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Anesthetic
Agents Anesthetic

Presentation

This article presents an in-depth discussion of a case involving a nearly 10-year-old boy with a history of an unspecified form of MD, who presented for endodontic treatment of tooth No. 30 under deep sedation. [ncbi.nlm.nih.gov]

Entire Body System

  • Hypothermia

    Chills and shivering (hypothermia) – This occurs in up to half of patients as they regain consciousness after surgery, and it might be related to body temperature. [asahq.org]

    Severe hypothermia may result in coagulopathy, delayed awakening, or arrhythmia. [emedicine.medscape.com]

    More likely is the occurrence of intraoperative hypothermia due to a combination of four types of heat loss: conductive, convective, evaporative and radiant. [tsaco.bmj.com]

  • Fatigue

    He also saw it as a drug capable of curing most of the ailments of modern life: fatigue, indigestion, low spirits. It was the cure for what ails you. [wired.com]

    Patients with Chronic Fatigue Syndrome are known to have reactivated herpes group viruses which can produce mild and usually subclinical hepatitis. Hepatotoxic anesthetic gases may then provoke fulminate hepatitis. [anapsid.org]

Gastrointestinal

  • Nausea

    Rate/drug effects Humans Hypotension/chemically induced Hypotension/drug therapy Injections, Epidural/adverse effects Lidocaine/administration & dosage Lidocaine/adverse effects* Lumbosacral Plexus/drug effects* Middle Aged Monitoring, Intraoperative Nausea [ncbi.nlm.nih.gov]

    While side effects differ based on the substance (e.g., halothane can cause hepatotoxicity), the most common side effect is nausea. [amboss.com]

    Patients given monitored anesthesia rather than general anesthesia experience fewer incidences of nausea and vomiting and typically can be discharged home safely and quickly. The image below depicts intraoral approach for an infraorbital block. [emedicine.medscape.com]

    Regional anesthesia is the preferred anesthetic technique for patients undergoing orthopedic surgery because it is associated with less postoperative pain and nausea, a lower incidence of blood clots, less blood loss, and a lower infection rate compared [hss.edu]

    Side effects Nausea is a common side effect of general anesthesia. There are a number of potential side effects of anesthesia. Some individuals may experience none, others a few. [medicalnewstoday.com]

  • Abdominal Pain

    Pain control and advice An anesthesiologist who specializes in pain medicine may assist patients who have pain due to a range of causes, including headaches, burns, diabetes and herpes, or where they are experiencing chest pain, abdominal, pain pelvic [medicalnewstoday.com]

    Celiac Plexus Block : A celiac plexus block is generally performed to relieve pain in patients with cancer of the pancreas or other chronic abdominal pains. [asra.com]

Neurologic

  • Confusion

    Postoperative delirium – Confusion when regaining consciousness after surgery is common, but for some people — particularly older patients — the confusion can come and go for about a week. [asahq.org]

    It can induce a condition known as postoperative delirium, a state of serious confusion and memory loss. [io9.gizmodo.com]

    Other common side effects from the medicine are: Nausea and vomiting Dry mouth Sore throat Hoarse voice Sleepiness Shivering Muscle aches Itching Confusion -- especially in older people Rarely, people can be very confused for a few days after their surgery [webmd.com]

  • Amnesia

    Under general anesthesia, the patient is unable to feel pain and may also have amnesia. [medicalnewstoday.com]

    While under general anesthesia, a patient is unable to feel pain and will likely wake with some short-term amnesia (memory loss). Experts are unsure exactly how general anesthetics work. [drugs.com]

    The authors sought to determine whether unconsciousness and amnesia occur when humans develop rigidity and apnea after intravenous fentanyl (without other concomitant anesthetics). [doi.org]

    Purpose General anesthesia is intended to bring about five distinct states during surgery: analgesia, or pain relief amnesia, or loss of memory of the procedure loss of consciousness motionlessness weakening of autonomic responses General Anesthesia Precautions [henryschein.com]

  • Temporary Amnesia

    Since then, doctors have gotten much better at putting us out with drug combinations that ease pain, relax muscles and, in some cases, put us in a deep state of hypnosis that gives us temporary amnesia. [livescience.com]

  • Stupor

    Opium was praised by the Persian philosopher and physician Avicenna in the eleventh century as the most powerful of stupor-producing substances. [encyclopedia.com]

Workup

Rhythm

  • Sinus Arrest

    Injection of local anesthetic into the empty orbit induced an extended sinus arrest. This exaggerated response was avoided in a subsequent surgery by pretreatment with high-dose anticholinergics. [ncbi.nlm.nih.gov]

Treatment

We describe the perioperative management of a complex pediatric patient undergoing a posterior tracheopexy which is a relatively new surgical treatment, with a novel surgical approach-thoracoscopy. [ncbi.nlm.nih.gov]

Prognosis

The resulting prognosis can be excellent after the rapid removal of inciting agents and the application of appropriate treatments. [ncbi.nlm.nih.gov]

This content is for informational purposes only and does not substitute for formal and individualized diagnosis, prognosis, treatment, prescription, and/or dietary advice from a licensed medical professional. [healdove.com]

Etiology

[…] poisoning* Antidotes/administration & dosage* Cesarean Section Fat Emulsions, Intravenous/administration & dosage* Female Humans Infusions, Spinal Lidocaine/administration & dosage Lidocaine/poisoning* Poisoning/diagnosis Poisoning/drug therapy* Poisoning/etiology [ncbi.nlm.nih.gov]

Epidemiology

The results of single-center and multicenter registries and epidemiologic studies complement this information. Between March 2014 and November 2016, 47 separate cases of LAST were described in 35 peer-reviewed articles. [ncbi.nlm.nih.gov]

In humans, recent preliminary findings from epidemiological studies suggest an association between surgery and anesthesia early in life and subsequent learning abnormalities. [doi.org]

This may have been a chance finding, as analyses did not adjust for multiple endpoints.43 The PANDA study addressed many of the limitations of the previous epidemiologic studies. [fda.gov]

Pathophysiology

Obstetric and anesthetic management are particularly challenging, and treatment requires knowledge of pathophysiologic mechanisms in order to provide safe care to this group of patients. [ncbi.nlm.nih.gov]

[…] hypertension Desflurane: sympatho-adrenergic reaction → ↑ blood pressure and ↑ heart rate Sevoflurane: interacts with soda lime → nephrotoxic breakdown products (known as compounds A–E) Enflurane: proconvulsive Halothane: hepatotoxic → halothane hepatitis [5] Pathophysiology [amboss.com]

Pathophysiological effects during laparoscopic cholecystectomy 2.1. [intechopen.com]

Prevention

Spontaneous spinal epidural hematoma during pregnancy is a quite rare event requiring emergent decompressive surgery in the majority of cases to prevent permanent neurological damage. [ncbi.nlm.nih.gov]

The scavenging system should be kept in good repair to prevent leaks using a maintenance and inspection program as listed below. [ccohs.ca]

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