Fever, paraparesis, quadri-paresis and bladder dysfunction were the most common presentations. Median score on disability rating scale (DRS) was twelve. [ncbi.nlm.nih.gov]

• Fecal Incontinence

  Deficits may progress over several more days to a complete transverse sensorimotor myelopathy, causing paraplegia, loss of sensation below the lesion, urinary retention, and fecal incontinence. [merckmanuals.com]

  On day 3, she developed retention of urine, fecal incontinence, and loss of sensation below neck level with sign of respiratory distress. She was given ventilatory support. [atmph.org]

  Autonomic dysfunction was defined as “positive” when the patient had medical record documentation of urinary urgency, urinary incontinence, fecal incontinence, tenesmus, or sexual dysfunction. [ceemjournal.org]

• Tenesmus

  Autonomic dysfunction was defined as “positive” when the patient had medical record documentation of urinary urgency, urinary incontinence, fecal incontinence, tenesmus, or sexual dysfunction. [ceemjournal.org]

• Back Pain

  We report a 31-year-old man who complained of back pain and claudication of both lower extremities. The patient showed typical inflammatory back pain and significant sacroiliitis, consistent with AS. [ekjm.org]

  These symptoms included bilateral lower extremity paresthesias, back pains in the thoracic and lumbar areas and pronounced lower extremity weakness. [ncbi.nlm.nih.gov]

  Remarkably, the patient reported only mild symptoms with severe back pain in the absence of profound signs of myelopathy. [karger.com]

  Symptoms range from back pain to more serious problems, such as paralysis or loss of bowel control. Multiple sclerosis connection Transverse myelitis is often a onetime illness. [healthline.com]

• Unable to Walk

  Eighty-nine percent were unable to walk, required assisted ventilation, or both. [ncbi.nlm.nih.gov]

  Only 9.4% of patients with IATM were unable to walk unassisted at the end of follow-up. [bmcneurol.biomedcentral.com]

  Approximately 50% of patients with this condition are unable to walk upon reaching their maximum level of disability, 3 and a third recover poorly and remain severely disabled. 4 In 2002, the Transverse Myelitis Consortium Working Group (TMCWG) proposed [elsevier.es]

• Hyperreflexia

  Flaccid weakness gradually changes to pyramidal tract signs, with hyperreflexia, clonus, and extensor responses. A sensory level (between T5-T10) affects primarily pain and temperature, and posterior columns are usually spared. [pediatricneurologybriefs.com]

  Neurological Examination: severe reduction of visual acuity in the right eye with papilledema, paraparesis (stage 4), hyperreflexia and signs of bilateral Babinski. [omicsonline.org]

  Clinical presentation Typical presentation • Prior history of fever (nonspecific viral illness) • ATM, the onset of spinal cord dysfunction usually progress in 4 hours to 21 days, the patient's signs usually plateau and evolve toward spasticity/hyperreflexia [slideshare.net]

  Sx: leg weakness, sphincter dysfunction, abnormal DTRs [acutely may be absent, but hyperreflexia the rule]. Sensory level helps distinguish from polio/Guillain-Barre (GB). [hopkinsguides.com]

• Pyramidal Tract Signs

  Flaccid weakness gradually changes to pyramidal tract signs, with hyperreflexia, clonus, and extensor responses. A sensory level (between T5-T10) affects primarily pain and temperature, and posterior columns are usually spared. [pediatricneurologybriefs.com]

• Urinary Retention

  We describe a 40-year-old man who presented with an acute onset quadriparesis with urinary retention, which was preceded by fever and headache 3 weeks prior. He had elevated IgM titres against JE virus in serum and cerebrospinal fluid. [ncbi.nlm.nih.gov]

  Acute urinary Retention, paraplegia, hypoesthesia. [omicsonline.org]

  Deficits may progress over several more days to a complete transverse sensorimotor myelopathy, causing paraplegia, loss of sensation below the lesion, urinary retention, and fecal incontinence. [merckmanuals.com]

  Physical therapy may also be helpful to retrain muscles necessary for improved bladder and bowel control and relief of constipation and urinary retention. [encyclopedia.com]

• Urinary Incontinence

  Autonomic dysfunction was defined as “positive” when the patient had medical record documentation of urinary urgency, urinary incontinence, fecal incontinence, tenesmus, or sexual dysfunction. [ceemjournal.org]

  Bladder and bowel problems.These problems may include an increased urinary urge, urinary incontinence, difficulty urinating and constipation. Prognosis of TM Generally, prognosis for complete recovery from TM is not good. [mytm.ca]

  Bladder dysfunction is an integral part in majority and could be the presenting symptom of transverse myelitis. [12] Its management is important to prevent recurrent urinary tract infection, preserve renal function, and manage urinary incontinence. [18 [ruralneuropractice.com]

  Weakness in the lower limbs, paraplegia and urinary incontinence. Neurological Examination: spastic paraplegia, Babinski sign bilateral patellar, hyperreflexia and aquiliana, sensorial level T4. Hyperintense Signal on T2 sequence between T2-T10. [omicsonline.org]

We evaluated the spectrum clinical features and paraclinical findings encountered during diagnostic workup and aiding the diagnosis. SETTING: Department of Neurology, Inselspital Bern, Switzerland. [ncbi.nlm.nih.gov]

Workup for the underlying cause was carried out, including serology for human immunodeficiency virus (HIV). [casereports.in]

There is scarce observational data and a lack of randomised controlled studies regarding the treatment of Sjoegren's syndrome in the presence of such complications. [ncbi.nlm.nih.gov]

Prognosis depends on a number of factors, and evidence suggests that the majority of children have a good outcome. [ncbi.nlm.nih.gov]

OBJECTIVE: To determine the presenting features and etiological classification of acute transverse myelitis (ATM) at Aga Khan University Hospital, a tertiary care hospital in Pakistan. [ncbi.nlm.nih.gov]

A controlled multicenter study is suggested to assess epidemiology, etiology and prognosis of ATM. [ncbi.nlm.nih.gov]

Provides in-depth coverage of CSF examination and analysis, CSF physiology and pathophysiology, approach to diagnosis, and future directions in CSF analysis. [books.google.de]

The significance of these findings and the possible role antiganglioside antibodies may play in acute transverse myelitis pathophysiology is discussed. [ncbi.nlm.nih.gov]

The pathophysiology of ATM consists primarily of inflammatory disorders, similar to the neurological complications of AS. We suggest that ATM is a possible extra-articular manifestation of AS. [ekjm.org]

•Postinfectious etiology largely predominates in children. 11. pathophysiology •Three hypotheses have been proposed: 1. Cell mediated autoimmune response 2. autoimmune vasculitis 3. direct viral invasion of spinal cord. 12. [slideshare.net]

Pathophysiology NA Epidemiology The incidence of transverse myelitis in children varies both geographically and over time, however, not in a predictable fashion. [clinicaladvisor.com]

Our report emphasizes that the Varicella zoster virus booster vaccine may be necessary to prevent not only acute varicella, but also its postinfectious neurologic complications. [ncbi.nlm.nih.gov]

SATM is often relapsing and prognosis depends on prevention of further episodes. The documents contained in this web site are presented for information purposes only. [orpha.net]