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Adenoviridae

Adenovirus


Presentation

  • Phylogenetic trees of the whole-genome, penton base, and fiber knob regions are presented in the top row with the hexon and its parts, “loop 1” and “conserved,” presented in the bottom row. All were generated after sequence alignments.[doi.org]
  • The presenting symptoms were varied in all of the groups studied and no particular presenting factor predicted the risk of associated haematuria. Haematuria is a frequent presentation requiring nephrological follow up.[adc.bmj.com]
  • This article presents a proposal for the establishment of a new adenovirus genus to accommodate certain bovine, ovine, and avian adenoviruses with special characteristics which differentiate them from members of the existing genera Mastadenovirus and[hungary.pure.elsevier.com]
  • Since the upper respiratory tract is most common, kids usually present with fever, nasal congestion, cough and sore throat.[nationwidechildrens.org]
  • Respiratory syncytial virus (RSV) and human adenovirus were the most common respiratory viruses detected from nasopharyngeal aspirates of 450 children aged younger than 5 years who presented with a lower respiratory tract infection at a Cairo hospital[healio.com]
Hyperthermia
  • Bo-Kyeong Jung, Yeon Kyung Lee, JinWoo Hong, Hamidreza Ghandehari and Chae-Ok Yun, Mild Hyperthermia Induced by Gold Nanorod-Mediated Plasmonic Photothermal Therapy Enhances Transduction and Replication of Oncolytic Adenoviral Gene Delivery, ACS Nano,[doi.org]
Recurrent Upper Respiratory Infections
  • The researcher endorsed a history of recurrent upper respiratory infections, and did not regard the illness as related to the titi monkey outbreak.[doi.org]
Ulcer
  • For example, ulcers were once thought to be the result of stress, but researchers eventually implicated bacteria, H. pylori, as a cause.[scienceblog.com]
Large Ears
  • 1 P greater horseshoe bat 1 P P greater mouse-eared bat M78-28 greater mouse-eared bat 1 P greater short-nosed fruit bat NEW China g reat roundleaf bat grey long-eared bat P P Hungary heart-nosed bat NEW Kenya Horsfield's bat Kuhl's pipistrelle 1 P large-eared[vmri.hu]
Fracture
  • FP stands for fracture plane in freeze etching. (From Brown DT, Westphal M, Burlingham BT et al.: Structure and composition of the adenovirus type 2 core. J. Virol. 16:366, 1975, with permission.)[web.archive.org]
Flaccid Paralysis
  • HAdV-C57 was isolated from the feces of a healthy child as part of an acute flaccid paralysis surveillance program (12 December 2001; Baku, Azerbaijan). It was serotyped by SN and provided an ambiguous typing result. Genome sequencing.[doi.org]

Workup

  • A routine microbiological workup for infectious causes of the outbreak, including bacterial, mycoplasma, and fungal cultures, was negative.[doi.org]
Human Herpesvirus 6
  • Leveque N, Boulagnon C, Brasselet C, Lesaffre F, Boutolleau D, Metz D, Fornes P, Andreoletti L (2011) A fatal case of Human Herpesvirus 6 chronic myocarditis in an immunocompetent adult. J Clin Virol 52:142–145 CrossRef PubMed Google Scholar 7.[doi.org]

Treatment

  • Other treatment, depending on the symptoms, may include intravenous fluids, oxygen, and breathing treatments. How Long Do Adenovirus Infections Last? Most adenovirus infections last from a few days to a week or two.[kidshealth.org]
  • What is the best treatment? There are no FDA-approved agents for the treatment of adenovirus infections. The most effective, clinically available antiviral agent active against adenovirus is cidofovir.[infectiousdiseaseadvisor.com]
  • Diagnosis and Treatment Although tests can detect adenovirus, most diagnoses are made on the basis of symptoms. Treatment for adenovirus means managing symptoms until the infection clears.[intermountainhealthcare.org]
  • Testing helps keep track of the effectiveness of active treatment and can be used to monitor for relapse after treatment.[biomerieux-diagnostics.com]
  • Kajon’s team tested college students at one campus during the severe 2014-15 influenza epidemic and found 13 out of 168 students who came in for flu treatment had adenovirus infections.[nbcnews.com]

Prognosis

  • The prognosis declines as the severity of disease increases.[medicinenet.com]
  • Prognosis The prognosis of adenovirus infection is generally good in immunocompetent hosts, but mortality rates may be as high as 70% in immunocompromised individuals.[emedicine.medscape.com]
  • Hepatic disease : Adenovirus hepatitis has the worst prognosis in liver transplant recipients but may also occur in HSCT patients.[infectiousdiseaseadvisor.com]

Etiology

  • The difference in testing methods should be considered when designing surveillance studies “to estimate the burden of viral etiologies of respiratory diseases,” the researchers said.[healio.com]
  • Attempts to isolate the virus from previous sea lion hepatitis cases were unsuccessful, but as the hepatitis had morphologic features resembling canine infectious hepatitis, and since the virus has a wide host range, it was thought that perhaps the etiologic[doi.org]
  • We analyzed 59 norovirus-positive cases with known etiology and 66 norovirus-negative cases with unknown etiology from eight different norovirus outbreaks for the presence of HAdV-52 via PCR.[doi.org]
  • […] gross and histo Infectious canine hepatitis immunity Recovered are immune Maternal antibodies until 9 to 12 weeks Inactivated and attenuated virus vaccines Causes mild subclinical interstitial nephritis Canine infectious tracheobronchitis - kennel cough etiologic[quizlet.com]
  • “With the exception of infectious diseases, no other chronic disease in history has spread so rapidly, and the etiological factors producing this epidemic have not been clearly identified.”[scienceblog.com]

Epidemiology

  • Other epidemiological feature was as follows: EAd were detected throughout the year. The predominant serotype was Ad40 during 1980-1985, while Ad41 were observed after 1986. EAd were detected most frequently from the children aged 0-3 years.[doi.org]
  • RETROTRANSPOSONS OF FUNGI RETROVIRAL ONCOGENES RETROVIRUSES TYPE D RETROVIRIDAE THE GYPSY PARADIGM RHABDOVIRUSES RHABDOVIRIDAE RHINOVIRUSES PICORNAVIRIDAE Geographic and Seasonal Distribution Genetics and Evolution Serological Relationship and Variability Epidemiology[books.google.es]
  • In the present study, we identified AdVs in NHPs living in their natural habitats, and through the combination of phylogenetic analyses and information on the habitats and epidemiological settings, we detected possible horizontal transmission events between[edoc.rki.de]
  • Department of Virology and Epidemiology, Baylor College of Medicine, Houston, Texas. Reichmann, M. E. Formerly, Department of Microbiology, University of Illinois at Urbana-Champaign, Urbana, Illinois.[accessscience.com]
Sex distribution
Age distribution

Pathophysiology

  • Pathophysiology Adenovirus is a double-stranded DNA virus that measures 70-90 nm and that has an icosahedral capsid.[emedicine.medscape.com]
  • There is little information about the epidemiology, pathophysiology and the usual route of infection of Ad-36. Human adenoviruses are associated with infection of the respiratory tract, gastrointestinal tract, and conjunctiva.[doi.org]

Prevention

  • Kajon believes it should be more widely available, “This is a vaccine-preventable disease,” she said. “A life is a life. Losing a loved one to viral pneumonia when you know it could have been prevented is hard.”[nbcnews.com]
  • And even if more doctors checked for the flu-like bug known as adenovirus, the vaccine to prevent it remains licensed for military use only.[eu.usatoday.com]
  • When adenovirus infects the eyes, antibiotic eyedrops may be used to prevent secondary bacterial infection, and gastrointestinal involvement may be treated with medication to control nausea and vomiting, along with fluids to prevent or treat dehydration[nationwidechildrens.org]
  • Kumthekar R, Berul CI (2018) Implantable cardioverter defibrillators and biventricular pacing in pediatric dilated cardiomyopathy: preventing death and delaying heart transplant. Prog Pediatr Cardiol 49:38–42 CrossRef Google Scholar 5.[doi.org]

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