Presentation
This presentation is not the classic description of TRALI. Our patient improved with supportive treatment and was successfully extubated on postoperative day 4. [ncbi.nlm.nih.gov]
Eyes
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Diplopia
A 79-year-old woman with an 18-month history of myasthenia gravis, was treated with a 4-day course of plasma exchange for symptomatic control of ptosis, diplopia, generalized fatigue, and chewing difficulties. [ncbi.nlm.nih.gov]
Neurologic
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Rabies
Mahadeo KM 1, McArthur J 2, Adams RH 3, Radhi M 4, Angelo J 5, Jeyapalan A 6, Nicol K 7, Su L 8, Rabi H 9, Auletta JJ 10, Pai V 11, Duncan CN 12, Tamburro R 13, Dvorak CC 14, Bajwa RPS 15. [ncbi.nlm.nih.gov]
Urogenital
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Cesarean Section
Congenital hypofibrinogenemia may be responsible for the development of subfascial hematoma, a complication of cesarean section, necessitating relaparotomy. [ncbi.nlm.nih.gov]
Workup
She was managed as TRALI after diagnostic workup and transported to the intensive care unit. In the following days her clinical status changed dramatically with complete recovery. [ncbi.nlm.nih.gov]
HLA Type
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HLA-A2
RESULTS: Anti-HLA-A2 antibodies significantly increased PMN activation, with subsequent endothelial dysfunction. [ncbi.nlm.nih.gov]
Treatment
KEYWORDS: ALI; MSC treatment; mesenchymal stromal/stem cells [ncbi.nlm.nih.gov]
Prognosis
Treatment and prognosis It tends to be self-limiting and treatment is supportive, with a prognosis substantially better than most causes of clinical acute lung injury. transfusion-associated circulatory overload (TACO) Promoted articles (advertising) [radiopaedia.org]
Since prognosis can be excellent, identification and emergent management is essential, particularly in patients with comorbid neurological disease. [ncbi.nlm.nih.gov]
Etiology
CONCLUSIONS: In the absence of any other known etiology, multiple defibrillation shocks may have played a role in the genesis of ALI in our patient, but this remains speculative. [ncbi.nlm.nih.gov]
Martínez-Salazar,Alberto Tobón-Castaño Infectio. 2014; 18(3): 120 4 Etiology and Outcomes of ARDS in a Rural-Urban Fringe Hospital of South India Tarun George,Stalin Viswanathan,Ali Hasan Faiz Karnam,Georgi Abraham Critical Care Research and Practice. [dx.doi.org]
The etiology of TRALI may be attributable to the presence of anti-HLA and/ or anti-granulocyte antibodies in the plasma of multiparous females or donors who have received previous transfusions. [fda.gov]
Epidemiology
Since reliable data on its epidemiology in Brazil are not available, the difficulty to diagnose, varied clinical presentation, and absence of specific laboratory data, case reports are important. [ncbi.nlm.nih.gov]
If there is no prognostic or epidemiological difference between ALI and ARDS patients, then the two categories should be combined. [thorax.bmj.com]
However, these frequencies are higher than those found in national epidemiological studies conducted in the cities of Porto Alegre and São Paulo. (18-19) Comparison with other epidemiological studies is difficult due to methodological differences and, [scielo.br]
We have investigated aspects of ALI/ARDS varying from epidemiology to predictive and prognostic biomarkers and genetic polymorphisms to treatment interventions. [medicine.emory.edu]
Pathophysiology
The history, pathophysiology, and treatment of TRALI are discussed. Potential preventive measures are reviewed. [ncbi.nlm.nih.gov]
Prevention
Prevention of TRALI represents a complex challenge. There is no single intervention that will prevent every case of TRALI, but several interventions have been proposed to reduce the risk. [ncbi.nlm.nih.gov]