Edit concept Question Editor Create issue ticket

Anaplasma


Presentation

  • This article presents two case reports of Anaplasma platys detection in two women from Venezuela.[ncbi.nlm.nih.gov]
  • In the present study, we obtained purified recombinant A. platys P44 and Omp-1X proteins, and using them as antigens in immunoblotting examined seroreactivity in dogs.[ncbi.nlm.nih.gov]
  • Anaplasma infections are usually challenging to diagnose, clinically presenting with nonspecific symptoms that vary greatly depending on the agent involved, the affected host, and other factors such as immune status and coinfections.[ncbi.nlm.nih.gov]
  • I. pacificus – West Coast Rocky Mountains at 4,000-10,000 feet of altitude E. chaffeensis, E. ewingii – southeastern, south central, and mid-Atlantic states EML – Wisconsin and Minnesota Clinical presentation Influenza-like illness Rash – uncommon (can[arupconsult.com]
  • Case definition Anaplasmosis Information for Health Professionals Information for health professionals including clinical presentation.[health.state.mn.us]
Italian
  • The presence of A. phagocytophilum DNA in the Apennine chamois represents the first report for this Italian endemic subspecies. Copyright 2016 The Authors. Published by Elsevier GmbH.. All rights reserved.[ncbi.nlm.nih.gov]
Cape Verde
  • The former three pathogens cause important canine tick-borne diseases that are transmitted or potentially transmitted by Rhipicephalus sanguineus s.l., the only hard tick identified in Cape Verde.[ncbi.nlm.nih.gov]
Erythema
  • Detection of Borrelia burgdorferi –specific DNA in urine specimens from patients with erythema migrans before and after antibiotic therapy . J. Clin. Microbiol. 34 : 1359 – 1363 . . 1979 .[academic.oup.com]
Neglect
  • These guidelines have been developed as a direct outcome of the COST action TD1303 EURNEGVEC ("European Network of Neglected Vectors and Vector-Borne Diseases").[ncbi.nlm.nih.gov]
  • These guidelines have been developed as a direct outcome of the COST action TD1303 EURNEGVEC ( European Network of Neglected Vectors and Vector-Borne Diseases ).[digital.csic.es]
Lethargy
  • They are mostly non-specific, consisting of fever, anorexia and lethargy. Joint pain may occur.[ncbi.nlm.nih.gov]

Workup

Rickettsia Rickettsii
  • Antibodies against Anaplasma spp. and SFG Rickettsia were determined by indirect immunofluorescence using commercially available slides coated with Anaplasma phagocytophilum and Rickettsia rickettsii antigens.[ncbi.nlm.nih.gov]
  • Infection in humans: Some rickettsial species ( A phagocytophilum, Ehrlichia chaffeensis, Ehrlichia ewingii, Rickettsia conorii, Rickettsia rickettsii, Rickettsia felis, Rickettsia typhi and Candidatus Neoehrlichia mikurensis) are of zoonotic concern.[ncbi.nlm.nih.gov]
  • Disease can be severe, particularly when patients are infected with Rickettsia rickettsii (Rocky Mountain Spotted Fever); patients may develop central nervous system involvement, shock, and multiorgan failure.[oxfordmedicine.com]
  • Nonpathogenic rickettsiae in Dermacentor andersoni: a limiting factor for the distribution of Rickettsia rickettsii, pp. 585–594 . In [eds.], Rickettsiae and rickettsial diseases . Academic , New York . . 1982 .[academic.oup.com]
Toxoplasma Gondii
  • gondii, Babesia microti MN, Babesia microti ATCC 53899, Borellia burgdorferi ATCC 51990, Ehrlichia risticii ATCC VR-986, and Anaplasma marginale .[mayomedicallaboratories.com]
Bartonella Quintana
  • quintana, Ricketssia typhi, Ricketssia rickettsii, Toxoplasma gondii, Babesia microti MN, Babesia microti ATCC 53899, Borellia burgdorferi ATCC 51990, Ehrlichia risticii ATCC VR-986, and Anaplasma marginale .[mayomedicallaboratories.com]
Bartonella Henselae
  • henselas, Bartonella quintana, Ricketssia typhi, Ricketssia rickettsii, Toxoplasma gondii, Babesia microti MN, Babesia microti ATCC 53899, Borellia burgdorferi ATCC 51990, Ehrlichia risticii ATCC VR-986, and Anaplasma marginale .[mayomedicallaboratories.com]
Staphylococcus Aureus
  • aureus, Staphylococcus epidermidis, Streptococcus pyogenes, Escherichia coli, Pseudomonas aeruginosa, Bartonella henselas, Bartonella quintana, Ricketssia typhi, Ricketssia rickettsii, Toxoplasma gondii, Babesia microti MN, Babesia microti ATCC 53899[mayomedicallaboratories.com]

Treatment

  • Intra-platelet inclusion bodies resembling A. platys were observed in buffy coat smears and A. platys DNA was amplified and sequenced from whole blood; however, treatment with doxycycline did not alleviate their symptoms.[ncbi.nlm.nih.gov]
  • Diagnostic tests are imperfect, and prompt empiric treatment should be initiated if disease is suspected. Doxycycline is the treatment of choice, and coinfection with other vector-borne pathogens may need to be considered.[oxfordmedicine.com]
  • Tetracyclines are currently available drugs for clearance of infection and treatment in humans and animals. Worldwide vaccine is not yet available.[ncbi.nlm.nih.gov]
  • The incidence of tick-borne diseases is rising worldwide, challenging our approach toward diagnosis, treatment and control options.[ncbi.nlm.nih.gov]
  • […] rely on their own discretion and judgment in medical diagnosis and treatment.[redbook.solutions.aap.org]

Etiology

  • These have long been known as etiological agents of veterinary diseases that affect domestic and wild animals worldwide. A zoonotic role has been recognized for A. phagocytophilum, but other species can also be pathogenic for humans.[ncbi.nlm.nih.gov]
  • The former is the etiological agent of canine cyclic thrombocytopenia, while the latter is that of canine granulocytic anaplasmosis.[ncbi.nlm.nih.gov]
  • The etiologic agent of anaplasmosis is Anaplasma phagocytophilum, a rickettsial bacterium. The disease was first recognized during 1993 in several patients from Minnesota and western Wisconsin.[health.state.mn.us]
  • Identification of a granulocytic Ehrlichia species as the etiologic agent of human disease . J. Clin. Microbiol. 32 : 589 – 595 . . 2003 .[academic.oup.com]

Epidemiology

  • Because hosts are usually seronegative in the initial phase of infection and serological cross-reactions with several Anaplasma species are observed after seroconversion, direct tests are the best approach for both case definition and epidemiological[ncbi.nlm.nih.gov]
  • As is the case for many tick-borne diseases, the epidemiological cycle is associated to the environmental conditions, including the presence of wild vertebrate reservoir hosts, vectors, climate and vegetation.[ncbi.nlm.nih.gov]
  • BACKGROUND: To better understand the epidemiology of tick-borne disease in Mongolia, a comprehensive seroprevalence study was conducted investigating exposure to Anaplasma spp. and spotted fever group (SFG) Rickettsia spp. in nomadic herders and their[ncbi.nlm.nih.gov]
  • Our results provide important data to increase the understanding of the epidemiology of anaplasmosis and ehrlichiosis of red deer and sika deer and will assist with the implementation of measures to control anaplasmosis and ehrlichiosis transmission to[ncbi.nlm.nih.gov]
  • KEYWORDS: Anaplasma species; Epidemiology; control; distribution[ncbi.nlm.nih.gov]
Sex distribution
Age distribution

Pathophysiology

  • Useful For Suggests clinical disorders or settings where the test may be helpful Evaluating patients suspected of acute anaplasmosis or ehrlichiosis Clinical Information Discusses physiology, pathophysiology, and general clinical aspects, as they relate[mayomedicallaboratories.com]

Prevention

  • The frequency of tick-borne pathogens detected in dogs in Maio Island, including R. monacensis, highlights the need to improve diagnosis and control in order to prevent the risk of transmission of these pathogens among dogs and humans living in or travelling[ncbi.nlm.nih.gov]
  • Prevention Typically, cases of anaplasmosis increase in late summer and fall as insect vectors increase. Therefore, control of vectors is key to preventing anaplasmosis.[thecattlesite.com]
  • Prevention Restricting exposure to potentially infected blacklegged ticks is the key to preventing Anaplasmosis.[gov.mb.ca]
  • Anaplasmosis and other tickborne diseases can be prevented. “Part of the issue is greater awareness and more testing by people who fall ill.[precisionvaccinations.com]

Ask Question

5000 Characters left Format the text using: # Heading, **bold**, _italic_. HTML code is not allowed.
By publishing this question you agree to the TOS and Privacy policy.
• Use a precise title for your question.
• Ask a specific question and provide age, sex, symptoms, type and duration of treatment.
• Respect your own and other people's privacy, never post full names or contact information.
• Inappropriate questions will be deleted.
• In urgent cases contact a physician, visit a hospital or call an emergency service!