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Adenosine
Adenocard Injection

Images

WIKIDATA, Public Domain
WIKIDATA, CC0 1.0
WIKIDATA, Public Domain

Presentation

Our subsequent management and follow-up is presented. [ncbi.nlm.nih.gov]

Entire Body System

  • Intravenous Administration

    For that reason, asystole was chemically induced by the intravenous administration of adenosine. The surgery was successful, and the patient was discharged from the hospital on the 10th postoperative day. [ncbi.nlm.nih.gov]

    administration in people with neuropathic pain. [clinicaltrials.gov]

    Imaging of adenosine bolus transit following intravenous administration: insights into antiarrhythmic efficacy. Heart 1999;82(2):163-9. PubMed [ PMID: 10409529 ] PDF Lopez-Palop R, Saura D, Pinar E, et al. [aliem.com]

    Comparison between fractional flow reserve (FFR) measurements after intravenous (i.v.) and intracoronary (i.c.) administration of adenosine. A, Correlation between mean FFR after i.v. (FFR iv ) and i.c. (FFR ic ) administration of adenosine. [circinterventions.ahajournals.org]

    DOSAGE AND ADMINISTRATION For rapid bolus intravenous use only. Adenosine injection should be given as a rapid bolus by the peripheral intravenous route. [drugs.com]

Cardiovascular

  • Chest Pain

    Recently, he developed a chest pain and underwent adenosine stress myocardial perfusion single photon emission CT (SPECT). During the adenosine stress, he felt severe chest pain and ST elevation on electrocardiogram. [ncbi.nlm.nih.gov]

    Heart disease : ATP can cause reduced blood flow to the heart and chest pain. It might worsen symptoms in patients with heart diseases such as chest pain and heart attack. [webmd.com]

    pain, flushing and dyspnoea). [bestbets.org]

Workup

T Wave

  • T Wave Inversion

    Presenting electrocardiogram (ECG) showed an old left bundle branch block and T-wave inversions in lateral leads (QTc 494ms) with no significant electrolyte abnormalities. [ncbi.nlm.nih.gov]

Treatment

Intravenous boluses of adenosine were injected as an attempt to slow down the arteriovenous shunting of a VGAM prior to endovascular treatment. [ncbi.nlm.nih.gov]

Prognosis

Prognosis Prognosis depends on the severity of the disease. Without treatment, SCID due to ADA deficiency that presents in infancy usually results in early death. [orpha.net]

The level of oral (O)SCC differentiation does not correlate with prognosis, while tumor colonization by microorganisms and chronic inflammation may well contribute to OSCC pathogenesis. [jimmunol.org]

The objective of a cardiac stress test is to evaluate the patient for significant, stable coronary artery disease and/or prognosis through the induction of ischemia. [ncbi.nlm.nih.gov]

Etiology

Etiology SCID due to ADA deficiency is caused by mutations in the ADA gene (20q13.11). The extraimmune manifestations are caused by toxic levels of purine metabolites that result from the deficiency of ADA. [orpha.net]

May be useful for diagnosis and treatment of stable, regular monomorphic wide-complex tachycardias † if the etiology of the rhythm cannot be determined. 400 401 Not effective in terminating arrhythmias not due to reentry involving the AV or sinus node [drugs.com]

Epidemiology

He has since completed further training in emergency medicine, clinical toxicology, clinical epidemiology and health professional education. [lifeinthefastlane.com]

Summary Epidemiology SCID due to ADA deficiency accounts for 10-15% of all cases of SCID. Its annual incidence is estimated to be between 1/200,000 and 1/1,000,000 live births. Both males and females are affected. [orpha.net]

[Article in Russian; Abstract available in Russian from the publisher] Abstract Large-scale epidemiological and clinical studies have demonstrated the efficacy of metformin in oncology practice. [ncbi.nlm.nih.gov]

There is fairly convincing prospective epidemiological evidence of a protective effect of caffeine against Parkinson's disease! Specific A2A ant agonists may be useful in Parkinson's disease. [anaesthetist.com]

Pathophysiology

Adenosine is a key myocardial metabolite that elicits coronary vasodilation in a variety of pathophysiological conditions. We examined the mechanism of adenosine-induced vasodilation in coronary arterioles from patients with heart disease. [ncbi.nlm.nih.gov]

Adenosine and its receptors, pathophysiological significance and therapeutic opportunities. [ki.se]

Their effects in various cells are diverse and depend on the particular receptor. 4 Pathophysiology Cholera toxin blocks the GTPase enzyme which results in the constant stimulation of adenylyl cyclase which brings about permanently increased cAMP levels [flexikon.doccheck.com]

Prevention

Adenosine prevents firing of new impulses and also prevents conduction of the impulse via the AV node. Thus it is active in SVT. Adenosine receptors The normal level of adenosine in blood ranges between 0.04 and 0.2 micromoles. [news-medical.net]

However, the patients were significantly more satisfied with adenosine because of faster prevention of hair loss and appearance of the newly grown hairs. [ncbi.nlm.nih.gov]

Thus, in regard to stress or injury, the function of adenosine is primarily that of cytoprotection preventing tissue damage during instances of hypoxia, ischemia, and seizure activity. [medchemexpress.com]

ATP might also prevent changes in energy metabolism that cause weight loss in people with advanced cancer. [webmd.com]

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