Symptoma

Adie Syndrome

Patients most commonly present with a classic triad of: diaphoresis absent deep tendon reflexes, e.g. ankle jerk an Adie pupil : tonically dilated and responds poorly or not at all to light Unilateral pupillary symptoms are more common than bilateral [radiopaedia.org]

It is our ambition to present a complete survey of all medical phenomena named for a person, with a biography of that person. Disclaimer: Whonamedit? does not give medical advice. [whonamedit.com]

The term Adie syndrome is used when both abnormalities of the pupil and loss of deep tendon reflexes are present. However, these findings may not develop at the same time. [rarediseases.org]

[…] postganglionic fibers of the parasympathetic innervation of the eye, usually by a viral or bacterial infection which causes inflammation, and affects the pupil of the eye and the autonomic nervous system. [1] Signs and symptoms [ edit ] Adie syndrome presents [en.wikipedia.org]

On presentation at the age of 26 she had a 2 year history of posture induced syncope together with paroxysmal throbbing headaches and epistaxis provoked by prolonged recumbency. [jnnp.bmj.com]

  • Disability

    Prognosis Holmes-Adie syndrome is not life-threatening or disabling. The loss of deep tendon reflexes is permanent. Some symptoms of the disorder may progress. [ninds.nih.gov]

    Prognosis Holmes-Adie syndrome is not life-threatening or disabling. The loss of deep tendon reflexes is permanent. Some symptoms of the disorder may progress. For most individuals, pilocarpine drops and glasses will improve vision. [brainfacts.org]

    […] administered as a treatment as well as a diagnostic measure. [1] Thoracic sympathectomy is the definitive treatment of diaphoresis, if the condition is not treatable by drug therapy. [1] Prognosis [ edit ] Adie's syndrome is not life-threatening or disabling [en.wikipedia.org]

    The disorder does not ordinarily cause severe disability. Adie syndrome usually affects the pupil of one eye, although the other eye may eventually become affected as well. [rarediseases.org]

  • Asymptomatic

    Asymptomatic autonomic and sweat dysfunction in patients with Adie’s syndrome. J Neuroophthalmol. 1998;18(2):143-47. INTERNET Lee AG. Tonic Pupil. UpToDate, Inc.June 19, 2018. Available at: Accessed April 29, 2019. McKusick VA., ed. [rarediseases.org]

  • Paroxysmal Cough

    Two years later she developed asymmetric facial sweating and paroxysmal coughing attacks, particularly while eating and during prolonged talking. [jnnp.bmj.com]

  • Pupillary Abnormality

    abnormality is clearly shown to be neuronal degeneration in the ciliary ganglion. — D. [merriam-webster.com]

  • Blurred Vision

    Glasses may be prescribed to correct blurred vision; sunglasses can help individuals with sensitivity to light. Therapy using dilute pilocarpine may improve poor depth perception and relieve glare in some patients. [rarediseases.org]

  • Suggestibility

    A normal nuclear excitability is suggested by polysynaptic activation of the soleus motor nucleus. [moh-it.pure.elsevier.com]

    In Holmes-Adie syndrome, cardiovascular 4 5 14 and tendon reflex abnormalities suggest an impairment of the afferent reflex arc. [jnnp.bmj.com]

  • Excitement

    A normal nuclear excitability is suggested by polysynaptic activation of the soleus motor nucleus. [moh-it.pure.elsevier.com]

    The pupil normally opens wider (dilates) in dim light or darkness, when focusing on far away objects, or when a person is excited. [rarediseases.org]

  • Absent Deep Tendon Reflex

    Patients most commonly present with a classic triad of: diaphoresis absent deep tendon reflexes, e.g. ankle jerk an Adie pupil : tonically dilated and responds poorly or not at all to light Unilateral pupillary symptoms are more common than bilateral [radiopaedia.org]

  • Reversible Airway Obstruction

    Investigations for cough indicated mild reversible airway obstruction. Treatment with inhaled bronchodilators and steroids (salbutamol, salmeterol, beclomethasone) produced a partial reduction in coughing. [jnnp.bmj.com]

Thoracic sympathectomy, which severs the involved sympathetic nerve, is the definitive treatment for excessive sweating. [ninds.nih.gov]

[ edit ] The usual treatment of a standardised Adie syndrome is to prescribe reading glasses to correct for impairment of the eye(s). [1] Pilocarpine drops may be administered as a treatment as well as a diagnostic measure. [1] Thoracic sympathectomy [en.wikipedia.org]

Treatment Doctors may prescribe reading glasses to compensate for impaired vision in the affected eye, and pilocarpine drops to be applied 3 times daily to constrict the dilated pupil. [brainfacts.org]

Although bronchodilator treatment improved the dyspnoea it did not prevent coughing. She had been hypertensive and noted that treatment with an angiotensin converting enzyme inhibitor exacerbated her cough and the drug was withdrawn. [jnnp.bmj.com]

Standard Therapies In most instances, treatment will not be necessary. Glasses may be prescribed to correct blurred vision; sunglasses can help individuals with sensitivity to light. [rarediseases.org]

Prognosis Holmes-Adie syndrome is not life-threatening or disabling. The loss of deep tendon reflexes is permanent. Some symptoms of the disorder may progress. [ninds.nih.gov]

This valuable tool offers detailed descriptions, facts on treatment and prognosis, and patient organization contact information for over 500 identified neurological disorders. Neurological Disorders and Stroke » [brainfacts.org]

[…] correct for impairment of the eye(s). [1] Pilocarpine drops may be administered as a treatment as well as a diagnostic measure. [1] Thoracic sympathectomy is the definitive treatment of diaphoresis, if the condition is not treatable by drug therapy. [1] Prognosis [en.wikipedia.org]

It is thought to result form damage to the ciliary ganglion and the dorsal root ganglion by viral or bacterial infections, however there are idiopathic etiologies 1,3. [radiopaedia.org]

The etiology is still unknown. Bibliography J. Ware: Observations relative to the near and distant sight of different persons. Philosophical Transactions of the Royal Society of London, 1813: 31-50. [whonamedit.com]

[…] treatable by drug therapy. [1] Prognosis [ edit ] Adie's syndrome is not life-threatening or disabling. [1] As such, there is no mortality rate relating to the condition; however, loss of deep tendon reflexes is permanent and may progress over time. [1] Epidemiology [en.wikipedia.org]

[…] loss of deep tendon reflexes, and abnormalities of sweating. [1] Other signs may include hyperopia due to accommodative paresis, photophobia and difficulty reading. [3] Some individual with Adie syndrome may also have cardiovascular abnormalities. [4] Pathophysiology [en.wikipedia.org]

Pilocarpine test. ( 29196034 ) 2018 2 Adie Pupil as the Initial Presentation of Localized En Coup de Sabre Scleroderma. ( 28668815 ) Laxer RM...Pope E 2017 3 Areflexia in Holmes-Adie syndrome: A sign in search of its pathophysiology. ( 28939242 ) Esta [malacards.org]

Much of this research focuses on finding better ways to prevent, treat, and ultimately cure disorders, such as HAS. View research on this topic. View studies being conducted about this condition. View NINDS publications on this topic. [brainfacts.org]

Much of this research focuses on finding better ways to prevent, treat, and ultimately cure disorders, such as HAS. Information from the National Library of Medicine’s MedlinePlus Autonomic Nervous System Disorders Eye Diseases [ninds.nih.gov]

Although bronchodilator treatment improved the dyspnoea it did not prevent coughing. She had been hypertensive and noted that treatment with an angiotensin converting enzyme inhibitor exacerbated her cough and the drug was withdrawn. [jnnp.bmj.com]