The present review focuses on the impact of cannabinoids on apoptosis and autophagy, the two main death pathways responsible for cancer cell death.[spandidos-publications.com]
To maintain a normal size, each tissue must balance the plethora of opposite signals which arrive on its membrane surface and finely control each to prevent pathological conditions such as cancer.[spandidos-publications.com]
THC/temozolomide combined treatment enhances autophagy, whereas pharmacologic or genetic inhibition of this process prevents the effects of combined treatment, supporting that the activation of autophagy plays a crucial role in the mechanism of action[spandidos-publications.com]
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To maintain a normal size, each tissue must balance the plethora of opposite signals which arrive on its membrane surface and finely control each to prevent pathological conditions such as cancer.[spandidos-publications.com]