Presentation
This article presents an in-depth discussion of a case involving a nearly 10-year-old boy with a history of an unspecified form of MD, who presented for endodontic treatment of tooth No. 30 under deep sedation. [ncbi.nlm.nih.gov]
Entire Body System
- Hypothermia
Chills and shivering (hypothermia) – This occurs in up to half of patients as they regain consciousness after surgery, and it might be related to body temperature. [asahq.org]
Severe hypothermia may result in coagulopathy, delayed awakening, or arrhythmia. [emedicine.medscape.com]
More likely is the occurrence of intraoperative hypothermia due to a combination of four types of heat loss: conductive, convective, evaporative and radiant. [tsaco.bmj.com]
- Inguinal Hernia
I am having a right inguinal hernia repair, without any type of complication. What type of anesthesia do you most recommend? We recommend a field block with local anesthetics for uncomplicated repair of an Inguinal Hernia. [sambahq.org]
Pharmacokinetics and pharmacodynamics of ropivacaine 2 mg/mL, 5 mg/mL, or 7.5 mg/mL after ilioinguinal blockade for inguinal hernia repair in adults. Anesth Analg. 1999;89(6):1471–4. 25. [bmcanesthesiol.biomedcentral.com]
- Fatigue
He also saw it as a drug capable of curing most of the ailments of modern life: fatigue, indigestion, low spirits. It was the cure for what ails you. [wired.com]
Patients with Chronic Fatigue Syndrome are known to have reactivated herpes group viruses which can produce mild and usually subclinical hepatitis. Hepatotoxic anesthetic gases may then provoke fulminate hepatitis. [anapsid.org]
- Pallor
Vacuolization of the basal and suprabasilar layer, pallor and swelling of upper layer epidermal keratinocytes, a pauci-inflammatory cleavage beneath or within the basal layer, basophilic granular karyorrhectic debris in the subepidermal cleft, and congestion [ncbi.nlm.nih.gov]
- Intravenous Administration
& dosage Anesthetics, Local/poisoning* Antidotes/administration & dosage* Cesarean Section Fat Emulsions, Intravenous/administration & dosage* Female Humans Infusions, Spinal Lidocaine/administration & dosage Lidocaine/poisoning* Poisoning/diagnosis [ncbi.nlm.nih.gov]
Subscribe today Rapid, safe, and well-controlled anesthesia can be obtained by the intravenous administration of depressants of the central nervous system, such as the barbiturates (e.g., thiopental), the benzodiazepines (e.g., midazolam), or other drugs [britannica.com]
Gastrointestinal
- Vomiting
This is to prevent you from vomiting while you are under the effect of the anesthesia. Vomiting can cause food in the stomach to be inhaled into the lungs. This can lead to breathing problems. [medlineplus.gov]
Warriner’s research is focused on the use of blood substitutes in surgical patients, the value of preoperative beta blockers, the reversal of muscle relaxants and the prevention of postoperative nausea and vomiting. ► LECTURIO is your single-point resource [youtube.com]
Patients given monitored anesthesia rather than general anesthesia experience fewer incidences of nausea and vomiting and typically can be discharged home safely and quickly. The image below depicts intraoral approach for an infraorbital block. [emedicine.medscape.com]
Because of irregular breathing and a risk of vomiting, there is a danger of choking. [medicalnewstoday.com]
- Nausea
Rate/drug effects Humans Hypotension/chemically induced Hypotension/drug therapy Injections, Epidural/adverse effects Lidocaine/administration & dosage Lidocaine/adverse effects* Lumbosacral Plexus/drug effects* Middle Aged Monitoring, Intraoperative Nausea [ncbi.nlm.nih.gov]
While side effects differ based on the substance (e.g., halothane can cause hepatotoxicity), the most common side effect is nausea. [amboss.com]
Warriner’s research is focused on the use of blood substitutes in surgical patients, the value of preoperative beta blockers, the reversal of muscle relaxants and the prevention of postoperative nausea and vomiting. ► LECTURIO is your single-point resource [youtube.com]
Patients given monitored anesthesia rather than general anesthesia experience fewer incidences of nausea and vomiting and typically can be discharged home safely and quickly. The image below depicts intraoral approach for an infraorbital block. [emedicine.medscape.com]
Side effects Nausea is a common side effect of general anesthesia. There are a number of potential side effects of anesthesia. Some individuals may experience none, others a few. [medicalnewstoday.com]
- Abdominal Pain
Pain control and advice An anesthesiologist who specializes in pain medicine may assist patients who have pain due to a range of causes, including headaches, burns, diabetes and herpes, or where they are experiencing chest pain, abdominal, pain pelvic [medicalnewstoday.com]
Celiac Plexus Block : A celiac plexus block is generally performed to relieve pain in patients with cancer of the pancreas or other chronic abdominal pains. [asra.com]
Skin
- Dermatitis
A second biopsy without topical anesthetic did not demonstrate a bulla and supported the clinical diagnosis of psoriasiform dermatitis. [ncbi.nlm.nih.gov]
‘Contact dermatitis in the ear canal can result from almost any local irritant, including topical anti-infective agents and anesthetics and other topical preparations.’ [oxforddictionaries.com]
Urogenital
- Cesarean Section
She subsequently underwent cesarean delivery under spinal anesthesia for failure to progress without sequelae in the mother or infant. [ncbi.nlm.nih.gov]
If a cesarean section is needed, stronger anesthetics can be given in the same location, to numb the lower body completely for surgery. If severe complications arise, the anesthesiologist may need to provide a general anesthesia. [medicalnewstoday.com]
Neurologic
- Seizure
Close attention was directed to cardiac function, seizure, and airway management. [ncbi.nlm.nih.gov]
Thiopental also is sometimes used to control convulsions (seizures) caused by certain medicines or seizure disorders. Thiopental may be used to reduce pressure on the brain in certain conditions. [mayoclinic.org]
- Confusion
Postoperative delirium – Confusion when regaining consciousness after surgery is common, but for some people — particularly older patients — the confusion can come and go for about a week. [asahq.org]
Other common side effects from the medicine are: Nausea and vomiting Dry mouth Sore throat Hoarse voice Sleepiness Shivering Muscle aches Itching Confusion -- especially in older people Rarely, people can be very confused for a few days after their surgery [webmd.com]
It can induce a condition known as postoperative delirium, a state of serious confusion and memory loss. [io9.gizmodo.com]
- Amnesia
Under general anesthesia, the patient is unable to feel pain and may also have amnesia. [medicalnewstoday.com]
While under general anesthesia, a patient is unable to feel pain and will likely wake with some short-term amnesia (memory loss). Experts are unsure exactly how general anesthetics work. [drugs.com]
The authors sought to determine whether unconsciousness and amnesia occur when humans develop rigidity and apnea after intravenous fentanyl (without other concomitant anesthetics). [doi.org]
Since then, doctors have gotten much better at putting us out with drug combinations that ease pain, relax muscles and, in some cases, put us in a deep state of hypnosis that gives us temporary amnesia. [livescience.com]
- Convulsions
There is wide practice variation in choice of third line therapy for RSE, but there is overall consensus that anesthetics should be initiated earlier in generalized convulsive status epilepticus than in nonconvulsive forms. [ncbi.nlm.nih.gov]
[…] indicated for the induction of anesthesia and supplementation of subpotent anesthesia during short operative procedures.DB00474MethohexitalAn anesthetic used to induce deep sedation.DB00599ThiopentalA barbiturate used to induce general anesthesia, treat convulsions [drugbank.ca]
Thiopental also is sometimes used to control convulsions (seizures) caused by certain medicines or seizure disorders. Thiopental may be used to reduce pressure on the brain in certain conditions. [mayoclinic.org]
It is possible to have adverse reactions to local anesthetics, such as dizziness, hypotension (low blood pressure ), convulsions, and even death. [encyclopedia.com]
- Temporary Amnesia
Since then, doctors have gotten much better at putting us out with drug combinations that ease pain, relax muscles and, in some cases, put us in a deep state of hypnosis that gives us temporary amnesia. [livescience.com]
Treatment
We describe the perioperative management of a complex pediatric patient undergoing a posterior tracheopexy which is a relatively new surgical treatment, with a novel surgical approach-thoracoscopy. [ncbi.nlm.nih.gov]
Prognosis
The resulting prognosis can be excellent after the rapid removal of inciting agents and the application of appropriate treatments. [ncbi.nlm.nih.gov]
This content is for informational purposes only and does not substitute for formal and individualized diagnosis, prognosis, treatment, prescription, and/or dietary advice from a licensed medical professional. [healdove.com]
Etiology
[…] poisoning* Antidotes/administration & dosage* Cesarean Section Fat Emulsions, Intravenous/administration & dosage* Female Humans Infusions, Spinal Lidocaine/administration & dosage Lidocaine/poisoning* Poisoning/diagnosis Poisoning/drug therapy* Poisoning/etiology [ncbi.nlm.nih.gov]
Epidemiology
The results of single-center and multicenter registries and epidemiologic studies complement this information. Between March 2014 and November 2016, 47 separate cases of LAST were described in 35 peer-reviewed articles. [ncbi.nlm.nih.gov]
In humans, recent preliminary findings from epidemiological studies suggest an association between surgery and anesthesia early in life and subsequent learning abnormalities. [doi.org]
This may have been a chance finding, as analyses did not adjust for multiple endpoints.43 The PANDA study addressed many of the limitations of the previous epidemiologic studies. [fda.gov]
Pathophysiology
Obstetric and anesthetic management are particularly challenging, and treatment requires knowledge of pathophysiologic mechanisms in order to provide safe care to this group of patients. [ncbi.nlm.nih.gov]
[…] hypertension Desflurane: sympatho-adrenergic reaction → ↑ blood pressure and ↑ heart rate Sevoflurane: interacts with soda lime → nephrotoxic breakdown products (known as compounds A–E) Enflurane: proconvulsive Halothane: hepatotoxic → halothane hepatitis [5] Pathophysiology [amboss.com]
Pathophysiological effects during laparoscopic cholecystectomy 2.1. [intechopen.com]
Prevention
Spontaneous spinal epidural hematoma during pregnancy is a quite rare event requiring emergent decompressive surgery in the majority of cases to prevent permanent neurological damage. [ncbi.nlm.nih.gov]
The scavenging system should be kept in good repair to prevent leaks using a maintenance and inspection program as listed below. [ccohs.ca]