Abstract A case of a 17-year-old patient diagnosed with bilateral androblastoma of the ovary is presented. The patient was admitted because of secondary amenorrhea, hirsutism and acne. [ncbi.nlm.nih.gov]

While they can present at any age, they typically present <30 years old, with a mean age of 14 years. In ~30-50% of patients, the presenting symptoms are related to clinical signs of androgenic activity 6. [radiopaedia.org]

In males, the presenting symptom is a slow growing testicular mass. Most cases follow a benign clinical course. In females it may present with estrogenic or androgenic manifestations. The vast majority of cases have a benign clinical course. [codes.iarc.fr]

• Tonsillar Mass

  Electron microscopic study of the tonsillar mass revealed crystalloid structures suggestive of the Leydig cell origin of the tumor. [scite.ai]

• Body Hair Increased

  Symptoms This tumor secretes male hormones which causes secondary sex changes in women including: deepening of the voice increased facial and body hair increased size of the clitoris male pattern baldness Signs and tests ultrasound of the ovaries CT scan [health.am]

• Amenorrhea

  The recommendation to include the measurement of androgen levels in the routine diagnosis of secondary amenorrhea must therefore be endorsed. [ncbi.nlm.nih.gov]

  […] ovary Disease definition Malignant Sertoli-Leydig cell tumor of ovary is a rare malignant sex cord stromal tumor of ovary (see this term) occuring typically in young women and characterized by manifestations of androgen excess (hirsutism, hair loss, amenorrhea [orpha.net]

In addition, every medical doctor should always try to perform thorough medical workup of his patients in order to avoid overlooking tiny, but sometimes crucial, aspects leading to diagnosis. [hindawi.com]

• Testosterone Decreased

  When performing blood tests on hormones at patients with androblastomy an ovary increase in level of testosterone, decrease in level of lyuteineziruyushchy and follikulstimuliruyushchy hormone comes to light. [medicine-for-you.com]

Treatment Surgical removal of the affected ovary is the most common treatment -- and usually all the treatment that is necessary. That's because more than 75% of these tumors are found early (grade I) and in only one ovary. [verywell.com]

Treatment Surgery is done to remove one or both ovaries. If the tumor is advanced stage, chemotherapy or radiation therapy may be done after surgery. Outlook (Prognosis) Early treatment results in a good outcome. [pennstatehershey.adam.com]

Androblastoma of an ovary - treatment [medicine-for-you.com]

[…] to advances in diagnosis and treatment. [rarediseases.info.nih.gov]

prognosis compared with those with poor health Age of the individual: Older individuals generally have poorer prognosis than younger individuals Whether the tumor is occurring for the first time, or is a recurrent tumor. [dovemed.com]

Prognosis In general, the prognosis (long-term outlook) and chances for a cure depend upon the stage and grade of the tumor. By definition, all tumors that have spread beyond the ovary are considered malignant (or cancerous). [verywell.com]

Outlook (Prognosis) Prognosis of SLCT depends on the stage and degree of differentiation of the tumor. Since these tumors are typically benign and their growth is slow, outlook is generally very positive. [knowcancer.com]

Wegener granulomatosis - Autoimmune etiology and clinical course. Diabetes - disease and management information, including diagnosis, typical treatment plans and diabetes supplies. [netdoc.com]

[…] blood CF cerebrospinal fluid CI chemically induced CH chemistry CL classification CO complications CN congenital DI diagnosis DG diagnostic imaging DH diet therapy DT drug therapy EC economics EM embryology EN enzymology EP epidemiology EH ethnology ET etiology [decs.bvs.br]

English: BS blood supply BL blood CF cerebrospinal fluid CI chemically induced CH chemistry CL classification CO complications CN congenital DI diagnosis DG diagnostic imaging DH diet therapy DT drug therapy EC economics EM embryology EN enzymology EP epidemiology [decs.bvs.br]

Definition / general Sex cord stromal tumor of testis composed of cells expressing, to a varying degree, features of fetal, prepubertal or adult Sertoli cells Terminology Also called androblastoma Epidemiology < 1% of testicular tumors Occurs in normally [pathologyoutlines.com]

Sertoli–Leydig cell tumor group Epidemiology Sertoli-Leydig cell tumors are uncommon benign tumors, accounting for less than 0.5% of all ovarian tumors. [emedicine.medscape.com]

All patients were reported between 2004 and 2013 in the Surveillance, Epidemiology, and End Results (SEER) database. [ncbi.nlm.nih.gov]

Signs and Symptoms (Pathophysiology) Symptoms can include infrequent or no menstrual periods, the development of facial hair, a hoarse voice, increased muscle mass, acne, and clitoromegaly. [knowcancer.com]

Prevention There are no known ways to prevent ovarian cancer of any kind, as the cause is unknown. [azkrmc.com]

Prevention There are no known ways to prevent ovarian cancer of any kind, as the cause is unknown. References Choong S, Fuller P, et al. Sertoli-Leydig cell tumor of the ovary, a rare cause of precocious puberty in a 12-month-old infant. [wkhs.com]

Prevention There are no known ways to prevent ovarian cancer of any kind, as the cause is unknown. References: Choong S, Fuller P, et al. Sertoli-Leydig cell tumor of the ovary, a rare cause of precocious puberty in a 12-month-old infant. [whc-shreveport.com]

Prevention There are no known ways to prevent ovarian cancer of any kind, as the cause is unknown. Choong S, Fuller P, et al. Sertoli-Leydig cell tumor of the ovary, a rare cause of precocious puberty in a 12-month-old infant. [stjosepheureka.myhospitalwebsite.com]