Presentation
We found also that fibrin degradation products were present in high concentrations in the urine of patients with post-streptococcal nephritis, again an unexpected finding. [ncbi.nlm.nih.gov]
[…] g was presented on day 38 of life with sudden onset of irritability, inconsolable crying and mild edema. [semanticscholar.org]
Approximately 15% of patients with allergic interstitial nephritis present with a maculopapular rash. Many patients are asymptomatic. E. What diagnostic tests should be performed? AIN may present with a maculopapular rash. 1. [clinicaladvisor.com]
Glomerulonephritis can present with different clinical syndromes. These include nephrotic and nephritic syndrome. Glomerulonephritis is discussed in more detail in the separate Glomerulonephritis article. [patient.info]
Entire Body System
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Leg Edema
Symptoms of acute nephritic syndrome include: Edema in the face and legs: Edema is the accumulation of fluids in the body, usually under the skin, leading to a puffy appearance. [ada.com]
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Leg Swelling
Treatment usually focuses on reducing high cholesterol, blood pressure, leg swelling and protein in urine – through diet and medication. [kidneycareuk.org]
Respiratoric
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Pertussis
Other causes of this kidney problem involve parasitic infections such as toxoplasmosis or malaria, anything that can cause glomerulonephritis, primary glomerular diseases, Guillain-Barré syndrome, some multi-systemic diseases or even diphtheria-pertussis-tetanus [ic.steadyhealth.com]
Diphtheria-pertussis-tetanus vaccine Management In primary care Take a history - ask about onset of symptoms and uraemic symptoms; look for a clue to an underlying cause - eg, recent streptococcal infection, other infection, multisystem disease. [patient.info]
Miscellaneous noninfectious causes of acute GN include the following: Guillain-Barré syndrome Irradiation of Wilms tumor Diphtheria-pertussis-tetanus (DPT) vaccine Serum sickness Epidermal growth factor receptor activation, [10] and possibly its inhibition [emedicine.medscape.com]
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Sputum
Membranoproliferative nephritis (type of kidney inflammation) Postinfectious GN (GN that results after an infection) Signs & Symptoms of Acute Glomerulonephritis (AGN) Patients who have secondary causes of AGN often exhibit these symptoms: Cough with blood-tinged sputum [healthcommunities.com]
Eyes
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Blurred Vision
vision, usually from burst blood vessels in the retina of the eye Cough containing mucus or pink, frothy material from fluid buildup in the lungs Shortness of breath, from fluid buildup in the lungs General ill feeling (malaise), drowsiness, confusion [m.ufhealth.org]
Skin
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Palpable Purpura
In both criteria, palpable purpura is a mandatory criterion. [bmj.com]
Physical examination is significant for scleral icterus, hepatomegaly, and palpable purpura. Serology shows decreased C3 and C4 levels and elevated anti-hepatitis C antibodies. [step2.medbullets.com]
Neurologic
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Forgetful
More NCLEX Quizzes Don’t forget to tell your friends about this quiz by sharing it your Facebook, Twitter, and other social media. You can also take more fun nursing quizzes. [registerednursern.com]
Workup
Renal ultrasound may be ordered as part of the workup for acute renal failure, however, there are no pathognomonic signs for AIN on ultrasound. F. Over-utilized or “wasted” diagnostic tests associated with this diagnosis. [clinicaladvisor.com]
Diagnosis of Nephrotic Syndrome Because of these considerations, our recommendations for the initial workup of adults with nephrotic syndrome are outlined in Table 6. [jamanetwork.com]
Histopathologic changes include swelling of the glomerular tufts and infiltration with polymorphonucleocytes (see Workup: Histologic Findings ). Immunofluorescence reveals deposition of immunoglobulins and complement. [emedicine.medscape.com]
Urine
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Hypocalciuria
Abstract Hypocalciuria was found in the early stages of illness in six patients aged 12 to 30 with acute nephritis. The hypocalciuria does not appear to be due to hypocalcaemia, lowered glomerular filtration rate, or hypoparathyroidism. [ncbi.nlm.nih.gov]
Microbiology
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Legionella Pneumophila
pneumophila, collagen vascular diseases (e.g., sarcoidosis), streptococcal infections, and transplant rejection. [healthcommunities.com]
The role of atypical pathogens: Mycoplasma pneumoniae, Chlamydia pneumoniae, and Legionella pneumophila in respiratory infection. Infect Dis Clin North Am 1998; 12: 569–92. 2. Principi N, Esposito S, Blasi F, Allegra L, and the Mowgli Study Group. [journals.lww.com]
Treatment
Treatment for Acute Glomerulonephritis (AGN) The goal of treatment is to stop the ongoing inflammation and lessen the degree of scarring that ensues. Depending on the diagnosis, there are different treatment strategies. [healthcommunities.com]
Abstract Alkavervir (Veriloid(R)), a new derivative of veratrum viride was used in the treatment of hypertension in ten children with acute nephritis. [ncbi.nlm.nih.gov]
The goal of treatment is to reduce glomerular inflammation. [medical-dictionary-search-engines.com]
The goal of treatment is to reduce inflammation in the kidney and control high blood pressure. [pennstatehershey.adam.com]
Prognosis
The prognosis depends on the underlying disease and the overall health of the patient. The occurrence of cardiopulmonary or neurologic complications worsens the prognosis. [emedicine.medscape.com]
Prognosis This depends on the underlying cause. The prognosis for nephritic syndrome caused by acute post-streptococcal glomerulonephritis in children is generally excellent. [patient.info]
Prognosis The prognosis of post-streptococcal glomerulonephritis is good. The Outcome in ANS associated with SLE, systemic vasculitis and Goodpasture’s syndrome is less favourable. [myvmc.com]
Etiology
In precise usage, disease denotes the structural and etiologic disease entity whereas failure denotes the dysfunction (lack of working well, that is, impaired renal function); but in common usage these meanings overlap; for example, the terms chronic [icd.codes]
Epidemic acute nephritis: Studies on etiology, natural history and prevention. Medicine 34: 431, 1955 PubMed Google Scholar 10. Kleiman H: Epidemic acute glomerulonephrits at Red Lake. Minn Med 37: 483, 1954 Google Scholar 11. [link.springer.com]
Acute GN has been documented as a rare complication of hepatitis A. [9] Attributing glomerulonephritis to a parasitic or fungal etiology requires the exclusion of a streptococcal infection. [emedicine.medscape.com]
Many etiologies of AIN have been recognized—including allergic/drug-induced, infectious, autoimmune/systemic, and idiopathic forms of disease. The most common etiology of AIN is drug-induced disease, which is thought to underlie 60–70% of cases. [nature.com]
Epidemiology
Manhas RS, Patwari A, Raina C, Singh A: Acute nephritis in Kashmiri children—A clinical and epidemiological profile (A study of 350 cases). Indian Pediatr 16: 1015, 1979 PubMed Google Scholar 4. [link.springer.com]
The TINU syndrome is less well described in adults. [3] Our objective is to describe the epidemiological, clinical, biological, and histological characteristics as well as treatment strategies and evolutive modalities in patients with the TINU syndrome [sjkdt.org]
[…] noninfectious causes of acute GN include the following: Guillain-Barré syndrome Irradiation of Wilms tumor Diphtheria-pertussis-tetanus (DPT) vaccine Serum sickness Epidermal growth factor receptor activation, [10] and possibly its inhibition by cetuximab [11] Epidemiology [emedicine.medscape.com]
Vijayakumar Drugs & Therapy Perspectives (2018) Tubulointerstitial nephritis and uveitis (TINU) syndrome: a systematic review of its epidemiology, demographics and risk factors Linda O. Okafor, Peter Hewins, Philip I. Murray & Alastair K. [nature.com]
Pathophysiology
AGN - PathophysiologyAGN - Pathophysiology OliguriaOliguria 1.1. Spasm of afferent arteriole (Spasm of afferent arteriole ( blood flow)blood flow) 2.2. [slideshare.net]
As a nurse providing care to a patient with these conditions, it is important to know the signs and symptoms, pathophysiology, nursing management, patient education, and treatment for these conditions. [registerednursern.com]
With the development of the microscope, Theodor Langhans (1839-1915) was later able to describe these pathophysiologic glomerular changes. [emedicine.medscape.com]
Prevention
Although significant advances have been made during the past decade in the prevention of attacks of rheumatic fever, little attention has been paid to the problem of preventive measures for acute nephritis. [annals.org]
Prevention Often, the disorder cannot be prevented, although treatment of illness and infection may help to reduce the risk. Images References Appel GB, Radhakrishnan. Glomerular disorders and nephrotic syndromes. In: Goldman L, Schafer AI, eds. [m.ufhealth.org]
Prevention Often, the disorder cannot be prevented, although treatment of illness and infection may help to reduce the risk. References Appel GB, Radhakrishnan. Glomerular disorders and nephrotic syndromes. In: Goldman L, Schafer AI, eds. [stelizabeth.com]