This article summarizes our current understanding of the relationship between dysregulation of the complement system and glomerular inflammation. [ncbi.nlm.nih.gov]

In our view, this classification would alert the pathologist and nephrologist to the importance of screening for acquired and genetic abnormalities in complement regulation. [ncbi.nlm.nih.gov]

A pathologist examines the biopsy under a microscope. After putting together clinical findings, special studies on tissues (if needed) and with microscope findings, the pathologist arrives at a definitive diagnosis. [dovemed.com]

Members save 5.00 USD or more Item Details: Intended Audience: Pathologists, Residents, Clinical Scientists, Laboratory Technologist/Scientist (Includes all sub-specialty areas), Students, Pathologist Assistants, Laboratory Directors and Educators Upon [ascp.org]

[…] recently published cohort data highlight crucial aspects of this group of diseases and support the need for extensive genetic and biomarker research to validate the pathologic mechanisms, delineate the spectrum of disease and guide the design of the rigorous [ncbi.nlm.nih.gov]

These retinal lesions can be associated with choroidal neovascularization and central serous chorioretinopathy (CSCR). [ncbi.nlm.nih.gov]

CONCLUSIONS: We provide new insights into the pathogenesis of Ig-MPGN/C3G that underscore the complex nature of these diseases and suggest that the current C3G classification may miss many cases associated with abnormalities of the complement alternative [ncbi.nlm.nih.gov]

Proteinuria relapsed when eculizumab was withdrawn, but the re-introduction of eculizumab normalized proteinuria. [ncbi.nlm.nih.gov]

RESULTS: Eighty-two patients (90%) exhibited microscopic hematuria; 51 (62%), exhibited only microscopic hematuria, whereas the remaining 31 additionally had proteinuria (38%); 28 proteinuric patients developed chronic renal failure (CRF). [ncbi.nlm.nih.gov]

It is a benign condition that causes persistent microscopic hematuria. [en.wikipedia.org]

12 who identified two families in Cyprus with autosomal-dominant microscopic hematuria whose renal biopsy turned up a C3G with lesions different from MPGN. [revistanefrologia.com]

Vernon KA et al (2011) [ 12 ] CFHR5 nephropathy 1 1 1 1 Right after the transplantation, persistent microscopic hematuria was observed. There is no established treatment for C3GP. [rrtjournal.biomedcentral.com]

Cryopyrin-associated periodic syndromes (CAPS) are autoinflammatory diseases comprising three clinically overlapping disorders: familial cold urticarial syndrome (FCAS), Muckle-Wells syndrome (MWS), and neonatal-onset multisystem inflammatory disease [ncbi.nlm.nih.gov]