Presentation
When minor manifestations alone are present, the exclusion of other more likely causes of the clinical presentation is recommended before a diagnosis of an ARF recurrence is made (Class I, Level of Evidence C). [acc.org]
Low-grade carditis may present too late for diagnosis of the RF. [patient.info]
INVESTIGATIONS • ECG: Sinus tachycardia Sinus bradycardia First-degree atrioventricular (AV) block (prolongation of the PR interval) ST segment elevation may be present and is marked most in lead II, III, aVF, and V4 -V6 28 29. [slideshare.net]
This report examines and presents a range of data on acute rheumatic fever (ARF) and rheumatic heart disease (RHD) in Australia. [aihw.gov.au]
Respiratoric
- Persistent Cough
Symptoms may be seen in the form of shortness of breath, persistent cough, rapid heartbeat (tachycardia), chest pain, and feeling of tiredness all the time. [nhp.gov.in]
Psychiatrical
- Emotional Outbursts
It can also be associated with muscle weakness and emotional outbursts. Because of antibiotics, rheumatic fever is now rare in developed countries. [webmd.com]
outbursts, such as crying or laughing for no apparent reason. [nhp.gov.in]
Treatment
“Our program is improving long-term compliance to treatment with the main aim of reducing cardiac morbidity rates in the Townsville HHS.” [health.qld.gov.au]
Following an initial diagnosis of ARF, patients require long-term treatment, including long-term antibiotic treatment to avoid further infections that may damage the heart (RHD et al, 2012; AIHW, 2013b). [pmc.gov.au]
Treatment for rheumatic heart disease: Specific treatment for rheumatic heart disease will be determined by your child's physician based on: Your child's overall health and medical history Extent of the disease Your child's tolerance for specific medications [chw.org]
This can take years to show up, so you may need regular check-ups and further treatment when you're older. [nhs.uk]
Early treatment of streptococcal sore throat can prevent the development of rheumatic fever. [nhp.gov.in]
Prognosis
Rheumatic fever occurs in equal numbers in males and females, but the prognosis is worse for females than for males. [emedicine.medscape.com]
The average age among participants who died in our study was 29.4 years, confirming the aggressive nature and poor prognosis of RHD in Uganda. [bmccardiovascdisord.biomedcentral.com]
PROGNOSIS OF RHEUMATIC FEVER • Presence or absence of permanent cardiac damage • Cardiac status at the start of treatment • Recurrence of rheumatic fever • Regression of heart disease 41 42. [slideshare.net]
Insights into prognosis of valvular aortic stenosis. Circulation. 1994; 89 (2):642–650. [ PubMed : 8313553 ] Paar J. A., Berrios N. M., Rose J. D., Cáceres M., Peña R., Pérez W., et al. [ncbi.nlm.nih.gov]
Prognosis Rheumatic heart disease occurs in 30-45% of patients with acute RF [ 20 ]. Severe chronic valvular disease is associated with severe carditis and recurrent RF [ 21 ]. [patient.info]
Etiology
This raises the possibility of an autoimmune etiology. [histopathology-india.net]
The pathogenesis of RHD is complex with both environmental and genetic factors contributing to its etiology. [clinicaltrials.gov]
New observations on the etiology of aortic valve disease: a surgical pathologic study of 236 cases from 1990. Hum Pathol. 1993 Dec. 24(12):1330-8. [Medline]. Veinot JP. Pathology of inflammatory native valvular heart disease. [emedicine.medscape.com]
"Association of Mannose-Binding Lectin Gene Polymorphism but Not of Mannose-Binding Serine Protease 2 with Chronic Severe Aortic Regurgitation of Rheumatic Etiology". Clinical and Vaccine Immunology : CVI 15 (6): 932–936. doi:10.1128/CVI.00324-07. [textbookofcardiology.org]
Group A streptococcal (GAS) pharyngitis is the etiologic precursor of acute rheumatic fever, but host and environmental factors are important. [merckmanuals.com]
Epidemiology
Keywords: rheumatic fever, rheumatic heart disease, group A streptococcus, epidemiology This work is published and licensed by Dove Medical Press Limited. [dovepress.com]
Epidemiologic implications: It is reasonable to consider individuals at low risk of ARF if they come from a setting or population with known low rates of ARF and RHD (Class IIa, Level of Evidence C). [acc.org]
Search Strategy A literature search was performed on PubMed to identify studies that described the epidemiology of acute rheumatic fever and rheumatic heart disease. [pubs.sciepub.com]
OBJECTIVES To know about the epidemiology of the disease To understand the pathogenesis of rheumatic heart disease To know about the clinical features: cardiac & non-cardiac manifestations To learn about the laboratory studies of RHD To understand [slideshare.net]
This review summarizes these findings and provides a clinical perspective on ARF/RHD pathogenesis, epidemiology, diagnosis, prevention, management and control. [link.springer.com]
Pathophysiology
Pathophysiology of rheumatic heart disease Micrograph showing an Aschoff body (right of image), as seen in rheumatic heart disease. [textbookofcardiology.org]
Essentials of pathophysiology: concepts of altered health states. Hagerstown, MD: Lippincott Williams & Wilkins. [en.wikipedia.org]
A comprehensive resource provided by the World Health Organization (WHO) addresses the diagnosis and treatment. [1] Pathophysiology Rheumatic fever develops in some children and adolescents following pharyngitis with group A beta-hemolytic Streptococcus [emedicine.medscape.com]
Moreover, heart-M protein cross-reactive T cells have been isolated from the myocardium and the valves of RHD patients suggesting their involvement in the pathophysiology of the disease [ 7, 8 ]. [link.springer.com]
Prevention
[…] on preventative action, diagnosis and management of acute rheumatic fever and rheumatic heart disease, and should be considered the difinitive source of information to guide all aspects of RHD management, prevention and control across Australia. [healthdirect.gov.au]
Different Preventions of RHD Type of Prevention Aim (What?) Modality (How?) [circ.ahajournals.org]
Following ARF diagnosis regular secondary prevention in the form of prophylaxis with antibiotic is started to prevent recurrent ARF and heart damage. [nhp.gov.in]
RHD registers are a central element of secondary disease prevention programs to prevent recurrence of ARF and reduce the occurrence or severity of RHD. [pmc.gov.au]
Quick reference guides cover the following topics: Primary prevention of ARF Diagnosis of ARF Management of ARF Secondary prevention of ARF Management of RHD RHD in pregnancy RHD control programs Access the guidelines and quick reference guides on the [heartfoundation.org.au]