A 28-year-old male farmer presented to our emergency service with bilateral painful visual loss for the past 7 days that occurred suddenly after alcohol consumption. [ncbi.nlm.nih.gov]

Peak protection was present at 15.1-20.0 units/week (0.69, 0.53 to 0.89) and >4.5 units on the heaviest day (0.68, 0.57 to 0.82). [bmj.com]

• Fatigue

  Too much endorphin release can cause depression, lower sex drive, low testosterone, infertility, and extreme fatigue, among other complications. Liver My oh my, how the liver takes a hit when you get drunk. [quitalcohol.com]

  For the first six months of 2018, I tried to stick to eating a ketogenic diet (this is a good guide to keto), which worked well to increase alertness and reduce fatigue throughout the day, but was hard to keep to. [businessinsider.de]

  Fatigue but decreased ability to sleep. Decreased ability to concentrate. Mood changes (depression, anxiety, etc.) Sweating. Increased blood pressure. Rapid pulse. [drugabuse.com]

• Nausea

  Alcohol can cause flushing, nausea, increased heart rate, and slurred speech. These may be confused with or mask the symptoms of low blood sugar. [webmd.com]

  Mixing alcohol with certain medications can cause nausea, headaches, drowsiness, fainting, a loss of coordination, internal bleeding, heart problems, and difficulties in breathing. Alcohol can also make a medication less effective. [rethinkingdrinking.niaaa.nih.gov]

  If you think you might be dependent on alcohol, or if you have physical withdrawal symptoms (e.g. shaking, sweating, nausea before you have your first drink of the day) then you should seek medical advice from your GP before you stop drinking. [drinkaware.co.uk]

  Nausea. Vomiting. Dizziness/vertigo. Increased thirst. Redness of the eyes. Sensitivity to light and sound. Fatigue but decreased ability to sleep. Decreased ability to concentrate. Mood changes (depression, anxiety, etc.) Sweating. [drugabuse.com]

  The sorts of withdrawal symptoms that suggest you may need medication include: anxiety after waking sweating and tremors nausea or retching in the morning vomiting hallucinations seizures or fits Staying healthy and in control Cutting down or stopping [nhs.uk]

• Abdominal Pain

  A 43-year-old man presented with loose stools, abdominal pain and a weight loss of 15 kg. Investigations revealed a pancreatic insufficiency and an enteropathy with villous atrophy. Coeliaki was suspected. [ncbi.nlm.nih.gov]

• Insomnia

  Increased risk drinking is defined as 180-400 g/week for men and 120-280 g/week for women, with effects of less energy, depression/stress, insomnia, impotence, risk of injury, high blood pressure. [iard.org]

Reduction Aldehydes or ketones are reduced with sodium borohydride or lithium aluminium hydride (after an acidic workup). Another reduction by aluminiumisopropylates is the Meerwein-Ponndorf-Verley reduction. [en.wikipedia.org]

For women, an association was also found between having experienced injuries caused by drinking and use of self-treatment techniques and visit to a CAM practitioner. [ncbi.nlm.nih.gov]

Conclusion: In total, 20% of people diagnosed with cancer were hazardous drinkers, despite the known relationship between alcohol use and a worse prognosis of the disease and an increased likelihood of recurrence. [ncbi.nlm.nih.gov]

Males with AIP had lower total amount of spirits and lower proportion of binge drinking than those with AUD, suggesting the idiosyncratic etiology of AIP. [ncbi.nlm.nih.gov]

In recent years, increasing attention has been paid to the role of alcohol in the etiology of type 2 diabetes. A number of studies have investigated this issue, but with contradictory results. [care.diabetesjournals.org]

Second, as the etiology of AF remains incompletely understood in the majority of patients, identifying mechanisms of known risk factors might help to reveal new therapeutic targets. [jaha.ahajournals.org]

KEYWORDS: DNA methylation; PACE consortium; alcohol; cord blood; epidemiology; epigenetics; meta-analysis; pregnancy [ncbi.nlm.nih.gov]

epidemiology 32, Marten H Hofker, professor of molecular genetics 76, S Goya Wannamethee, professor of epidemiology 77, Peter H Whincup, professor of cardiovascular epidemiology 78, Richard Morris, professor of medical statistics and epidemiology 77, [bmj.com]

Abstract Metabolomics studies of disease conditions related to chronic alcohol consumption provide compelling evidence of several perturbed metabolic pathways underlying the pathophysiology of alcoholism. [ncbi.nlm.nih.gov]

Our selection of biomarkers for study was guided by links to cardiovascular pathophysiology. [bmj.com]

RESULTS: Approximately 14% of men and 12% of women reported alcohol consumption exceeding recommendations for cancer prevention. [ncbi.nlm.nih.gov]