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Adenosine

Adenocard Injection


Presentation

  • We report an unusual presentation of X-ALD only with an isolated lesion of the cerebellar white matter and dentate nuclei.[ncbi.nlm.nih.gov]
  • Our subsequent management and follow-up is presented.[ncbi.nlm.nih.gov]
  • This interference invalidates ADA results and is present in 2% of our laboratory requests.[ncbi.nlm.nih.gov]
  • Patient 2: A 13-year-old boy with hereditary hemorrhagic teleangiectasia presented with an intracerebral hemorrhage from an aneurysm of the left MCA.[ncbi.nlm.nih.gov]
  • As hepatic P‑glycoprotein (P‑gp) serves a critical role in the disposition of drugs, the present study aimed to address whether P‑gp function could be affected by DEX in vitro.[ncbi.nlm.nih.gov]
Intravenous Administration
  • For that reason, asystole was chemically induced by the intravenous administration of adenosine. The surgery was successful, and the patient was discharged from the hospital on the 10th postoperative day.[ncbi.nlm.nih.gov]
  • administration in people with neuropathic pain.[clinicaltrials.gov]
  • Additionally, intravenous administration of Lexiscan also increased BBB permeability in rats ( Fig. 3 B ).[doi.org]
  • Comparison of effectiveness of high-dose intracoronary adenosine versus intravenous administration on the assessment of fractional flow reserve in patients with coronary heart disease.[circinterventions.ahajournals.org]
  • This lasts a few seconds after administration of a bolus dose, during transient asystole induced by intravenous administration.[en.wikipedia.org]
Developmental Delay
  • Vein of Galen malformations are congenital high-flow vascular malformations that often present with heart failure, hydrocephalus, developmental delay, and intracranial hemorrhage.[ncbi.nlm.nih.gov]
  • We studied two siblings affected by severe developmental delay and liver dysfunction.[ncbi.nlm.nih.gov]
Chest Pain
  • Recently, he developed a chest pain and underwent adenosine stress myocardial perfusion single photon emission CT (SPECT). During the adenosine stress, he felt severe chest pain and ST elevation on electrocardiogram.[ncbi.nlm.nih.gov]
  • Subsequently, the patient developed chest pain and ST segment elevation in the inferior leads that resolved with sublingual nitroglycerin. This report showed a case of coronary spasm secondary to the administration of adenosine.[ncbi.nlm.nih.gov]
  • Heart disease : ATP can cause reduced blood flow to the heart and chest pain. It might worsen symptoms in patients with heart diseases such as chest pain and heart attack.[webmd.com]
  • pain, flushing and dyspnoea).[bestbets.org]
Auditory Hallucination
  • ADA levels were found to be higher among patients, and revealed a possible link between evening rise and severity of auditory hallucinations as well as morning rise and severity of avolition-apathy in patients with schizophrenia.[ncbi.nlm.nih.gov]
Slurred Speech
  • The proband, a 37-year-old man presented with bladder incontinence, slurred speech, dysmetria in all limbs, difficulties in balancing, and gait ataxia.[ncbi.nlm.nih.gov]
Dysmetria
  • The proband, a 37-year-old man presented with bladder incontinence, slurred speech, dysmetria in all limbs, difficulties in balancing, and gait ataxia.[ncbi.nlm.nih.gov]
Intracranial Hemorrhage
  • Vein of Galen malformations are congenital high-flow vascular malformations that often present with heart failure, hydrocephalus, developmental delay, and intracranial hemorrhage.[ncbi.nlm.nih.gov]
Gait Ataxia
  • The proband, a 37-year-old man presented with bladder incontinence, slurred speech, dysmetria in all limbs, difficulties in balancing, and gait ataxia.[ncbi.nlm.nih.gov]

Treatment

  • The use of adenosine-induced cardiac standstill for treatment of vein of Galen malformations has not been previously described in neonates.[ncbi.nlm.nih.gov]
  • We anticipate these results will aid in drug design, drug delivery and treatment options for neurological diseases such as AD, Parkinson's disease, multiple sclerosis and cancers of the CNS.[ncbi.nlm.nih.gov]
  • In the light of the results, adenosine has no statistically superiority to minoxidil in the treatment of androgenetic alopecia according to recovery rates.[ncbi.nlm.nih.gov]
  • Bergfeld, Androgenetic Alopecia: An Evidence-Based Treatment Update, American Journal of Clinical Dermatology, 15, 3, (217), (2014).[doi.org]
  • Improved treatments for chronic hepatitis C virus (HCV) infection are needed due to the suboptimal response rates and deleterious side effects associated with current treatment options.[ncbi.nlm.nih.gov]

Prognosis

  • Evaluation of A1R by MPDX-PET may be useful for predicting prognosis and understanding the compensatory and reorganization processes in hemianopia caused by organic brain damage.[ncbi.nlm.nih.gov]
  • Prognosis Prognosis depends on the severity of the disease. Without treatment, SCID due to ADA deficiency that presents in infancy usually results in early death.[orpha.net]
  • The level of oral (O)SCC differentiation does not correlate with prognosis, while tumor colonization by microorganisms and chronic inflammation may well contribute to OSCC pathogenesis.[jimmunol.org]

Etiology

  • Etiology SCID due to ADA deficiency is caused by mutations in the ADA gene (20q13.11). The extraimmune manifestations are caused by toxic levels of purine metabolites that result from the deficiency of ADA.[orpha.net]
  • May be useful for diagnosis and treatment of stable, regular monomorphic wide-complex tachycardias † if the etiology of the rhythm cannot be determined. 400 401 Not effective in terminating arrhythmias not due to reentry involving the AV or sinus node[drugs.com]

Epidemiology

  • He has since completed further training in emergency medicine, clinical toxicology, clinical epidemiology and health professional education.[lifeinthefastlane.com]
  • Summary Epidemiology SCID due to ADA deficiency accounts for 10-15% of all cases of SCID. Its annual incidence is estimated to be between 1/200,000 and 1/1,000,000 live births. Both males and females are affected.[orpha.net]
  • [Article in Russian; Abstract available in Russian from the publisher] Abstract Large-scale epidemiological and clinical studies have demonstrated the efficacy of metformin in oncology practice.[ncbi.nlm.nih.gov]
  • Top Your questions, contributions and commentaries will be answered by the lecturer or experts on the subject in the Prevention and Epidemiology list. Please fill in the form (in Spanish, Portuguese or English) and press the "Send" button.[fac.org.ar]
  • Filoviruses: A Compendium of 40 Years of Epidemiological, Clinical, and Laboratory Studies (Springer, 2008) 2. Bausch, D. G. et al. Assessment of the risk of Ebola virus transmission from bodily fluids and fomites. J. Infect. Dis. 196 (suppl. 2).[doi.org]
Sex distribution
Age distribution

Pathophysiology

  • These intense studies allowed a deeper knowledge of the nature and, moreover, of the pathophysiological roles of all the adenosine receptor subtypes.[ncbi.nlm.nih.gov]
  • Adenosine is a key myocardial metabolite that elicits coronary vasodilation in a variety of pathophysiological conditions. We examined the mechanism of adenosine-induced vasodilation in coronary arterioles from patients with heart disease.[ncbi.nlm.nih.gov]
  • BACKGROUND: Platelets are important for effective hemostasis and considered to be involved in pathophysiological processes, e.g. in cardiovascular diseases.[ncbi.nlm.nih.gov]
  • These data provide further insights into the role of purinergic signaling in the pathophysiology of renal IRI. Copyright 2017 Elsevier Ltd. All rights reserved. KEYWORDS: A(2B)R; AMP; Adenosine; Docking; G(q) activation; Homology model[ncbi.nlm.nih.gov]
  • Kanami Orihara, Nyla Dil, Vidyanand Anaparti and Redwan Moqbel, What’s new in asthma pathophysiology and immunopathology?, Expert Review of Respiratory Medicine, 4, 5, (605), (2010). Wan-chun Sun, James N. Moore, David J. Hurley, Michel L.[doi.org]

Prevention

  • However, the patients were significantly more satisfied with adenosine because of faster prevention of hair loss and appearance of the newly grown hairs.[ncbi.nlm.nih.gov]
  • Treatment of DENV-infected mice with NITD008 suppressed peak viremia, reduced cytokine elevation, and completely prevented the infected mice from death.[ncbi.nlm.nih.gov]
  • In conclusion, activation of A2b receptor could prevent high glucose-induced apoptosis of H9C2 cells in vitro to a certain extent by activating PI3K/Akt signaling.[ncbi.nlm.nih.gov]
  • The recommended dose may be increased in patients on theophylline, since methylxanthines prevent binding of adenosine at receptor sites.[en.wikipedia.org]

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