Acute otitis media (AOM) is the inflammation of the middle ear secondary to viral or bacterial infection. This disease is more prevalent in young children, especially those with risk factors. It is diagnosed based on the clinical presentation, history, physical exam including otoscopy, and appropriate testing when necessary.
Presentation
AOM occurs most predominantly between the ages of 3 to 18 months as it commonly affects children 2 years or younger [1]. Moreover, some children are prone to developing recurrent episodes.
Neonates with AOM present with irritability and/or trouble with feeding. Older children with this condition typically have fever, ear pain with ear tugging, conductive hearing loss, and possibly an upper respiratory tract infection (URTI). Other possible symptoms include nausea, emesis, diarrhea, and signs related to URTI. Note that hearing loss is common in both children and adults with AOM as well as otitis media with effusion (OME). Hearing does eventually recover [2].
In cases with tympanic membrane perforation, exudative discharge leaks out for a day or two and the pain quickly subsides.
Risk factors
It is important to consider the risk factors when evaluating the patient. These include prematurity, low birth weight, immunosuppression, allergies, exposure to tobacco and environmental pollutants, colder climates, low socioeconomic status, positive family history, and certain racial backgrounds (such as Native Americans). Children with craniofacial defects and neuromuscular disease may be predisposed as well. Finally, pacifier and bottle use, prone sleeping position, and daycare attendance are other contributing factors.
Physical exam
Notable findings suggestive of inflammation on pneumatic otoscopy include an erythematous tympanic membrane, purulent or serosanguinous effusion in the middle ear, and decreased mobility of the tympanic membrane. Bulging of the membrane is also observed.
Entire Body System
- Fever
>br> Related Cases Disease Acute Otitis Media Ear Infections Symptom/Presentation Crying and Colic Fever and Fever of Unknown Origin Ear Pain Rhinitis”>Rhinitis Sleep Disturbance Specialty General Pediatrics Otolaryngology Age Infant To Learn More To [pediatriceducation.org]
The combination of these signs with ear pain or fever confirms the diagnosis of AOM. [medicalguidelines.msf.org]
Review after 48 hours 17. 48 hours review • Earache + fever persists: change to higher antibiotic. • If T.M. is bulging perform myringotomy. [slideshare.net]
Only fever was an exception, because children with bilateral AOM had fevers more often and fevers that were slightly higher. This was a new finding. [pediatrics.aappublications.org]
Other symptoms include trouble hearing, fever, fluid drainage from ears, dizziness and congestion. [clinicaladvisor.com]
- Inflammation
OBJECTIVE: Conventional treatment for acute otitis media mainly targets bacteria with antibiotics, neglecting to control for mediators of inflammation. [ncbi.nlm.nih.gov]
The persistence of an effusion beyond three months without signs of infection defines otitis media with effusion, whereas chronic suppurative otitis media is characterised by continuing inflammation in the middle ear giving rise to otorrhoea and a perforated [bmj.com]
Acute otitis media is an acute inflammation of the middle ear cavity. It is a common condition, occurring most frequently in children, and is often bilateral. [gpnotebook.co.uk]
- Asymptomatic
The first step in bacterial pathogenesis of AOM is the establishment of asymptomatic colonization in the nasopharynx. [ncbi.nlm.nih.gov]
No treatment if asymptomatic Tympanosclerosis: Surgical removal or Hearing aid [quizlet.com]
[…] thought to be due to eustachian tube dysfunction Pathophysiology: : ETD causes negative middle ear pressure → triggers formation of transudate → dysfunctional eustachian tube prevents adequate drainage → accumulation of fluid Clinical features May be asymptomatic [amboss.com]
- Surgical Procedure
GS should be suspected in a child presenting with torticollis after an upper respiratory tract infection or an ENT surgical procedure. [ncbi.nlm.nih.gov]
This surgical procedure involves making a small opening in the eardrum to drain the fluid and relieve the pressure from the middle ear. [chop.edu]
Where necessary, other surgical procedures, such as removal of the adenoids, may be required. Alternative treatments: A number of homeopathic treatments such as Pulsitilla and Ferrum phosphoricum are claimed to be useful in the treatment of glue ear. [independent.ie]
- Acute Onset of Symptoms
The diagnosis is based on acute onset of symptoms such as otalgia and fever, middle ear inflammation such as erythema of the tympanic membrane, and middle ear effusion. [ncbi.nlm.nih.gov]
[…] of discouloured tympanic membrane) Acute onset of symptoms General symptoms of AOM include rapid onset of ear pain or unexplained irritability in a preverbal child. [pedscases.com]
It is characterized by an acute onset of symptoms (e.g., otalgia, fever, anorexia) with signs of middle ear inflammation (e.g., bulging tympanic membrane, effusion). [amboss.com]
Presentation Symptoms AOM commonly presents with acute onset of symptoms: Pain (younger children may pull at the ear). Malaise. Irritability, crying, poor feeding, restlessness. Fever. Coryza/rhinorrhoea. Vomiting. [patient.info]
Diagnostic criteria for AOM AOM is characterized by acute onset of symptoms (eg, otalgia or suspected otalgia) with middle ear fluid and significant inflammation of the middle ear. [cps.ca]
Ears
- Otalgia
AOM is an inflammatory process that affects the mucosa of the middle ear and is characterized by fever and otalgia. [pediatriceducation.org]
It is characterized by an acute onset of symptoms (e.g., otalgia, fever, anorexia) with signs of middle ear inflammation (e.g., bulging tympanic membrane, effusion). [amboss.com]
Acute suppurative otitis media (ASOM) - A history of gradually increasing otalgia followed by the appearance of a discharge with some reduction in otalgia. Patients sometimes hear/feel a 'pop' just before the discharge appears. [entsho.com]
The diagnosis is based on acute onset of symptoms such as otalgia and fever, middle ear inflammation such as erythema of the tympanic membrane, and middle ear effusion. [ncbi.nlm.nih.gov]
Diagnostic criteria Presents as severe otalgia and deafness. The tympanic membrane is red and bulging, perforation can occur leading to purulent otorrhoea. Often the otalgia settles when perforation occurs. [gloshospitals.nhs.uk]
- Ear Discharge
A 32-year-old woman developed altered consciousness two days after initial symptoms of acute otitis media, with purulent discharge from the right ear. [ncbi.nlm.nih.gov]
Perforation of the tympanic membrane can occur, with associated purulent ear discharge. Investigations Investigations are rarely required in the evaluation of AOM. [gponline.com]
Six of the 14 children with fresh discharge in their ear canal had an intact or functionally intact TM. [bmcpediatr.biomedcentral.com]
- Tinnitus
People with severe tinnitus may have trouble hearing, working and sleeping. At this time, there is no cure for tinnitus and there are no FDA-approved drug treatments for this debilitating condition. [otonomy.com]
Early symptoms included otalgia, progressive sensorineural hearing loss, and tinnitus with inflammation of the tympanic membrane. During the second week a conductive component emerged resulting in a 60-dB mixed loss in the 2- to 4-kHz region. [ncbi.nlm.nih.gov]
Learn More About Topic Tinnitus Over 50 million Americans have experienced tinnitus, or ringing in ears, which is the perception of sound without an external source being present. [entnet.org]
- Hearing Problem
RESULTS: Recurrent acute otitis media subjects reported hearing problems comparable to those of the controls. Pure tone audiometry, at 125-8000 Hz, did not differ between groups. [ncbi.nlm.nih.gov]
In general, otitis media is not serious and does not normally cause permanent hearing problems if treated properly. Most often, otitis media is cured in the home by means of medication. [hear-it.org]
This can cause hearing problems and other serious complications. Symptoms The onset of signs and symptoms of ear infection is usually rapid. [mayoclinic.org]
Can Ear Infections Affect Hearing? Fluid buildup in the middle ear also blocks sound, which can lead to temporary hearing problems. [kidshealth.org]
- Erythematous Tympanic Membrane
Physical exam Notable findings suggestive of inflammation on pneumatic otoscopy include an erythematous tympanic membrane, purulent or serosanguinous effusion in the middle ear, and decreased mobility of the tympanic membrane. [symptoma.com]
Erythematous tympanic membranes may be due to viral infection, crying, or efforts to remove cerumen. Fever or irritability may or may not be present. [coreem.net]
Normal Tympanic Membrane Pink Tympanic Membrane, often seen with fever or upper respiratory tract infections Bulging and erythematous Tympanic Membrane in AOM Otitis Media with Effusion "glue ear" Middle ear effusion Loss of TM landmarks, particularly [rch.org.au]
On otoscopy, the tympanic membrane (TM) will look erythematous and may be bulging. If this fluid pressure has perforated the TM*, there may be a small tear visible with purulent discharge in the auditory canal. [teachmesurgery.com]
Face, Head & Neck
- Facial Pain
Severe facial pain and diplopia are a consequence of inflammatory neuralgia of the 5th and 6th cranial nerves respectively, known as Gradenigo's syndrome.8 It can also affect the vidian nerve presenting with vasomotor rhinitis – symptoms known as Vail's [elsevier.es]
Neurologic
- Dizziness
Other symptoms include trouble hearing, fever, fluid drainage from ears, dizziness and congestion. [clinicaladvisor.com]
Clinical course and diagnosis The symptoms of otitis media are earache, discharge from the ear, hearing loss, ear popping, ear fullness, dizziness, and fever. [ncbi.nlm.nih.gov]
ENT specialists treat conditions such as ear infection, hearing loss, dizziness, ringing in the ears (called tinnitus), ear, face, or neck pain, and more. [entnet.org]
Hold the bottle in your hand to warm it – cold ear drops can make you feel dizzy. Lie on your side with the affected ear facing up to put the drops in. Gently pull and push your ear to work the drops in. [nhs.uk]
- Vertigo
Benign Paroxysmal Positional Vertigo (BPPV) Benign paroxysmal positional vertigo, or BPPV, is the most common inner ear problem and cause of vertigo, or false sense of spinning. [entnet.org]
Videos of doctor Vertigo: causes, symptoms, and treatmen... What are the signs of hearing loss in m... How can I tell if my child has glue ear... [topdoctors.co.uk]
There are many causes and types of balance disorders including benign positional vertigo, labyrinthitis, vestibular neuritis, and Ménière’s disease. [otonomy.com]
Clinical features Severe vertigo, nausea, and vomiting Hearing loss Nystagmus towards healthy ear for weeks to months Diagnostics Change of lateralization in Weber's test Audiometry: sensorineural hearing loss Treatment Peripheral facial palsy Otogenic [amboss.com]
- Febrile Seizures
seizures Tender mastoid in late stages In older children Otalgia/earache, commonly with throbbing Hearing loss in the affected ear Fever Tender mastoid in late stages References:[1][2] Diagnostics Otoscopy: tympanic membrane (TM) evaluation Early findings [amboss.com]
Workup
To establish the diagnosis, the clinician will evaluate the patient's clinical manifestations, history, and risk factors. Also crucial is the physical exam including otoscopy. Testing may be warranted in some cases as explained below.
According to clinical practice guidelines set forth by the American Academy of Pediatrics and the American Academy of Family Physicians [3], diagnostic criteria include the presence of tympanic membrane bulging, recent onset of otorrhea (in the absence of external otitis media), middle ear effusion, and ear pain or tugging.
Procedure
Tympanocentesis is performed through piercing of the tympanic membrane and aspiration of the contents. This procedure is indicated in infants less than 6 weeks of age since AOM in this age group may be attributed to unusual organisms. Additionally, patients with failed treatment or signs indicative of sepsis should undergo this procedure. Finally, some patients will need a culture to determine the appropriate management, especially with the emergence of antibacterial resistance hindering treatment [4].
Imaging
Computed tomography (CT) or magnetic resonance imaging (MRI) are obtained if complications are suspected.
Treatment
Treatment Systematic reviews of antibiotic treatment conclude that there is only weak evidence that routine antibiotic treatment improves the course and outcomes of AOM. [ncbi.nlm.nih.gov]
Amoxicillin Clavulanate Potassium in the Treatment of Children with Acute Otitis Media with Effusion. [dx.doi.org]
Prognosis
Physicians should understand the etiology, pathophysiology, treatment options, and prognosis of facial palsy in association with otitis media. [ncbi.nlm.nih.gov]
Patients who have a bad prognosis in electrophysiological tests also have indication of surgery 3. [scielo.br]
With appropriate treatment Acute Ear Infection has excellent prognosis. [dovemed.com]
[…] activity or sleep) Reference: (1) MeReC Bulletin 2006;17(3):9-11. (2) Subcommittee on management of acute otitis media.Pediatrics 2004;113:1451-1465 Links: aetiology incidence infective organisms pathology clinical features management complications prognosis [gpnotebook.co.uk]
Etiology
Multibacterial etiology was seen in 34 (38%) samples, and M. catarrhalis was detected in most (85%) of those cases. Fifteen signals for M. catarrhalis were strong, suggesting a highly probable etiological role of the pathogen. [ncbi.nlm.nih.gov]
Acute otitis media Summary Epidemiology Etiology Etiology Risk Factors for AOM Pathophysiology Clinical features Diagnostics Treatment Complications Intratemporal complications Intracranial complications [amboss.com]
Epidemiology
BACKGROUND: Although acute otitis media (AOM) remains a major public health problem worldwide and brings economic burden on health care system and caregivers, little information is available about its epidemiology in Eastern Europe. [ncbi.nlm.nih.gov]
Epidemiology Highest incidence between 6–24 months of age Immunization of infants against pneumococci has decreased the incidence of AOM References:[1][2] Epidemiological data refers to the US, unless otherwise specified. [amboss.com]
Pathophysiology
Physicians should understand the etiology, pathophysiology, treatment options, and prognosis of facial palsy in association with otitis media. [ncbi.nlm.nih.gov]
Published on Jan 22, 2020 In this video, the viewer will learn the common risk factors and basic epidemiology, pathophysiology, recognize the clinical presentation and management as well as differentiate between acute otitis media, otitis media with effusion [youtube.com]
Acute otitis media Summary Epidemiology Etiology Etiology Risk Factors for AOM Pathophysiology Clinical features Diagnostics Treatment Complications Intratemporal complications Intracranial complications [amboss.com]
Pathophysiology: Obstruction to the eustachean tube seem to be the most important antecendent event in the pathophysiology of acute suppurative otitis media. [drtbalu.com]
Prevention
There remains a need to develop improved vaccines for prevention of NTHi disease, which could be achieved by combining protein D with other antigens. [ncbi.nlm.nih.gov]
Prevention Taking care to prevent the spread of colds or the flu in the home and community can help prevent some cases of otitis media. [ada.com]
Patient Information
References
- Paradise JL, Rockette HE, Colborn DK, et al. Otitis media in 2253 Pittsburgh-area infants: prevalence and risk factors during the first two years of life. Pediatrics. 1997; 99(3):318-33.
- McDonald S, Langton Hewer CD, et al. Grommets (ventilation tubes) for recurrent acute otitis media in children. Cochrane Database of Systemic Reviews. 2008; (4):CD004741.
- Lieberthal AS, Carroll AE, Chonmaitree T, et al. The diagnosis and management of acute otitis media. Pediatrics. 2013; 131(3):e964-99.
- Block SL. Causative pathogens, antibiotic resistance and therapeutic considerations in acute otitis media. The Pediatric Infectious Disease Journal. 1997; 16(4):449-56.