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Androblastoma

Sertoli-Leydig Cell Tumor


Presentation

  • A case of a 17-year-old patient diagnosed with bilateral androblastoma of the ovary is presented. The patient was admitted because of secondary amenorrhea, hirsutism and acne.[ncbi.nlm.nih.gov]
  • While they can present at any age, they typically present In 30-50% of patients, the presenting symptoms are related to clinical signs of androgenic activity 6 .[radiopaedia.org]
Chills
  • Related Posts Recent Posts Sarcoma Awareness Month July 2019 July 30, 2019 Read More Nutrition Spotlight: Chilling and Grilling in the Summertime: What to Know July 29, 2019 Read More Virginia Cancer Specialists Enhances World-Class Breast Surgery Services[virginiacancerspecialists.com]
Tonsillar Mass
  • Electron microscopic study of the tonsillar mass revealed crystalloid structures suggestive of the Leydig cell origin of the tumor.[scite.ai]
Forgetful
  • Forget about any signups or registrations. Quickly and comfortably change ... Definition of androblastoma - NCI Dictionary of Cancer Terms ... ; A rare type of ovarian tumor in which the tumor cells secrete a male sex hormone.[yguuqoxl.gq]
Amenorrhea
  • The patient was admitted because of secondary amenorrhea, hirsutism and acne.[ncbi.nlm.nih.gov]
  • […] ovary Disease definition Malignant Sertoli-Leydig cell tumor of ovary is a rare malignant sex cord stromal tumor of ovary (see this term) occuring typically in young women and characterized by manifestations of androgen excess (hirsutism, hair loss, amenorrhea[orpha.net]

Workup

Testosterone Decreased
  • When performing blood tests on hormones at patients with androblastomy an ovary increase in level of testosterone, decrease in level of lyuteineziruyushchy and follikulstimuliruyushchy hormone comes to light.[medicine-for-you.com]

Treatment

  • Treatment Surgical removal of the affected ovary is the most common treatment -- and usually all the treatment that is necessary. That's because more than 75% of these tumors are found early (grade I) and in only one ovary.[verywell.com]
  • Treatment Surgery is done to remove one or both ovaries. If the tumor is advanced stage, chemotherapy or radiation therapy may be done after surgery. Outlook (Prognosis) Early treatment results in a good outcome.[pennstatehershey.adam.com]
  • Androblastoma of an ovary - treatment[medicine-for-you.com]
  • Treatment Treatment involves surgery to remove one or both ovaries. This procedure is usually successful in returning normal menstruation (in premenopausal women) and ceasing masculinization.[wkhs.com]

Prognosis

  • Biologically it follows a low-malignant course with a fair prognosis, long-term complex patient follow up is necessary after unilateral oophorectomy of the diseased organ.[hungary.pure.elsevier.com]
  • prognosis compared with those with poor health Age of the individual: Older individuals generally have poorer prognosis than younger individuals Whether the tumor is occurring for the first time, or is a recurrent tumor.[dovemed.com]
  • Outlook (Prognosis) Prognosis of SLCT depends on the stage and degree of differentiation of the tumor. Since these tumors are typically benign and their growth is slow, outlook is generally very positive.[knowcancer.com]

Etiology

  • […] blood CF cerebrospinal fluid CI chemically induced CH chemistry CL classification CO complications CN congenital DI diagnosis DG diagnostic imaging DH diet therapy DT drug therapy EC economics EM embryology EN enzymology EP epidemiology EH ethnology ET etiology[decs.bvs.br]
  • Wegener granulomatosis - Autoimmune etiology and clinical course. Diabetes - disease and management information, including diagnosis, typical treatment plans and diabetes supplies.[netdoc.com]
  • Etiology and features of a structure of an androblastoma of an ovary The reasons of development of an androblastoma of an ovary are unknown.[medicine-for-you.com]

Epidemiology

  • English : BS blood supply BL blood CF cerebrospinal fluid CI chemically induced CH chemistry CL classification CO complications CN congenital DI diagnosis DG diagnostic imaging DH diet therapy DT drug therapy EC economics EM embryology EN enzymology EP epidemiology[decs.bvs.br]
  • Definition / general Sex cord stromal tumor of testis composed of cells expressing, to a varying degree, features of fetal, prepubertal or adult Sertoli cells Terminology Also called androblastoma Epidemiology 1% of testicular tumors Occurs in normally[pathologyoutlines.com]
  • Sertoli–Leydig cell tumor group Epidemiology Sertoli-Leydig cell tumors are uncommon benign tumors, accounting for less than 0.5% of all ovarian tumors.[emedicine.medscape.com]
Sex distribution
Age distribution

Pathophysiology

  • Signs and Symptoms (Pathophysiology) Symptoms can include infrequent or no menstrual periods, the development of facial hair, a hoarse voice, increased muscle mass, acne, and clitoromegaly.[knowcancer.com]

Prevention

  • Prevention There are no known ways to prevent ovarian cancer of any kind, as the cause is unknown.[azkrmc.com]
  • Prevention There are no known ways to prevent ovarian cancer of any kind, as the cause is unknown. References Choong S, Fuller P, et al. Sertoli-Leydig cell tumor of the ovary, a rare cause of precocious puberty in a 12-month-old infant.[wkhs.com]
  • Prevention There are no known ways to prevent ovarian cancer of any kind, as the cause is unknown. References: Choong S, Fuller P, et al. Sertoli-Leydig cell tumor of the ovary, a rare cause of precocious puberty in a 12-month-old infant.[whc-shreveport.com]
  • Prevention There are no known ways to prevent ovarian cancer of any kind, as the cause is unknown. Choong S, Fuller P, et al. Sertoli-Leydig cell tumor of the ovary, a rare cause of precocious puberty in a 12-month-old infant.[stjosepheureka.myhospitalwebsite.com]

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