Presentation
We present a case of a 48-year-old man with histologically confirmed malignant transformation of a benign ameloblastic fibroma 10 years after initial presentation of a localized facial mass. [ncbi.nlm.nih.gov]
A substantial number of conditions affecting the jaws may present tumor radiographic appearance. [revestomatologia.sld.cu]
Entire Body System
- Accelerated Growth
A 28-year-old asthmatic Nigerian female presented at the Oral Surgery Clinic of the University College Hospital with a 4-year history of a gradually enlarging right maxillary swelling which accelerated in growth following two pregnancies. [jomfp.in]
Eyes
- Eye Pain
pain, andproptosis for which he wore protective safety glasses. [dokument.tips]
Psychiatrical
- Suggestibility
ConclusionThe results suggest that FASN and COX-2 overexpression may have a role in the pathogenesis of AM and AC¸ while in AFS, only FASN seems to be involved. [medworm.com]
The lesion grew rapidly in the time from hospital admission until operation, suggesting progression from low to high malignancy. The correlation between the benign epithelial component and malignancy is discussed. [ncbi.nlm.nih.gov]
Although most cases arise de novo, the documentation of a prior or pre-existing precursor lesion from ameloblastic fibroma suggests otherwise.1,2 A study by Kobayashi et al. suggested that up to one-third of AFS arise from AF while a review of literature [pjohns.pso-hns.org]
They were found to be in mild-labeling indices suggesting of less aggressive tumor. Hence, we considered a conservative approach for the treatment. Treatment options for AF swings between conservative excision and aggressive resection. [njms.in]
Face, Head & Neck
- Facial Mass
We present a case of a 48-year-old man with histologically confirmed malignant transformation of a benign ameloblastic fibroma 10 years after initial presentation of a localized facial mass. [ncbi.nlm.nih.gov]
mass with accompanying paresthesia Diagnosis Diagnosis dependent on clinical, radiologic and pathologic correlation Radiology description Appears as an expansive, multilocular radiolucent lesion Often shows cortical perforation Radiology images Images [pathologyoutlines.com]
The usual clinical presentation consists of a patient who complains of a painful but occasionally painless facial mass with accompanying paresthesia or dysesthesia. The duration of symptoms varies widely from a few weeks up to 2 years [7]. [hindawi.com]
Neurologic
- Dysesthesia
The usual clinical presentation consists of a patient who complains of a painful but occasionally painless facial mass with accompanying paresthesia or dysesthesia. The duration of symptoms varies widely from a few weeks up to 2 years [7]. [hindawi.com]
The usual clinical presentation consists of a patient who complains of a painful but occasionally painless facial mass with accompanying paresthesia or dysesthesia. The duration of symptoms varies widely from a few weeks up to 2 years [ 7 ]. [ncbi.nlm.nih.gov]
Treatment
Surgical resection remains the standard treatment, as no clear or consistent pattern exists for the use of adjuvant therapy in the primary treatment of AFS. [ochsnerjournal.org]
This potential transformation alone does not justify radical treatment of all these benign lesions. [ncbi.nlm.nih.gov]
Prognosis
Its behaviour is relatively benign, with absence of metastatic disease, and the prognosis is reported to be good. It is a paradoxical neoplasm with "sarcomatous" morphological and immunohistochemical patterns but with a favourable clinical course. [ncbi.nlm.nih.gov]
Natural History, Complications, and Prognosis Prognosis Prognosis of fibrosarcoma depends on the tumor grade. [wikidoc.org]
[…] this highly lauded three-volume reference provides an interdisciplinary approach to the diagnosis, treatment, and management of head and neck diseases, including the incidence, etiology, clinical presentation, pathology, differential diagnosis, and prognosis [books.google.com]
Some authors have proposed that AFS should be considered as low grade fibrosarcoma [7] in view of its more favourable prognosis in comparison to fibrosarcomas of the orofacial region. [article.sapub.org]
Etiology
Suresh Vyloppilli: Malankara Orthodox Syrian Church Hospital and MedicalCollege Biomedical Journal of Scientific & Technical Research, 2017, vol. 1, issue 1, 222-223 Abstract: Ameloblastic Fibrosarcoma is an extremely rare odontogenic tumor with unclear etiology [econpapers.repec.org]
Updated, reorganized, and revised throughout, this highly lauded three-volume reference provides an interdisciplinary approach to the diagnosis, treatment, and management of head and neck diseases, including the incidence, etiology, clinical presentation [books.google.com]
[…] malignant stroma Epidemiology Rare, < 100 case reports in English literature More common in males (1.5 - 1.6:1) Mean age: 3rd decade Sites More common in mandible (80%); favors posterior mandible Can have maxillary involvement; may extend into sinus Etiology [pathologyoutlines.com]
Epidemiology
[…] counterpart to ameloblastic fibroma Terminology Ameloblastic fibrosarcoma Ameloblastic fibrodentinosarcoma: used when dentin is present within the malignant stroma Ameloblastic fibroodontosarcoma: used when enamel is present within the malignant stroma Epidemiology [pathologyoutlines.com]
Epidemiology and Demographics Fibrosarcoma accounts for about 5% of all primary bone sarcomas. Incidence Fibrosarcoma is a rare disease. Worldwide, the incidence of fibrosarcoma is 0.05 per 100,000 persons. [wikidoc.org]
452 Loya-Solis A, Gonzalez-Colunga KJ, Barboza- Quintana O (2015) Ameloblastic fibrosarcoma of the mandible a case report and brief review of the literature, Case Rep Pathol, Vol.2015 ; pp.245026 Fletcher CDM Fletcher CDM (2002) Soft tissue tumours Epidemiology [journal.kaomp.org]
It is a tumor of mesenchymal origin and the epidemiologic factors are still unknown, but many authors report radiation therapy history as a possible one (3). [scielo.isciii.es]
Pathophysiology
[…] of its compartment Stage II Stage IIA: High grade lesion that is confined to its anatomic compartment Stage IIB: High grade lesion that have extended outside of its compartment Stage III lesions are any grade or anatomic site that have metastasized Pathophysiology [wikidoc.org]
Pathophysiology Fibrosarcoma is a tumor of mesenchymal cell origin that is composed of malignant fibroblasts in a collagen background. There are two main types: primary and secondary. [emedicine.medscape.com]
Prevention
Knowledge of the malignant potential in the mesenchymal spindle cells of ameloblastic fibroma will assist in determining the management of these benign tumours, and may prevent malignant transformation to ameloblastic fibrosarcoma. [ncbi.nlm.nih.gov]
Expanded section on bisphosphonate-related osteonecrosis of the jaws helps you effectively manage patients taking bisphosphonates to prevent bone loss, including information on oral complications, risk factors, and benefits. [books.google.com]
We hope this treatment will be sufficient to prevent recurrence and give our patient the best chance of long-term survival. [ochsnerjournal.org]
On the one hand, it would be good to take the measures recommended by the doctors to prevent further recurrences of the disease. [deti.zp.ua]