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2.1
Aggressive Periodontitis
Juvenile Periodontitis

Presentation

Historically, the patient with juvenile periodontitis (periodontosis) presented as somewhat of an unknown entity to the orthodontist. [ncbi.nlm.nih.gov]

[…] ju·ve·nile per·i·o·don·ti·tis [MIM*170650] a degenerative periodontal disease of adolescents in which the periodontal destruction is out of proportion to the local irritating factors present on the adjacent teeth; inflammatory changes become superimposed [medical-dictionary.thefreedictionary.com]

Entire Body System

  • Pain

    This form of gingivitis is characterized by painful, bleeding gums, and death (necrosis) and erosion of gingival tissue between the teeth. [faqs.org]

    Other symptoms are rare except in patients with HIV infection or in whom abscesses develop, in which case pain and swelling are common. Diagnosis is based on inspection, periodontal probing, and x-rays. [msdmanuals.com]

    Symptoms and Signs Pain is usually absent unless an acute infection forms in one or more periodontal pockets or if HIV-associated periodontitis is present. Impaction of food in the pockets can cause pain at meals. [merckmanuals.com]

    You can save money, pain, and time by preventing future dental problems. Typically, periodontal disease does not appear until one's 30's or 40's. [drdonaldhogan.com]

  • Weight Loss

    […] reveal deep pocket Bone attachment levels relatively stable 28.  Some patients may exhibit Weight loss Mental depression General malaise Systemic condition may predispose patient to generalized juvenile periodontitis, these includes  chornic neutrophil [slideshare.net]

    Some of the systemic manifestations like weight loss, mental depression and general malaise are also seen. [identalhub.com]

Jaw & Teeth

  • Periodontitis

    […] functions in localized juvenile periodontitis. [ncbi.nlm.nih.gov]

  • Poor Oral Hygiene

    oral hygiene and inadequate nutrition.See aggressive periodontitis. aggressive periodontitis type 1 An autosomal dominant condition (OMIM:170650) characterised by severe and protracted gingival infections, leading to tooth loss. [medical-dictionary.thefreedictionary.com]

    This might be related to the low socioeconomic level and poor oral hygiene status of most of the Yemeni students. Keywords: aggressive periodontitis; risk factors; alveolar bone loss; logistic regression. [revodonto.bvsalud.org]

    The risk factors include poor oral hygiene, stress, decreased host resistance, and HIV infection [4, 11]. [hindawi.com]

    Trench mouth usually develops because of poor oral hygiene, stress, fatigue, and smoking. [encyclopedia.com]

  • Gingival Recession

    recession K06.01 Gingival recession, localized K06.010 Localized gingival recession, unspecified K06.011 Localized gingival recession, minimal K06.012 Localized gingival recession, moderate K06.013 Localized gingival recession, severe K06.02 Gingival [icd10data.com]

    ADA Class Description Type I Gingivitis No loss of attachment Bleeding on probing may be present Type II Early Periodontitis Pocket depth or attachment loss: 3-4mm Bleeding on probing may be present Localized area of gingival recession Possible grade [loveperio.com]

    Periodontal pockets or gingival recession c. Fork participation in multirooted teeth (Fig. 15-5) d. Tooth mobility and/or drifting E. localized or Generalized inflammation 1. [dent-wiki.com]

    Gingival recession. Gingivitis. Radiography. INTRODUCTION The term "aggressive periodontitis" was first introduced at the World Workshop on Periodontal Disease Classification 3. [scielo.br]

  • Premature Loss of Teeth

    loss of teeth Lumbar hyperlordosis Joint hypermobility Talipes Hyperlordosis Hamartoma Joint laxity Optic atrophy Hyperextensible skin Kyphosis Pneumonia Osteoporosis Brachycephaly Glaucoma Arthralgia Retinopathy Visual loss Bowing of the long bones [mendelian.co]

Skin

  • Eruptions

    […] alteration is seen in cases where a tooth is arrested in eruption, but where the alveolar bone continues its growth and gradually covers the tooth arrested in eruption or when the tooth erupts normally, but without concomitant growth of the alveolar [dentalhypotheses.com]

    The four first permanent molars in a 16-year-old girl with juvenile periodontitis were treated by selective grinding, tooth eruption, conventional periodontic treatment and endodontic therapy. [ncbi.nlm.nih.gov]

    Scheuthauer-Marie- Sainton syndrome Dental symptoms: high and narrow palate (with or without cleft palate) supernumerary teeth delayed eruption crowns and roots are in abnormal localisation teeth in retention are in ectopic places extremely long-lasting [fdocuments.us]

    Gingival problems that are commonly seen in children and adolescents are as follows. (1) Eruption Gingivitis. Some gingival inflammation normally accompanies eruption process [4, 9, 11]. [hindawi.com]

  • Hyperkeratosis

    Early onset periodontitis of adolescents, ♂:♀ ratio, 3:1, characterized by an early loss of alveolar bone surrounding permanent teeth; 84% have underlying endocrinopathies, 12% systemic disease–eg, DM, neutropenia, Down syndrome, Ehlers-Danlos syndrome, hyperkeratosis [medical-dictionary.thefreedictionary.com]

    Papillion LeFevre syndrome (hyperkeratosis palmoplantaris et periodontoclasia) 8. Goldscheider syndrome (epidermolysis bullosa dystrophica) Autosomal recessive inheritance 1. [fdocuments.us]

    […] nose Mild short stature Supernumerary nipple Tracheomalacia High palate Micrognathia Stippled calcification in carpal bones Tarsal stippling Elevated 8-dehydrocholesterol Patellar dislocation Punctate vertebral calcifications Tracheal calcification Hyperkeratosis [mendelian.co]

  • Palmoplantar Keratosis

    keratosis. 6 Toomes C...Thakker NS 10581027 1999 7 Reevaluation of the chromosome 4q candidate region for early onset periodontitis. 56 Hart TC...Diehl SR 8100208 1993 8 Re-interpretation of the evidence for X-linked dominant inheritance of juvenile [malacards.org]

  • Keratosis

    2010 5 Identification of a shared genetic susceptibility locus for coronary heart disease and periodontitis. 56 Schaefer AS...Schreiber S 19214202 2009 6 Loss-of-function mutations in the cathepsin C gene result in periodontal disease and palmoplantar keratosis [malacards.org]

Psychiatrical

  • Aggressive Behavior

    behavior Feeding difficulties in infancy Sleep apnea Autistic behavior Blepharophimosis Acanthosis nigricans Attention deficit hyperactivity disorder Clonus Confusion Thin vermilion border Abnormal lung morphology Abnormality of the metaphysis Abnormal [mendelian.co]

Neurologic

  • Seizure

    Seizures and intellectual disability are common, but one-third of affected individuals have normal intellect. [mendelian.co]

    Medications: Steroids, anti-seizure medicines, cancer medicines, and blood pressure medicines can all affect the gums. Some drugs decrease the flow of saliva, irritating the mouth and making it prone to infection. [drdonaldhogan.com]

    Drugs associated with this condition are phenytoin, used to treat seizures; cyclosporin, given to organ transplant patients to reduce the likelihood of organ rejection; and calcium blockers, used to treat several different heart conditions. [faqs.org]

    […] wrinkled occlusal surfaces of molars, are believed to occur during tooth development. 9 Patients with T21 have an increased incidence of gastrointestinal tract anomalies, congenital heart disease, immunodeficiency, nutritional difficulties during infancy, seizure [dentalaegis.com]

Workup

Microbiology

  • Capnocytophaga

    Capnocytophaga sp, F. nucleatum, P. intermedia, and E. corrodens were found in more than 75% of affected sites in LJP. [ncbi.nlm.nih.gov]

    Localized Aggressive Periodontitis Bacteria Two main bacteria which cause localized aggressive periodontitis are A.actinomycetemcomitans and Capnocytophaga. [identalhub.com]

Treatment

Both treatment modalities resulted in significant benefit on an individual basis. [ncbi.nlm.nih.gov]

Prognosis

This article reviews the literature on the epidemiology, aetiology, pathogenesis, clinical features, histopathological and immunological findings, differential diagnosis, treatment and prognosis of JP. [ncbi.nlm.nih.gov]

Therefore it is important to make regular appointments with your dentist to ensure that this condition is detected and treated early for a good prognosis. [intelligentdental.com]

Once the disease process has been arrested, the prognosis of each tooth is evaluated and possible rehabilitations, including orthodontic treatment and fixed prostheses, are planned. [unboundmedicine.com]

Etiology

The literature pertaining to proposed etiologic factors and treatment modalities for juvenile periodontitis is briefly reviewed. [ncbi.nlm.nih.gov]

[…] disease, recent evidence suggests that periodontosis is inflammatory, with virulent gram-negative microorganisms, selective immune deficiencies, dysfunction of polymorphonuclear leukocytes, genetic predisposition, or any combination of these as possible etiologic [nyuscholars.nyu.edu]

This review discusses the etiology and pathogenesis of JP and recommends treatment regimens, according to patient diagnosis. [scholars.uthscsa.edu]

Epidemiology

It is observed that there are contradictory reports on the epidemiology, etiology and treatment of the disease and hence the need for further studies in these areas. [ncbi.nlm.nih.gov]

Global epidemiology of periodontal diseases in children and young persons JM Albandar, EMB Tinoco Periodontology 2000 29 (1), 153-176, 2002 397 2002 Evidence for the Role of Highly Leukotoxic Actinobacillus actinomycetemcomitans in the Pathogenesis of [scholar.google.co.in]

This conclusion agrees with results drawn from previous epidemiological studies [22]. [revodonto.bvsalud.org]

Google Scholar | Crossref | Medline | ISI Waerhaug, J. (1971): Epidemiology of Periodontal Disease. In: The Prevention of Periodontal Disease, J.E. Eastoe, D.C.A. Picton, and G.A. Alexander, Eds., London: H. Kimpton, pp. 1-19. [journals.sagepub.com]

Pathophysiology

Abstract Decreased neutrophil chemotaxis has been implicated in the pathophysiology of the disease, localized juvenile periodontitis (LJP). [ncbi.nlm.nih.gov]

Internal Medicine (550) Pathology and Forensic Medicine (447) Paediatrics, Neonatology (442) Infectology (321) Physiology and Pathophysiology (318) Medical Chemistry and Biochemistry (298) Microbiology (281) Genetics (233) Surgery, Traumatology and Orthopaedics [portal.mefanet.cz]

Pathophysiology Periodontitis usually develops when gingivitis, usually with abundant plaque and calculus beneath the gingival margin, has not been adequately treated. [merckmanuals.com]

As well as Aggregatibacter actinomycetemcomitans being associated with this, the synergism of the disease also accounts for both Capnocytophaga spp and Porphyromonas gingivalis.[5] Pathophysiology[edit] Aggressive periodontitis is a multifactorial disease [en.wikipedia.org]

Prevention

Regular prophylactic scaling and polishing with frequent recalls should result in early diagnosis and in preventing the rapid progression of this condition. [ncbi.nlm.nih.gov]

There is no cure except to extract the tooth, but periodontal disease can be effectively contained to prevent further discomfort. Prevention and early detection are your best defenses against this life-long disease. [drdonaldhogan.com]

Prevention The best way to prevent periodontitis is to follow a program of good oral hygiene, one that you begin early and practice consistently throughout life. Good oral hygiene. [mayoclinic.org]

Periodontal disease is so prevalent that only possible solution to the problem is its “prevention” by maintaining the good oral hygiene. 26. [slideshare.net]

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