Presentation
The divergent immunologic milieus present in ACD and psoriasis likely underly the decreased incidence of ACD in patients with psoriasis. [mdedge.com]
They are often present on the lower trunk and buttocks. These conditions can also present with plaques and nodules. Because of this variable presentation, a skin biopsy is required for confirmation. [worldallergy.org]
Allergic contact dermatitis can present on physical exam as acute or chronic. Acute ACD characteristically presents as an erythematous, eczematous, or vesicular dermatitis. [ncbi.nlm.nih.gov]
The patient presented herein exhibited allergic reactions to both luliconazole and lanoconazole. [medicaljournals.se]
The section Cases presents brief case reports that convey clear, practical lessons. Preference is given to common presentations of important rare conditions, and important unusual presentations of common problems. [cmaj.ca]
Workup
[…] positive reactions to a chemical Dimethylgloxime test: To determine whether a metallic object contains enough nickel to provoke allergic dermatitis Skin biopsy: May help to exclude other disorders, particularly tinea, psoriasis, and cutaneous lymphoma See Workup [emedicine.medscape.com]
Treatment
Treatment Team Penn's world renowned Dermatologists provide expert treatment for Allergic Contact Dermatitis. Browse our list of physicians. [pennmedicine.org]
Patients should not simply receive treatment and sent out the door with a prescription. It is crucial to tailor the treatment to the patient, and the body part affected. [ncbi.nlm.nih.gov]
One of the current primary treatments for severe allergic contact dermatitis is the use of corticosteroids. Long-term use of corticosteroids can result in skin atrophy, spider veins, loss of skin color or corticosteroid acne. [sciencedaily.com]
After responding to initial treatment, the patient was discharged with ibuprofen and a tapering dose of oral prednisone from 60 mg 5 times daily, to 40 mg 5 times daily, to 20 mg 5 times daily over 15 days. [mdedge.com]
Treatment may vary from leaving the skin absolutely untreated, or washing it with copious amounts of water and avoiding further exposure to the offending substance, to corticosteroid therapy. [news-medical.net]
Prognosis
Prognosis for allergic contact dermatitis is usually worse compared to irritant contact dermatitis unless the allergen is identified and avoided (1). A common cause of this type of dermatitis is nickel. Reference: (1) Rashid RS, Shim TN. [gpnotebook.com]
Prognosis Most cases of contact dermatitis are easily treated and will resolve with time if we avoid the substance that is causing the allergic or irritant reaction. [healthengine.com.au]
Contact allergy to topical medicaments is more common in persons older than 70 years. [15] Prognosis The prognosis depends on how well the affected individual can avoid the offending allergen. [16] Individuals with allergic contact dermatitis may have [emedicine.medscape.com]
Prognosis depends on patient education and compliance in avoiding allergens and appropriate skin care. See smartphone apps to check your skin. [dermnetnz.org]
The prognosis is very good but scarring can occur. An example would be exposure to wet cement causing a “cement burn”. [wsiat.on.ca]
Etiology
[…] and Classifications The etiology of hand dermatitis is often multifactorial. [the-dermatologist.com]
Involvement in Mycosis Fungoides. 38 Barata MC...Silva MRR 30839339 2019 36 The epidemic of methylisothiazolinone contact allergy in Europe: follow-up on changing exposures. 38 Uter W...European Environmental Contact Dermatitis Research Group 31419348 2019 37 Etiological [malacards.org]
[…] accounts for 20% of contact dermatoses, and allergens differ greatly based upon geography, personal habits and hobbies, and often, the types of preservatives that are legally permissible, such as quaternium-15 in the United States but not Europe. [3] Etiology [ncbi.nlm.nih.gov]
Etiology Approximately 25 chemicals appear to be responsible for as many as one half of all cases of allergic contact dermatitis. These include nickel, preservatives, dyes, and fragrances. [emedicine.medscape.com]
DIFFERENTIAL DIAGNOSES CD may be suspected based on the clinical appearance and distribution of the lesions, lack of associated systemic symptoms and the absence of other plausible etiologies. [worldallergy.org]
Epidemiology
Allergic contact dermatitis: epidemiology, molecular mechanisms, in vitro methods and regulatory aspects. Current knowledge assembled at an international workshop at BfR, Germany. Cell Mol Life Sci. 2012;69(5):763-81. (3) Bourke J et al. [gpnotebook.com]
In 2007, Thyssen and colleagues 4 performed a retrospective study that reviewed the main findings from previously published epidemiological studies on contact allergy in unselected populations including all age groups and most publishing countries (mainly [accessmedicine.mhmedical.com]
GRANTS/AWARDS 2 nd Round Grant Applications - Deadline: April 15, 2020 by 11:59pm CST Clinical Research Award This award is presented to young investigators studying occupational dermatology and/or epidemiology of contact dermatitis. [contactderm.org]
The possibly antagonistic relationship between these immunologic processes is further supported by epidemiologic studies demonstrating a decreased incidence of ACD in patients with psoriasis. 6,7 Our patient demonstrated a typical ACD reaction in response [mdedge.com]
The epidemiology of contact allergy in the general population – prevalence and main findings. Contact Dermatitis 2007: 57: 287–299. [ PubMed ] 3. Pazzaglia M, Pasquale L, Colombina V, Tosti A. Contact dermatitis from nickel in mobile phone. [escholarship.org]
Pathophysiology
Pathophysiology The pathophysiology of allergic contact dermatitis begins with the contact of the allergen to the skin. [ncbi.nlm.nih.gov]
This article reviews ACD-aiming to connect recent investigational data with the current clinical understanding of disease pathophysiology, diagnostic techniques, and management strategies. [wjgnet.com]
Allergic conjunctivitis: update on pathophysiology and prospects for future treatment. J Allergy Clin Immunol. 2005;115(1):118–22. 10. Torkildsen G, Shedden A. [bmcophthalmol.biomedcentral.com]
Basic mechanisms and pathophysiology of allergic contact dermatitis. In: UpToDate, Fowler J (Ed). (Accessed on September 27, 2016.) Yiannias,J. Clinical features and diagnosis of allergic contact dermatitis. In: UpToDate, Fowler J (Ed). [dermnetnz.org]
During the initial consultation, physicians must educate patients about the pathophysiology of ACD: its delayed presentation, its relationship with the immune system (sensitization to a chemical and then elicitation of dermatitis with re-exposure) and [the-dermatologist.com]
Prevention
Prevention You can take the following steps to help prevent contact dermatitis: Avoid irritants and allergens. Try to identify and avoid the cause of your rash. [mayoclinic.org]
Logistics and expense prevents including many allergens in a baseline panel. [wjgnet.com]
Latex Allergy: A Prevention Guide. Questions and Answers about identifying and preventing latex allergy. [cdc.gov]
Can contact dermatitis be prevented? The only way to prevent contact dermatitis is to avoid contact with the irritant or allergen that causes it. [hopkinsmedicine.org]
Prevent hand-foot-and-mouth disease It’s contagious, but you can reduce your child’s risk of catching it. Find out what helps. Scabies? Treat everyone! If your child develops scabies, everyone in your household will need treatment. [aad.org]