Older patients more often present with VZV or HSV-1 infections while younger patients more often present with HSV-2 infections. [eyewiki.aao.org]

Treatment of Acute Retinal Necrosis Syndrome with Oral Antiviral Medications. Ophthalmology 2007, 114: 307–312. Aslanides IM, De Souza S, Wong DT, et al. Oral valacyclovir in the treatment of acute retinal necrosis syndrome. [eyewiki.aao.org]

Complications Many cases finally have less than 20/200 due to Retinal holes and tears Retinal detachment Proliferative vitreoretinopathy Vitreous hemorrhage Macular pucker Optic neuropathy- pallor of the optic disc Encephalitis Prognosis The visual outcome [eyewiki.aao.org]

Maghreb Med. 1995; (295): 54- Maghreb Medical Journal Country: Tunisia P-ISSN: 0330-258X Type of Publication: Case Reports Keywords: Retinal Necrosis Syndrome, Acute / Etiology Broad Subjects: Herpesvirus 3, Human ,pathogenicity ,Cytomegalovirus ,pathogenicity [vlibrary.emro.who.int]

Etiology ARN is believed to be caused by a viral infection. Most often the causative viral agent is either VZV or less commonly HSV. [eyewiki.aao.org]

Epidemiology This clinical entity is uncommon in the pediatric population. Most often it affects healthy, immunocompetent adults in their fifth to seventh decade. A clear racial or gender predilection has not been consistently demonstrated. [eyewiki.aao.org]

Pathophysiology Acute Herpetic Phase: Viral particles in the retina and vitreous provoke an intense inflammatory response. Retinal opacification corresponds with infiltration of the retina with viral particles and mononuclear cells. [eyewiki.aao.org]

The rates of success in preventing retinal detachment are variable, and consensus does not exist on whether laser demarcation should be employed. [eyewiki.aao.org]