IV q12h) Valganciclovir (900 mg twice daily orally for 3 weeks induction, then 450 mg twice daily po for maintenance) Antiviral agents administered intravitreally can provide beneficial adjunctive therapy, especially if retinitis is threatening the macula [eyewiki.aao.org]

Physical examination Anterior segment involvement may include episcleritis, scleritis, corneal edema, keratic precipitates, and anterior chamber inflammation. [eyewiki.aao.org]

An animal model of ARN suggests that involvement in the contralateral eye occurs via retrograde axonal transport to the hypothalamus and the contralateral retina. [eyewiki.aao.org]

Risk factors Genetics are believed to play a role in an individual’s risk for ARN with antigen expression of: HLA-DQw7, HLA-Bw62, and HLA-DR4 in American Caucasian populations and HLA-Aw33, HLA-B44, and HLA-DRw6 in Japanese populations. [eyewiki.aao.org]