Presentation
It provides a comprehensive review of the epidemiology, diagnosis, and management of opportunistic infections and presents strategies for infection prevention and control. [books.google.com]
Presentation on theme: "Free-Living Amoebae Dr. Amira Taman."— Presentation transcript: 1 Free-Living Amoebae Dr. [slideplayer.com]
This presentation is often more aggressive in cases due to Balamuthia mandrillaris when compared to cases due to Acanthamoeba spp 4. [radiopaedia.org]
Patients can present in a comatose state. As the amoeba causes extensive destruction of brain tissue, dramatic neurological presentations occur - eg, fitting, loss of body control, seizures, and hallucinations. [patient.info]
Entire Body System
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Fatigue
Symptoms of Amebiasis Diarrhea, possibly containing blood or mucus Rectal pain during bowel movements (tenesmus) Intestinal gas (excessive flatulence) Severe abdominal cramping and tenderness Excessive gas Loss of weight High fever Fatigue Nausea and [healthcommunities.com]
Weight loss and fatigue can also occur. If the amoebic dysentery goes untreated, it can progress to extraintestinal amoebiasis, although this is rare. [study.com]
But it may cause milder chronic symptoms of: frequent loose stools abdominal pain cramps fatigue intermittent constipation diarrhoea with abdominal swelling flatulence. Amoebae are parasites that are found in contaminated food or drink. [netdoctor.co.uk]
These could include: Diarrhea Dysentery Fatigue Fever Excessive gas Rectal pain, occurring with bowel movement Vomiting It is possible for the protist to enter the circulatory system and continue to invade other organs, such as the liver, lungs, and sometimes [dovemed.com]
Some early symptoms might include a combination of the following:• Severe headache• Stiff neck, or neck pain with neck movement• Sensitivity to light• Nausea and vomiting• Unusual fatigue• Fever• Difficulty walking or talking• Sudden one-sided weakness [slideshare.net]
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Cat Scratch
Features up-to-date information on HIV/AIDS, with an emphasis on Africa; malaria; tropical gastroenterological problems; dengue and dengue hemorrhagic fever; tuberculosis; Sexually Transmitted Diseases; SARS; avian flu; bartonellosis, cat-scratch disease [books.google.com]
Gastrointestinal
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Nausea
Symptoms include headaches, stiff neck, nausea and vomiting, tiredness, confusion, lack of attention to people and surroundings, loss of balance and bodily control, seizures, and hallucinations. [ehagroup.com]
Some early symptoms might include a combination of the following:• Severe headache• Stiff neck, or neck pain with neck movement• Sensitivity to light• Nausea and vomiting• Unusual fatigue• Fever• Difficulty walking or talking• Sudden one-sided weakness [slideshare.net]
Symptoms of a liver abscess include: fever and weakness abdominal swelling and pain cough nausea (feeling sick) jaundice loss of appetite weight loss The symptoms of amoebic dysentery usually last a few days to several weeks. [your.md]
Symptoms include fever, sweats, chills, weakness, nausea, vomiting, weight loss, and pain or discomfort in the upper right part of the abdomen over the liver. Rarely, amebas spread to other organs (including the lungs or brain). [msdmanuals.com]
Symptoms of Amebiasis Diarrhea, possibly containing blood or mucus Rectal pain during bowel movements (tenesmus) Intestinal gas (excessive flatulence) Severe abdominal cramping and tenderness Excessive gas Loss of weight High fever Fatigue Nausea and [healthcommunities.com]
Neurologic
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Headache
Symptoms include headaches, stiff neck, nausea and vomiting, tiredness, confusion, lack of attention to people and surroundings, loss of balance and bodily control, seizures, and hallucinations. [ehagroup.com]
Some early symptoms might include a combination of the following:• Severe headache• Stiff neck, or neck pain with neck movement• Sensitivity to light• Nausea and vomiting• Unusual fatigue• Fever• Difficulty walking or talking• Sudden one-sided weakness [slideshare.net]
[…] flagellates and cysts never found in tissue or CSF 12 1ry amoebic meningoencephalitis Children and young adult Previously healthy History of bathing, swimming, diving or playing in warm stagnant, fresh water Few days to 2 weeks prior to onset of symptoms Headache [slideplayer.com]
N. fowleri was cultured from the water. [ 12 ] Presentation : similar to bacterial/viral meningitis: Symptoms - headache, photophobia, nausea and vomiting. [patient.info]
Patients with GAE have been described with symptoms that include: headache, low fever, seizures, hemiparesis, and coma leading to eventual death 2. [radiopaedia.org]
Workup
In addition to standard blood tests, other laboratory studies employed for diagnosis include microscopy, culture, serologic testing, and polymerase chain reaction (PCR) assay (see Workup). [emedicine.medscape.com]
Treatment
Features: Every chapter has been extensively revised and updated, nearly half with new author teams NEW chapter on acute encephalitis NEW clinical information on treatment of tuberculosis, non-tubercular mycobacterial infections, brain abscess, and Lyme [books.google.de]
Describes the latest therapies, such as recently approved drugs and new treatment options, so you can incorporate them into to your practice. [books.google.com]
It is not indicated for the treatment of asymptomatic cyst passage. [checkorphan.org]
The lack of established success in treatment means that there is no single, proven, evidence-based treatment that carries a high probability of cure, although in recent times miltefosine shows promise. [patient.info]
It's important to avoid drinking alcohol during treatment. Even if you have to treat yourself, it's important to see a doctor to ensure that the treatment has been truly effective. [netdoctor.co.uk]
Prognosis
Prognosis The prognosis depends on the location of the infection and the patient's general health prior to infection. [medical-dictionary.thefreedictionary.com]
(Outcomes/Resolutions) The prognosis of an individual with Amebiasisis generally good with proper treatment A subsequent check of the individual’s infection status after treatment may ensure complete eradication of the amoeba Additional and Relevant Useful [dovemed.com]
Prognosis : Mortality of GAE is high, reaching almost 100% when skin lesions and CNS disease both occur together. [patient.info]
Prognosis The prognosis for Acanthamoeba is worse than for many other types of infectious keratitis and prevention is therefore very important. However, especially if caught early, satisfactory outcomes can certainly be achieved. [eyewiki.aao.org]
[…] literature, but can include the following brain lesions 6 : multiple parenchymal lesions pseudotumoural lesions meningeal exudates hemorrhagic infarcts (more common in Balamuthia mandrillaris ) necrosis (more common in Balamuthia mandrillaris ) Treatment and prognosis [radiopaedia.org]
Etiology
Etiology and Incidence Two of the eight known species of Acanthamoeba, A. castellanii and A polyphaga, are responsible for most infections. [eyewiki.aao.org]
Background Amebiasis is caused by Entamoeba histolytica (see the image below), a protozoan that is found worldwide (see Etiology). [1, 2, 3, 4] The highest prevalence of amebiasis is in developing countries where barriers between human feces and food [emedicine.medscape.com]
Meanwhile, N. fowleri, was reported to be the etiological agent for 12 cases of PAM in Thailand [ 22, 23 ]. [journals.plos.org]
Epidemiology
It provides a comprehensive review of the epidemiology, diagnosis, and management of opportunistic infections and presents strategies for infection prevention and control. [books.google.com]
Epidemiology : Most reports are from the USA and India. Very rare - estimated at 1 in 2.6 million exposed individuals. [patient.info]
Epidemiology of Acanthamoeba spp. and Naegleria fowleri Both of these organisms are distributed globally in the environment, however, they rarely cause disease. [ehagroup.com]
• Epidemiology - the incidence of AK is 3 per 100,000 and around 85% of cases occur in people who wear contact lenses• Presentation - secondary bacterial infection occurs commonly, making it difficult to diagnose. – Symptoms - watering of eyes, eye [slideshare.net]
Epidemiology of amebiasis in a region of high incidence of amebic liver abscess in central Vietnam. Am J Trop Med Hyg. 2002 May. 66(5):578-83. [Medline]. Bowley DM, Loveland J, Omar T, Pitcher GJ. [emedicine.medscape.com]
Pathophysiology
General Pathology and Pathophysiology Acanthamoeba is ubiquitous. [eyewiki.aao.org]
Pathophysiology E histolytica is a pseudopod-forming, nonflagellated protozoal parasite that causes proteolysis and tissue lysis (hence the species name) and can induce host-cell apoptosis (see the image below). [emedicine.medscape.com]
Prevention
It provides a comprehensive review of the epidemiology, diagnosis, and management of opportunistic infections and presents strategies for infection prevention and control. [books.google.com]
Preventing food and water from being contaminated with human feces is key to preventing amebiasis. Improving sanitation systems in areas where the infection is common can help. [msdmanuals.com]
Primary prevention Since treatment is toxic, lengthy, and not necessarily effective, prevention is essential. Contact lens wearers should be taught how to clean their contact lenses properly. [eyewiki.aao.org]
Infection and Prevention The new hosts are usually infected by drinking water contaminated with the feces of people shedding Entamoeba histolytica cysts. [study.com]
Practice safer sex, including using condoms for anal contact and dental dams for oral contact to help prevent infection. Diagnosis Patient history and physical examination are needed. [healthcommunities.com]