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Adie Syndrome


Presentation

  • […] postganglionic fibers of the parasympathetic innervation of the eye, usually by a viral or bacterial infection which causes inflammation, and affects the pupil of the eye and the autonomic nervous system. [1] Signs and symptoms [ edit ] Adie syndrome presents[en.wikipedia.org]
  • Pilocarpine test. ( 29196034 ) 2018 2 Adie Pupil as the Initial Presentation of Localized En Coup de Sabre Scleroderma. ( 28668815 ) Laxer RM...Pope E 2017 3 Areflexia in Holmes-Adie syndrome: A sign in search of its pathophysiology. ( 28939242 ) Esta[malacards.org]
Disability
  • […] administered as a treatment as well as a diagnostic measure. [1] Thoracic sympathectomy is the definitive treatment of diaphoresis, if the condition is not treatable by drug therapy. [1] Prognosis [ edit ] Adie's syndrome is not life-threatening or disabling[en.wikipedia.org]
Inflammation
  • William John Adie and Gordon Morgan Holmes who independently described the same disease in 1931. [2] It is caused by damage to the postganglionic fibers of the parasympathetic innervation of the eye, usually by a viral or bacterial infection which causes inflammation[en.wikipedia.org]
Pupillary Abnormality
  • abnormality is clearly shown to be neuronal degeneration in the ciliary ganglion. — D.[merriam-webster.com]
Photophobia
  • […] hallmark symptoms, namely at least one abnormally dilated pupil ( mydriasis ) which does not constrict in response to light, loss of deep tendon reflexes, and abnormalities of sweating. [1] Other signs may include hyperopia due to accommodative paresis, photophobia[en.wikipedia.org]
Paresis
  • […] three hallmark symptoms, namely at least one abnormally dilated pupil ( mydriasis ) which does not constrict in response to light, loss of deep tendon reflexes, and abnormalities of sweating. [1] Other signs may include hyperopia due to accommodative paresis[en.wikipedia.org]
Peripheral Neuropathy
Mydriasis
  • […] or bacterial infection which causes inflammation, and affects the pupil of the eye and the autonomic nervous system. [1] Signs and symptoms [ edit ] Adie syndrome presents with three hallmark symptoms, namely at least one abnormally dilated pupil ( mydriasis[en.wikipedia.org]
Hyporeflexia
  • 1990 36 Carotid gustatory syndrome in a patient with Holmes-Adie syndrome. ( 2341855 ) Shibasaki H...Tomi H 1990 37 A hypothetical immunemediated unifying mechanism for the Holmes-Adie syndrome. ( 3202719 ) Costa CM...do Vale DC 1988 38 On the cause of hyporeflexia[malacards.org]

Treatment

  • [ edit ] The usual treatment of a standardised Adie syndrome is to prescribe reading glasses to correct for impairment of the eye(s). [1] Pilocarpine drops may be administered as a treatment as well as a diagnostic measure. [1] Thoracic sympathectomy[en.wikipedia.org]

Prognosis

  • […] correct for impairment of the eye(s). [1] Pilocarpine drops may be administered as a treatment as well as a diagnostic measure. [1] Thoracic sympathectomy is the definitive treatment of diaphoresis, if the condition is not treatable by drug therapy. [1] Prognosis[en.wikipedia.org]

Epidemiology

  • […] treatable by drug therapy. [1] Prognosis [ edit ] Adie's syndrome is not life-threatening or disabling. [1] As such, there is no mortality rate relating to the condition; however, loss of deep tendon reflexes is permanent and may progress over time. [1] Epidemiology[en.wikipedia.org]
Sex distribution
Age distribution

Pathophysiology

  • […] loss of deep tendon reflexes, and abnormalities of sweating. [1] Other signs may include hyperopia due to accommodative paresis, photophobia and difficulty reading. [3] Some individual with Adie syndrome may also have cardiovascular abnormalities. [4] Pathophysiology[en.wikipedia.org]
  • Pilocarpine test. ( 29196034 ) 2018 2 Adie Pupil as the Initial Presentation of Localized En Coup de Sabre Scleroderma. ( 28668815 ) Laxer RM...Pope E 2017 3 Areflexia in Holmes-Adie syndrome: A sign in search of its pathophysiology. ( 28939242 ) Esta[malacards.org]

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