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Aging

Ageing


Presentation

  • In the present chapter, we present a brief overview of these studies and discuss their contributions toward our understanding of the importance of miRNAs in normal and aged stem cell function in various model systems.[ncbi.nlm.nih.gov]
  • The authors present a case study of a 70-year-old man with Down syndrome ("Mr.[ncbi.nlm.nih.gov]
  • […] and future research on aging are presented.[ncbi.nlm.nih.gov]
  • A case study of an 88-year-old breast cancer survivor with LE is presented to illustrate the effect of LE on psychosocial issues and functional abilities among aging women.[ncbi.nlm.nih.gov]
  • CONCLUSION: Elderly people in rural areas present good quality of life/health in the cognitive aspect, access to services, goods, habits, but awareness must be constant due to their weakness.[ncbi.nlm.nih.gov]
Compulsive Behavior
  • Behavioral issues and specific psychiatric diagnoses, including self-injury, anxiety, attention-deficit disorder, autistic features, depression, and obsessive-compulsive behavior, often worsen with age.[ncbi.nlm.nih.gov]
Polyneuropathy
  • Although aging is closely related with the onset of senile systemic amyloidosis (SSA) caused by wild-type transthyretin (TTR), the effect of aging on amyloid formation has remained unclear in familial amyloidotic polyneuropathy (FAP), caused by variant[ncbi.nlm.nih.gov]

Treatment

  • We also briefly reviewed available data on the treatment of arterial thrombosis in FVII deficiency.[ncbi.nlm.nih.gov]
  • DON and SID induced both early and late apoptosis in KBV20C cells in response to HAL treatment, without increasing autophagy.[ncbi.nlm.nih.gov]
  • Successful treatment requires setting realistic expectations of the benefits of replacement therapy.[ncbi.nlm.nih.gov]
  • As the number of breast cancer survivors increases due to improved detection and treatment, it becomes all the more important that health professionals focus on prevention, early detection, and treatment of LE among breast cancer survivors of all ages[ncbi.nlm.nih.gov]
  • Cancer and its treatment can lead to a myriad of adverse events and negatively impact quality of life of older cancer patients and survivors.[ncbi.nlm.nih.gov]

Prognosis

  • Doctors Give Medicare’s Proposal To Pay For Telemedicine Poor Prognosis By Phil Galewitz October 10, 2018 Federal officials are proposing that Medicare pay doctors for a 10-minute “check-in” call with beneficiaries.[khn.org]
  • In the largest tumor group in our material, prostate cancer, the blood TL 9 years before diagnosis seemed to indicate a poor prognosis.[doi.org]
  • Jun-Ting Ren, Mei-Xia Wang, Yi Su, Lu-Ying Tang and Ze-Fang Ren, Decelerated DNA methylation age predicts poor prognosis of breast cancer, BMC Cancer, 10.1186/s12885-018-4884-6, 18, 1, (2018).[doi.org]
  • Measurement of cardiac reserve in cardiogenic shock: implications for prognosis and management. Br. Heart J. 64, 121–128 (1990). 7. Thomas, D. M., Coles, G. A. & Williams, J. D. What does the renal reserve mean? Kidney Int. 45, 411–416 (1994). 8.[doi.org]

Etiology

  • Aging individuals can develop generalized, exquisitely-pruritic, eczematous eruptions of uncertain etiology that can be therapeutically-refractory and life-altering.[ncbi.nlm.nih.gov]
  • Reiter WJ, Schatzl G, Mark I et al. (2001) Dehydroepiandrosterone in the treatment of erectile dysfunction in patients with different organic etiologies. Urol Res 29: 278–281 PubMed CrossRef Google Scholar 46.[springerlink.com]
  • Etiology of hypopituitarism revealed. J. Endocr. Genet. 1, 9–19 (1999). 22. Eicher, E. M. & Beamer, W. G. Inherited ateliotic dwarfism in mice. Characteristics of the mutation, little, on chromosome 6. J. Hered. 67, 87–91 (1976). 23.[doi.org]
  • Finally we sought to determine the characteristics that might differentiate persons able to attribute their disability to specific conditions from those who cite old age as the etiology of their disability.[doi.org]
  • Finally, it provides evidence that frailty is not synonymous with either comorbidity or disability, but comorbidity is an etiologic risk factor for, and disability is an outcome of, frailty.[doi.org]

Epidemiology

  • Author information 1 Nutritional Epidemiology Research Team (EREN), Epidemiology and Statistics Research Center, U1153 National Institute of Health and Medical Research (INSERM), U1125 National Institute for Agricultural Research (INRA), National Conservatory[ncbi.nlm.nih.gov]
  • Here, we review the literature to present our current understanding of the epidemiology, causal factors, diagnosis, and treatment of anxiety in the aging woman.[ncbi.nlm.nih.gov]
  • Extensive investigation aims to elucidate the beneficial effects of ROS and NO, providing novel insights into the current medical treatment of oxidative stress-related diseases of high epidemiological impact.[ncbi.nlm.nih.gov]
  • We assessed change in depression by comparing Center for Epidemiology-Depression (CES-D) scores for 1161 men and women between 2012 and 2016, and used multiple regression to identify whether changes in chronic health conditions, grip strength and self-rated[ncbi.nlm.nih.gov]
  • Department of Psychology, Ohio State University 2 Department of Internal Medicine, Ohio State University 3 Institute for Behavioral Medicine Research, Ohio State University 4 Department of Psychology, Indiana University Southeast 5 Department of Medical Epidemiology[web.archive.org]
Sex distribution
Age distribution

Pathophysiology

  • The anesthesiologist should be knowledgeable about these age-related cardiovascular changes, the pathophysiology underlying them, and the appropriate perioperative management.[ncbi.nlm.nih.gov]
  • Tetraploidy, a condition in which a cell has four homologous sets of chromosomes, is often seen as a natural physiological condition but is also frequently seen in pathophysiological conditions such as cancer.[ncbi.nlm.nih.gov]
  • Although muscle aging has been increasingly recognized as a biomarker of aging, the pathophysiology of sarcopenia is to date only partially appreciated.[ncbi.nlm.nih.gov]
  • This review focuses on emerging topics encompassing the functional involvement of aquaporin channel proteins (AQPs) and membrane transport systems, also allowing permeation of NO and hydrogen peroxide, a major ROS, in oxidative stress physiology and pathophysiology[ncbi.nlm.nih.gov]
  • This review focuses on the current understanding of Klotho protein function, with emphasis on its potential involvement in the pathophysiologic process of CKD.[ncbi.nlm.nih.gov]

Prevention

  • Even though new trials are ongoing, the recognition of this syndrome is essential to prevent cardiovascular and cerebrovascular complications.[ncbi.nlm.nih.gov]
  • Guidelines for LE prevention and management are presented, with application to the special needs of the older breast cancer survivor. Nursing implications are discussed, with recommendations for future study.[ncbi.nlm.nih.gov]
  • These mechanisms therefore represent potential therapeutic targets in the prevention and treatment of such pathologies.[ncbi.nlm.nih.gov]
  • These mechanisms therefore represent potential therapeutic targets in the prevention and treatment of such pathologies. Copyright 2011 Cold Spring Harbor Laboratory Press; all rights reserved[doi.org]
  • Checkpoints within the cell division cycle that facilitate the accuracy and outcome of chromosome segregation are thus critical pathways for preserving chromosome integrity and preventing chromosomal instability.[ncbi.nlm.nih.gov]

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