A PEC-CT for staging of renal cell carcinoma revealed marked splenomegaly with hypointense nodules, mild abdominal lymphadenopathy, and new lung nodules, concerning for possible metastatic carcinoma or lymphoma. [nature.com]

Patients usually present with constitutional symptoms (malaise, weight loss, fatigue), and hepatosplenomegaly is commonly found on physical exam. Lymphadenopathy is also found to a lesser extent. [en.wikipedia.org]

Epstein-Barr virus (EBV) A type of herpes virus that causes mononucleosis (a highly infectious disease that causes fever, fatigue, malaise and sore throat). [cancer.ca]

It is most commonly used in combination with chemotherapy The radiation may be administered by a machine placed outside the body, or by placing a radioactive material inside the body The side effects of radiation therapy include nausea, vomiting, fatigue [dovemed.com]

Constant antigenic stimulus such as a cytomegalovirus reactivation may be the underlying etiology of clonal T-LGL expansion and may contribute to cytopenias and fatigue seen in transplant patients [ 38 ]. 5. [intechopen.com]

The patient was admitted with a fever of 102F for 10 days, fatigue, and night sweats. Prior to the presentation, he had 3 months of intermitted low-grade fever, leukopenia and thrombocytopenia. [nature.com]

Neta Goldschmidt, Alexander Gural, Abraham Kornberg, Galia Spectre, Andrei Shopen and Ora Paltiel, Prolonged fever of unknown origin and hemophagocytosis evolving into acute lymphoblastic leukemia, American Journal of Hematology, 76, 4, (364-367), (2004 [doi.org]

Patient 2 was a 48-year-old African-American male with a history of type 2 diabetes, who initially presented with fever of unknown origin, night sweats, myalgia, and headache. [nature.com]

He presented with a fever of unknown origin, subsequently developed erythematous skin nodules, generalized lymphadenopathy, and hepatosplenomegaly, and then died of multiple organ failure. [thedoctorsdoctor.com]

fever, weight loss, jaundice, skin infiltration, lymphadenopathy, hepatosplenomegaly, and severe anemia. [orpha.net]

Clinics Patients usually present extremely ill with high fever, significant weight loss, cytopenia, jaundice and abnormal liver function. Hepatosplenomegaly is often massive accompanied by lymphadenopathy but less commonly skin lesions. [atlasgeneticsoncology.org]

T-cells or NK-cells [129,142] Severe mosquito bite allergy (SMBA) Hypersensitivity to mosquito bites, characterized by high fever after mosquito bites, ulcers, necrosis, and scarring. [omicsonline.org]

Epstein-Barr virus (EBV) A type of herpes virus that causes mononucleosis (a highly infectious disease that causes fever, fatigue, malaise and sore throat). [cancer.ca]

Yamashita Shun-ichiro Kageyama Ikuyo Endo Hiromasa Tsuda Hideki Akiyama Images in Hematology First Online: 25 May 2011 A 22-year-old woman was referred to our hospital with a 1-month history of recurrent fever, subacute onset of bilateral orbital pain, and diplopia [link.springer.com]

The diagnosis of HLH can be established by: A. a molecular diagnosis consistent with HLH or B. five of 8 criteria listed below are fulfilled; 1) Fever; 2) Splenomegaly; 3) Bicytopenias (hemoglobin 9 /L, platelets 9 /L); 4)Hypertriglyceridemia ( 265 mg [sciforschenonline.org]

Patients usually have fever, splenomegaly and cytopenias, hypertriglyceridemia and hypofibrinogenemia, and hemophagocytosis in the BM, spleen, and/or LN [ 142 ]. [omicsonline.org]

The diagnosis of HLH can be established by: A. a molecular diagnosis consistent with HLH or B. five of 8 criteria listed below are fulfilled; 1) Fever; 2) Splenomegaly; 3) Bicytopenias (hemoglobin 9 /L, platelets 9 /L); 4)Hypertriglyceridemia ( 265 mg [sciforschenonline.org]

[…] x1012/L 4.35-5.55 hemoglobin 14.1 g/dL 13.7-16.8 hematocrit 42.6 % 40.7-50.1 platelet 18 x109/L 158-348 white blood cell 3.7 x109/L 3.3-8.6 Hemogram myelocyte 5 % 0 neutrophil 58 % 40-69 lymphocyte 33 % 21-35 monocyte 1 % 4-8 atypical lymphocyte 3 % 0 erythroblast [sciforschenonline.org]

When a bone marrow biopsy is performed, the abnormal NK-cell infiltrate could be overlooked due to interstitial infiltration in a background of a hypercellular bone marrow. [nature.com]