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Anasarca

Generalized Edema


Presentation

  • Intravascular lymphoma (IVL) is a rare extra nodal subtype (usually of B-cell origin) presenting with infiltration of large neoplastic lymphocytes into lumina of blood vessels, leading to vascular occlusion.[ncbi.nlm.nih.gov]
Generalized Lymphadenopathy
  • A 41-year-old woman manifested a polyneuropathy, anasarca, pseudotumor cerebri, hyperhidrosis and hyperpigmentation of the skin, generalized lymphadenopathy, distal esophageal dysphagia, pleuritis, platelike pulmonary atelectasis, fluctuating renal insufficiency[ncbi.nlm.nih.gov]
Pseudotumor
  • A 41-year-old woman manifested a polyneuropathy, anasarca, pseudotumor cerebri, hyperhidrosis and hyperpigmentation of the skin, generalized lymphadenopathy, distal esophageal dysphagia, pleuritis, platelike pulmonary atelectasis, fluctuating renal insufficiency[ncbi.nlm.nih.gov]
Pleural Effusion
  • Thus, large pleural effusions, especially chylous, without clear etiology should raise the suspicion for amyloidosis and lead to further investigations.[jhu.pure.elsevier.com]
  • Chest radiograph at that time revealed bilateral pleural effusions that were both reportedly milky in appearance when drained by thoracenteses.[ncbi.nlm.nih.gov]
  • Chest and abdomen CT showed massive bilateral pleural effusions, but no lung infiltrate, pericardial effusion or ascites or lymphadenopathy.[bloodjournal.org]
  • The pleural effusion persisted, the right lower limb edema worsened, and scrotal edema developed.[scielo.br]
Hepatosplenomegaly
  • […] woman manifested a polyneuropathy, anasarca, pseudotumor cerebri, hyperhidrosis and hyperpigmentation of the skin, generalized lymphadenopathy, distal esophageal dysphagia, pleuritis, platelike pulmonary atelectasis, fluctuating renal insufficiency, hepatosplenomegaly[ncbi.nlm.nih.gov]
Proximal Muscle Weakness
  • Abstract Dermatomyositis is an autoimmune disorder that causes proximal muscle weakness and skin changes which include generalized erythema, heliotrope rash and/or Gottron's papules.[ncbi.nlm.nih.gov]
Skin Lesion
  • We describe a patient with skin lesions and anasarca secondary to intestinal infection from Cryptococcus neoformans after heart transplantation. We based diagnosis on histologic examination of the cutaneous lesions and of the duodenal mucosa.[ncbi.nlm.nih.gov]
Cutaneous Manifestation
  • It is concluded that the generalized edema may appear as the presenting cutaneous manifestation of juvenile dermatomyositis.[ncbi.nlm.nih.gov]
Hyperhidrosis
  • A 41-year-old woman manifested a polyneuropathy, anasarca, pseudotumor cerebri, hyperhidrosis and hyperpigmentation of the skin, generalized lymphadenopathy, distal esophageal dysphagia, pleuritis, platelike pulmonary atelectasis, fluctuating renal insufficiency[ncbi.nlm.nih.gov]
Papule
  • Abstract Dermatomyositis is an autoimmune disorder that causes proximal muscle weakness and skin changes which include generalized erythema, heliotrope rash and/or Gottron's papules.[ncbi.nlm.nih.gov]
Hyperpigmentation
  • A 41-year-old woman manifested a polyneuropathy, anasarca, pseudotumor cerebri, hyperhidrosis and hyperpigmentation of the skin, generalized lymphadenopathy, distal esophageal dysphagia, pleuritis, platelike pulmonary atelectasis, fluctuating renal insufficiency[ncbi.nlm.nih.gov]
Facial Edema
  • One week prior to renal biopsy, he had the sudden onset of facial edema and a urine protein/creatinine ratio of 7.8. Image 1. No change by light microscopy. Image 2. Diffuse and complete foot process effacement.[arkanalabs.com]
  • The stem definitely mentioned "facial edema making it difficult for the patient to open his eyes in the morning" and "generalized body edema" with trace proteins and 50 RBCs on a UA.[forums.studentdoctor.net]
  • Periorbital and facial edema may also be associated. Although localized edema is a common feature of JDM, generalized edema has rarely been reported. Here, we report a 3.5-year-old boy with JDM presenting with generalized edema.[ncbi.nlm.nih.gov]
  • She has mild facial edema, moderate abdominal distention without … View Full Text Log in using your username and password Log in through your institution You may be able to gain access using your login credentials for your institution.[pedsinreview.aappublications.org]
Amenorrhea
  • […] polyneuropathy, anasarca, pseudotumor cerebri, hyperhidrosis and hyperpigmentation of the skin, generalized lymphadenopathy, distal esophageal dysphagia, pleuritis, platelike pulmonary atelectasis, fluctuating renal insufficiency, hepatosplenomegaly, amenorrhea[ncbi.nlm.nih.gov]
Tonic-Clonic Seizure
  • This report describes a 10-month-old infant who presented with generalised tonic clonic seizures following 2 days of vomiting, diarrhoea and a low-grade fever.[ncbi.nlm.nih.gov]

Workup

  • A recent workup for cardiac, renal, and liver disease, including two-dimensional echocardiogram, liver and renal function tests, and abdominal ultrasound, was unremarkable. He reported a 15-pack year history of smoking and quit 3 years ago.[ncbi.nlm.nih.gov]
Pericardial Effusion
  • […] failure (LV ejection fraction 55%) · Detects ventricular hypertrophy · Detects pericardial effusion Serum albumin · Reduced in hepatic disease and nephrotic syndrome · Unchanged in heart failure Liver function tests · Abnormal in cirrhosis (raised AST[tirthankaronline.blogspot.com]
  • Pericardial effusions were excluded by serial echocardiograms. The sums of the amplitude of QRS complexes from the 12 ECG leads (Sigma QRS) were correlated with the corresponding WTs.[ncbi.nlm.nih.gov]
  • Chest and abdomen CT showed massive bilateral pleural effusions, but no lung infiltrate, pericardial effusion or ascites or lymphadenopathy.[bloodjournal.org]
  • Pericardial effusion is the term for edema within the pericardial space between the outer layers of the heart. It is also known as a hydropericardium. Pulmonary edema is the term for edema within the lungs.[healthhype.com]
Thrombocytosis
  • The patient was moderately dehydrated and the blood investigations were remarkable for hyponatraemia (126 mEq/l), leukocytosis (19.4 10(3)/l (46% lymphocytes)), thrombocytosis (637 10(3)/l), hypoalbuminaemia (albumin 1.9 g/dl) and elevated C reactive[ncbi.nlm.nih.gov]
Nodular Glomerulosclerosis
  • Percutaneous renal biopsy showed nodular glomerulosclerosis, mesangial matrix expansion, and thickening of glomerular basement membrane (GBM). Immunofluorescence study showed no glomerular deposition of immunoglobulin or complement.[ncbi.nlm.nih.gov]
Pleural Effusion
  • Thus, large pleural effusions, especially chylous, without clear etiology should raise the suspicion for amyloidosis and lead to further investigations.[jhu.pure.elsevier.com]
  • Chest radiograph at that time revealed bilateral pleural effusions that were both reportedly milky in appearance when drained by thoracenteses.[ncbi.nlm.nih.gov]
  • Chest and abdomen CT showed massive bilateral pleural effusions, but no lung infiltrate, pericardial effusion or ascites or lymphadenopathy.[bloodjournal.org]
  • The pleural effusion persisted, the right lower limb edema worsened, and scrotal edema developed.[scielo.br]

Treatment

  • Pre- and post-treatment data were analyzed using matched pairs.[ncbi.nlm.nih.gov]
  • […] regimen that your doctor outlines for you • If your doctor prescribes any type of medication treatment, you should be certain to follow that treatment • Finally, you should review the treatment section of this guide and follow the steps outlined there[thehealthyapron.com]

Prognosis

  • Fetal hydrops is a known complication of sacrococcygeal teratoma (SCT) due to arteriovenous shunts within the tumor, which is clinically important and influence patients' prognosis.[ncbi.nlm.nih.gov]
  • Prognosis Multiple anecdotal remedies exist, yet none are proven or reported in scientific literature. Although survival rates are low, some water puppies do survive provided they receive immediate veterinary treatment.[embracepetinsurance.com]
  • Armitage JO, Longo DL: Clinical features, treatment, and prognosis of specific lymphoid malignancies; in Fauci A, Braunwald E, Kasper D, Hauser S, Longo D, Jameson J, Loscalzo J (eds): Harrison’s Principles of Internal Medicine, ed 15.[karger.com]

Etiology

  • Abstract Congo-red-negative microfibrils have been described in various glomerular diseases, some of which have no known etiology.[ncbi.nlm.nih.gov]
  • Anasarca of an Unusual Etiology. Abstract published at Hospital Medicine 2011, May 10-13, Dallas, Texas. Abstract 292. Journal of Hospital Medicine. 2011; 6 (suppl 2). .[shmabstracts.com]
  • EDEMA/ ANASARCA/ ANGIOEDEMA Etiologies The accumulation of fluid in the intercellular space of subcutaneous tissue or in body cavities is referred to as edema. Anasarca refers to a diffuse generalized edema of multiple organ systems.[thebigl.co]
  • Thus, large pleural effusions, especially chylous, without clear etiology should raise the suspicion for amyloidosis and lead to further investigations.[jhu.pure.elsevier.com]

Epidemiology

  • Epidemiology, pathophysiology, and treatment of Kaposi sarcoma-associated herpesvirus disease: Kaposi sarcoma, primary effusion lymphoma, and multicentric Castleman disease. Clin Infect Dis 2008 ; 47 : 1209 – 15. 12.[academic.oup.com]
  • Deep vein thrombosis of the axillary-subclavian veins: Epidemiologic data, effects of different types of treatment and late sequelae. Eur J Vasc Surg. 1988; 2 :161–5. [ PubMed ] [ Google Scholar ] 4. Snead D, Marberry KM, Rowdon G.[ncbi.nlm.nih.gov]
Sex distribution
Age distribution

Pathophysiology

  • Her severe cerebral edema is of considerable pathophysiologic interest: 1) it developed in the setting of marked anasarca and persistent hypernatremia, and 2) although hepatic function was poor, it was not considered sufficiently deranged to induce cerebral[ncbi.nlm.nih.gov]
  • Pathophysiology In the presence of hypoalbuminemia as seen in nephrotic syndrome or other disease entities, anasarca occurs as a result of low osmotic pressure in the capillaries.[healthfixit.com]
  • I'm thinking about the pathophysiology of the condition. The patient retains all this fluid because of underlying chemisty imbalances. Often low protein is at the heart of it.[allnurses.com]

Prevention

  • The American Academy of Pediatrics recommendations for prevention of iron deficiency anemia are reviewed.[ncbi.nlm.nih.gov]
  • Listed below are the effective treatments/ remedies for the prevention of anasarca that may help to improve and to reduce swelling of the skin significantly. 1. Avoiding salt, water pills, etc. – It prevent skin breakdown 2.[healthosphere.com]

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