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Agnosia

Presentation

Design/Methods: We present a 69-year-old male who presented with speech difficulty and was transferred to us for consideration of intravascular intervention for his left ICA occlusion. [n.neurology.org]

Simultanagnosia is the specific inability to recognise objects when they are presented together, however, can identify each object when presented alone. [news-medical.net]

There are several categories of agnosias but there are three most common categories presented in the literature: visual, auditory and tactile. [agnosia-ot.weebly.com]

Patients with topographical agnosia will present with getting often lost, findings directions. [statpearls.com]

Entire Body System

  • Fever

    (Derrida, Archive Fever, 1995) The idea of consignation as described by Derrida in his seminal Archive Fever may serve to shed light on another feature of the works. [ilitazoulay.com]

    Symptoms may include headache, lethargy, fever, and focal neurologic deficits. Diagnosis is by contrast-enhanced MRI or CT. [msdmanuals.com]

    Ageusia, Parosmia, Parageusia) Speech and voice speech disturbances (Dysphasia, Aphasia, Dysarthria) - symbolic dysfunctions (Dyslexia, Alexia, Agnosia, Apraxia, Acalculia, Agraphia) - voice disturbances (Dysphonia, Aphonia) General symptoms and signs Fever [bionity.com]

  • Pain

    Thought to be connected to lesions or damage in somatosensory cortex.[16] Pain agnosia Also referred to as Analgesia, this is the difficulty perceiving and processing pain; thought to underpin some forms of self injury.[17] Finger agnosia is the inability [bionity.com]

    Each participant receives a baseline pain testing session, followed by a conditioning paradigm that results in the expectation of pain relief and conditioning. [unitedbrainassociation.org]

    Patients could not acknowledge the existence of objects in the neglected field and so attempted to reach into the mirror to grasp the object. [11] Pain agnosia Also referred to as Analgesia, this is the difficulty perceiving and processing pain; thought [psychology.fandom.com]

  • Short Stature

    stature (Idiopathic) - food and fluid intake (Anorexia, Polydipsia, Polyphagia) - Cachexia - Xerostomia - Clubbing [bionity.com]

  • Unconsciousness

    It is claimed that in Capgras, there may be damage to streams of unconscious processing. This can result in a dissociation between the conscious stream identifying a person as, say, wife, and the lack of unconscious empathic feelings. [jnnp.bmj.com]

Respiratoric

  • Cheyne-Stokes Respiration

    […] cd=7&gl=au v • d • e Symptoms and signs (R00-R69, 780-789) Circulatory and respiratory systems Tachycardia - Bradycardia - Palpitation - Heart murmur - Epistaxis - Hemoptysis - Cough - abnormalities of breathing (Dyspnea, Orthopnoea, Stridor, Wheeze, Cheyne-Stokes [bionity.com]

Gastrointestinal

  • Flatulence

    Mouth breathing, Hiccup, Bradypnea, Hypoventilation) - Chest pain - Asphyxia - Pleurisy - Respiratory arrest - Sputum - Bruit/Carotid bruit - Rales Digestive system and abdomen Abdominal pain (Acute abdomen) - Nausea/Vomiting - Heartburn - Dysphagia - flatulence [bionity.com]

  • Failure to Thrive

    […] to thrive - Short stature (Idiopathic) - food and fluid intake (Anorexia, Polydipsia, Polyphagia) - Cachexia - Xerostomia - Clubbing [bionity.com]

  • Fecal Incontinence

    incontinence (Encopresis) - hepatosplenomegaly (Hepatomegaly, Splenomegaly) - Jaundice - Ascites - Fecal occult blood - Halitosis Skin and subcutaneous tissue disturbances of skin sensation (Hypoesthesia, Paresthesia, Hyperesthesia) - Rash - Cyanosis [bionity.com]

  • Abdominal Distension

    […] pain (Acute abdomen) - Nausea/Vomiting - Heartburn - Dysphagia - flatulence and related (Abdominal distension, Bloating, Burping, Tympanites) - Fecal incontinence (Encopresis) - hepatosplenomegaly (Hepatomegaly, Splenomegaly) - Jaundice - Ascites - Fecal [bionity.com]

  • Abdominal Pain

    Asphyxia - Pleurisy - Respiratory arrest - Sputum - Bruit/Carotid bruit - Rales Digestive system and abdomen Abdominal pain (Acute abdomen) - Nausea/Vomiting - Heartburn - Dysphagia - flatulence and related (Abdominal distension, Bloating, Burping, [bionity.com]

Liver, Gall & Pancreas

  • Jaundice

    […] and abdomen Abdominal pain (Acute abdomen) - Nausea/Vomiting - Heartburn - Dysphagia - flatulence and related (Abdominal distension, Bloating, Burping, Tympanites) - Fecal incontinence (Encopresis) - hepatosplenomegaly (Hepatomegaly, Splenomegaly) - Jaundice [bionity.com]

  • Hepatomegaly

    […] bruit - Rales Digestive system and abdomen Abdominal pain (Acute abdomen) - Nausea/Vomiting - Heartburn - Dysphagia - flatulence and related (Abdominal distension, Bloating, Burping, Tympanites) - Fecal incontinence (Encopresis) - hepatosplenomegaly (Hepatomegaly [bionity.com]

Psychiatrical

  • Auditory Hallucination

    Hearing gain Auditory hallucinations While hearing voices, especially if threatening or accusatory, is more likely to be due to psychiatric illness, organic disease can also result in auditory hallucinations. [jnnp.bmj.com]

Face, Head & Neck

  • Facial Scar

    Alternative Cues and Strategies Some general strategies that can be used are alternative cues, for example, teaching people with prosopagnosia to learn to identify any facial scars or hairstyles. [statpearls.com]

    Alternative Cues and Strategies Some general strategies that can be used are alternative cues, for example, teaching people with prosopagnosia learn to identify any facial scars or hairstyles. [healthjade.com]

Urogenital

  • Uremia

    Dysmetria, Dysdiadochokinesia, Hypotonia) - Tetany - Meningism - Hyperreflexia Urinary system Renal colic - Dysuria - Vesical tenesmus - Urinary incontinence - Urinary retention - Oliguria - Polyuria - Nocturia - Extravasation of urine - Extrarenal uremia [bionity.com]

  • Oliguria

    Fasciculation, Athetosis) - Gait abnormality - lack of coordination (Ataxia, Dysmetria, Dysdiadochokinesia, Hypotonia) - Tetany - Meningism - Hyperreflexia Urinary system Renal colic - Dysuria - Vesical tenesmus - Urinary incontinence - Urinary retention - Oliguria [bionity.com]

Neurologic

  • Aphasia

    Persons with Wernicke’s aphasia also have troubles understanding speech but the underlying causes are different from those in agnosia and usually they recognize speech sounds as such (see Wernicke’s aphasia). [aphasia.org]

    Various standardized tests are available to test for memory and cognition (MMSE, Montreal Cognitive assessment, ADAS-cog) and aphasia (Boston naming test, western aphasia battery). [statpearls.com]

    The following case was studied in the Aphasia Research Unit of the Boston Veterans Administration Hospital. During this time the visual disturbance was investigated in the laboratory of R. [jamanetwork.com]

  • Apraxia

    Apraxia of Gait in which co-ordination of leg actions is problematic such as kicking a ball, Constructional Apraxia in which a person can't co-ordinate the construction of objects or draw pictures or follow a design, Oculomotor Apraxia in which the ability [psychology.fandom.com]

    […] a ball, Constructional Apraxia in which a person can't co-ordinate the construction of objects or draw pictures or follow a design, Oculomotor Apraxia in which the ability to control visual tracking is impaired and Buccofacial Apraxia in which skilled [bionity.com]

    Dressing apraxia and constructional “apraxia” Confusingly, these are not apraxias as such, but are rather visuospatial deficits resulting in difficulty dressing and drawing. [jnnp.bmj.com]

    The difference with apraxia is that in the case of apraxia the objects are detected well, but knowledge about its use has disappeared. See page apraxia. [braininjury-explanation.com]

    Apraxia, agnosias, and higher visual function abnormalities. Journal of Neurology, Neurosurgery & PsychiatryGreene JD. Apraxia, agnosias, and higher visual function abnormalities. [physio-pedia.com]

  • Gerstmann Syndrome

    There are also cases of iatrogenic Gerstmann syndrome resulting from cerebral angiography.[6] Developmental Gerstmann syndrome (DGS) has been reported in children as a type of learning disorder. [eyewiki.aao.org]

    Agnosia in literature The Man who Mistook His Wife for a Hat 1 by the Anglo-American neurologist Oliver Sacks (1933-2015) 2 See also Gerstmann syndrome References Related articles: Terms used in radiology Promoted articles (advertising) [radiopaedia.org]

    It is present in lesions of the dominant parietal lobe, and is a component of Gerstmann syndrome. Simultanagnosia: Patients can recognize objects or details in their visual field, but only one at a time. [wikidoc.org]

    It is present in lesions of the dominant parietal lobe, and is a component of Gerstmann syndrome.[8] Form agnosia Patients perceive only parts of details, not the whole object.[9] Integrative agnosia This is where one has the ability to recognize elements [psychology.fandom.com]

    It is present in lesions of the dominant parietal lobe, and is a component of Gerstmann syndrome.[18] Integrative agnosia This is where one has the ability to recognize elements of something but yet be unable to integrate these elements together into [bionity.com]

  • Ataxia

    This type of visual attention problem is one of three major components (the others being optic ataxia and optic apraxia) of Bálint’s syndrome, an uncommon and incompletely understood variety of severe neuropsychological impairments involving space representation [braininjury-explanation.com]

    Balint syndrome is the triad of simultanagnosia, optic ataxia (misreaching for visual targets), and ocular apraxia (inability to control voluntary eye movements, although the eyes can move spontaneously in all directions). [merckmanuals.com]

    Hyperesthesia) - Rash - Cyanosis - Pallor - Flushing - Petechia - Desquamation - Induration - Diaphoresis Nervous and musculoskeletal systems abnormal involuntary movements (Tremor, Spasm, Fasciculation, Athetosis) - Gait abnormality - lack of coordination (Ataxia [bionity.com]

    […] of spatial perception Balint syndrome is a disorder of spatial perception comprising three aspects: simultanagnosia (the inability to comprehend a complex scene in its entirety—that is, only one component of the scene is perceived at a time), optic ataxia [jnnp.bmj.com]

  • Dysmetria

    Rash - Cyanosis - Pallor - Flushing - Petechia - Desquamation - Induration - Diaphoresis Nervous and musculoskeletal systems abnormal involuntary movements (Tremor, Spasm, Fasciculation, Athetosis) - Gait abnormality - lack of coordination (Ataxia, Dysmetria [bionity.com]

Workup

Workup Evaluation for Gerstmann syndrome begins with confirmation of the clinical findings. Finger agnosia can be tested by: Covering the patient's eyes, touching one of their fingers, and having them report which finger was touched. [eyewiki.aao.org]

Treatment

Treatment Treatment is generally symptomatic and supportive. The primary cause of the disorder should be determined in order to treat other problems that may contribute to or result in agnosia. Prognosis Agnosia can compromise quality of life. [brainfacts.org]

Complications/side effects of the treatment The possible complications or side effects of visual agnosia and the related treatments depend strongly on the type of visual agnosia and the treatments themselves. [my.clevelandclinic.org]

Read More Read Less Treatment Treatment Treatment is generally symptomatic and supportive. The primary cause of the disorder should be determined in order to treat other problems that may contribute to or result in agnosia. [ninds.nih.gov]

Agnosia Treatment Agnosia treatment involves identifying sensory processing deficits and implementing effective ways to optimize the individual’s functional independence despite them. [flintrehab.com]

Prognosis

Prognosis Prognosis Agnosia can compromise quality of life. Clinical Trials Clinical Trials [ninds.nih.gov]

Prognosis  Few patients with agnosia regain their sensory function.  Most recovery occurs within the first three months and to a variable degree may continue up to a year.  Prognosis depends on the patient's age, etiology, type, size and location of [slideshare.net]

Prognosis Agnosia can compromise quality of life. Research The NINDS supports research on disorders of the brain such as agnosia with the goal of finding ways to prevent or cure them. View research on this topic. [brainfacts.org]

Prognosis for Agnosia The prognosis for agnosia depends on several factors such as: Where the damage to your brain is located How severe the damage is How severe your symptoms are How effective the treatment of the underlying cause is Your age You can [webmd.com]

Prognosis Agnosia can compromise quality of life. Research The NINDS supports research on disorders of the brain such as agnosia with the goal of finding ways to prevent or cure them. [brainandlife.org]

Etiology

Etiology  Strokes  Tumors  Infections  Dementia  Hypoxia  Toxins such as carbon monoxide poisoning  Head injury  Developmental disorders  Other neurological conditions Kumar, A., & Wroten, M. (2019). Agnosia. 9. [slideshare.net]

Diagnosis is supplemented by neuroimaging tests such as head CT and brain MRI to look for etiology. More testing may be needed based on clinical judgment and suspected etiology. [statpearls.com]

Etiology[edit | edit source] Agnosia happens when there is brain damage along pathways that connect primary sensory processing areas. [physio-pedia.com]

[…] with some subsequent case reports reporting additional cognitive deficits.[1] Despite its recognition in the neurological literature, most knowledge has been described in case studies, and scant epidemiological data is available.[2] Localization and Etiology [eyewiki.aao.org]

Epidemiology

Epidemiology  Very rare  Less than 1 %  Visual agnosis is the most common De Renzi E. [Agnosia]. Recenti Prog Med. 1989 Dec;80(12):633-7. Coslett HB. Sensory Agnosias. In: Gottfried JA, editor. Neurobiology of Sensation and Reward. [slideshare.net]

Differentiating Agnosia from Other Diseases Epidemiology and Demographics Risk Factors Screening Natural History, Complications, and Prognosis Diagnosis Diagnostic Criteria History and Symptoms Physical Examination Laboratory Findings Imaging Findings [wikidoc.org]

[…] left-sided stroke presenting with the four cardinal signs, with some subsequent case reports reporting additional cognitive deficits.[1] Despite its recognition in the neurological literature, most knowledge has been described in case studies, and scant epidemiological [eyewiki.aao.org]

Epidemiology Pure forms of agnosia are very rare. Less than 1% of all neurological patients have agnosia. [statpearls.com]

Pathophysiology

Anosognosia is a lack of ability to perceive the realities of one's own condition.[11] [12] Pathophysiology of Agnosia[edit | edit source] To analysis something by our brain, first of all we need to have sensory stimulus (vision, hearing, taste, touch [physio-pedia.com]

Pathophysiology Causes Agnosia can result from strokes, dementia, or other neurological disorders. It may also be trauma-induced by a head injury, or hereditary. Until the 1990s, it was not believed to be genetic, but that view has changed. [wikidoc.org]

Objectives: Review the pathophysiologic basis of agnosia. Outline the expected history and physical findings for a patient with agnosia. Summarize the treatment options available for agnosia. [statpearls.com]

Prevention

Causes Some of the most probable causes of this disease are: Dementia Carbon monoxide poisoning Encephalitis Traumatic brain injuries Strokes Risks The main risk factors include: Injury of head Diabetes and obesity Smoking Ageing Prevention To prevent [medanta.org]

Because of this, it’s not usually a preventable condition. The only way to prevent or reduce your risk of developing visual agnosia is to avoid or prevent some of the conditions and problems that cause it. [my.clevelandclinic.org]

Prevention How Is Agnosia Prevented? There is no known way to prevent agnosia after the disorder-causing brain damage occurs. [unitedbrainassociation.org]

Research The NINDS supports research on disorders of the brain such as agnosia with the goal of finding ways to prevent or cure them. Information from the National Library of Medicine’s MedlinePlus Memory [brainandlife.org]

[…] disorders.[3337] People with agnosia may retain their cognitive abilities in other areas.[3336] Treatment of primary agnosia is symptomatic and supportive; when it is caused by an underlying disorder, treatment of the disorder may reduce symptoms and help prevent [rarediseases.org]

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