Dosage and using this medicine Activase (alteplase) is for intravenous administration only. It is important that you consult your doctor or pharmacist on how to use the medication correctly and follow all instructions carefully. [alteplase.com]

The solution may be used for intravenous administration within 8 hours following reconstitution when stored between 2 -30 C (36 -86 F). [globalrph.com]

MIX GENTLY LET IT SETTLE (SEVERAL MINUTES) INSPECT SOLUTION The solution may be used for intravenous administration within 8 hours following reconstitution when stored between 2-30 C (36-86 F). [activase.com]

(1,5 million units within 60 minutes) together with hypodermic or intravenous administration of heparin (7,3%). [en.medicalmeds.eu]

Because of noncompliance with postoperative thromboprophylaxis, there was high suspicion for PE. [ncbi.nlm.nih.gov]

The per-protocol population was defined as all randomly assigned patients who received alteplase or placebo and who were not excluded because of major protocol violations, which included, most notably, noncompliance with the current European Summary of [nejm.org]

CONCLUSION: A 63-year-old man with renal amyloidosis and SVC syndrome secondary to HITT was successfully treated with argatroban and CDT with alteplase. [ncbi.nlm.nih.gov]

Finnerty J, Heaney A, Leonard C, McKnight K, Turkington J, Wroath B, Dewan B, Cotton S, Gardiner M, Saunders T, Vincent B, Sims D, Guest P, Jones E, McCormack J, Nicholl D, Savanhu J, Tongue R, Willmot M, Eveson D, Dawson S, Dickens M, Fotherby M, Hunt [ncbi.nlm.nih.gov]

Diseases such as chronic myelogenous leukemia, chronic lymphocytic leukemia, non-Hodgkin lymphoma, and essential thrombocythemia were included, but the complication rate and outcomes of this subset were not reported. 173 A single case report of a 24-year-old [stroke.ahajournals.org]

CASE SUMMARY: A 62-year-old white woman admitted with respiratory distress and hypotension developed a right-sided multi-loculated pleural effusion. Thoracentesis and chest tube drainage were not successful in resolving the effusion. [ncbi.nlm.nih.gov]

PHYSICAL THERAPY IMPLICATIONS Examination and Evaluation Assess for signs of bleeding and hemorrhage (bleeding gums; nosebleed; unusual bruising; coughing up blood; black, tarry stools; hematuria; fall in hematocrit or blood pressure). [fadavispt.mhmedical.com]

Call your doctor or get emergency medical help if you have signs of bleeding, such as: sudden headache, feeling very weak or dizzy; bleeding gums, nosebleeds; easy bruising; bleeding from a wound, incision, catheter, or needle injection; bloody or tarry [everydayhealth.com]

Call your doctor or get emergency medical help if you have signs of bleeding, such as: sudden headache, feeling very weak or dizzy; bleeding gums, nosebleeds ; easy bruising; bleeding from a wound, incision, catheter, or needle injection; bloody or tarry [drugs.com]

Bleeding in various sites, including nosebleeds, bleeding gums, blood in the urine, bleeding in the throat or gut, coughing or vomiting blood. A blood transfusion may sometimes be needed. Heart attack. [netdoctor.co.uk]

A percutaneous mechanical thrombectomy and CDT with alteplase were attempted, but the procedure was aborted due to epistaxis. The epistaxis resolved the next day, and the patient was restarted on argatroban. [ncbi.nlm.nih.gov]

[…] requires an admission to 7 West Indications Unable to use Central Venous Catheter Unable to aspirate blood/Heplock prior to Haemodialysis Adverse Reactions Bleeding - from recent puncture or IV sites - this requires careful nursing attention Echymosis, epistaxis [rch.org.au]

EENT: epistaxis, gingival bleeding. Resp: bronchospasm, hemoptysis. CV: reperfusion arrhythmias, hypotension, RECURRENT ISCHEMIA/THROMBOEMBOLISM. GI: GI BLEEDING, nausea, RETROPERITONEAL BLEEDING, vomiting. GU: GU TRACT BLEEDING. [fadavispt.mhmedical.com]