Vomiting and constipation were present in 4 patients, diarrhea and constipation were alternatively present in 1 patient, abdominal distention and abdominal pain were present in 2 patients. (4) Cardiovascular system manifestations included postural dizziness [ncbi.nlm.nih.gov]

In two instances, signs and symptoms of a small-fiber sensory neuropathy were present. [mayoclinic.pure.elsevier.com]

The purpose of this book is to present a focused approach to the pathophysiology, diagnosis, and management of the most common autonomic disorders that may present to the clinical neurologist. Autonomic Neurology is divided into 3 sections. [books.google.com]

• Inflammation

  Definition Guillain-Barre syndrome or acute inflammatory demyelinating polyneuropathy is an acute inflammation that causes nerve cell damage without an obvious cause. [nanda-nurse-diary.blogspot.com]

  Recent advances in basic and preclinical science reveal that reflex neural circuits inhibit the production of cytokines and inflammation in several animal models. [read.qxmd.com]

  Biopsies show Wallerian-like degeneration without significant lymphocytic inflammation. Many cases have been reported in rural areas of China, especially in children and young adults during the summer months. [gbs-cidp-nsw.org.au]

  Cerebrospinal fluid neopterin in paediatric neurology: a marker of active central nervous system inflammation. Developmental Medicine and Child Neurology, 51(4), 317-323. [sydney.edu.au]

• Myxedema

  We thought that this was the cause of all my problems since I’d started to go into a myxedema crisis but was unfortunately just an incidental finding. My hypothyroidism is caused by a common autoimmune disease called Hashimoto’s disease. [princessonthesofa.wordpress.com]

  […] nodosa Systemic lupus erythematosus Sjögren's syndrome Sarcoidosis Leprosy HIV/AIDS Multifocal variant of CIDP Hereditary predisposition to pressure palsies TABLE 1 Neuropathies by Pattern of Involvement Focal Entrapment Common sites of compression Myxedema [aafp.org]

• Anhidrosis

  An Zhihua Department of Neurology,General Hospital of Tianjin,Da Gang Oil Field A case of acute pandysautonomia with clinical manifestations of orthostatic hypo-tension,pupillotonia,anhidrosis,impotence,constipation,difficulty of urinationand dryness [en.cnki.com.cn]

  Acute pandysautonomia/acute autonomic neuropathy Acute pandysautonomia/acute autonomic neuropathy (ANN): Rare; involvement of both sympathetic and parasympathetic nervous systems; somatic fibres not affected; rare; usually have orthostatic hypotension, anhidrosis [podiapaedia.org]

  Patients may suffer from orthostatic hypotension, bradycardia, anhidrosis, unreactive pupils, ptosis, decreased lacrimation and salivation, gastrointestinal paresis, and impaired genitourinary function. [ejpn-journal.com]

  The TST can be useful in monitoring progression of idiopathic anhidrosis and Sjögren's syndrome where prominent anhidrosis/hypohidrosis occurs. [ihpotblogspot.blogspot.com]

  Common symptoms include orthostatic hypotension, decreased papillary reactivity, anhidrosis, bladder dysfunction, gastrointestinal hypomobility, and sicca symptoms. [mafiadoc.com]

• Abnormal Sweating

  She denied blurring of vision or abnormality of sweating. She experienced nausea, malaise, and abdominal distension but attributed these symptoms to cancer treatment. Examination revealed mild cachexia and orthostatic hypotension. [clinicalsciences.wordpress.com]

• Hypertrichosis

  Clinical alerts include skin changes (hyperpigmentation, hypertrichosis, acrocyanosis, flushing, white nails), oedema, pleural effusion or ascites, papilledema, weight loss, severe muscular deterioration not responding to usual therapies used in CIDP. [mjhid.org]

• Dysautonomia

  […] tachycardia syndrome and chronic intestinal pseudoobstruction), and chronic dysautonomia, mimicking pure autonomic failure. " More about dysautonomia: Autoimmune Dysautonomia Evaluation Limited dysautonomia : "With limited dysautonomia the symptoms are [followmeindenmark.blogspot.com]

  Phenotypic and neuropathologic heterogeneity of anti-Hu antibody-related paraneoplastic syndrome presenting with progressive dysautonomia: report of two cases. [link.springer.com]

  Symptoms - Acute cholinergic dysautonomia Causes - Acute cholinergic dysautonomia Not supplied. Prevention - Acute cholinergic dysautonomia Not supplied. Diagnosis - Acute cholinergic dysautonomia Not supplied. [checkorphan.org]

  Some cases have only shown a cholinergic dysautonomia, while others have displayed a loss of autonomic function together with other impairments of nervous function. [unboundmedicine.com]

  Pure pan-dysautonomia with recovery. Trans Am Neurol Assoc. 1969;94:355–357. [PubMed] [Google Scholar] Andersen O, Lindberg J, Modigh K, Reske-Nielsen E. Subacute dysautonomia with incomplete recovery. Acta Neurol Scand. 1972;48(4):510–519. [ncbi.nlm.nih.gov]

• Paresthesia

  Definition Guillain-Barre syndrome (GBS) is a type of acute inflammatory neuropathy. [1] [2] It is a clinically defined syndrome characterized by motor difficulty, absence of deep tendon reflexes, paresthesias without objective sensory loss, and increased [online.epocrates.com]

  Loss of function “- symptoms” Disordered function “+ symptoms” Sensory “Large Fiber” ↓ Vibration ↓ Proprioception Hyporeflexia Sensory ataxia Paresthesias Sensory “Small Fiber” ↓ Pain ↓ Temperature Dysesthesias Allodynia The clinical response to sensory [slideshare.net]

  Manual muscle test was intact, and showed no signs of hypesthesia or paresthesia in sensory nervous system. Deep tendon reflexes were decreased bilaterally at both lower extremities. There were no abnormalities in cerebellar function tests. [e-sciencecentral.org]

  This is associated with distal paresthesias and loss of deep tendon reflexes. Progression is often maximal by the end of 4 weeks, then the condition usually plateaus before slowly improving. [emedicine.medscape.com]

  He started to improve in his motor power within 3 weeks, but continued to have paresthesia for 6-8 months which partially responded to gabapentin. A year later he was neurologically asymptomatic. [ispub.com]

• Hyporeflexia

  Loss of function “- symptoms” Disturbed function “+ symptoms” Motor nerves Large fibre Wasting Hypotonia Weakness Hyporeflexia Orthopedic deformity Fasciculation Cramps The clinical response to motor nerve injury 7. [slideshare.net]

  Despite progressive symmetrical muscle weakness, the adolescent did not present one of the criteria rated as necessary by Ashbury and Cornblath (Table 1), for establishing the diagnosis: areflexia or hyporeflexia. [adolescenciaesaude.com]

  In a typical case, mental, motor, and sensory functions are intact, but mild sensory disturbances or hyporeflexia may be present (Appenzeller and Kornfeld 1973; Low et al 1983). [clinicalsciences.wordpress.com]

• Difficulty Concentrating

  In the absence of an apparent emergent condition and in the context of now chronic symptoms, her observed tachycardia when standing associated with nausea, lightheadedness, fatigue, and difficulty concentrating suggests Postural Orthostatic Tachycardia [mededmasters.com]

• Facial Muscle Weakness

  Extra ocular movements were normal; no facial muscles weakness and other cranial nerves were normal. Fundus was normal. Motor system examination showed power proximally 4/5 and distally 3/5 in both upper and lower limbs. [ispub.com]

• Urinary Hesitancy

  Nine months later the patient developed syncope on standing, abdominal distention, constipation, anhi-drosis, dryness of the mouth and eyes, urinary hesitancy, and cold intolerance over a three-week period. [dokumen.tips]

Additional workup included: the tumormarker Cyfra 211 and NSE were initially elevated, 2 month later nor-mal. [docslide.net]

Lest you think I suddenly became really smart, I got this information from the following: Medscape: Autonomic Neuropathy Workup, Medical Paper You need to have a complete blood count, basic metabolic panel, liver function testing, and immunoelectrophoresis [ihpotblogspot.blogspot.com]

Additional workup included: the tumormarker Cyfr a 21–1 and NSE were initially elevated, 2½ month later nor- mal. [researchgate.net]

Diagnostic workup The diagnosis is primarily based on recognizing the acute or subacute development of widespread autonomic dysfunction with preserved motor and sensory functions. [clinicalsciences.wordpress.com]

Polymyositis: Differential diagnoses & workup. Omaha, NE: eMedicine.com; updated November 6, 2009. Available at: http://emedicine.medscape.com/article/335925-diagnosis. Accessed March 15, 2010. Kalluri M, Sahn SA, Oddis CV, et al. [aetna.com]

Treatment of AAG is based on case reports. It is clear that AAG patients respond to immunomodulatory treatments but combination immunotherapy may be required to achieve a clinical response. [researchgate.net]

Symptomatic treatment is complex and is helpful in supporting function. If an autoimmune etiology is identified immunomodulatory treatments should be employed early in the course to avoid progressive disability. [medlink.com]

The findings are consistent with a dysimmune pathogenesis for this syndrome and suggest a possible treatment for future cases. [jnnp.bmj.com]

The majority of cases have a poor prognosis with a chronic debilitating course. [ncbi.nlm.nih.gov]

Source MeSH Acute Disease Autonomic Nervous System Diseases Chronic Disease Humans Prognosis Pub Type(s) Journal Article Review Language eng PubMed ID 2486239 TY - JOUR T1 - Acute curable pandysautonomia and chronic progressive pandysautonomia. [unboundmedicine.com]

Th e majority of cases have a poor prognosis with a chronic de-bilitating course. [docslide.net]

Further tests failed to find a cause of acute neuropathy especially where there was no evidence for paraneoplastic or infectious etiology. The patient was treated with high dose intravenous prednisolone and completely recovered. [ncbi.nlm.nih.gov]

Paraneoplastic disease was also found as a possible etiology in a few cases [6, 7]. [mafiadoc.com]

It is used for serological evaluation of patients who present with a subacute neurological disorder of undetermined etiology, especially those with known risk factors for cancer. [healthtap.com]

If an autoimmune etiology is identified immunomodulatory treatments should be employed early in the course to avoid progressive disability. [medlink.com]

The epidemiology of Guillain-Barré syndrome worldwide. A systematic literature review. Neuroepidemiology 2009; 32 (2) 150-163 5 Rocha MS, Brucki SM, Carvalho AA, Lima UW. Epidemiologic features of Guillain-Barré syndrome in São Paulo, Brazil. [thieme-connect.com]

All patients from a database including sera sent for routine antiganglioside-antibody testing and fulfilling ASAN criteria were collected and their epidemiological, clinical and electrophysiological features analyzed. [oatd.org]

There is a clear epidemiological relationship to antecedent infections, the best characterized of which is with campylobacter jejuni enteritis. [clinicaladvisor.com]

Epidemiology In general, these can occur in men and women at any age, but the epidemiology will depend on the particular cause. Some causes are very rare. [patient.info]

Epidemiology Acute pandysautonomia is a rare disorder affecting all ages (range 9 to 74 years) and both sexes. No specific information on epidemiology is available. Prevention No information was provided by the author. [clinicalsciences.wordpress.com]

The purpose of this book is to present a focused approach to the pathophysiology, diagnosis, and management of the most common autonomic disorders that may present to the clinical neurologist. Autonomic Neurology is divided into 3 sections. [books.google.com]

And TRPA1 and vasodilation is connected: Evidence for the pathophysiological relevance of TRPA1 receptors in the cardiovascular system in vivo "TRPA1 is involved in mediating vasodilation. [followmeindenmark.blogspot.com]

Rapidly find the answers you need with separate sections on diseases and disorders, differential diagnosis, clinical algorithms, laboratory results, and clinical preventive services, plus an at-a-glance format that uses cross-references, outlines, bullets [books.google.com]

Collaborative Meta-Analysis of Randomised Trials of Antiplatelet Therapy for Prevention of Death, Myocardial Infarction, and Stroke in High Risk Patients. ‎ [books.google.es]