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Ampulla of Vater Obstruction Syndrome


Presentation

  • An exquisite art program that focuses on clarity of presentation with an emphasis on anatomy, pathology, patient presentation, and clinical context.[books.google.com]
  • Ampullary neuroendocrine tumor presenting with biliary obstruction and gastric outlet obstruction.[jpalliativecare.com]
  • Due to the early presentation of ampullary tumors and relative distance from the mesenteric vessels, vascular involvement is uncommon.[abdominalkey.com]
  • These tumors tend to present earlier than their pancreatic and distal bile duct brethren.[readbyqxmd.com]
  • Abstract A 61-year-old woman presented with features of acute cholangitis and distal common bile duct obstruction. Histopathology from ampulla of Vater biopsy demonstrated extensive local amyloid deposition.[acgcasereports.gi.org]
Surgical Procedure
  • A duodenoduodenostomy is another surgical procedure sometimes used to create a connection or opening between the two portions of the divided duodenum.[rarediseases.org]
Amyloidosis
  • […] is common, the liver is never the sole organ affected. 15 Amyloidosis still carries a significant mortality with a median 1-year survival of 50% in untreated AL amyloidosis. 16 Over half of patients with evidence of hepatic amyloidosis will have proteinuric[acgcasereports.gi.org]
Biliary Colic
  • Biliary colic occurs when the ducts become partially obstructed. More complete obstruction causes duct dilation, jaundice, and, eventually, cholangitis (a bacterial infection).[msdmanuals.com]
  • CHEMOTHERAPY Triclabendazole Single dose of 10 mg/kg Better absorption with fatty meal Adverse effect – biliary colic; antispasmodic to be administered concurrently Other drugs Bithionol dehydroemetine nitazoxanide 20.[slideshare.net]
  • colic 胆石仙痛 biliary liver cirrhosis胆汁性肝硬変 biliary tract 胆道 bilirubin ビリルビン board-like abdomen 板状硬 bougienageブジー拡張術 bowel movement便通 bowel preparation腸管洗浄 brushing cytology擦過細胞診 c cancer of stomach (stomach cancer)胃癌 carbohydrate antigen (CA) 19-9CA 19[tokyo-med.ac.jp]

Treatment

  • Significant updates on bariatric surgery, Barrett's esophagus, endoscopic ultrasound, endosonography, treatment of liver disease, and much more keep you current on the latest advances.[books.google.de]
  • Collection of Medical Illustrations (the CIBA "Green Books") has been expanded and revised to capture current perspectives in hepatology, pancreatology, and gastroenterology - from normal anatomy and physiology through pathophysiology, diagnostics and treatment[books.google.com]
  • Treatment When symptoms are severe, standard treatment is to perform an endoscopic procedure called ERCP (endoscopic retrograde cholangiopancreatography). ERCP is a procedure for the examination or treatment of the bile duct and pancreatic duct.[iffgd.org]
  • Surgery is the primary treatment for ampullary cancer. Advanced cases may be treated with stents and palliative treatment. Treatment of ampullary cancer is based on the size and stage of the tumor.[medindia.net]

Prognosis

  • PMID: 1729790 Prognosis Tarnasky PR Expert Rev Gastroenterol Hepatol 2016 Dec;10(12):1359-1372. Epub 2016 Nov 2 doi: 10.1080/17474124.2016.1251308.[ncbi.nlm.nih.gov]
  • If left untreated, it is fatal Prognosis will depend on the presence of associated cardiac, tracheo-esophageal, anal, renal, or skeletal abnormalities (VATER) Double Bubble Sign.[learningradiology.com]
  • Primary surgical treatment with curative intent should be performed although this type of carcinoma associates with dismal prognosis.[pancreas.imedpub.com]
  • […] and have a better prognosis.[abdominalkey.com]
  • Prognosis factors in carcinoma of the head of the pancreas. Dig Surg. 2000;17:29-35. Paulino AC, Latona C. Unresectable adenocarcinoma of the pancreas: patterns of failure and treatment results. Cancer Invest. 2000;18:309-13.[path.upmc.edu]

Etiology

  • Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology.[icd10coded.com]
  • Etiology Expert Rev Gastroenterol Hepatol 2016 Dec;10(12):1359-1372. Epub 2016 Nov 2 doi: 10.1080/17474124.2016.1251308.[ncbi.nlm.nih.gov]
  • Biliary cysts: etiology, diagnosis and management. World J Gastroenterol 2012;18:4801–4810. 25. Lee HK, Park SJ, Yi BH, Lee AL, Moon JH, Chang YW. Imaging features of adult choledochal cysts: a pictorial review. Korean J Radiol 2009;10:71–80. 26.[kjronline.org]
  • Definition / general By definition, centered in ampulla of Vater, arises from ampullary intestinal mucosa If advanced, cannot distinguish tumor origin between ampulla, distal common bile duct or pancreas Etiology May arise from villous adenoma or villoglandular[pathologyoutlines.com]
  • Etiology is probably infection, most likely with cytomegalovirus, Cryptosporidium sp, or microsporidia. Liver function tests Ultrasonography Common duct stones should be suspected in patients with jaundice and biliary colic.[msdmanuals.com]

Epidemiology

  • Methods Statistics Trigonometry Medical & Nursing Anatomy Anesthesiology Audiology Bacteriology Biochemistry Bioethics Biomedical Science Cardiology Cardiovascular Childbirth Chiropractic Dentistry Dermatology Diagnostic Imaging Drugs Endocrinology Epidemiology[brainscape.com]
  • FASCIOLIASIS Etiology: Zoonosis caused by trematode Fasciola hepatica Fasciola gigantica Epidemiology F. hepatica – temperate zones F. gigantica – tropical zones Now has become global in distribution 4.[slideshare.net]
Sex distribution
Age distribution

Pathophysiology

  • This book in The Netter Collection of Medical Illustrations (the CIBA "Green Books") has been expanded and revised to capture current perspectives in hepatology, pancreatology, and gastroenterology - from normal anatomy and physiology through pathophysiology[books.google.com]

Prevention

  • Because of its location, this cancer can cause obstruction of the common bile duct and prevent bile from flowing into the intestine and out of the body.[medicinenet.com]
  • […] through the ampulla: the sphincter of the pancreatic duct, the sphincter of the bile duct, and the sphincter of Oddi. [ citation needed ] The sphincter of Oddi controls the introduction of bile and pancreatic secretions into the duodenum, as well as preventing[en.wikipedia.org]
  • Bile duct disease – the commonest indication for ERCP is the investigation and treatment of jaundice due to bile duct obstruction, preventing bile draining into the gut.[netdoctor.co.uk]
  • These obstructions in the digestive tract of infants prevent proper absorption of food.[rarediseases.org]
  • While a full covering over a stenosis is ideal to utilize maximum efficacy, an unnecessary coverage should be avoided to prevent the complications.[readbyqxmd.com]

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