Most patients with anal fissure will complain of pain on defecation. This pain is described as burning or tearing, worse during defecation and lasts for hours after bowel movement. This pain worsens with each bowel movement and makes the patients unwilling to have a bowel movement leading to worsening constipation and even more pain. Patients also complain of fresh blood on stool or on the toilet paper but it is not mixed with stool. There is no significant blood loss in anal fissure even though a few drops of blood may be seen dripping into the toilet water [4].

Most anal fissures occur in the posterior or anterior midline. Any fissure occurring outside the midline should raise suspicions of underlying medical conditions like infection, Crohn disease or cancer.

• Constipation

  All Videos for Anal Fissure Childhood Constipation & Cow’s Milk The elimination of all dairy products was found to cure constipation in up to 100% of kids tested, leading to a resolution of rectal inflammation and complications such as anal fissures. [nutritionfacts.org]

  Pain and constipation were assessed prior to treatment and at 6 weeks after therapy using visual analogue scale (VAS) and Wexner constipation score. Adverse effects as headache and postural hypotension were also queried. [ncbi.nlm.nih.gov]

  […] scented toilet paper Promptly treat all occurrences of constipation and diarrhea Avoid irritating the rectum © Copyright 1995-2011 The Cleveland Clinic Foundation. [web.archive.org]

  Common causes in adults include constipation and trauma to the anus (such as a difficult childbirth). Around half of cases heal by themselves with proper self-care and avoidance of constipation. [betterhealth.vic.gov.au]

• Fecal Incontinence

  PATIENTS: Women treated for chronic anal fissure with high anal resting pressure and no symptoms of fecal incontinence were selected. [ncbi.nlm.nih.gov]

• Rectal Bleeding

  Patients suffer from anal pain lasting up to several hours after defecation and rectal bleeding.3 Most acute anal fissures heal spontaneously, but a proportion progress into chronic fissures with symptoms beyond 8-12 weeks. [clinicaltrials.gov]

  One patient underwent surgery at follow-up due to recurrence of symptoms, and rubber band ligation was applied to another patient who had internal hemorrhoidal rectal bleeding at the end of 10 days. [ncbi.nlm.nih.gov]

• Rectal Pain

  Anal fissures are an extremely common problem and in fact represent the most common cause of rectal pain and bleeding in the adult population. Usually anal fissures will heal very rapidly within 24-48 hours given normal bowel movements. [colonandrectalsurgeonskc.com]

  Rectal Pain Relief There are four common causes of rectal pain. Anal fissures, hemorrhoids, anal spasms, and Levator ani syndrome. Pain from conditions that cause rectal pain can be treated by condition. [emedicinehealth.com]

  Using an anoscope may also help your doctor find other causes of anal or rectal pain such as hemorrhoids. In some cases of rectal pain, you may need an endoscopy for better evaluation of your symptoms. [healthline.com]

• Anal or Rectal Pain

  This medical instrument is a thin tube that allows doctors to inspect the anal canal. Using an anoscope may also help your doctor find other causes of anal or rectal pain such as hemorrhoids. [healthline.com]

  For patient education resources, see the Digestive Disorders Center, as well as Anal Abscess, Rectal Pain, and Rectal Bleeding. [emedicine.medscape.com]

• Hypertension

  Do not use RECTIV if you: Are taking a medicine for erectile dysfunction (male impotence), such as Viagra ® (sildenafil), Cialis ® (tadalafil), or Levitra ® (vardenafil), or for pulmonary hypertension. [rectiv.com]

  Constipation is affecting almost 13 % of the population, much higher than what diabetes and hypertension are affecting our population. [lybrate.com]

  Idiopathic hypertensive anal canal: a place of internal sphincterotomy. J Gastrointest Surg. 2009 Sep. 13 (9):1607-13. [Medline]. Grucela A, Salinas H, Khaitov S, Steinhagen RM, Gorfine SR, Chessin DB. [emedicine.medscape.com]

• Ulcer

  ANAL FISSURE, ANAL ULCER, Fissure, Anal, Anal fissure, unspecified, Anal ulcer unspecified, Anal Fissure, anal ulcer (diagnosis), anal fissure (diagnosis), anal ulcer, anal fissure, anal ulcer (___ cm), Fissure anal, Ulcer anal, Ulceration of anus, [fpnotebook.com]

  Abstract Chronic anal fissure is a linear ulcer in the anal canal that has not cicatrized for more than 8-12 weeks of treatment. Most anal fissures are idiopathic and are located in the posterior midline. [ncbi.nlm.nih.gov]

  – Triad of indurated ulcer edges, a distal skin tag (sentinel pile) and a proximal hypertrophic anal papilla. [slideshare.net]

  Anal fissure is an ulcer-like, longitudinal tear in the anal canal, most commonly located in the dorsal or ventral midline, and distal to the dentate line. Anal fissures constitute a common medical problem that affects sexes equally. [clinicaltrials.gov]

• Fear

  Sometimes the most difficult thing about a problem is overcoming the fear of facing it. [columbiasurgery.org]

  Many patients are fearful of having a bowel movement and may try to avoid defecation secondary to the pain. What is the treatment for anal fissures? The majority of anal fissures do not require surgery. [dccevv.com]

  By JEN GUNTER Photo Credit iStock Doctors Treating a Patient With a Nightmarish Condition She had lost all of her skin and I feared I had helped make her last weeks an unrelenting horror show, until our chance reunion. By ALESSANDRA COLAIANNI, M.D. [nytimes.com]

  Fear of pain may put some patients off going to the toilet, increasing their risk of constipation. If the person delays using the bathroom, this can make the pain and the tear worse, because the stools will be harder and larger. [medicalnewstoday.com]

  Complications Complications from surgery for anal fissure include infection, bleeding, fistula development, and—the most feared—incontinence. [web.archive.org]

Usually, a diagnosis of anal fissure can be made with the combination of a gentle perineal examination and the history. Digital rectal exams are painful and are better deferred. If the fissure cannot be seen on examination, anoscopy should be done. Anoscopy is a painful procedure and application of topical lidocaine helps to alleviate the pain and improve tolerance. Patients with chronic fissures tend to tolerate pain better and proctosigmoidoscopy should be done [5].

• Polyps

  […] and fibrous polyp relieves symptoms and offers good healing for fissure – Has been described as initial modes of treatment. [slideshare.net]

  […] diagnosis Colonoscopy within 3 years after initial polyp removal; if normal, as per average risk recommendations above Patients with one large (≥1 cm) adenomatous polyp or multiple adenomatous polyps of any size Colonoscopy At time of initial polyp diagnosis [aafp.org]

  It should be noted that a prolonged stasis of fecal matter may give rise to the formation of polyps in the rectum. In some cases polyps will have to be removed surgically. [pravdareport.com]

Treatment of anal fissure incorporates both medical and surgical components. Medical treatment involves the use of stool softeners and agents to make the stool more malleable and decrease the trauma associated with defecation. Sitz bath, in which the patient is advised to soak in a hot bath, will help to soothe the muscle spasm and decrease the pain associated with it and also help improve blood supply to the area and promote healing.

Infiltration of the internal sphincter with botulinum toxin creates a reversible paralysis which leads to better perfusion and a faster healing rate. Nitroglycerin ointment is also effective treatment although its side effect, headache, limits its use. Nifedipine ointment has a similar mechanism of action as nitroglycerin without the undesired side effect [6]. When conservative measures have failed, surgery is performed and the procedure of choice is lateral internal anal sphincterotomy.

It is not a life threatening condition so the mortality from anal fissure is essentially non-remarkable. It however has crippling morbidity. Less than 10% of patients will have a recurrence of anal fissure after sphincterotomy. This recurrence is may be attributed to an underlying disease or from an improperly/incompletely performed sphincterotomy. This necessitates frequent visits to the surgeon and possibly more surgical procedures.

The precise etiology of this condition is unknown although it is believed to be caused by trauma. The commonest source of trauma is from passage of particularly hard stools. The etiology is also associated with constipation, straining, inflammation, childbirth, anal cancer, and infections like syphilis, HIV, herpes and tuberculosis. Other factors that contribute to the formation of fissures are previous anorectal surgeries like hemorrhoidectomy or fistulotomy [2].

Anal fissure occurs more in younger children and middle aged adults with an incidence of as much as 1 in 350. It is occurs with identical frequency in both sexes. There is no documented racial predilection.

Most cases of minor anal tears heal on their own within 4 to 6 weeks, but if there is an underlying abnormality in the internal sphincter, these injuries progress and result in acute and chronic fissures. In studies done on anal physiology, at least one abnormality has been found in the anal sphincter of patients with anal fissure. The most common abnormalities are the ones that lead to increased anal canal and sphincter resting pressure like hypertonicity and hypertrophy of the internal anal sphincter.

Another mechanism is due to poor perfusion of the posterior anal commissure. This rather mild blood supply is further compromised in patients with hypertrophied internal anal sphincters which makes the posterior midline of the anal canal ischemic. The pain experienced during each bowel movement due to stretching of the mucosa and grazing of this area with stool causes spasm which causes more pain and further compromises the blood supply to the area and leads to poor healing [3].

It is not entirely possible to prevent anal fissure but the risk can be reduced by taking steps to avoid constipation. Such measures include eating a high fiber diet, maintaining proper hydration preferably with water and regular exercise. Also, don’t ignore the urge to have a bowel movement, the longer the wait, the harder and dryer the stool gets [7].

Anal fissure is a fairly common condition and most of the cases resolve without any medical intervention. It is common in young infants and it often causes pain and blood in stool. If it doesn’t resolve, professional help should be sought [1].

Definition

Anal fissure is a tear in the delicate lining of the anal canal. It results from forceful stretching of the mucus lining of the anal canal and happens mostly during defecation.

Cause

It is mostly caused by passage of hard stool which results from constipation. Other causes could be from chronic illnesses, inflammation of the anal region and previous surgical procedures on the anal region.

Symptoms

The commonest symptom is pain on passing stools. Pain is often burning and tearing in nature and last for hours after passing stools. There could also be blood seen on the stool or on the toilet paper used for cleaning. There could also be drops of blood could be seen in the toilet water, this blood loss is not enough to cause any significant drop in blood levels [8].

Diagnosis

Diagnosis is usually by careful examination of the anal canal, and this is usually enough to reach a definite conclusion. If the fissure is not seen, some imaging studies could be performed. These procedures are painful and are usually performed under anesthesia [9].

Treatment

Treatment involves the use of medications to soften the stools. Also sitz baths help to relax the spasm and reduce pain. Some topical solutions are also used to reduce pain, improve blood supply and improve healing. Surgery may be done if conservative measures fail to produce desired effects [10].

1. Grucela A, Salinas H, Khaitov S, et al. Prospective analysis of clinician accuracy in the diagnosis of benign anal pathology: comparison across specialties and years of experience. Dis Colon Rectum. Jan 2010;53(1):47-52.
2. Schiano di Visconte M, Munegato G. Glyceryl trinitrate ointment (0.25%) and anal cryothermal dilators in the treatment of chronic anal fissures. J Gastrointest Surg. Jul 2009;13(7):1283-91.
3. Samim M, Twigt B, Stoker L, Pronk A. Topical diltiazem cream versus botulinum toxin a for the treatment of chronic anal fissure: a double-blind randomized clinical trial. Ann Surg. Jan 2012;255(1):18-22.
4. Abd Elhady HM, Othman IH, Hablus MA, et al. Long-term prospective randomised clinical and manometric comparison between surgical and chemical sphincterotomy for treatment of chronic anal fissure. S Afr J Surg. Nov 2009;47(4):112-4.
5. Rather SA, Dar TI, Malik AA, et al. Subcutaneous internal lateral sphincterotomy (SILS) versus nitroglycerine ointment in anal fissure: A prospective study. Int J Surg. Feb 13 2010
6. American Society of Colon and Rectal Surgeons, Standards Task Force. Practice Parameters for Ambulatory Anorectal Surgery. In: Diseases of the Colon & Rectum. Vol 34. Philadelphia, Pa: Lippincott Williams and Wilkins; 1991:. 285.
7. Gibbons CP, Read NW. Anal hypertonia in fissures: cause or effect?. Br J Surg. Jun 1986;73(6):443-5.
8. Klosterhalfen B, Vogel P, Rixen H, Mittermayer C. Topography of the inferior rectal artery: a possible cause of chronic, primary anal fissure. Dis Colon Rectum. Jan 1989;32(1):43-52. 
9. Richard CS, Gregoire R, Plewes EA, et al. Internal sphincterotomy is superior to topical nitroglycerin in the treatment of chronic anal fissure: results of a randomized, controlled trial by the Canadian Colorectal Surgical Trials Group. Dis Colon Rectum. Aug 2000;43(8):1048-57; discussion 1057-8. 
10. Schouten WR, Briel JW, Auwerda JJ, De Graaf EJ. Ischaemic nature of anal fissure. Br J Surg. Jan 1996;83(1):63-5.