We present a case of acute silicosis with bilateral pneumothorax of a 28-year-old man working at a stone crusher factory for 1 year. He presented to the emergency department with cough, respiratory distress and diffuse chest pain. [ncbi.nlm.nih.gov]

This pattern was present for both Alzheimer’s disease–related dementia and cerebrovascular disease etiologies, and persisted in analyses restricted to nonsmokers. [ajrccm.atsjournals.org]

• Constitutional Symptom

  Complicated Silicosis, dyspnea and productive cough often are accompanied by constitutional symptoms of malaise and weight loss Accelerated Silicosis -- occurs after exposure to larger amounts of silica over a shorter period of time (4-8 years). [silicosis.com]

• Hoarseness

  Patients with advanced silicosis may have trouble sleeping and experience chest pain, hoarseness, and loss of appetite. Silicosis patients are at high risk for Tuberculosis (TB). [silicosis.com]

• Skin Disease

  Hai Long, Guiying Zhang, Ling Wang and Qianjin Lu, Eosinophilic Skin Diseases: A Comprehensive Review, Clinical Reviews in Allergy & Immunology, 50, 2, (189), (2016). [doi.org]

After various investigations and treatments the symptoms persisted and a lung biopsy was performed. Pathologic analysis disclosed the presence of silicotic crystals within lung tissue and mediastinal lymph nodes. [ncbi.nlm.nih.gov]

Supportive treatment includes cough medicine, bronchodilators, and oxygen if needed. Antibiotics are prescribed for respiratory infections as needed. Treatment also includes limiting exposure to irritants and quitting smoking. [nlm.nih.gov]

Approvals in advanced disease have signified a landmark shift in the treatment paradigms of many cancers. [annonc.oxfordjournals.org]

Is there a medical cure or any effective treatment for silicosis ? (Silicosis Treatment) [silicosis.com]

There is no cure for silicosis, and, since there is no effective treatment, control of the disease lies mainly in prevention. [britannica.com]

There is an accelerated form that occurs within 4 to 10 years (some say 5 to 15 years) after exposure and has a more rapid progression of lung changes and a poorer prognosis and a chronic form that usually occurs greater than 10 and often 20 years (some [web.archive.org]

This pattern was present for both Alzheimer’s disease–related dementia and cerebrovascular disease etiologies, and persisted in analyses restricted to nonsmokers. [ajrccm.atsjournals.org]

If there is no progressive massive fibrosis and emphysema is present, then smoking plays a more significant role in the etiology of the emphysema and is often considered part of the etiology of the patient's disability. [web.archive.org]

Meletis and Ben Bramwell, Rheumatoid Arthritis: Etiology and Naturopathic Treatments, Alternative and Complementary Therapies, 7, 6, (347), (2001). Judy Van de Water, Hiromi Ishibashi, Ross L. Coppel and M. [doi.org]

DHHS (NIOSH) Publication Number 2004-146 The Worker Health Chartbook 2004 is a descriptive epidemiologic reference on occupational morbidity and mortality in the United States. [doi.org]

Modification of coal-induced lesions by Jaggery (gur): Part II--Pathophysiological evidence in rats. Indian J Exp Biol. 1988 Feb; 26 (2):112–117. [ PubMed ] [ Google Scholar ] Upreti RK, Sahu AP, Shukla L, Srivastava SN, Shanker R. [ncbi.nlm.nih.gov]

Shuko Murakami, Yasumitsu Nishimura, Megumi Maeda, Naoko Kumagai, Hiroaki Hayashi, Ying Chen, Masayasu Kusaka, Takumi Kishimoto and Takemi Otsuki, Cytokine alteration and speculated immunological pathophysiology in silicosis and asbestos-related diseases [doi.org]

"[14] Pathophysiology[edit] Slice of a lung affected by silicosis When small silica dust particles are inhaled, they can embed themselves deeply into the tiny alveolar sacs and ducts in the lungs, where oxygen and carbon dioxide gases are exchanged. [en.wikipedia.org]

Prevention Silicosis is prevented by avoiding inhalation of dust containing free crystalline silica. [web.archive.org]

Akiko Tomokuni, Takemi Otsuki, Haruko Sakaguchi, Yumika Isozaki, Fuminori Hyodoh, Masayasu Kusaka and Ayako Ueki, Detection of anti-topoisomerase I autoantibody in patients with silicosis, Environmental Health and Preventive Medicine, 10.1007/BF02898059 [doi.org]

This will prevent breathing problems from becoming severe, as well as further damage to your lungs. If you work in a high-risk occupation or have a high-risk hobby, always wear a dust mask and do not smoke. [nlm.nih.gov]

Further studies are needed to define the extent and severity of silicosis in this community and to examine possible preventive measures. [thorax.bmj.com]