This presentation is not the classic description of TRALI. Our patient improved with supportive treatment and was successfully extubated on postoperative day 4. [ncbi.nlm.nih.gov]

• Bronchospasm and Wheezing

  Allergic and anaphylactic transfusion reactions may manifest as hypotension and respiratory distress but are marked by laryngeal edema or bronchospasm with wheezing and a normal CXR. [professionaleducation.blood.ca]

• Right Upper Quadrant Tenderness

  He was hypotensive, jaundiced and had right upper quadrant tenderness. Laboratory testing showed a leucocytosis, elevated liver function tests, total bilirubin and International Normalised Ratio (INR). [ncbi.nlm.nih.gov]

• Diplopia

  A 79-year-old woman with an 18-month history of myasthenia gravis, was treated with a 4-day course of plasma exchange for symptomatic control of ptosis, diplopia, generalized fatigue, and chewing difficulties. [ncbi.nlm.nih.gov]

She was managed as TRALI after diagnostic workup and transported to the intensive care unit. In the following days her clinical status changed dramatically with complete recovery. [ncbi.nlm.nih.gov]

• HLA-A2

  RESULTS: Anti-HLA-A2 antibodies significantly increased PMN activation, with subsequent endothelial dysfunction. [ncbi.nlm.nih.gov]

In vitro, MH-S cells were infected with H9N2 influenza virus with or without kaempferol treatment. [ncbi.nlm.nih.gov]

Treatment and prognosis It tends to be self-limiting and treatment is supportive, with a prognosis substantially better than most causes of clinical acute lung injury. transfusion-associated circulatory overload (TACO) Promoted articles (advertising) [radiopaedia.org]

Abstract Patients with aortic dissection (AD) may present acute lung injury (ALI) that may affect the prognosis. In this study, we aim to investigate the roles and mechanism of IL-22 in the pathogenesis of AD complicated with ALI. [ncbi.nlm.nih.gov]

CONCLUSIONS: In the absence of any other known etiology, multiple defibrillation shocks may have played a role in the genesis of ALI in our patient, but this remains speculative. [ncbi.nlm.nih.gov]

Etiology and outcomes of pulmonary and extrapulmonary acute lung injury/ARDS in a respiratory ICU in North India. Chest 2006;130:724-9. [ PUBMED ] [ FULLTEXT ] 12. Hudson LD, Milberg JA, Anardi D, Maunder RJ. [dx.doi.org]

The etiology of TRALI may be attributable to the presence of anti-HLA and/ or anti-granulocyte antibodies in the plasma of multiparous females or donors who have received previous transfusions. [fda.gov]

Since reliable data on its epidemiology in Brazil are not available, the difficulty to diagnose, varied clinical presentation, and absence of specific laboratory data, case reports are important. [ncbi.nlm.nih.gov]

If there is no prognostic or epidemiological difference between ALI and ARDS patients, then the two categories should be combined. [thorax.bmj.com]

However, these frequencies are higher than those found in national epidemiological studies conducted in the cities of Porto Alegre and São Paulo. (18-19) Comparison with other epidemiological studies is difficult due to methodological differences and, [scielo.br]

We have investigated aspects of ALI/ARDS varying from epidemiology to predictive and prognostic biomarkers and genetic polymorphisms to treatment interventions. [medicine.emory.edu]

The history, pathophysiology, and treatment of TRALI are discussed. Potential preventive measures are reviewed. [ncbi.nlm.nih.gov]

To identify biomarkers of the pathophysiological changes associated with the syndrome (i.e., alveolocapillary hyperpermeability, DAD, pulmonary hypertension, fibrosis) based on miRNAs sequencing. [ciberes.org]

In the present review, we will describe the pathophysiological aspects of acute lung injury induced by combined burn and smoke inhalation and examine various therapeutic approaches. acute lung injury burn and smoke inhalation cytokine nitric oxide (NO [clinsci.org]

Prevention of TRALI represents a complex challenge. There is no single intervention that will prevent every case of TRALI, but several interventions have been proposed to reduce the risk. [ncbi.nlm.nih.gov]