Protease proteinase 3 (PR3) and myeloperoxidase (MPO) ANCA are present in almost all patients with MPA and GPA in the active generalized stage of the disease; in EGPA, ANCA are present in less than 40 percent and their presence is associated with typical [thermofisher.com]

We presented figures generated by the 'risk of bias' tool to provide summary assessments of the risk of bias. [cochranelibrary.com]

• Erythema

  These were one facial erythema and one transient bronchospasm that was described as severe and resulted in withdrawal from the trial. Two participants (one in the infliximab group, one in the rituximab group) experienced severe AEs and died. [cochranelibrary.com]

• Skin Rash

  During the additional long‐term follow‐up in the infliximab group, with mean time of follow‐up 30.6 ± 15.4 months and with all participants available, one participant had infliximab‐related skin rash; one participant experienced hepatitis subsequent to [cochranelibrary.com]

• Withdrawn

  GPA ‐ sensitivity BREVAS withdrawn due to adverse events Comparison 5. [cochranelibrary.com]

Chest 136:507–18 Article PubMed Google Scholar Bargagli E, Rottoli P (2008) Omalizumab treatment associated with Churg-Strauss vasculitis. [link.springer.com]

[…] skin Vasculitis diagnosis: Testing for differential diagnosis Prompt recognition of vasculitis either as a new presentation or a clinical relapse is key to optimizing management and preventing organ damage.6 The good news is that prompt diagnosis and treatment [thermofisher.com]

Newly diagnosed or relapsing ‐ as treatment effects may differ in participants receiving treatment for the first time and those receiving repeated treatment. Different dosage regimens ‐ different doses may show different treatment effects. [cochranelibrary.com]

A Staged approach to the treatment of Wegener’s granulomatosis: induction of remission with glucocorticoids and daily cyclophosphamide switching to methotrexate for remission maintenance. Arthritis Rheum. 1999;42(12):2666-73. [medigraphic.com]

CURRENT Diagnosis & Treatment: Nephrology & Hypertension. New York, NY: McGraw-Hill. [labtestsonline.it]

Presse Med 42:679–80 Article Google Scholar Cruz BA, Ramanoelina J, Mahr A, et al (2003) Prognosis and outcome of 26 patients with systemic necrotizing vasculitis admitted to the intensive care unit. [link.springer.com]

Renal vasculitic involvement is one of the most severe manifestations, with high mortality in case of a delayed diagnosis and a significant impact on patients’ long-term prognosis. [giornaleitalianodinefrologia.it]

Epidemiology and etiology of Wegener granulomatosis, microscopic polyangiitis, Churg-Strauss syndrome and Googpasture syndrome: vasculitides with frequent lung involvement Semin Respir Crit Care Med. 2011 Jun;32(3):264-73. doi: 10.1055/s-0031-1279824. [medigraphic.com]

Epidemiology of Wegener’s granulomatosis: lessons from descriptive studies and analyses of genetic and environmental risk determinants. Clin Exp Rheumatol. 2006 Mar-Apr;24(2 Suppl 41):S82-91. [medigraphic.com]

Prompt recognition of vasculitis either as a new presentation or a clinical relapse is key to optimizing management and preventing organ damage.6 ANCA-associated vasculitides Vasculitis is a condition that causes inflammation of vessel walls.3 ANCA-associated [thermofisher.com]