Brown pigment is present in middle layers of enamel. Disease Ontology : 12 An amelogenesis imperfecta that has material basis in homozygous mutation in the SLC24A4 gene on chromosome 14q32. [malacards.org]

Brown pigment is present in middle layers of enamel. {ECO:0000269 PubMed:23375655, ECO:0000269 PubMed:24621671}. Note=The disease is caused by mutations affecting the gene represented in this entry. [genecards.org]

Females that have an altered gene present on one of their X chromosomes are carriers for that disorder. Carrier females usually do not display symptoms because females have two X chromosomes and only one carries the altered gene. [rarediseases.org]

Through our online ordering and statement reporting system, Nucleus, the customer has an access to details of the analysis, including patient specific sequencing metrics, a gene level coverage plot and a list of regions with inadequate coverage if present [blueprintgenetics.com]

More Symptoms of Amelogenesis imperfecta, hypomaturation type IIA5 » • • • Back to: « Amelogenesis imperfecta Diagnosis See also related information on diagnosis: Diagnosis of Amelogenesis imperfecta Treatments See also the following treatment articles [familydiagnosis.com]

At the moment, there is no standard treatment for amelogenesis imperfecta. Treatment depends on the type and severity of the condition. [healthline.com]

Consult your personal physician or other professional health care provider when seeking individualized treatment regarding your medical diagnosis or condition. [varsome.com]

Relevant External Links for SLC24A4 Genetic Association Database (GAD) SLC24A4 Human Genome Epidemiology (HuGE) Navigator SLC24A4 Atlas of Genetics and Cytogenetics in Oncology and Haematology: SLC24A4 No data available for Genatlas for SLC24A4 Gene Genetic [genecards.org]

A mutation in any one of these genes can prevent it from making the correct protein, leading to enamel that is thin or soft. [healthline.com]