Presentation
Case Presentation This 22-year-old man of European descent presented with unspecific scrotal discomfort lasting for two weeks. Clinical history is uneventful. The patient is unmarried and has no children so far. [hindawi.com]
[…] at a similar age (mean: 46.5 years) Similarly presents with sheets or lobular aggregates of cells with abundant eosinophilic cytoplasm arranged with variable amounts of fibrous stroma Cells may be vacuolated and contain Reinke crystals, which are not [pathologyoutlines.com]
Presently, these tumors appear to be slow-growing neoplasm with the potential to metastasize to distant sites years after initial diagnosis. [ncbi.nlm.nih.gov]
We present a further case of GCT of the adult type in a 23 year old man. We discuss the clinical behavior and immunophenotypical characteristics of this rare tumour. [elsevier.es]
Psychiatrical
- Aggressive Behavior
behavior Gross images Contributed by Kristine M. [pathologyoutlines.com]
Workup
Laboratory workup disclosed no abnormal results. [hindawi.com]
Treatment
It’s necessary to identify prognostic factors that can reliably predict tumor behavior and to optimize methods of diagnosis and treatment .Long-term follow-up with a sufficient number of cases is recommended to define optimal treatment options since recurrence [ncbi.nlm.nih.gov]
[…] reports 22 year old man with unspecific scrotal discomfort (Case Rep Urol 2019;2019:7156154) 43 year old man with left testicular swelling (Int Braz J Urol 2015;41:1226) 65 year old man with hepatic metastasis (Indian J Pathol Microbiol 2020;63:470) Treatment [pathologyoutlines.com]
With regard to treatment, testis-sparing surgery would be the treatment of choice, as only few cases are malignant. [hindawi.com]
Prognosis
Our report highlights one more case of this very rare tumor of the testis, which is quite problematic In terms of prognosis and management, and for this reason seems to have attracted the interest of many researchers recently. [ncbi.nlm.nih.gov]
Epidemiology
[…] coding ICD-O: 8620/1 - Granulosa cell, adult type ICD-O: 8620/3 - Granulosa cell, malignant ICD-10: D40.1 - Neoplasm of uncertain behavior of unspecified testis ICD-10: C62.9 - Malignant neoplasm of testis, unspecified whether descended or undescended Epidemiology [pathologyoutlines.com]
[PubMed] [Google Scholar] Articles from The Pan African Medical Journal are provided here courtesy of African Field Epidemiology Network [ncbi.nlm.nih.gov]
Pathophysiology
ICD-10: C62.9 - Malignant neoplasm of testis, unspecified whether descended or undescended Epidemiology Rare (< 0.5% of all sex cord stromal tumors) Mean age: 40 years (range: 14 - 87 years) (Am J Surg Pathol 2014;38:1242) Sites Testicular parenchyma Pathophysiology [pathologyoutlines.com]