[…] patients were symptomatic at presentation. [saudijgastro.com]

Clinical History 76 year old female presents with painful defecation, rectal bleeding and iron deficient anaemia. Lower GI endoscopy revealed a rectal mass. [eurorad.org]

The patient did not present important complications in the immediate postoperative period. [scielo.br]

Since smooth muscle is present throughout the body, leiomyosarcoma can occur anywhere in the body. [mdanderson.org]

• Pain

  Clinical History 76 year old female presents with painful defecation, rectal bleeding and iron deficient anaemia. Lower GI endoscopy revealed a rectal mass. [eurorad.org]

  Case 2 An 88-year-old male presented to the emergency room with complaints of abdominal pain, fever, and chills. [hindawi.com]

  In addition to low abdominal pain, the patient had experienced low back pain, urinary frequency, and tenesmus for approximately 1 year. She had undergone myomectomy 2 years previously in China. The patient’s menses had ceased at the age of 50. [ovarianresearch.biomedcentral.com]

  The common symptoms of rectal leiomyosarcoma are changes in bowel habits, rectal and anal pain, a pressure sensation, and anal bleeding (6). In our case, the patient was admitted with complaints of anal bleeding and lower abdominal pain. [tcr.amegroups.com]

• Pathologist

  The pathologic diagnosis can be difficult, and sometimes review of the biopsy by an expert pathologist is needed. A complete staging is needed before formulating a treatment plan. [mdanderson.org]

  Microscopic diagnosis and differentiation of malignant from benign features require a pathologist with special interest and expertise with these lesions. [link.springer.com]

  In our department, MDT meetings for colorectal malignant tumors have been established, and the committee includes surgical oncologists, medical oncologists, radiation oncologists, pathologists and radiologists. [tcr.amegroups.com]

• Surgical Procedure

  Wide local excision was performed in 10 patients, whereas a more radical surgical procedure, including abdominoperineal resection (n=8), pelvic exenteration (n=2), and low anterior resection (n=1), were performed in 11 patients. [link.springer.com]

  Five months after the surgical procedure, in a radiological follow-up, abdominal ultrasound and abdominal-pelvic CT without contrast, due to deterioration of the renal function, revealed pleural effusion, ascites, hepatomegaly as well as multiple well-defined [ncbi.nlm.nih.gov]

• Fever

  Case 2 An 88-year-old male presented to the emergency room with complaints of abdominal pain, fever, and chills. [hindawi.com]

  Case report A 61-year-old male patient, smoker, with a history of long-standing melena of several years, associated with fever, weight loss, and pelvic and lumbar pain of 3 months of evolution. [ncbi.nlm.nih.gov]

• Asymptomatic

  Often these tumors are initially asymptomatic due to their submucosal origin. Clinical diagnosi depends on awareness of these lesions, digital rectal examination, endoscopic examination, and tissue biopsy. [link.springer.com]

  The presenting symptoms are rectal pain, constipation, rectal fullness, and diarrhea, although some patients may be asymptomatic [3]. [ovarianresearch.biomedcentral.com]

The preoperative metastatic workup did not report abnormalities. Axial image of abdominal CT with contrast that shows a solid heterogeneous mass in the rectosigmoid junction (white arrow). [ncbi.nlm.nih.gov]

Treatment by Cancer Type NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) are posted with the latest update date and version number. The NCCN Guidelines are copyrighted by the NCCN. All rights reserved. [nccn.org]

Due to its rarity, the standard treatment has not been defined. The purpose of this study was to present the follow-up of a patient with leiomyosarcoma of medium rectum submitted to exclusive operative treatment. [scielo.br]

What are the treatment options for leiomyosarcoma? Surgery is the mainstay of treatment for leiomyosarcoma, but radiation therapy and chemotherapy are often used in conjunction with surgery. [mdanderson.org]

Treatment The patient was offered surgical management via abdominoperineal resection, but he declined. [ncbi.nlm.nih.gov]

Surgery is the treatment of choice that offers the best oncologic results in these cases. [revistagastroenterologiamexico.org]

What is the prognosis for someone diagnosed with leiomyosarcoma? The prognosis for leiomyosarcoma varies greatly depending on the stage of disease. Size and metastatic spread are key factors in leiomyosarcoma. [mdanderson.org]

Conclusion In conclusion, leiomyosarcoma of the colon is a rare and aggressive neoplasm with poor prognosis. It can mimic other tumors and GI diseases but should be distinguished as a separate entity as the prognosis and treatment vary. [hindawi.com]

Leiomyosarcoma has a poor prognosis, with a 5-year survival rate of 30% in the minority of patients without associated risk factors. [scielo.org.co]

Prognosis is also poor; tumor size, histological grade, mitotic index, and local staging are the most known prognosis factors. [jmedicalcasereports.biomedcentral.com]

Using a histological grading system that included tumour differentiation, mitotic count and amount of necrosis, high grade sarcomas were associated with a worse prognosis. [pubmed.ncbi.nlm.nih.gov]

[…] has currently been shown that the period can be shorter, with the appearance of radiation-induced tumors from 6 months to 20 years after treatment completion.3 It is known that the development of these tumors is the result of the interaction of many etiologic [revistagastroenterologiamexico.org]

Definition / general Smooth muscle tumor with atypia plus either mitotic activity, tumor cell necrosis or size > 10 cm 10% of adult soft tissue sarcomas Variants are described separately above Epidemiology Skin / subcutis: see cutaneous variants above [pathologyoutlines.com]

A population- based epidemiologic and prognostic study of 48 patients, including cellular DNA content. [ncbi.nlm.nih.gov]

Wide local resection was not superior to a more radical surgical approach in preventing tumor recurrence or improving survival. [link.springer.com]

The high risk of CRC is attributed to three main factors: the carcinogenic effect of chronic mucosal inflammation, genetic predisposition, and environmental factors. 1,2 To prevent morbidity and mortality associated with CRC in patients with IBD, endoscopic [scielo.org.co]