[…] tubular structures limited by two or more layers of cells, often presenting a mucinous content. [jscisociety.com]

The mucosal epithelium presents with severe dysplasia or carcinoma in situ. [jomfp.in]

Due to its disputed pathophysiology, ambiguity of presentation, and lack of definitive clinical research, cASC is a commonly misdiagnosed skin lesion. [mdedge.com]

Carbohydrate antigen (CA) 19-9 on presentation was 255 U/mL ( FIG. 1. [liebertpub.com]

ASC presented as liver abscess is extremely rare 4 ). [kjim.org]

• Weight Loss

  Here, we present the case of a 50-year-old male, who complained of abdominal pain and weight loss over a 3-month period of time. [karger.com]

  TABLE Clinical and pathological characteristics of the four patients Age (years) 55 66 67 80 Gender Male Male Male Male Presentation Incidental ultrasonographic nodule Weight loss, jaundice, pruritus, acholia and choluria Dyspepsia, weight loss and vomits [scielo.br]

  A review of systems was negative for pain, pruritus, bleeding, fever, unexplained weight loss, and night sweats. [mdedge.com]

  The duration of symptoms prior to presentation was 4.3 3.9 months, and symptoms included abdominal pain and weight loss in 5 of the 6 patients, nausea and vomiting in 3 patients, and anorexia and jaundice in 2 patients. [jamanetwork.com]

  The initial symptoms are commonly abdominal pain, fever, weight loss and jaundice. Preoperative diagnosis is extremely difficult. In our case, preoperative diagnosis was peripheral cholangiocarcinoma by percutaneous liver biopsy. [kjim.org]

• Fever

  In December 1982, a 35-year-old white homosexual man developed fever, night sweats, and a nonproductive cough. In April 1983, he developed pain in his left shoulder. A roentgenogram of the shoulder showed lytic changes in FULL TEXT [annals.org]

  However, fever and abdominal pain induced by cholangitis were reported 2, 3 ). ASC presented as liver abscess is extremely rare 4 ). [kjim.org]

  A review of systems was negative for pain, pruritus, bleeding, fever, unexplained weight loss, and night sweats. [mdedge.com]

  Follow-up Among the patients with cephalic tumors, one went back to emergency room one month after surgery, with fever and generalized malaise, diagnosed with pancreatic fistula; he was hospitalized for 20 days, with antibiotic therapy, until clinical [scielo.br]

• Nausea

  Case Report A 50-year-old Caucasian male with no known past medical history presented to the emergency room with nonspecific complaints of nausea, non-radiating right lower quadrant abdominal pain of 1 week duration which was intermittent, 7/10 in severity [karger.com]

  The patients with the longest duration of symptoms had nonspecific symptoms of bloating and nausea. [nature.com]

  The duration of symptoms prior to presentation was 4.3 3.9 months, and symptoms included abdominal pain and weight loss in 5 of the 6 patients, nausea and vomiting in 3 patients, and anorexia and jaundice in 2 patients. [jamanetwork.com]

• Odynophagia

  Other tumor-related symptoms include odynophagia, otalgia, tongue numbness, bleeding and weight loss. [7] Till now, very few cases have been reported in the floor of the mouth. [jomfp.in]

• Ulcer

  The lesions may ulcerate and cause scarring of skin. [dovemed.com]

  Carcinoma and ulcerative colitis: prognosis. Gastroenterology. 1960;39:385-393. 9. ichelassi F, Montag AG, Block GE. Adenosquamous-cell carcinoma in ulcerative colitis. Report of a case. [gastroenterologyandhepatology.net]

  Ulcer with irregular border F i g u r e 3. Orthpantamogram showed no boney involvement F i g u r e 4. [pubs.sciepub.com]

  […] foci Mixture may be intermingled or discrete foci Must not involve anal squamous mucosa Some require location 5-7 cm above dentate line Anal squamous carcinomas frequently extend into the rectum May be associated with inflammatory intestinal disorders Ulcerative [surgpathcriteria.stanford.edu]

  A raised, red, nontender, ulcerated plaque with slight exudate and gelatinous texture on the right bicep. Figure 2. [mdedge.com]

• Sweating

  In December 1982, a 35-year-old white homosexual man developed fever, night sweats, and a nonproductive cough. In April 1983, he developed pain in his left shoulder. A roentgenogram of the shoulder showed lytic changes in FULL TEXT [annals.org]

  A review of systems was negative for pain, pruritus, bleeding, fever, unexplained weight loss, and night sweats. [mdedge.com]

  The squamous cells will often line ducts that are structurally analogous to the acrosyringium of an eccrine sweat gland. One might also find atypical epithelial ‘ pearls ‘ with enlarged hyperchromatic nuclei, with large, prominent nucleoli. [breast-cancer.ca]

• Skin Lesion

  Other factors that may influence its development include skin tanning, radiation treatment for other reasons, previous burn injuries, and exposure to coal tar and arsenic Adenosquamous Carcinoma of Skin may appear as skin lesions, commonly on sun-exposed [dovemed.com]

  Due to its disputed pathophysiology, ambiguity of presentation, and lack of definitive clinical research, cASC is a commonly misdiagnosed skin lesion. [mdedge.com]

• Night Sweats

  In December 1982, a 35-year-old white homosexual man developed fever, night sweats, and a nonproductive cough. In April 1983, he developed pain in his left shoulder. A roentgenogram of the shoulder showed lytic changes in FULL TEXT [annals.org]

  A review of systems was negative for pain, pruritus, bleeding, fever, unexplained weight loss, and night sweats. [mdedge.com]

• Papule

  Primary cutaneous adenosquamous carcinoma (cASC) is an aggressive subtype of squamous cell carcinoma that was first described in 1985. 1 It typically presents as an erythematous, indurated, keratotic papule or plaque with a predilection for the face, [mdedge.com]

  Adenosquamous carcinoma has typically been described as an indurated, erythematous keratotic papule or plaque, which occurs on the head or neck of an elderly patient who has a history of actinic damage. [jamanetwork.com]

• Otalgia

  Other tumor-related symptoms include odynophagia, otalgia, tongue numbness, bleeding and weight loss. [7] Till now, very few cases have been reported in the floor of the mouth. [jomfp.in]

• Prostatic Disease

  Prostate Cancer and Prostatic Disease, 2012. doi: 10.1038/pcan.2012.4. 5. Mazzucchelli R, Lopez-Beltran A, Cheng L, et al. Rare and unusual histological variants of prostatic carcinoma: clinical significance. [bjuinternational.com]

As a result, an extensive metastatic workup was performed. Bone scan revealed multiple metastatic sites including the patient’s right rib, pubic symphysis, and iliac crest. [bjuinternational.com]

After a complete workup, the patient was diagnosed with stage IV poorly differentiated ASC of colon. He was started on palliative chemotherapy with fluorouracil and cisplatin. [karger.com]

• Atelectasis

  A chest radiograph demonstrated normal heart size and pulmonary vasculature with mild bibasilar atelectasis and no areas of consolidation. [mdedge.com]

• Human Papillomavirus

  High risk human papillomavirus was detected in 148/211 (70%) cases with valid human papillomavirus results from tumour tissues. [bmj.com]

  Recently, it was also proven that human papillomavirus (HPV) is an important etiological agent in H and N carcinomas particularly in the oropharynx and nasal cavity. High-risk HPV (HPV-16) has been detected in about 80% of SCC cases. [jomfp.in]

  Additionally, the colonic malignancy was positive for p16 and negative for high-risk human papillomavirus. [gastroenterologyandhepatology.net]

  This may also contribute to the formation of the skin cancer Scientific research has indicated that the human papillomavirus along with other risk factors, such as sun-exposure, skin color, and an advancing age, seem to greatly multiply the chance of [dovemed.com]

Median overall survival (OS) for 14 eligible patients with multi-line EGFR-TKIs treatment was 42.1 months (95% CI, 15.7-68.5 months), compared to median OS of patients without third-generation treatment (25.1 months, 95% CI, 10.7-39.4) months. [oncologypro.esmo.org]

1 Management Of Anemia Under RadioChemotherapy (MARCH): An Open, Randomized Multicenter Study Of The Effect Of NeoRecormon On Treatment Outcome In Patients With Advanced Cervical Cancer Stage IIB -IVA Treated With Primary Simultaneous Radiochemotherapy [malacards.org]

[…] carcinoma of content cachedadenosquamous lung is rare subtype Similardefinition of nonsmall adenosquamouscarcinoma cached Health sciences, volume, issue, topic cachedcarcinoma asc is type adenosquamous-breast- -year survival a doi pdfjournal of its treatments [laboratoriorojan.com.br]

The treatment measures may include: In most cases, a wide surgical excision and removal of the entire tumor is the preferred treatment option. [dovemed.com]

The studies of crizotinib in the treatment of patients with ASC are very limited. Immune checkpoint blockade therapy may be a potential treatment choice for ASC patients. [dovepress.com]

If metastasis (such as to the local lymph nodes) is observed, then the prognosis is guarded or unpredictable Tumors in their early stage with complete excisional treatment typically have good prognosis In cases of metastasis, its prognosis depends upon [dovemed.com]

Prognosis The prognosis is inferior to that for either squamous cell carcinoma or adenocarcinoma 1,2,5,6. References 0 Tumours of the Lung, Pleura, Thymus and Heart. WHO Classification of Tumours. [e-immunohistochemistry.info]

Pulmonary adenosquamous carcinoma has a worse prognosis than either adenocarcinoma or squamous carcinoma. Only one of the two components may be seen in metastatic sites. [pathologyoutlines.com]

prognosis in ASC patients. [oncotarget.com]

We have summarized these reports, including the clinical course and final prognosis of ASC of the AmV, in Table 2 [ 1 – 4 ]. ASC of the AmV is a virulent disease with a worse prognosis than that of adenocarcinoma. [wjso.biomedcentral.com]

Use code specific for location of tumor C34.90 Malignant neoplasm of unspecified part of unspecified bronchus or lung Sites Tends to arise peripherally but may be central Pathophysiology More aggressive than "pure" carcinomas when matched for stage Etiology [pathologyoutlines.com]

At present, any evidence-based conclusions regarding their etiology or treatment remain elusive, thus illustrating the need for further research. References 1. l-Shehri A, Silverman S, King KM. Squamous cell carcinoma of the pancreas. [gastroenterologyandhepatology.net]

Chronic inflammation of the bile duct, usually in association with infection and/or stones, has been proposed as an etiologic factor 2 ). Such continuous irritations induce metaplastic changes in the biliary epithelium and lead to neoplasia 3 ). [kjim.org]

(Etiology) Adenosquamous Carcinoma of Skin is caused when skin cells (the keratinocytes that form the epidermis) are burnt or damaged from prolonged (frequently severe) exposure to the ultraviolet component of the sun, over many decades The source of [dovemed.com]

Recently, it was also proven that human papillomavirus (HPV) is an important etiological agent in H and N carcinomas particularly in the oropharynx and nasal cavity. High-risk HPV (HPV-16) has been detected in about 80% of SCC cases. [jomfp.in]

"Adenosquamous carcinoma of the pancreas: a population based clinical outcomes studies involving 700 patients from the Surveillance, Epidemiology, and End Results (SEER) database (1973-2010)". [en.wikipedia.org]

Epidemiology Up to 4% of lung carcinomas are of adenosquamous type 1,2,3,5. The tumour is more common in men 4 and here is a strong association with smoking 4. Radiology Most tumours are peripheral. [e-immunohistochemistry.info]

Cooke et al. [ 8 ] identified 872 ASC patients who underwent surgery from the Surveillance, Epidemiology, and End Results (SEER) database (1998–2002), and found that ASC had a worse prognosis than ADC and SCC. [oncotarget.com]

Literature on ASC is scare and mostly consists of small case series.[ 3, 4, 5, 6, 7 ] Only recently did larger case series emerge.[ 8, 9 ] The purpose of this review is to summarize the existing data on epidemiology, pathogenesis, histopathology, clinical [content.sciendo.com]

[…] metaplasia as well as squamous cell carcinoma with pseudoglandular features ICD coding Use code specific for location of tumor C34.90 Malignant neoplasm of unspecified part of unspecified bronchus or lung Sites Tends to arise peripherally but may be central Pathophysiology [pathologyoutlines.com]

Due to its disputed pathophysiology, ambiguity of presentation, and lack of definitive clinical research, cASC is a commonly misdiagnosed skin lesion. [mdedge.com]

In the case report by Adebajo and coworkers, immunohistochemical staining of the patient’s tumor was strongly positive for CK5/6 but negative for CK7 and CK20. 1 Adebajo and colleagues provided a brief but concise summary of the known pathophysiologic [gastroenterologyandhepatology.net]

With the nine-valent human papillomavirus vaccine, which covers five additional virus types, additional prevention of ASC and RICC could be expected in future. [bmj.com]

A few methods to prevent Adenosquamous Carcinoma of Skin include: Avoid prolonged and chronic exposure to the sun. [dovemed.com]

Abstract Overall, colorectal cancer is the third most commonly diagnosed cancer in both men and women, meaning that it is one of the more widely recognized preventable cancers. [karger.com]

The involvement of PI 3-K/Akt-dependent up-regulation of Mcl-1 in the prevention of apoptosis of Hep3B cells by interleukin-6. Oncogene 2001; 20:677-85. [pancreas.imedpub.com]