Phylogenetic trees of the whole-genome, penton base, and fiber knob regions are presented in the top row with the hexon and its parts, “loop 1” and “conserved,” presented in the bottom row. All were generated after sequence alignments. [doi.org]

The presenting symptoms were varied in all of the groups studied and no particular presenting factor predicted the risk of associated haematuria. Haematuria is a frequent presentation requiring nephrological follow up. [adc.bmj.com]

The patients presented with sudden onset respiratory distress that progressed rapidly to respiratory failure and death. [ncbi.nlm.nih.gov]

• Inflammation

  […] or infection Inflammation of stomach and intestines Neurologic disease (conditions that affect the brain and spinal cord) Adenoviruses can cause mild to severe illness, though serious illness is less common. [cdc.gov]

  Angela Murphy – Role of macrophage-induced inflammation in colon cancer Carole Oskeritzian – Targeting skin inflammation in atopic dermatitis Gregorio Gomez – Effect of resveratrol on IgE-dependent mast cell functions in allergies Dev Karan – Targeting [pathmicro.med.sc.edu]

  In vivo, inflammation induced by the virus was dramatically greater than that by adenovirus type 37, a major eye pathogen, possibly due to a novel alternate ligand, Tyr-Gly-Asp (YGD), on the penton base protein. [ncbi.nlm.nih.gov]

  The viruses cause a wide range of illnesses and symptoms such as Colds Sore throat (pharyngitis) Bronchitis Pneumonia Gastroenteritis and diarrhea Pink eye (conjunctivitis) Bladder inflammation or infection (cystitis) Inflammation of stomach and intestines [quidel.com]

  Enteric adenoviruses, types 40 and 41, are known to cause gastroenteritis (an inflammation of the stomach and intestines), particularly in children. [verywellhealth.com]

• Asymptomatic

  Asymptomatic respiratory or GI viral shedding may continue for months, or even years. [msdmanuals.com]

  Infections may be asymptomatic or result in a variety of diseases. [decs.bvs.br]

  Some types are capable of establishing persistent asymptomatic infections in tonsils, adenoids, and intestines of infected hosts, and shedding can occur for months or years. [certest.es]

• Military Personnel

  An oral vaccine can reduce incidence of lower respiratory disease but is available only for military personnel. NOTE: This is the Professional Version. [msdmanuals.com]

  Food and Drug Administration in March 2011, for use only in U.S. military personnel who may be at higher risk for infection from these two adenovirus types. For more information about the vaccine, see Adenovirus Vaccine Information Statement (VIS). [cdc.gov]

  Food and Drug Administration in March 2011, for U.S. military personnel only. The vaccine is not available to the general public. [quidel.com]

• Pneumonia

  The mainstay of treatment for patients with severe adenovirus pneumonia is still supportive, with the use of antivirals not apparently effective. [ncbi.nlm.nih.gov]

• Cough

  Adenovirus can cause a cough that sounds like whooping cough (pertussis). Gastroenteritis is an infection of the stomach and intestines. Symptoms include diarrhea, vomiting, belly pain, and fever. [kidshealth.org]

  Symptoms Each type of adenovirus can affect you differently: Bronchitis: Cough, runny nose, fever, chills Colds and other respiratory infections: Stuffy and runny nose, cough, sore throat, and swollen glands Croup: Barking cough, trouble breathing, high-pitched [webmd.com]

  DHS: Is it the flu, a cold, or whooping cough?, P-02263: Flyer outlining the differences between the flu, a cold, and whooping cough. [dhs.wisconsin.gov]

• Common Cold

  Photo Credit: Pathology Laboratory Medicine 2016 Adenoviruses are one of the respiratory viruses that can cause the common cold. [health.hawaii.gov]

  Adenoviruses are a group of viruses that cause respiratory (breathing) illnesses, such as a common cold, conjunctivitis (an infection in the eye), croup, bronchitis, bronchiolitis (inflammation of the lower airways), and pneumonia. [childrenshospital.org]

  Adenoviruses can cause a wide range of illnesses such as Common cold Sore throat Bronchitis (a condition that occurs when the airways in the lungs become filled with mucus and may spasm, which causes a person to cough and have shortness of breath) Pneumonia [cdc.gov]

  Symptoms of respiratory illness caused by Adenovirus infection range from the common cold syndrome to pneumonia, croup, and bronchitis. [certest.es]

• Vomiting

  IMPORTANCE The nonenveloped human adenovirus 41 causes diarrhea, vomiting, dehydration, and low-grade fever mainly in children under 2 years of age. [ncbi.nlm.nih.gov]

  Babies and children with vomiting and diarrhea who can't drink enough liquids may need treatment for dehydration. [kidshealth.org]

  Kids lose fluids from fever, vomiting, and diarrhea. They can get dehydrated. Water or 100% fruit juice are the best choices to keep kids hydrated. You might also try a children's solution that has electrolytes. Clear congestion. [webmd.com]

• Nausea

  A 59-year-old man with T-cell prolymphocytic leukemia on alemtuzumab presented with neutropenic fever, intermittent nausea, and multiple ill-defined low attenuation foci in the liver on abdominal computed tomography scan which were suspicious for metastatic [ncbi.nlm.nih.gov]

  The incidence of vomiting, nausea and respiratry symptoms was higher in Ad41 associated infections than Ad40. [doi.org]

  Most of the children affected are five years old or younger and have had symptoms of gastroenteritis illness - diarrhoea and nausea - followed by jaundice or yellowing of the skin and eyes (a sign that the liver is struggling). [bbc.com]

  Symptoms include fever, headache, nausea and vomiting, stiff neck, and confusion. Is Adenovirus Contagious? Adenovirus is highly contagious. [kidshealth.org]

  When adenovirus infects the eyes, antibiotic eyedrops may be used to prevent secondary bacterial infection, and gastrointestinal involvement may be treated with medication to control nausea and vomiting, along with fluids to prevent or treat dehydration [nationwidechildrens.org]

• Abdominal Pain

  Clinical features Symptoms caused by adenoviruses vary with the serotypes of virus, such as cough, runny nose, sore throat and fever in the respiratory tract; abdominal pain and diarrhoea in the gastrointestinal tract; and eye infection commonly known [chp.gov.hk]

  pain Ear pain Urinary symptoms/hematuria Eye redness and pain Irritative voiding symptoms (bladder involvement) Physical Exam Fever Tonsillar erythema/exudate Cervical lymphadenopathy Otitis media Conjunctivitis Differential Diagnosis Characteristics [unboundmedicine.com]

  The most common adverse events after adenovirus vaccine receipt are headaches, stuffy nose, sore throat, joint pain, abdominal pain, cough, nausea, diarrhea, or fever. [health.mil]

  But symptoms of hepatitis or serious illness can include severe abdominal pain, prolonged fever, jaundice, or yellowing of the skin and eyes, and increased lethargy. These may indicate that you should reach out to a healthcare professional. [healthline.com]

• Severe Abdominal Pain

  But symptoms of hepatitis or serious illness can include severe abdominal pain, prolonged fever, jaundice, or yellowing of the skin and eyes, and increased lethargy. These may indicate that you should reach out to a healthcare professional. [healthline.com]

• Heart Disease

  About 97 million adults in the United States are overweight or obese, according to NIH, and face an increased risk of Type 2 diabetes, coronary heart disease, stroke, gallbladder disease, osteoarthritis, and other health disorders. [biologynews.net]

  […] with heart disease. visualspace / Getty Images Types of Adenoviruses More than 57 have been identified. [verywellhealth.com]

  Related: 27 devastating infectious diseases In humans, adenovirus infections most commonly cause mild respiratory symptoms, but sometimes, the viruses can cause severe disease; people with compromised immune systems, existing respiratory diseases or heart [livescience.com]

  Comparison of the Atkins, Ornish, Weight Watchers, and Zone diets for weight loss and heart disease risk reduction: a randomized trial. JAMA. 2005; 293 :43–53. [ PubMed ] [ Google Scholar ] 8. Padwal RS, Majumdar SR. [ncbi.nlm.nih.gov]

• Jaundice

  Most of the children affected are five years old or younger and have had symptoms of gastroenteritis illness - diarrhoea and nausea - followed by jaundice or yellowing of the skin and eyes (a sign that the liver is struggling). [bbc.com]

  All patients presented with jaundice, or yellowing of the skin, and were tested and diagnosed with hepatitis. Two patients required liver transplants. [uab.edu]

  Causes death with severe extensive hepatocyte damage on post mortem inspection Subacute- fever, conjunctivitis, nasal discharge, abdo pain, petichae of mucosa, leucoponeia, bleeding, DIC, vomiting, bloody di+, jaundice animal can recover- usually slow [quizlet.com]

  “The symptoms of liver dysfunction to look out for in your child are diarrhea, vomiting, jaundice — yellow eyes and yellow skin, pain in the right side of their abdomen — particularly the upper area, fever, and other flu-like symptoms,” he says. [news.llu.edu]

• Dermatitis

  Angela Murphy – Role of macrophage-induced inflammation in colon cancer Carole Oskeritzian – Targeting skin inflammation in atopic dermatitis Gregorio Gomez – Effect of resveratrol on IgE-dependent mast cell functions in allergies Dev Karan – Targeting [pathmicro.med.sc.edu]

  United States 2 Pediatrics, Rush University Medical Center, Chicago, Illinois, United States Correspondence to Dr Kelsey Danley; kelsey_t_danley{at}rush.edu Abstract A 4-month-old boy with a history of muscular ventricular septal defect and atopic dermatitis [casereports.bmj.com]

• Skin Rash

  rash, diarrhea Occurs mostly in children from newborn to 3 years DDx: bacterial pneumonia, RSV, influenza, parainfluenza Acute pharyngoconjunctival fever Spiking fever, headache, pharyngitis, conjunctivitis (typically unilateral), rhinitis, cervical [unboundmedicine.com]

A standard diagnostic workup for children with acute hepatitis should be done locally per treating clinicians. [dph.illinois.gov]

A routine microbiological workup for infectious causes of the outbreak, including bacterial, mycoplasma, and fungal cultures, was negative. [doi.org]

• Intranuclear Inclusion Bodies

  The inclusion bodies showed a positive reaction against rabbit anti-bovine adenovirus serotypes 1, 3, and 7 sera by the immunoperoxidase technique. Ultrastructurally, adonovirus-like particles were demonstrated in intranuclear inclusion bodies. [doi.org]

This protocol facilitates rapid and cost-effective generation of virus-specific TCLs, which appear to provide an effective treatment option. [ncbi.nlm.nih.gov]

Other treatment, depending on the symptoms, may include intravenous fluids, oxygen, and breathing treatments. How Long Do Adenovirus Infections Last? Most adenovirus infections last from a few days to a week or two. [kidshealth.org]

Timely diagnosis and appropriate management are essential to improve the prognosis of adenovirus hepatitis in immunocompromised patients. [ncbi.nlm.nih.gov]

The prognosis declines as the severity of disease increases. [medicinenet.com]

LESSON: Although the most common cause that leads to HUS remains STEC, other etiologies like viral ones that may be responsible for severe enteric infection with progression into HUS should not be neglected. [ncbi.nlm.nih.gov]

The difference in testing methods should be considered when designing surveillance studies “to estimate the burden of viral etiologies of respiratory diseases,” the researchers said. [healio.com]

We analyzed 59 norovirus-positive cases with known etiology and 66 norovirus-negative cases with unknown etiology from eight different norovirus outbreaks for the presence of HAdV-52 via PCR. [doi.org]

Child Child, Preschool China/epidemiology Conjunctivitis/epidemiology Conjunctivitis/etiology* Conjunctivitis/virology DNA, Viral/isolation & purification DNA, Viral/metabolism Female Genotype Humans Infant Infant, Newborn Logistic Models Male Middle [ncbi.nlm.nih.gov]

Weekly Epidemiological Record = Relevé épidémiologique hebdomadaire, 53 (‎11)‎, 79. https://apps.who.int/iris/handle/10665/221792 Revue Weekly Epidemiological Record = Relevé épidémiologique hebdomadaire, 53 (‎11)‎: 79 [apps.who.int]

Epidemiologic features: Although epidemiologic characteristics of the adenoviruses vary by type, all are transmitted by direct contact, fecal-oral transmission, and occasionally waterborne transmission. [web.archive.org]

Other epidemiological feature was as follows: EAd were detected throughout the year. The predominant serotype was Ad40 during 1980-1985, while Ad41 were observed after 1986. EAd were detected most frequently from the children aged 0-3 years. [doi.org]

We discuss the differential diagnosis and pathophysiology of allograft viral infections and concomitant rejection. [ncbi.nlm.nih.gov]

Many adenovirus infections are subclinical or asymptomatic. 15–70% of conjunctivitis worldwide Etiology and Pathophysiology DNA virus 60 to 90 nm in size, 6 species (A through F) with >50 known serotypes Adenovirus can remain dormant in lymphoreticular [unboundmedicine.com]

Pathophysiology Adenovirus is a double-stranded DNA virus that measures 70-90 nm and that has an icosahedral capsid. [emedicine.medscape.com]

There is little information about the epidemiology, pathophysiology and the usual route of infection of Ad-36. Human adenoviruses are associated with infection of the respiratory tract, gastrointestinal tract, and conjunctiva. [doi.org]

Author information 1 Beijing Center for Disease Prevention and Control, No.16, Hepingli Middle Road, Beijing, 100013, People's Republic of China. 2 Research Centre for Preventive Medicine of Beijing, No.16, Hepingli Middle Road, Beijing, 100013, People's [ncbi.nlm.nih.gov]

For guidance to prevent adenovirus infections in healthcare settings, see Prevention & Treatment for Health Care Professionals. Treatment There is no specific treatment for people with adenovirus infection. [cdc.gov]

Additional resources The CDC—Adenoviruses Children’s Hospital of Philadelphia—Adenovirus infections APIC Infection Prevention and You—Infection Prevention Basics [apic.org]