathy Hematuria[thekaiganfoundation.com]
  • A 30, 31 In patients with a normal initial urinalysis or with isolated hematuria, a monthly urinalysis should be continued for six months to detect signs of renal involvement.[aafp.org]
  • Reflux Glycosuria Goodpasture Syndrome Green Smoothie Cleanse Nephropathy HANAC Syndrome Harvoni (Ledipasvir with Sofosbuvir)-Induced Renal Injury Hair Dye Ingestion and Acute Kidney Injury Hantavirus Infection Podocytopathy Heat Stress Nephropathy Hematuria[kidney.nyc]
Dysuria
  • Hemorrhagic cystitis or haemorrhagic cystitis is an inflammation of the bladder defined by lower urinary tract symptoms that include dysuria, hematuria, and hemorrhage.[en.wikipedia.org]
  • These symptoms include pain on urination (dysuria), feeling of incomplete voiding, cloudy urine, uncomfortable lower abdomen and frequent urination (polyuria), without fever. If there is a fever, acute pyelonephritis should be suspected.[koreaherald.com]
  • Bilharziasis (Schistosomiasis) of the urinary bladder This patient presented with lower urinary symptoms, dysuria and hematuria.[slideshare.net]
  • […] vitiligo, poliosis, tick/insect bites Neurologic—tinnitus, headache, meningism, paresthesias, weakness/paralysis Respiratory—shortness of breath, cough, sputum production Gastrointestinal (GI)—diarrhea, bloody stools, oral aphthous ulcers Genitourinary (GU—dysuria[medtextfree.wordpress.com]
  • […] well encapsulated renal mass - papillary renal cell carcinoma, solid variant Case 43: 44 year old man with a 1 mm incidental renal mass at nephrectomy - papillary adenoma Case 40: 56 year old man with B cell CLL, post-treatment for a relapse, now with dysuria[pathologyoutlines.com]
Urinary Urgency
  • Interstitial cystitis (bladder pain syndrome, Hunner ulcer) is a painful bladder disease characterized by chronic urinary urgency, frequency, and pain without evidence of bacterial infection.[slideshare.net]

Workup

  • Mammography The preoperative workup also should include a mammogram for women older than 35 years who have not had one in the preceding 6-12 months.[www1.cgmh.org.tw]
  • Clinical Presentation All patients with suspected NSOI require a full ophthalmic assessment/workup. NSOI is typically characterized by the abrupt onset of pain, proptosis and other inflammatory signs such as swelling and erythema.[eyewiki.aao.org]
Pyuria
  • Bladder content is heterogeneous with presence of liquid level suggestive of pyuria (arrow).[slideshare.net]
Staphylococcus Aureus
  • Henoch-Schönlein purpura associated with methicillin-resistant Staphylococcus aureus infection. Am J Med. 2006;119(1):85-86. 15. Yang YH, Chuang YH, Wang LC, Huang HY, Gershwin ME, Chiang BL. The immunobiology of Henoch-Schönlein purpura.[aafp.org]
  • Urine cultures revealed polymicrobial infection including Staphylococcus aureus and multiresistant extended-spectrum beta-lactamase (ESBL)-positive Escherichia coli Active infectious cystitis in a 52-year- old woman with poorly controlled diabetes, dehydration[slideshare.net]
Rickettsia Rickettsii
  • rickettsii, CBC, electrolytes Thrombocytopenic purpura Thrombocytopenia associated with petechia or purpura; bleeding (e.g., gingival, gastrointestinal, mucocutaneous); symptoms of end-organ ischemia (in patients with thrombotic disease) CBC with peripheral[aafp.org]

Treatment

  • Chemotherapy is the basic treatment method.[bookinghealth.com]
  • Prednisolone treatment Prednisolone treatment over a longer period of time leads to increased appetite and weight, both during and after concluded treatment.[oncolex.org]
  • Nonalkylating agent immunomodulatory drugs likely do not increase cancer risk to a degree that outweighs the benefits of treatment. 16 CONCLUSION Steroids are still the first-line treatment for the treatment of noninfectious uveitis.[retinalphysician.com]
  • As a result its use should probably be limited to those who have failed virtually all other available treatments. [90] Surgical Therapy Surgical resection can be an effective form of treatment in NSOI refractory to treatment.[eyewiki.aao.org]
  • Treatment [ edit ] Unfortunately mesna is ineffective as a treatment once hemorrhagic cystitis has developed.[en.wikipedia.org]

Prognosis

  • Long-term prognosis depends on the severity of renal involvement. End-stage renal disease occurs in 1 to 5 percent of patients. Henoch-Schönlein purpura is an acute, systemic, immune complex-mediated, leukocytoclastic vasculitis.[aafp.org]
  • Daclizumab has been reported to be effective in the treatment of refractory uveitis and has been generally welltolerated.14 Prognosis and Complications Acute episodes of inflammation may be self-limited and benign or may cause complications such as anterior[ophthalmologymanagement.com]
  • Table 4 summarizes clinical presentation, laboratory investigations, therapies, and prognosis. Table 4. Idiopathic inflammatory myopathies (IIM), Summary.[frontiersin.org]
  • It is a distinct disease entity in young children with Down's syndrome where the prognosis is good.[oncolex.org]
  • Young males have the worst prognosis with significantly more frequent neurological, ocular and vascular involvement. BD treatment is aimed at alleviating inflammation.[ped-rheum.biomedcentral.com]

Etiology

  • Epidemiologic, twin, and human leukocyte antigen data suggest a strong genetic contribution to the etiology of SLE, but the exact cause is unknown.[pedsinreview.aappublications.org]
  • Description Gross (visible) or microscopic (nonvisible) blood in the urine, either symptomatic or asymptomatic Epidemiology Prevalence Children: gross: 0.13%; asymptomatic microscopic hematuria (AMH): 0.4–4.1% Adults: AMH: 0.9–17%, depending on population Etiology[unboundmedicine.com]
  • Pathophysiology: Two theories exist as to the etiology of sex cord騯tromal tumors. The first proposes that these neoplasms are derived from the mesenchyme of the developing genital ridge.[www1.cgmh.org.tw]
  • Pathophysiology The etiology and pathogenesis of NSOI is currently unknown. Both infectious and immune-mediate etiologies have been implicated.[eyewiki.aao.org]
  • A possible decline in the incidence and severity of Behçet’s disease: implications for an infectious etiology and oral health. Clin Exp Rheumatol. 2010;28(4 Suppl 60):S86–90.[ped-rheum.biomedcentral.com]

Epidemiology

  • Epidemiologic, twin, and human leukocyte antigen data suggest a strong genetic contribution to the etiology of SLE, but the exact cause is unknown.[pedsinreview.aappublications.org]
  • Epidemiological characteristics of uveitis in Switzerland. Int Ophthalmol. 1994;18:293-298. 5. Vadot E, Barth E, Billet P. Epidemiology of uveitis: preliminary results of a prospective study in the Savoy. In: Saari KM, ed. Uveitis Update.[ophthalmologymanagement.com]
  • Explore these free sample topics: -- The first section of this topic is shown below -- Basics Description Gross (visible) or microscopic (nonvisible) blood in the urine, either symptomatic or asymptomatic Epidemiology Prevalence Children: gross: 0.13%[unboundmedicine.com]
  • Henoch-Schönlein purpura in childhood: epidemiological and clinical analysis of 150 cases over a 5-year period and a review of the literature. Semin Arthritis Rheum. 2005;35(3):143-153. 4. Saulsbury FT. Epidemiology of Henoch Schönlein purpura.[aafp.org]
  • Epidemiology The geographic distribution of BD is spread along the former Silk Road from the Far East to the Mediterranean basin.[ped-rheum.biomedcentral.com]
Sex distribution
Age distribution

Pathophysiology

  • […] visible) or microscopic (nonvisible) blood in the urine, either symptomatic or asymptomatic Epidemiology Prevalence Children: gross: 0.13%; asymptomatic microscopic hematuria (AMH): 0.4–4.1% Adults: AMH: 0.9–17%, depending on population Etiology and Pathophysiology[unboundmedicine.com]
  • Pathophysiology The etiology and pathogenesis of NSOI is currently unknown. Both infectious and immune-mediate etiologies have been implicated.[eyewiki.aao.org]
  • Pathophysiology: Two theories exist as to the etiology of sex cord騯tromal tumors. The first proposes that these neoplasms are derived from the mesenchyme of the developing genital ridge.[www1.cgmh.org.tw]
  • […] in infants and children younger than two years. 6 It is more severe and more likely to cause long-term renal disease in adults. 7, 8 Henoch-Schönlein purpura is the most common vasculitis in children and has a slight predominance in males. 3 - 5, 9 Pathophysiology[aafp.org]
  • Myositis specific autoantibodies: changing insights in pathophysiology and clinical associations. Curr Opin Rheumatol (2004) 16 (6):692–9. PubMed Abstract Google Scholar 55. Miller T, Al-Lozi M, Lopate G, Pestronk A.[frontiersin.org]

Prevention

  • It includes the following aspects: Prevention of complications that may occur as a result of treatment. It can be pneumonia, lymphostasis, thromboembolic or infectious complications. Restoration of general health.[bookinghealth.com]
  • Long-term therapy prevents relapse of uveitis in approximately 70% of patients with recurrent non-granulomatous anterior uveitis. Immunomodulatory therapy.[ophthalmologymanagement.com]
  • Incidence and prevention of bladder toxicity from cyclophosphamide in the treatment of rheumatic diseases: a data-driven review. Arthritis Rheum 2010;62:9-21. PMID: 20039416.[rheumaknowledgy.com]
  • & Victims of Terrorism Gold Ribbon : Alveolar Rhabdomyosarcoma, Childhood Cancer, COPD, Embryonal Rhabdomyosarcoma, Neuroblastoma and Osteosarcoma (alternate yellow) Black Ribbon : Accidents, Amish Support, Anti-Terrorism, Gang Prevention, Gun Control[ribbonsforareason.com]
  • Mesna is given to prevent hemorrhagic cystitis. A urine test should be taken once a day. With high-dose cytarabine, prednisolone eye drops are given to prevent chemical conjunctivitis during and for 2 days after a treatment.[oncolex.org]

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