Presentation
In 2011, scientists found that a defect in the C9ORF72 gene is not only present in a significant subset of individuals with ALS but also in some people with a type of frontotemporal dementia (FTD) that results from atrophy to the brain’s temporal and [ninds.nih.gov]
Entire Body System
- Weight Loss
Weight loss, dysphagia and supplement intake in patients with amyotrophic lateral sclerosis (ALS): impact on quality of life and therapeutic options. BMC Neurology 2013;13:84-93. [ Links ] 29. [scielo.isciii.es]
Gastrointestinal
- Dysphagia
Weight loss, dysphagia and supplement intake in patients with amyotrophic lateral sclerosis (ALS): impact on quality of life and therapeutic options. BMC Neurology 2013;13:84-93. [ Links ] 29. [scielo.isciii.es]
Individuals may develop problems with moving, swallowing (called dysphagia), speaking or forming words (dysarthria), and breathing (dyspnea). [ninds.nih.gov]
- Choking
People may begin using suction devices to remove excess fluids or saliva and prevent choking. [ninds.nih.gov]
Musculoskeletal
- Muscle Spasticity
A neurologic examination at regular intervals can assess whether symptoms such as muscle weakness, muscle wasting, and spasticity are progressively getting worse. [ninds.nih.gov]
- Muscle Weakness
A neurologic examination at regular intervals can assess whether symptoms such as muscle weakness, muscle wasting, and spasticity are progressively getting worse. [ninds.nih.gov]
Neurologic
- Dysarthria
Individuals may develop problems with moving, swallowing (called dysphagia), speaking or forming words (dysarthria), and breathing (dyspnea). [ninds.nih.gov]
Treatment
There is no treatment to reverse damage to motor neurons or cure ALS. However, treatments can help control symptoms, prevent unnecessary complications, and make living with the disease easier. [ninds.nih.gov]
Symptomatic treatments for amyotrophic lateral sclerosis/motor neuron disease. Cochrane Database Syst Rev 2017;1:CD011776. DOI: 10.1002/14651858.CD011776.pub2 [ Links ] 28. Körner S, Hendricks M, Kollewe K, Zapf A, Dengler R, Silani V, et al. [scielo.isciii.es]
Epidemiology
Epidemiology and pathogenesis of amyotrophic lateral sclerosis. En: Uptodate. Eichler AF (ed.). 2018. Acceso enero 2018. Disponible en: http://www.uptodate.com/ [ Links ] 3. Ministerio de Sanidad, Servicios Sociales e Igualdad. [scielo.isciii.es]
Prevention
People may begin using suction devices to remove excess fluids or saliva and prevent choking. [ninds.nih.gov]