Neonates are generally pale and, if anemia is severe, have tachypnea, tachycardia, and sometimes a flow murmur; hypotension is present with acute blood loss. Jaundice may be present with hemolysis. [merckmanuals.com]

• Hypertension

  Side effects reported in adults include hypertension, bone pain, rash and rarely seizures. Only transient neutropenia has been reported in neonates (Ohls 2000). [cochranelibrary.com]

Early treatment with EPO did not confer any major benefits compared with late EPO treatment. [cochranelibrary.com]

Need for treatment varies with degree of anemia and associated medical conditions. Mild anemia in otherwise healthy term and preterm infants generally does not require specific treatment; treatment is directed at the underlying diagnosis. [merckmanuals.com]

After birth, some infections (such as cytomegalovirus infection, syphilis, and human immunodeficiency virus [HIV]) may also prevent the bone marrow from producing enough red blood cells. [merckmanuals.com]

Low plasma EPO levels provide a rationale for use of EPO in the prevention or treatment of anaemia of prematurity. [cochranelibrary.com]